Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05777447Recruiting
Study for infected aorta/iliac aneurysm after in-place repair
This study looks at treatment outcomes for people whose aorta or iliac artery aneurysm became infected (a “mycotic” aneurysm) and who were treated with an in-place repair. It may help doctors understand the best way to manage this rare condition after surgery.
Roma, RMAges 18 years+ - NCT05777551Recruiting
High-power short treatment for irregular heartbeat
This trial studies a specific heart-rhythm procedure that uses higher power for a shorter time to treat atrial fibrillation (AF), an irregular heartbeat. It may help some people control AF and reduce rhythm episodes, while doctors compare outcomes using their chosen approach.
ParisAges 18–80 - NCT05778188RecruitingPhase 2
RLS-0071 for newborns with moderate or severe HIE
This trial studies whether RLS-0071 is safe and can help some newborns with moderate or severe hypoxic-ischemic encephalopathy (HIE), a brain injury caused by low oxygen around birth. Babies in the study also receive standard whole-body cooling (therapeutic hypothermia), and the researchers will watch for side effects and early signs of benefit.
Little Rock, ArkansasAges Up to 10 hours - NCT05777681Recruiting
Treating infection in the aorta or iliac arteries
This trial studies a surgical product made from animal tissue to treat infections involving the aorta and nearby blood vessels. It may help people whose grafts or weak spots (aneurysms) are infected.
RomeAges 18 years+ - NCT05777655Recruiting
Medication app to help people take statins as prescribed
This trial studies whether a medication-management phone app can improve how reliably you take a high-intensity statin (cholesterol-lowering medicine). You may be eligible if you’re starting a statin for blood vessel disease and have higher LDL (“bad cholesterol”) levels.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT05778981Recruiting
Study of blood-vessel health during non-heart surgery
This study looks at how blood-vessel function changes around the time of non-heart surgery, especially in people 45 and older. It may help doctors better understand risks and recovery related to blood-vessel stress during hospitalization.
Independencia, Santiago MetropolitanAges 45 years+ - NCT05779215Recruiting
Registry for acute stroke with blocked brain arteries
This study records information about people who have a new acute ischemic stroke caused by a blockage in a larger or medium-sized brain artery. It may help doctors better understand outcomes and care for this stroke type, using data from many patients.
Beijing, Beijing MunicipalityAges Any age - NCT05778773Recruiting
Study of treatment outcomes for severe aortic valve narrowing
This study looks at how well current treatment choices work for older adults with severe aortic valve narrowing (stenosis). It may help doctors better understand what works best for aging patients in Italy.
San Donato Milanese, MIAges 65 years+ - NCT05779787Recruiting
Registry after aortic valve procedure to guide future care
This registry is for people with severe, symptomatic aortic valve narrowing who are planning a TAVI procedure (a less invasive valve replacement). It aims to better track and improve how patients do after the valve is replaced, based on how the procedure is planned and performed.
Milan, LombardyAges 18 years+ - NCT05780359Recruiting
Testing a drug-coated stent for leg artery blockages
This study tests whether a special “drug-eluting” stent placed in a leg artery works safely and improves blood flow for people with peripheral artery disease. It may help reduce re-narrowing and improve walking, depending on your blockage details and overall health.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05780034RecruitingPhase 1
Study drug AC676 for certain relapsed blood cancers
This Phase 1 trial tests AC676, a study medicine, for adults with certain B-cell blood cancers that have come back or did not respond to prior treatment. It may help people who have tried standard therapies and need new options.
Denver, ColoradoAges 18 years+ - NCT05780099Recruiting
Study of patients treated in internal medicine clinics
This observational study follows people receiving care in Internal Medicine at San Raffaele Hospital to better understand what kinds of conditions they have. It does not test a new treatment, but your information may help improve future care.
MilanAges 18 years+ - NCT05780710Recruiting
Smartphone blood pressure monitor tested for people with high BP
This study compares an optical blood pressure monitor (used like a home device with a smartphone) against standard home blood pressure readings. It’s meant to see if the new device gives accurate results for people with high blood pressure who are not currently on blood pressure medicines.
Geneva, Canton of GenevaAges 21–85 - NCT05780905RecruitingPhase 4
Semaglutide study for brain blood flow in type 2 diabetes
This trial tests whether semaglutide changes blood flow in the brain and the brain’s “barrier” (how well the brain is protected) in people with type 2 diabetes. It may help researchers understand brain-related effects of diabetes treatment using scans and blood tests.
Seattle, WashingtonAges 40–65 - NCT05782010Recruiting
Testing a hemorrhoid device for grade II or III hemorrhoids
This study tests how safe and well a hemorrhoid treatment device (PexyEazy®) works for adults with moderate-to-severe hemorrhoids (grade II–III). You may be a candidate if you fit the hemorrhoid grade and medical safety requirements and can follow the study plan.
FrölundaAges 18–84 - NCT05782582Recruiting
Testing care for long-term heart artery symptoms in primary care
This study looks at people who come to primary care with symptoms that may be caused by long-term narrowing of heart arteries. The goal is to test an approach for identifying and managing this condition earlier or more accurately in everyday care.
LinköpingAges 18 years+ - NCT05782556Recruiting
Freiburg TIPS Registry for portal hypertension patients
This is a registry study that collects information from people who need a procedure called TIPS for portal hypertension. It may help doctors better understand outcomes and care for both cirrhotic and non-cirrhotic causes of portal hypertension.
Freiburg im BreisgauAges 18–100 - NCT05783375Recruiting
Rheumatic heart prevention program for Ugandan communities
This study helps deliver prevention care for rheumatic heart disease in specific districts of northern Uganda. If you live there (or provide care in the selected clinics), the program may offer extra support to help stop heart damage before it starts.
Kampala, UgandaAges 5 years+ - NCT05785156Recruiting
Quick test study to predict stroke and memory disease outlook
This study tests quick new methods to measure “slowed actions” in people with stroke or memory-related brain conditions. The goal is to see whether these quick tests can help predict future outcomes and guide care.
AmiensAges 40–85 - NCT05785897Recruiting
Stent without polymer plus aspirin-like therapy for heart attack
This trial studies whether a specific stent (with no polymer coating) plus a single blood thinner plan with aspirin and another P2Y12 medicine is as safe and effective as the standard two-medicine plan after a STEMI heart attack. It may help people avoid longer exposure to stronger blood-thinning if the new approach works as well.
Geneva, Canton of GenevaAges 18 years+ - NCT05786001Recruiting
Test noninvasive checks of blood flow in limb-threatening ischemia
This study uses painless, noninvasive tests to measure blood flow in people with chronic limb-threatening ischemia. It may help doctors better understand circulation problems and track blood flow without procedures.
Tampere, PirkanmaaAges 18 years+ - NCT05786131Recruiting
Stent treatment: fix all blocked arteries vs culprit only
This trial compares two ways of doing a stent procedure in people who had an NSTEMI heart attack: fixing all significant blockages versus fixing only the “culprit” blockage. It may help find which approach is safer and more effective for preventing complications.
GrazAges 18 years+ - NCT05786417RecruitingPhase 4
Medication comparison for older adults with stable heart pain
This trial tests which heart medications work best for older adults who have stable angina (predictable chest pain) and multiple other long-term health problems. You may be asked to start or adjust medications and attend regular follow-up visits to see which approach controls symptoms and outcomes.
New Haven, ConnecticutAges 65 years+ - NCT05788666Recruiting
GeriKit check-up for older adults after heart artery problems
This trial tests a “GeriKit” set of questions and measurements to better understand health and needs in people age 75+ after a heart attack or related procedures. It may help doctors plan more personalized care during recovery.
New York, New YorkAges 75–100
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.