Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05788120Recruiting
Study heart rhythm problems in adults on VA ECMO
This study looks at how often abnormal heart rhythms happen and how serious they are in adults who are supported with VA ECMO for severe heart failure. It mainly involves using medical information, aiming to better understand complications in this critical situation.
AngersAges 18 years+ - NCT05788770Recruiting
CT scan and computer planning before TAVR valve replacement
This study uses a CT scan plus a personalized computer model to plan a less invasive valve replacement (TAVR). It may help doctors better prepare for the procedure using simulation before your valve is placed.
ViennaAges 18 years+ - NCT05789303RecruitingPhase 2
Belantamab plus other medicines for relapsed multiple myeloma
This Phase 2 study tests whether belantamab mafodotin combined with carfilzomib, pomalidomide, and dexamethasone can better treat multiple myeloma that has come back. It may help people who have already tried other myeloma treatments but whose cancer has progressed again.
Chicago, IllinoisAges 18 years+ - NCT05789108Recruiting
Study of first leg blood clot and long-term effects
This study looks at people having their first blood clot in the leg and how it can affect them long-term. It may help doctors better predict complications and improve follow-up care after an emergency visit.
Hvidovre, CopenhagenAges 18 years+ - NCT05789823RecruitingPhase 2
Balloon post-treatment after clot removal in stroke
This trial tests whether a special balloon treatment started after successful clot removal can improve recovery after an acute stroke. It may help some people by protecting the brain during the procedure and early aftermath.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80 - NCT05791786Recruiting
Registry for suspected amniotic fluid embolism patients
This study builds a long-term registry and sample library for people diagnosed with suspected amniotic fluid embolism (AFE), and for certain related hospital deaths. It helps researchers understand what AFE looks like, how it affects health over time, and how to improve future care.
Houston, TexasAges Any age - NCT05793008Recruiting
Studying heart stress syndrome in sepsis using heart scans
This study looks at Takotsubo (also called stress cardiomyopathy) and heart problems caused by sepsis using specialized heart imaging (including PET). The goal is to better understand what triggers these conditions and how the heart is affected, which may improve diagnosis and care.
RomeAges 18 years+ - NCT05793177Recruiting
Monitoring light movement after stroke rehabilitation
This study checks whether tracking sitting time and light activity after stroke is helpful for recovery during rehabilitation. You would be monitored for daily movement, and the researchers want to see how activity patterns relate to recovery.
RoskildeAges Any age - NCT05794022Recruiting
Study of heart attack patients getting heart MRI
This study follows people 18 and older who have had a specific type of heart attack (STEMI). It aims to better understand them using a heart MRI scan, which may help improve how these patients are evaluated and cared for.
Bron, RhoneAges 18 years+ - NCT05794386Recruiting
Ablation plan guided by left-heart scar map for persistent atrial fibrillation
This study tests whether using a 3D heart “scar map” helps doctors choose a better catheter ablation strategy for people with persistent atrial fibrillation (AF). It may help reduce ongoing AF by targeting the scar area in the left atrium.
Seoul, Jongno-guAges 19 years+ - NCT05794399RecruitingPhase 4
Blood thinner after heart attack with clot seen on MRI
This trial tests how to use a blood thinner in people after a recent heart attack who have a clot in the left heart chamber confirmed by heart MRI. It may help lower the risk of the clot causing serious complications, but it also requires careful bleeding-safety screening.
Kathmandu, BagmatiAges 18 years+ - NCT05794464Recruiting
Safe tracking registry for people with Afib
This registry is collecting health information from people with atrial fibrillation (Afib) who are being considered for a procedure to restore normal rhythm. It aims to better understand safety and outcomes so future care can be improved.
Ostrava, Moravian-Silesian RegionAges 18 years+ - NCT05795842Recruiting
Detecting atrial fibrillation after stroke using a wrist monitor
This study checks whether a special wrist device can detect an irregular heartbeat (atrial fibrillation) in people who recently had a stroke with an unclear cause. It may help doctors find the cause earlier and tailor follow-up care.
Atlanta, GeorgiaAges 55 years+ - NCT05795686Recruiting
Study of the AVanCer day-center support program for patients
This study looks at how a day-center support program (AVanCer) affects patients and their caregivers. If you join, you may complete questionnaires and help researchers understand your experiences through assessments in French.
BronAges 18 years+ - NCT05797519Recruiting
Transcatheter valve replacement for leaking tricuspid valve
This trial studies a catheter-based procedure to replace the tricuspid valve in people with severe valve leakage. It aims to improve symptoms and heart function while tracking safety and effectiveness.
Sydney, New South WalesAges 18 years+ - NCT05797649Recruiting
Test a pleural fluid blood marker to tell heart failure vs others
This study checks whether a substance called NT-proBNP in pleural fluid can better identify if fluid around the lung is caused by heart failure. If you fit, the results may help doctors choose faster, more accurate diagnosis for your pleural effusion.
Hong Kong, New TerritoriesAges 18 years+ - NCT05799092Recruiting
Invasive vs non-invasive test for less-severe blocked heart arteries
This study compares two approaches to evaluating and treating people with symptoms of blocked heart arteries that are not “high-risk.” It may help doctors choose the safest, most effective next step for you by comparing invasive testing versus non-invasive evaluation.
Bucheon-siAges 19 years+ - NCT05800002Recruiting
IVUS-guided stent placement for badly calcified heart arteries
This trial studies a heart procedure that uses a special camera to guide where to place a drug-coated stent in an artery with heavy calcium. It may help improve how well the stent fits and works for people with certain types of coronary artery blockages.
Nanjing, JiangsuAges 18 years+ - NCT05799326Recruiting
Levofloxacin after sudden stroke to improve safety and recovery
This trial tests whether the antibiotic levofloxacin can be given soon after an acute ischemic stroke to improve outcomes and monitor side effects. It’s for people with a moderate stroke severity who are not having certain emergency treatments or infections.
Changchun, JilinAges 18–75 - NCT05800821Recruiting
Predicting brain blood-flow problems after carotid surgery
This study uses deep learning to predict which people are at risk for “cerebral hyperperfusion syndrome” (a dangerous spike in brain blood flow) after carotid revascularization. If you qualify, they’ll use scans/tests to estimate your risk so doctors can watch you more closely if needed.
MinskAges 30–80 - NCT05802121RecruitingEarly Phase 1
Testing a gut bacteria supplement side effects during prostate hormone therapy
This early-phase study looks at how changing gut bacteria (especially Akkermansia) affects metabolic side effects in men starting prostate hormone therapy (ADT). It may help researchers understand how to reduce or manage side effects for people on ADT.
London, OntarioAges 18 years+ - NCT05803564Recruiting
Stent placement study for a torn, bulging main artery
This trial tests a specialized stent (a small mesh tube) placed inside the chest and belly aorta to treat a thoracoabdominal aortic dissecting aneurysm. It may help prevent the artery from getting bigger or causing dangerous bleeding by supporting the weakened area from inside.
Beijing, Beijing MunicipalityAges 18–80 - NCT05802706Recruiting
Study of artery plaque tissue during surgery
This study looks at artery plaque tissue removed during a routine operation (endarterectomy) to better understand diseased vessel changes. You may be able to join if plaque tissue is part of your planned surgery and you can consent.
Limerick, LimerickAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.