Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05732701Recruiting
Personalized blood thinner plan after stent placement
This trial tests an algorithm (computer-guided plan) to choose the best “dual antiplatelet therapy” (two blood-thinning medicines) after a coronary stent. It aims to improve outcomes after the procedure while reducing avoidable problems from the medicines.
Banja LukaAges 18 years+ - NCT05732714Recruiting
Reduce heart event risk after major non-heart surgery
This study looks at ways to lower the chance of heart-related problems after major surgery that is not directly related to the heart. It focuses on people at higher heart risk who are expected to stay in the hospital for at least two days after surgery.
Toronto, OntarioAges 45–75 - NCT05733416Recruiting
FDG PET/CT scan after unexplained stroke to find hidden cancer
This study checks whether doing an intensive scan using FDG PET/CT shortly after a “cryptogenic” (unexplained) ischemic stroke can uncover an underlying cause, such as cancer. If a hidden source is found earlier, it may help guide the next treatment steps.
Ottawa, OntarioAges 18 years+ - NCT05733767RecruitingPhase 2
Nurse-led help to quit smoking after heart or lung illness
This Phase 2 study tests a nurse practitioner–led program and medicine plan to help you stop smoking after certain heart or lung conditions. It may help you quit and stay smoke-free, while using lab testing (like breath measurements) to confirm progress.
Springfield, MassachusettsAges 18 years+ - NCT05734378Recruiting
Study aims to predict outcomes in small blood vessel brain disease
This trial is looking at how brain “small blood vessel disease” changes over time and what outcomes to expect. If you have certain symptoms or scan findings from this condition, your care team may compare your prognosis to help guide future treatment planning.
BernAges 16 years+ - NCT05734404Recruiting
Long-term study of brain vessel inflammation
This study follows adults diagnosed with inflammation of blood vessels in the brain (CNS vasculitis). It aims to better understand the condition over time and could help improve how it’s diagnosed and managed.
Rochester, MinnesotaAges 18 years+ - NCT05735444Recruiting
CPAP registry for sleep apnea in people with high blood pressure
This study keeps a record of people with obstructive sleep apnea (OSA) who also have high blood pressure, to better understand how CPAP is used and what outcomes happen. It may help your care team by contributing your information to a large multi-center study in China.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05735639RecruitingPhase 4
Prevention of blood clots during varicose vein treatment
This trial tests whether giving medicine to prevent blood clots during varicose vein treatment is safe and helpful. It focuses on people having a minimally invasive procedure on enlarged leg veins under local anesthesia.
LondonAges 18 years+ - NCT05738083Recruiting
Study builds prediction tools after aneurysm bleeding
This study looks at early test results and brain scans to predict outcomes after an aneurysm causes subarachnoid hemorrhage. It mainly collects information to build a risk prediction model, which may help doctors plan care more effectively in the future.
Nanchang, JiangxiAges 18 years+ - NCT05737732Recruiting
Testing ambient light for multiple myeloma patients
This study looks at whether using a special kind of everyday light (called ambient light) can help people with multiple myeloma as they prepare for their first stem cell transplant. It may be aiming to improve comfort or recovery by affecting sleep and the body’s natural signals from light.
New York, New YorkAges 21 years+ - NCT05738603Recruiting
Predicting low blood pressure during head and neck flap surgery
This study looks at a way to predict low blood pressure during head and neck free flap surgery (when tissue is moved from one place to another). If successful, it may help the surgical team prevent complications by preparing earlier.
Poznan, PoznańAges 18 years+ - NCT05739253Recruiting
Study how the aorta changes after a valve procedure
This trial looks at how the ascending aorta (the main artery near the heart) changes over time after transcatheter aortic valve replacement. It may help doctors predict who is at risk of aorta enlargement after this less-invasive valve procedure.
Beijing, Beijing MunicipalityAges Any age - NCT05740579Recruiting
Storing eggs in teens with Turner syndrome variants
This study looks at freezing and storing eggs (cryopreservation) in children and teens with Turner syndrome or related genetic variants. It may help preserve the chance of having biological children later, if you are able to undergo the study procedures safely.
AarhusAges 2–17 - NCT05740735Recruiting
Testing sound-based brain signals to predict recovery after severe brain injury
This study checks how a brain responds to two kinds of sounds—neutral tones and emotional sounds—in people with a persistent disorder of consciousness after a serious event like stroke, head injury, or cardiac arrest. The goal is to see whether these brain “signal” tests can help doctors predict outcomes.
Paris, IDFAges 18 years+ - NCT05741593Recruiting
Interview study for older adults after ischemic stroke
This study talks with people age 65+ who were hospitalized for an ischemic stroke and are already on blood-thinning medicines to learn about their experiences. The interviews may help improve how pharmacists support patients after stroke.
VilleurbanneAges 65–100 - NCT05741905Recruiting
Levofloxacin antibiotic with IV clot-busting for acute stroke
This trial tests whether adding the antibiotic levofloxacin to standard IV clot-busting treatment is safe and improves outcomes after an acute ischemic stroke. It may help by reducing complications related to infection or inflammation, but you must meet specific heart, liver, kidney, and medication-safety rules.
Changchun, JilinAges 18–75 - NCT05742906Recruiting
Tricuspid valve repair using a new replacement valve patch
This trial studies a new valve replacement device (the Cor TRICUSPID ECM Valve) for people whose right-sided tricuspid valve is leaking or missing and needs surgery. It may help restore proper one-way blood flow in the heart, but you must meet several heart, blood, and organ-health requirements.
Indianapolis, IndianaAges Any age - NCT05743140Recruiting
Eye scan to help identify heart artery disease
This trial tests whether a special eye imaging scan (fundus OCTA) can help identify “CMD,” a type of heart-related blood flow problem. You may be eligible if you already had coronary angiography and your coronary narrowing is less than 50%.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05744219RecruitingPhase 3
Iron after major abdominal surgery to improve recovery
This Phase 3 study tests whether giving iron (as ferric carboxymaltose) after complex major surgery can improve recovery by helping your body rebuild blood and oxygen levels after blood loss. It may help patients who are having certain types of aortic, liver, or pancreas operations.
Uppsala, SverigeAges 18 years+ - NCT05746260Recruiting
Testing sleep timing to improve arm learning after stroke
This study looks at how sleep may affect how well people relearn arm movements after a stroke. If you’re within a month of a stroke that affected your arm, your participation could help researchers understand better ways to support recovery.
OxfordAges 18 years+ - NCT05746039RecruitingPhase 1/Phase 2
Testing semaglutide for advanced lung disease
This study checks whether semaglutide is safe and feasible for people with advanced lung diseases and higher body weight. It may help by testing a structured treatment approach, but it includes several health and safety limits.
Philadelphia, PennsylvaniaAges 18–80 - NCT05746221Recruiting
Study inflammation and brain small-vessel disease in adults 40+
This study looks at inflammation-related changes in people with “small-vessel disease” of the brain. It will follow participants over time to understand the condition better and see how brain symptoms may change.
NijmegenAges 40 years+ - NCT05746923Recruiting
Heart failure hospital registry for adults in Krakow area
This registry collects information from adults who were recently hospitalized for acute heart failure. It helps researchers better understand who is affected and how care is delivered after hospitalization.
KrakowAges 18 years+ - NCT05749094Recruiting
Ultrasound of the optic nerve in new suspected giant eye artery disease
This trial studies whether a quick ultrasound of the optic nerve (plus an eye exam) can help evaluate new suspected giant cell arteritis (GCA). It may help doctors assess eye risk early and decide on the best next steps.
London, OntarioAges 50–99
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.