Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05805137Recruiting
Bioimpedance monitoring for venous leg ulcers under compression
This study tests a skin-measurement method (bioimpedance) to monitor how venous leg ulcers heal while using standard compression therapy. It may help the study team track healing sooner and more accurately so treatment can be adjusted if needed.
TampereAges 18 years+ - NCT05806346Recruiting
TXA dosing for heart surgery patients on bypass
This trial studies whether giving tranexamic acid (TXA) based on patient needs during heart surgery works better than a one-size-fits-all approach. It may help reduce bleeding during surgery, while monitoring for clotting-related side effects.
SeoulAges 19 years+ - NCT05807841Recruiting
AI ultrasound during stent placement in heart artery blockages
This trial tests an artificial-intelligence tool that uses a heart ultrasound to help guide stent treatment. It may help doctors choose the best way to treat blockages and improve stent results for people with symptoms from reduced blood flow to the heart.
Bucheon-siAges 19 years+ - NCT05808686RecruitingPhase 2
Exercise-based training for circulation in older, frail adults
This study tests a special exercise training approach to help small blood vessels work better and improve resilience in frail older adults. If you join, you’ll do training that may involve temporary blood-flow restriction, so safety rules are important.
Wauwatosa, WisconsinAges 65–85 - NCT05809323Recruiting
Trial testing moderate exercise in teens with Marfan syndrome
This trial studies whether doing moderate exercise is safe and helpful for people with Marfan syndrome. It aims to see how exercise affects heart and health measures, like how the aorta and body respond over time.
Houston, TexasAges 10–25 - NCT05809310Recruiting
Stenting branches to improve blood flow after certain heart repairs
This study looks at whether placing a small tube (stent) in a branch pulmonary artery can improve blood flow and heart function after specific childhood heart surgeries. It is meant for people who have d-TGA after ASO, or have ToF or TA, and need a branch PA intervention.
AmsterdamAges 8 years+ - NCT05809856Recruiting
Check if a patient’s own valve tissue can be safely used
This study tests whether a new type of heart valve made from your own tissue (an “autologous” valve) can be placed through a catheter safely in adults with leaking and pressure-related problems in the lung heart valve area. If it works well, it could offer a safer option for people who need treatment for pulmonary valve problems.
Berlin, State of BerlinAges 18–80 - NCT05811364Recruiting
Stent versus bare-metal treatment for blocked leg arteries
This study compares a new balloon-expandable stent to standard bare-metal stenting to treat complex blockages in the iliac arteries (main blood vessels to the legs). It may help people with symptoms like leg pain with walking, pain at rest, or minor tissue injury by improving blood flow and reducing repeat procedures.
Little Rock, ArkansasAges 18 years+ - NCT05811780Recruiting
Record of devices that support organs outside the body
This registry collects information about people who are treated with a machine that supports an organ outside the body. The goal is to better understand how these devices are used and may help improve care over time.
Freiburg im BreisgauAges Any age - NCT05812963Recruiting
IVUS vs FFR to guide stents after heart attacks
This trial compares two ways of measuring blood flow inside the heart arteries (IVUS vs FFR) to help decide which non–culprit artery narrowings need a stent after a recent heart attack. It may help doctors choose the best targets for PCI and avoid unnecessary procedures.
GwangjuAges 19 years+ - NCT05817305Recruiting
Exercise program for people with past heart problems
This trial looks at adding regular exercise to everyday life for people who have had previous heart events. It aims to improve safety and day-to-day health by monitoring who can exercise safely.
Ferrara, FerraraAges 18 years+ - NCT05817851RecruitingPhase 2
Vitamin C by vein after cardiac arrest shock
This Phase 2 study tests whether early high-dose vitamin C given through a vein can improve outcomes for people who remain unconscious after an out-of-hospital cardiac arrest with shock. It may help by supporting recovery during the time when the body is under severe stress.
AmiensAges 18 years+ - NCT05818605Recruiting
Exercise training for people with hypertrophic heart muscle
This study tests whether a 24-week exercise program can improve exercise tolerance in people with hypertrophic cardiomyopathy (a thickened heart muscle). You may be asked to use phone-based tools and complete surveys during training.
San Francisco, CaliforniaAges 18–80 - NCT05819008Recruiting
Online brain testing for people with neurological conditions
This trial studies how well a remote, online memory and thinking assessment works for people with neurological disorders or injuries. You may be invited if you can do the computer-based testing and speak Swedish.
UmeåAges 18 years+ - NCT05820815Recruiting
In-bed exercises for early recovery after stroke
This trial tests whether a simple exercise program done in bed is safe and practical for people in the first few months after a stroke. It may help you start gentle lower-leg movement without needing to get fully out of bed right away.
Seoul, JongnoAges 19 years+ - NCT05820516Recruiting
Study of a valve treatment for severe leaking tricuspid valve
This trial looks at a catheter-based procedure using the TricValve system for people with severe “tricuspid regurgitation” (a leaky tricuspid valve) who are very symptomatic. It may help reduce the backflow and improve heart function, especially for people who are too unwell for or not helped by standard options.
Pisa, PisaAges 18 years+ - NCT05821894Recruiting
Imaging study of plaque in neck arteries before surgery
This study uses pictures (imaging) to learn more about plaque in the neck arteries in people who are being considered for carotid endarterectomy. The results may help doctors better understand artery plaque and improve care.
Malmö, Skåne CountyAges 18 years+ - NCT05823519Recruiting
Follow-up study after Ovation repair for abdominal aneurysm
This trial studies people who need an endovascular repair for a type of abdominal aortic aneurysm using the Ovation Alto device. It looks at outcomes after treatment and shares study data with the research team, which may help improve care for future patients.
Palma de Mallorca, Balearic IslandsAges 18 years+ - NCT05824520Recruiting
CT blood-flow test guided treatment versus usual care
This trial compares a treatment plan guided by a special CT scan measurement of blood flow (called CT-derived FFR) versus standard medical therapy. It may help doctors choose the safest, most effective treatment based on how restricted blood flow looks on CT.
Hangzhou, ZhejiangAges 18 years+ - NCT05825911Recruiting
Magnetocardiography test for suspected heart artery disease
This trial checks how accurate a magnetocardiography (MCG) scan is in people who are being evaluated for possible coronary artery disease. It may help doctors choose better diagnostic tests by comparing the scan results to the standard evaluation you are already getting.
Seoul, Eunpyeong-guAges 19–80 - NCT05826665Recruiting
Study of heart rhythm mapping during AF ablation
This is an observational study that looks at how a special heart mapping system may affect the procedure and outcomes for people having ablation for persistent atrial fibrillation (AF). It may help doctors better understand what works best and how procedures turn out.
Jonesboro, ArkansasAges 18–80 - NCT05826548Recruiting
Telerehabilitation program for memory, Parkinson’s, and stroke needs
This trial studies a home-based exercise and training program delivered by telerehabilitation (remote care) for people with mild cognitive impairment, Parkinson’s disease, or stroke. It may help improve day-to-day thinking and movement skills by supporting you with structured practice from home.
Lido, VeneziaAges 18–85 - NCT05826925Recruiting
Care planning for women after pregnancy-related high blood pressure
This study tests ways to improve cardiovascular (heart and blood vessel) care for women after they had high blood pressure during pregnancy. It may help you get better guidance to prevent future heart problems.
Salt Lake City, UtahAges 18 years+ - NCT05828511RecruitingPhase 1/Phase 2
Study drug for newly diagnosed myeloma before standard treatment
This trial tests linvoseltamab (a new targeted immune treatment) to see if it’s safe and how well it works in adults with recently diagnosed multiple myeloma who haven’t started treatment yet. Because it’s a “window of opportunity” study, it’s meant to learn early results before standard therapy is fully underway.
Los Angeles, CaliforniaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.