Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07364175Recruiting
Weight loss drug study for young adults with high blood pressure
This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
Cambridge, CambridgeshireAges 18–40 - NCT07370103Recruiting
Predicting low blood pressure in liver disease patients after anesthesia
This study uses an ultrasound to measure blood flow in the neck's main artery to see if it can predict a dangerous drop in blood pressure after you are put to sleep for surgery. It is for adult patients with chronic liver disease who are having planned surgery.
CairoAges 18 years+ - NCT07367633Recruiting
Head position after clot removal for stroke
This trial tests whether keeping the head of the bed flat or elevated after a mechanical clot-removal procedure affects recovery. It may help determine the best position to improve outcomes after a stroke caused by a large blockage in a brain artery.
Greater Sudbury, OntarioAges 18 years+ - NCT07363993Recruiting
Heart flow and pumping in athletes vs. non-athletes
This study uses 3D ultrasound to see how the heart moves blood in people who exercise a lot versus those who do not. It could help understand how regular endurance training changes heart function.
AvignonAges 18–45 - NCT07361887Recruiting
Moderate wine and healthy aging study
This study tests whether moderate wine consumption can help healthy aging by looking at tiny particles in your blood after a meal. It may help you understand how wine affects your body's cells.
Seville, SevillaAges 35–36 - NCT07362303Recruiting
Neuralert stroke monitor study for high-risk patients
This trial tests a device that monitors for stroke in adults who are at high risk after certain heart or blood vessel procedures. It could help detect a stroke early so you get treated faster.
Philadelphia, PennsylvaniaAges 22 years+ - NCT07369895RecruitingPhase 1
A new cell therapy for relapsed or refractory multiple myeloma
This trial tests a new cell therapy (O&D-001) for multiple myeloma that has returned or not responded to previous treatments. It targets specific markers on myeloma cells (BCMA or GPRC5D) and aims to shrink the cancer.
Guangzhou, GuangdongAges 18–75 - NCT07363161Recruiting
Drug-coated balloon vs. stent for high-risk heart disease
This trial compares two treatments for people with complex coronary artery disease who have high-risk conditions or complicated blockages: a drug-coated balloon (DCB) versus a drug-eluting stent (DES). Both are ways to open up narrowed arteries and keep them open without surgery.
HomburgAges 18 years+ - NCT07362446RecruitingPhase 2
Study of a heart drug for first-time heart attack patients
This trial tests a new drug given shortly after a first heart attack to see if it can reduce heart damage when blood flow is restored. It is for patients having a specific type of heart attack (STEMI) and getting a procedure to open the blocked artery within 6 hours of symptoms starting.
Kingswood, New South WalesAges 40–75 - NCT07367100Recruiting
Testing a new clot-removal catheter for stroke
This study tests a special catheter (a thin tube) designed to remove blood clots from large arteries in the brain during a stroke. The goal is to see if it is safe and effective at restoring blood flow.
EdegemAges 18–90 - NCT07368933Recruiting
A drug-coated balloon for heart artery blockages
This trial tests a balloon coated with two drugs to treat narrowed or re-narrowed arteries in the heart. It may help people with chest pain or recent mild heart attacks who need a procedure to open a blockage.
BarcelonaAges 18 years+ - NCT07368608RecruitingPhase 1/Phase 2
Testing a new drug for high blood pressure and cholesterol
This study tests a new medicine called BEBT-701 for people with mild to moderate high blood pressure and high cholesterol. The goal is to see if it can lower both blood pressure and LDL ('bad') cholesterol safely.
Changsha, HunanAges 18–60 - NCT07364630Recruiting
Placental membrane trial for diabetic and venous leg ulcers
This study tests whether a special wound dressing made from human placental membrane can help heal diabetic foot ulcers or venous leg ulcers that did not close with standard care. It is for people who were in the BIOCAMP trial and whose ulcer remained open after 12 weeks of standard treatment.
Philidelphia, PennsylvaniaAges 18 years+ - NCT04974151RecruitingPhase 4
Prevention trial for stroke risk in people with high blood pressure
This trial tests an approach to prevent first-time stroke and heart problems in people with high blood pressure who also have a specific genetic test result (MTHFR 677 TT). It may help by lowering risk before a first stroke happens.
Bengbu, AnhuiAges 45–74 - NCT06843616Recruiting
Study of a disposable brain clot removal scope for bleeding stroke
This study tests a new disposable tube with a camera (endoscope) that doctors use to remove a blood clot from the brain after a bleeding stroke. It is designed for people who are stable enough for surgery and whose bleed is in a part of the brain that is reachable with this tool.
Guiyang, GuizhouAges 18–80 - NCT04974138RecruitingPhase 4
Preventing first stroke in people with high-risk blood pressure
This trial tests whether a study medicine regimen can help prevent a first stroke in people with hard-to-control “high homocysteine” risk factors linked to a specific gene type. You may qualify if you have certain blood pressure levels, a specific MTHFR gene result, and related blood test findings.
Bengbu, AnhuiAges 45–74 - NCT05874206Recruiting
Branch stent graft for fixing aorta problems in the chest
This trial tests whether a “branch” stent graft can safely repair certain problems in the descending aorta (the big blood vessel in the chest). It may help by sealing the problem while keeping blood flow to an important branch vessel in the left upper chest area.
ZurichAges 18 years+ - NCT06387225Recruiting
Study on brain recovery after cardiac arrest
This study is trying to find better ways to predict recovery in people who had a cardiac arrest outside the hospital and are still unconscious in the intensive care unit. It may help doctors give more accurate information to families.
La Roche-sur-YonAges 18 years+ - NCT06842446Recruiting
Fast detection of blood clots using machine learning
This trial tests whether a machine learning algorithm can quickly detect deep vein thrombosis (blood clots) in people coming to the emergency room. It could help speed up diagnosis and treatment.
SarpsborgAges 18 years+ - NCT06846905Recruiting
Cost and effects of raising the dose of myeloma drugs at home vs. hospital
This study compares whether raising the dose of your current bispecific antibody is more cost-effective when done as an outpatient (day hospital) or as an inpatient. It aims to find the best way to manage your treatment safely.
ToulouseAges 18 years+ - NCT03206814Recruiting
Mobile app coaching to improve high blood pressure control
This trial tests whether a smartphone app with remote care (telecare) can help people with hard-to-control high blood pressure reach better blood pressure numbers. It may help you and your care team monitor progress more closely at home.
Bahía BlancaAges 18–80 - NCT05260125RecruitingPhase 4
Ultrasound-guided shoulder nerve block for stroke pain
This trial compares two ways to deliver a shoulder nerve block to relieve long-lasting shoulder pain after stroke: one guided by ultrasound and one without. It may help if your stroke-related shoulder pain has lasted at least a few months and you may benefit from a targeted pain-relief injection.
BoluAges 25–75 - NCT06068036Recruiting
Telehealth program to boost physical activity after stroke
This study tests whether a telehealth program with a wearable activity tracker can help people who have had a stroke become more active. It's designed for those who are ready to start moving more with their doctor's okay.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT06062017Recruiting
Potassium, hydration, and heart health in young adults
This study looks at how potassium and hydration affect heart and kidney health in healthy young adults. It may help you understand your own health and contribute to new knowledge about preventing disease.
Auburn, AlabamaAges 18–30
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.