Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT04102930Recruiting
Study of immune and genetic features in GCA and PMR
This study looks at immune system and genetic (inherited) differences in people diagnosed with giant cell arteritis or polymyalgia rheumatica. It aims to improve understanding of why these conditions happen and how they vary between people.
Canterbury, KentAges 50 years+ - NCT06025630RecruitingPhase 1/Phase 2
Testing TUDCA for blood pressure control
This study tests whether a supplement called TUDCA can help lower blood pressure by reducing stress inside cells. It's looking for people with high-normal blood pressure who are not on many heart medications.
Fort Worth, TexasAges 18–80 - NCT06715007Recruiting
Study on blood thinners and artery health for small vessel stroke
This study tests whether a combination of antiplatelet drugs and artery-stabilizing medication can improve recovery after a small stroke caused by damage to tiny blood vessels in the brain. It may help prevent further strokes and support healing.
Nanjing, JiangsuAges 30–79 - NCT06899867Recruiting
Comparing heart monitoring methods during liver transplant
This trial compares two ways to monitor how well your heart is pumping during liver transplant surgery. One method uses a thin tube in your blood vessels, and the other uses an ultrasound probe placed in your food pipe.
France, LyonAges 18 years+ - NCT06899399Recruiting
Stent study for asymptomatic carotid artery blockage
This trial tests a stent procedure to open a severely blocked carotid artery in people who have not had a stroke or mini-stroke from that blockage recently. It aims to see if the procedure is safe and effective for preventing future strokes.
BeijingAges 40–80 - NCT03594344Recruiting
Extra hyperbaric oxygen after leg amputation wounds heal
This study tests whether giving extra treatments with hyperbaric (pressure) oxygen after a leg amputation can improve healing or recovery. It’s meant for people whose amputation happened due to long-lasting infection or poor blood flow and who can attend follow-up visits.
OsloAges 18–90 - NCT06900270Recruiting
Comparing blood markers in coronary artery disease
This study looks at blood proteins and other molecules in people with different types of coronary artery disease. The goal is to see how these markers differ between those with blocked arteries, those with narrowed arteries, and those with no artery disease. This may help doctors better understand the disease and improve treatment.
São Paulo, São PauloAges 50–80 - NCT04442789Recruiting
Study of lasting effects after COVID-19 hospitalization
This study looks at what health problems remain after a person was hospitalized for COVID-19. It may help doctors understand these long-lasting effects and how to care for people afterward.
GiessenAges 18 years+ - NCT05327933Recruiting
Preventing chronic bleeding from the brain’s covering after surgery
This trial looks at whether a procedure called middle meningeal artery embolization can help stop chronic subdural hematoma (slow bleeding/collection under the brain covering) from coming back after your first surgery. It studies an added endovascular treatment right after your operation to reduce recurrence.
Berlin, State of BerlinAges 18 years+ - NCT05547165Recruiting
Closing a leaky heart connection early in very small babies
This trial compares an early procedure to close a heart vessel called the ductus arteriosus versus careful observation alone in very low-birth-weight preterm infants. It aims to see whether closing the vessel early can improve outcomes and be done safely.
Birmingham, AlabamaAges 1 week–1 month - NCT05521451Recruiting
Study for adults with heart rhythm problems
This trial is a “clinical cohort” study, meaning it follows adults with certain heart rhythm issues to understand them better. Your participation may help researchers learn what to expect and how best to support people over time.
HamburgAges 18 years+ - NCT05132387Recruiting
Out-of-hospital cardiac arrest registry using automatic CPR
This study records information about people who suffer an out-of-hospital cardiac arrest and receive automatic chest compressions. It focuses on specific heart rhythms and emergency timing, which may help improve future emergency treatment.
WroclawAges 18–60 - NCT05218278Recruiting
Nerve and brain signals after out-of-hospital cardiac arrest
This study looks at measurements taken after someone survives an out-of-hospital cardiac arrest to see if the results can predict outcomes. It may help doctors understand which patients are likely to do better and guide care in the ICU.
MariborAges 18 years+ - NCT05809310Recruiting
Stenting branches to improve blood flow after certain heart repairs
This study looks at whether placing a small tube (stent) in a branch pulmonary artery can improve blood flow and heart function after specific childhood heart surgeries. It is meant for people who have d-TGA after ASO, or have ToF or TA, and need a branch PA intervention.
AmsterdamAges 8 years+ - NCT06522750Recruiting
Periodic fasting for long COVID in adults
This study tests whether periodic fasting can help adults with long COVID. You may qualify if you are 18-64, have had COVID symptoms for at least 12 weeks, have a normal weight and low iron stores.
EttelbruckAges 18–64 - NCT07259278Recruiting
Heart rehab program with smart app support
This trial uses a smartphone app to guide exercise for people with coronary heart disease who are at low risk of complications. It aims to help you recover safely at home with remote support from doctors.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07254078Recruiting
Registry for chronic thromboembolic pulmonary hypertension patients
This study is a registry that collects information about people with chronic thromboembolic pulmonary hypertension (CTEPH). It helps doctors learn more about how this condition affects patients over time and how it is treated.
MoscowAges 18 years+ - NCT07254481RecruitingPhase 1
Safety study of VB19055 in healthy volunteers
This trial tests a new drug (VB19055) in healthy volunteers to see how safe it is and how the body processes it. Participants will be watched closely and may help find the right dose for future studies.
HangzhouAges 18–50 - NCT07255898RecruitingPhase 1
Study of BL-M24D1 for multiple myeloma and other blood cancers
This trial tests a new drug, BL-M24D1, for people with multiple myeloma or other blood cancers that have come back or not responded to standard treatments. It aims to see if the drug is safe and effective.
Chengdu, SichuanAges 18 years+ - NCT07258290Recruiting
Freesolve Magnesium Scaffold for Heart Artery Blockages
This trial tests a new dissolvable magnesium scaffold to treat blockages in heart arteries. It is designed for people with stable heart pain or certain recent heart attacks, and it aims to open blocked arteries and then slowly dissolve over time.
Washington D.C., District of ColumbiaAges 18–80 - NCT07258069Recruiting
Glue injection for chronic subdural hematoma
This trial tests whether injecting a medical glue into a specific artery in the brain can safely treat a chronic subdural hematoma (a collection of blood on the brain's surface) or a recurrent subdural hematoma. This approach may offer a less invasive alternative to traditional surgery.
Fukuoka, Kitakyushu-cityAges 18 years+ - NCT07254013Recruiting
LBBAP Pacemaker Monitoring with Portable ECG
This study is testing a portable heart monitoring device to help doctors check how well a special pacemaker (LBBAP) is working. It may help people who need a new or upgraded pacemaker or heart device.
Besançon, FranceAges 18 years+ - NCT07252531Recruiting
BrioVAD heart pump study for advanced heart failure
This trial tests a new heart pump (BrioVAD) for people with very advanced heart failure. It aims to help those who are not getting better with standard treatments or who need extra support like IV medicines or a balloon pump.
RotterdamAges 18 years+ - NCT07258511RecruitingPhase 3
Comparing a new drug to Teclistamab for advanced multiple myeloma
This study tests a new experimental drug (JNJ-79635322) compared to another targeted immunotherapy (Teclistamab) for people with multiple myeloma that has returned or not responded after several prior treatments.
Phoenix, ArizonaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.