Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07264166Enrolling by invitation
Gene therapy trial for cerebral palsy and HIE
This trial tests a gene therapy given as a nose spray for people with cerebral palsy or HIE. It aims to see if the treatment is safe and helps improve movement over two years.
Monterrey, Nuevo LeónAges 2–65 - NCT07259499Recruiting
Predictors of emergency visits in frail older adults
This study looks at why frail older adults go to the emergency room. Researchers want to see if blood tests and brain scans can help predict who needs emergency care. Participation involves one interview and having had a recent brain scan and blood work.
Pisa, PisaAges 65 years+ - NCT07260071Recruiting
High blood pressure in kids at risk for inherited kidney disease
This study looks for early signs of high blood pressure in children and teens (12–17) who have a parent with ADPKD, a kidney condition. It uses non-invasive tests like blood pressure monitoring and MRI to track kidney health.
LondonAges 12–17 - NCT07260032Recruiting
Exercise study for PTSD and heart health
This study tests if a supervised exercise program can improve heart health in people with PTSD. It may help reduce your risk of heart disease.
Boston, MassachusettsAges 18–65 - NCT07259733Recruiting
Fast control of tough high blood pressure in public clinics
This study tests a fast way to get high blood pressure under control faster for people whose current pills aren't working well enough. It focuses on people who have trouble taking all their medicine as directed (like missing doses).
São Paulo, São PauloAges 18–75 - NCT07260916Recruiting
Minimally invasive brain surgery for large hemorrhages
This trial tests a minimally invasive surgery to remove large, spontaneous brain hemorrhages soon after they occur. The goal is to see if this quick, targeted procedure can improve recovery compared with standard care.
Phoenix, ArizonaAges 18–80 - NCT07268859Recruiting
Fan to prevent ticagrelor-related shortness of breath
This study tests whether using a small fan can help reduce the shortness of breath (dyspnea) that some people feel when they first start taking the blood thinner ticagrelor after a heart attack.
Istanbul, AvcılarAges 18–65 - NCT07266675Recruiting
Recovery after cardiogenic shock study
This trial looks at what happens to people after they survive a serious heart condition called cardiogenic shock, where the heart suddenly can't pump enough blood. Researchers want to understand recovery and improve care for survivors.
TaipeiAges 18 years+ - NCT07263308RecruitingPhase 3
Albumin for large artery stroke after clot removal
This trial tests whether giving albumin, a protein naturally found in blood, can improve recovery after a large artery stroke when given along with a procedure to remove the clot. It's for people aged 18-80 who have a stroke from a blockage in the front part of the brain and can get treatment within 24 hours.
Anqing, AnhuiAges 18–80 - NCT07259577Recruiting
Vagus nerve stimulation for stroke recovery
This trial tests whether stimulating the vagus nerve can improve arm movement, breathing, and quality of life in people who had a stroke more than 6 months ago. It involves a non-invasive device that gently stimulates a nerve in the neck during therapy sessions.
Istanbul, IstanbulAges 18–70 - NCT07262580Enrolling by invitation
Finding meaning in cardiac rehab: a study
This study tests a program to help people in cardiac rehabilitation find personal meaning and purpose. It explores if the program works in individual, group, or paired sessions with a relative.
Odense, Region SyddanmarkAges 18 years+ - NCT07263490Recruiting
Pre-eclampsia Risk in Egg Recipients Study
This study looks at whether women who become pregnant after receiving donated eggs have a higher risk of developing pre-eclampsia (a serious blood pressure condition) during pregnancy. It aims to understand risks so doctors can better support pregnant women.
CopenhagenAges 18 years+ - NCT07268170Enrolling by invitationPhase 2/Phase 3
Heart rate control before heart CT scan
This trial tests two medicines to lower heart rate before a cardiac CT scan in adults who need the scan. It is for people whose heart rate is naturally a bit fast (over 65 beats per minute) but not too fast (under 100 bpm).
HerningAges 30–80 - NCT07268846Recruiting
Prebiotic supplement before colorectal cancer surgery
This trial tests if taking a postbiotic supplement before surgery for colorectal cancer can improve recovery. It may help patients with adenocarcinoma of the large intestine prepare for their operation.
São Paulo, São PauloAges 18 years+ - NCT07263204Recruiting
AI for diagnosing and predicting hypertrophic cardiomyopathy
This trial uses artificial intelligence to help diagnose and predict outcomes for people with hypertrophic cardiomyopathy (HCM), a condition where the heart muscle becomes thickened. It may help doctors better understand your condition and plan your care.
Hangzhou, ZhejiangAges 18 years+ - NCT07267468Recruiting
App and nutrition plan for swallowing recovery after stroke
This study tests a mobile health program combining rehabilitation exercises and a personal nutrition plan to help people recover from swallowing problems (dysphagia) after a stroke. The goal is to see if using the app improves swallowing and quality of life.
Algeciras, CadizAges 18 years+ - NCT07260474Recruiting
Closing a heart pocket to prevent strokes in atrial fibrillation
This study compares two similar devices that close off a small pocket in the heart to reduce stroke risk in people with atrial fibrillation who cannot take blood thinners safely. The goal is to see which device works better and is safer.
Fuencarral-El PardoAges 18 years+ - NCT07260656RecruitingEarly Phase 1
Capsaicin cream for diabetic nerve foot pain
This trial tests a new cream (Capsadyn®) made from chili pepper extract to see if it can reduce nerve pain in the feet caused by diabetes. If it works, it could offer a simple treatment you apply at home.
Roanoke, VirginiaAges 25–75 - NCT05442463Recruiting
Hormone effects on blood vessel narrowing in kidneys and arteries
This study looks at how hormone treatments (estrogen, progesterone, or testosterone) may affect how blood vessels tighten in the body, including in the kidneys. Researchers measure these effects to understand potential impacts on blood flow and blood vessel control.
Calgary, AlbertaAges 18–90 - NCT06758128Recruiting
Genes and immunity in worsening heart failure
This study looks at how your genes and immune system affect heart failure. Researchers want to understand why some people have flare-ups (exacerbations) and how the body responds.
San Giovanni Rotondo, FoggiaAges 18 years+ - NCT06812520Recruiting
Education to Help With Compression for Vein Ulcers
This study tests whether an educational program helps people with a grade 2 vein ulcer stick with compression treatment (bandages or stockings). It focuses on Spanish-speaking adults who have already started compression therapy.
Hualpén, BiobioAges 20 years+ - NCT06898307Recruiting
Genetic test study for inherited heart rhythm conditions
This study uses genetic testing to better diagnose, predict, and manage inherited heart rhythm diseases. It is designed for patients at the University of Ferrara's Cardiogenetic Center who have a confirmed genetic heart condition.
FerraraAges Any age - NCT06898762Recruiting
National study on inflammatory heart disease for patients with symptoms
This study is creating a national registry to learn more about inflammatory myocardial disease (inflammation of the heart muscle). If you have symptoms like chest pain, shortness of breath, palpitations, or certain test results, you may be eligible to join and help advance research.
Murcia, MurciaAges 18 years+ - NCT05899582Recruiting
Heart-bypass–like brain surgery for artery blockage patients
This trial studies whether a special bypass surgery can improve symptoms in people with a long-term (chronic) blockage of the middle brain artery. It aims to improve brain blood flow and reduce future stroke risk in the right patients.
BeijingAges 18–65
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.