Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT06467825Recruiting
Sex differences in standing up after moon landing
This NASA trial tests how men and women differ in standing up after landing on the moon. Volunteers receive a water pill (furosemide) to see how their blood pressure and heart respond during simulated lunar descent and ascent.
Houston, TexasAges 25–55 - NCT06065124Recruiting
Study on weight loss surgery for heart failure with irregular heartbeat
This trial tests if weight loss surgery can help people with heart failure and atrial fibrillation (an irregular heartbeat) improve their heart condition. You may join if you are between 45 and 70, have a BMI of 32 to 40, and have mild to moderate heart failure with preserved pumping function.
Arnhem, GelderlandAges 45–70 - NCT06706323Recruiting
Depression after heart surgery study
This study looks at depressive symptoms in people who have had heart bypass surgery. It aims to understand how patients feel emotionally after surgery and may help improve care.
ZurichAges 18–90 - NCT07242326Enrolling by invitation
Blood Thinner Dose Check for Older Adults With AFib
This study looks at whether older adults with atrial fibrillation are taking the right dose of their blood thinner medicine. It aims to improve how doctors prescribe these medications in primary care.
Ordu, OrduAges 65 years+ - NCT07240714Enrolling by invitation
Web-based support for cardiac arrest survivors
This study tests a web-based support program for people who have survived a cardiac arrest. It aims to help you with recovery by providing online tools and information.
GothenburgAges 18 years+ - NCT07241429Recruiting
Fear of movement and balance after stroke
This study looks at how fear of movement (kinesiophobia) affects balance in people who have had a stroke. It may help understand how to improve recovery.
IstanbulAges 18–80 - NCT07246577Recruiting
Improving diagnosis and monitoring in giant cell arteritis
This study uses ultrasound, a biopsy of the temple artery, and blood tests to improve how giant cell arteritis (GCA) is diagnosed, monitored, and predicted. It may help doctors find better ways to manage this condition.
GothenburgAges 18 years+ - NCT07245927Recruiting
Staphylokinase for massive pulmonary embolism with shock
This trial tests a single injection of a clot-busting drug called staphylokinase for people with a massive pulmonary embolism that is causing shock or very low blood pressure. It aims to see how well the drug works in this emergency situation.
BelgorodAges 18 years+ - NCT07247032Recruiting
Heart failure management with remote monitoring
This trial tests whether remote monitoring of your implanted heart device can help your doctors better manage your heart failure. It is for people with certain types of pacemakers or defibrillators who are willing to share their device data remotely.
ParisAges 18–85 - NCT07248176Recruiting
Universal CAR-T therapy for multiple myeloma
This trial tests a universal CAR-T cell therapy (made from donated cells) for multiple myeloma that has come back after at least two prior treatments. It may be an option if your cancer cells have a specific marker called BCMA and you have not had certain prior therapies.
ShanghaiAges 18 years+ - NCT07241390RecruitingPhase 3
Study of orforglipron for heart and kidney health.
This trial tests if orforglipron can reduce the risk of heart attack, stroke, or kidney failure in people with heart disease or chronic kidney disease.
Bahía BlancaAges 50 years+ - NCT07241520RecruitingPhase 3
Testing SHPL-49 injection for recent stroke patients
This trial tests a new medication, SHPL-49, given as an injection to people who have just had a stroke caused by a blood clot (ischemic stroke). It is for patients who are already receiving standard clot-busting treatment within 8 hours of symptoms starting. The study will see if adding this drug helps improve recovery.
Linfen, ShanxiAges 18–80 - NCT07241104RecruitingPhase 1
Study of a new drug for dilated cardiomyopathy with a specific genetic change
This trial tests an experimental drug called AZD4063 for people with dilated cardiomyopathy caused by a specific genetic mutation (R14del in the PLN gene). The goal is to see if the drug can improve heart function and symptoms.
AmsterdamAges 18–80 - NCT07243184Recruiting
Polymer heart valve study for mitral valve disease
This trial is testing a new polymer artificial heart valve for people with severe mitral valve problems. It aims to see if this valve is safe and works well during surgical replacement.
BeijingAges 60 years+ - NCT06190210Recruiting
Brain blood flow study in infants with heart defects
This study measures how well blood flows to the brain in infants with serious heart defects. The results may help doctors understand and protect brain development before and after heart surgery.
Leuven, Vlaams-BrabantAges Up to 6 months - NCT07244484Recruiting
Brain Training for Heart Health in Coronary Artery Disease with Anxiety
This trial tests a brain training technique (neurofeedback) to help people with coronary artery disease and anxiety. It aims to improve heart rate control by targeting a specific brain area.
Shenyang, LiaoningAges 18 years+ - NCT07245264RecruitingPhase 2/Phase 3
TXA for preventing return of subdural hematoma
This trial is testing whether giving a medicine called tranexamic acid (TXA) during surgery helps prevent rebleeding after draining a chronic subdural hematoma. TXA helps stop bleeding, and the goal is to reduce the chance the hematoma comes back.
ChandigarhAges 18 years+ - NCT07247058RecruitingPhase 4
Testing Isturisa for mild cortisol excess from adrenal tumors
This study tests whether a drug called Isturisa (osilodrostat) can safely lower mild cortisol excess in people with adrenal tumors. It aims to help patients avoid the long-term effects of too much cortisol.
Baltimore, MarylandAges 18 years+ - NCT07245082Recruiting
Type 2 diabetes patient study
This study looks at people with type 2 diabetes to understand their health. If you join, you'll have simple measurements taken like height, weight, and grip strength.
Taipei, Zhongzheng DistAges 18 years+ - NCT07246473Recruiting
Non-invasive ultrasound for brain bleed clearance
This trial tests a non-invasive ultrasound device to help clear blood clots from the brain after a spontaneous bleed. It may be an option for people with small to medium-sized bleeds who do not need surgery.
Wuhu, AnhuiAges 18–80 - NCT07247669Recruiting
AI phone triage for emergencies
This study tests if artificial intelligence can help identify time-sensitive emergencies like stroke, heart attack, or trouble breathing from recorded phone calls. The goal is to make emergency response faster and more accurate.
Málaga, MálagaAges Any age - NCT07248618Recruiting
Balance and trunk training for stroke recovery
This study compares two types of physical therapy exercises to see which one better helps stroke survivors improve trunk control, balance, and daily activities. It may be a good fit if you had an ischemic stroke and are between 6 months and 1.5 years into recovery.
Lahore, Punjab ProvinceAges 40–75 - NCT07243704RecruitingPhase 3
Antiplatelet medicine to prevent heart events after brain bleed
This trial tests whether a common antiplatelet medicine can reduce the risk of future heart attacks, strokes, or blood clots in people who have had a brain bleed. It's for adults who had their first brain bleed and can start treatment within 3 months of the stroke.
Guntur, Andhra PradeshAges 18–99 - NCT07243080RecruitingPhase 4
Blood thinner comparison to prevent clots after belly surgery
This trial compares two blood thinners, Rivaroxaban (a pill) and Enoxaparin (a shot), to see which works better at preventing dangerous blood clots in the legs after emergency abdominal surgery. It may help you if you need to stay in bed for more than a day after your operation.
Lahore, Punjab ProvinceAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.