Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05257629RecruitingPhase 3
Aggressive smoking quit program after heart problems
This trial tests whether a strong quit plan using varenicline (a quit pill) plus nicotine e-cigarettes, along with counseling, helps people stop smoking after a recent heart-related event. It’s aimed at people who want to quit and can safely stay involved for about a year.
New Westminster, British ColumbiaAges 18 years+ - NCT05258981Recruiting
MRI and testing study linking genes and thinking in adults
This study looks at how patterns on brain MRI scans and genes relate to thinking and test performance in adults. It may help researchers better understand long-term brain and cognitive outcomes and how they differ between people with specific early-life heart conditions and healthy controls.
Boston, MassachusettsAges 24–35 - NCT05258448Recruiting
Chemo-radiotherapy for advanced, non-surgical lung cancer
This trial studies treatment that combines chemotherapy and radiation for people with advanced lung cancer that cannot be removed with surgery. It may help improve cure chances for patients who can complete the study tests, including heart scans.
Odense CAges 18 years+ - NCT05259553Recruiting
Testing blood markers in newly diagnosed multiple myeloma
This study looks at “biomarkers,” or measurable signals in blood, in people with multiple myeloma who are being treated for the first time. It may help researchers understand the disease better and how it responds to treatment.
LyonAges 18 years+ - NCT05260125RecruitingPhase 4
Ultrasound-guided shoulder nerve block for stroke pain
This trial compares two ways to deliver a shoulder nerve block to relieve long-lasting shoulder pain after stroke: one guided by ultrasound and one without. It may help if your stroke-related shoulder pain has lasted at least a few months and you may benefit from a targeted pain-relief injection.
BoluAges 25–75 - NCT05262803RecruitingPhase 4
Lower blood-thinner dose after heart attack for high bleeding risk
This Phase 4 study tests whether using a reduced blood-thinner (antithrombotic) strategy after a heart attack can lower bleeding without losing heart protection. It is mainly for people considered high risk for bleeding after getting a stent.
AalborgAges 18 years+ - NCT05262907Recruiting
Study of heart imaging in people with one pumping ventricle
This study uses routine heart scans (either echocardiogram or MRI) to better understand single-ventricle heart conditions. It may help improve how doctors evaluate and monitor your heart over time.
Durham, North CarolinaAges Any age - NCT05263804Recruiting
Study uses MRI and blood clues after ischemic stroke
This study looks for biological and imaging markers that may predict heart/vascular outcomes after an ischemic stroke. You may join if you are eligible for standard stroke treatment and can complete planned follow-up and MRI scans.
BronAges 18 years+ - NCT05264753Recruiting
Follow-up study for a device that closes an abnormal heart blood vessel
This study checks how well and how safely the Occlutech PDA Occluder works over time to close a patent ductus arteriosus (PDA). You may be considered if your PDA can be treated with this non-surgical device and you can return for follow-up visits.
MontrealAges Any age - NCT05264831Recruiting
Ablation treatment after failed electric heart shock
This trial tests whether blocking faulty heart signals from the pulmonary veins (with or without additional “substrate” modification) works better when electric cardioversion doesn’t stop persistent atrial fibrillation. It may help people who remain in atrial fibrillation after cardioversion by reducing symptoms and abnormal rhythm over time.
Caluire-et-CuireAges 18–80 - NCT05266092Recruiting
Study kidney disease immune system activity in dialysis patients
This study looks at how the body’s defense systems (immune system and related signals) behave in people with chronic kidney disease. It may help doctors understand what is driving inflammation and related complications in dialysis patients.
OdenseAges 18 years+ - NCT05266144Recruiting
Catheter ablation for non-valvular atrial fibrillation
This trial studies catheter ablation, a procedure that targets heart rhythm triggers, for people with atrial fibrillation (an irregular heartbeat). It may help improve rhythm control, but you must meet specific heart and testing requirements and avoid certain conditions.
Beijing, Beijing MunicipalityAges 18–80 - NCT05265520Recruiting
Pacing strategy study for certain heart failure patients
This trial tests a pacing approach designed to improve how the heart beats in some people with heart failure and a specific heart rhythm pattern on ECG. If you already need a device (CRT-D) based on your results, the study may help see whether this pacing correction improves outcomes.
Phoenix, ArizonaAges 18 years+ - NCT05267184Recruiting
Embolization versus surgery for long-term brain blood collections
This trial compares two ways to treat a chronic subdural hematoma (a long-lasting bleed between the brain and its covering): blocking a specific artery versus standard surgery to remove the blood. It may help you and your care team choose the safer and more effective option for your situation.
GothenburgAges 18–89 - NCT05267886RecruitingPhase 4
Testing an inotrope medicine versus placebo in shock patients
This trial studies whether an inotrope medicine (a drug that helps the heart pump) works better than a placebo in adults in intensive care with cardiogenic shock. It may help doctors find safer, more effective treatment for this life-threatening condition.
Rochester, MinnesotaAges 18 years+ - NCT05268861Recruiting
Understanding brain learning after stroke during arm training
This study looks at how thinking and brain processes affect learning to move your arm after a stroke. You may be asked to do arm tasks in a way that helps the researchers understand what helps or limits motor learning.
Laval, QuebecAges 40–75 - NCT05272618Recruiting
Testing heart vessel dysfunction after a heart attack
This trial looks at how to assess small blood-vessel (microvascular) problems in people who had a heart attack but whose main heart arteries are not blocked. It may help doctors better find what’s driving symptoms and choose the right tests and treatments.
Gwangju, GwangjuAges 19 years+ - NCT05272826RecruitingPhase 2
New, untreated myeloma study using four medicines
This Phase 2 trial tests a combination of medicines (iberdomide, bortezomib, dexamethasone, and adding isatuximab) for people with newly diagnosed multiple myeloma who cannot have a transplant. The goal is to improve disease control while checking safety in older adults who can take pills and attend frequent visits.
Edmonton, AlbertaAges 65 years+ - NCT05273216Recruiting
Study blood vessel injury after clot removal for stroke
This trial looks at how blood flow damage (“reperfusion injury”) happens after mechanical clot removal in certain stroke types. It may help doctors better prevent complications after the procedure.
Graz, StyriaAges 18 years+ - NCT05277129Recruiting
Study of the immune response soon after stroke
This study looks at how your body’s immune system reacts in the first hours after a stroke. It may help researchers understand stroke-related immune changes and improve future treatments.
LørenskogAges 18 years+ - NCT05281055Recruiting
Registry of clot-removal treatment for sudden large-vessel strokes
This study keeps a record of people treated with a clot-removal procedure (endovascular thrombectomy) for a sudden stroke caused by a blocked large blood vessel in the brain. It focuses on outcomes for patients who can be treated within 24 hours and were independent before the stroke.
TaipeiAges 20 years+ - NCT05281887Recruiting
Study of eye changes after ischemic stroke
This trial looks at how changes in the retina (the light-sensing tissue in the back of the eye) track with vision and eye function after an ischemic stroke. The goal is to understand which eye changes are linked to the stroke, which could help doctors monitor recovery.
Guangzhou, GuangdongAges 18 years+ - NCT05283993Recruiting
Hospital study following people with plasma cell disorders
This is a hospital-based study that follows people with plasma cell disorders to better understand these conditions. It mainly gathers information from patients who are confirmed to have one of several related diseases.
BeijingAges Any age - NCT05283759Recruiting
Brugada syndrome registry study at UZ Brussel
This study keeps a registry (a secure list) of people who have been diagnosed with Brugada syndrome. It helps doctors learn about the condition over time and may support future research aimed at better care.
BrusselsAges 18–100
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.