Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07230847Recruiting
Healing of drug-coated vs. standard stents in high-bleeding-risk patients
This trial compares two types of stents (a drug-coated stent and a standard drug-eluting stent) in people with acute coronary syndrome who also have a high risk of bleeding. It uses a special camera to look at how the artery heals one month after the stent is placed.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07239323RecruitingPhase 1
CAR-T therapy for blood cancers that have returned or not responded
This trial tests a new CAR-T cell therapy for people with certain blood cancers (B-cell acute lymphoblastic leukemia, B-cell lymphoma, or multiple myeloma) that have come back or stopped responding to treatment. The therapy uses your own immune cells, modified in a lab to attack cancer cells, then given back to you intravenously.
Kunming, YunnanAges 18 years+ - NCT07231757Recruiting
Blood pressure study for older adults
This study tests a treatment to lower blood pressure in adults aged 65 and older whose blood pressure is not well controlled with their current medications. It may be an option for those looking for additional ways to manage their hypertension.
Detroit, MichiganAges 65 years+ - NCT07236801RecruitingPhase 1
Cell therapy for hard-to-treat autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with several autoimmune diseases that have not improved with standard medications. It aims to see if this treatment can help control the disease when other treatments have failed.
Xuzhou, JiangsuAges 18–65 - NCT07236762RecruitingPhase 1
YTS109 cell therapy for severe autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with severe autoimmune diseases like lupus, Sjögren's syndrome, systemic sclerosis, inflammatory myopathy, vasculitis, and antiphospholipid syndrome. It's for those whose disease hasn't improved with standard treatments.
BengbuAges 18–65 - NCT07230964Recruiting
Heart valve study using a non-invasive skin test
This trial tests a special skin test (impedance cardiography) that may detect heart muscle changes in people with aortic stenosis. It could help doctors decide when valve replacement is needed.
Chicago, IllinoisAges 18 years+ - NCT07234032RecruitingPhase 3
Long-term follow-up study of TPIP for PH-ILD
This trial is a long-term follow-up study for people who already completed a previous study of an inhaled treprostinil medication (TPIP) for pulmonary hypertension caused by interstitial lung disease (PH-ILD). It tests whether continued treatment with TPIP is safe and effective over a longer period.
Naples, FloridaAges 18 years+ - NCT07235462Recruiting
Acoramidis for heart disease due to TTR amyloidosis
This study follows people with a heart condition called transthyretin amyloid cardiomyopathy (ATTR-CM) who are starting treatment with acoramidis. It aims to see how well the medicine works in everyday medical practice.
Multiple LocationsAges 18 years+ - NCT06311461Recruiting
Acupuncture for stable chest pain
This trial tests whether acupuncture can help relieve symptoms of stable angina, a type of chest pain that happens when your heart isn't getting enough blood. If you have chest pain at least once a week and are already on heart medications, you may be able to join.
Los Angeles, CaliforniaAges 21 years+ - NCT06325384Recruiting
Testing a contactless blood pressure monitor for home use
This trial tests a new, no-contact device called Lifelight that measures your blood pressure just by looking at your face. It compares these readings to the standard cuff method, and you can use it at home for self-monitoring.
LondonAges 18–100 - NCT06567626Recruiting
Decision aid for heart artery treatment choices
This study is testing a new tool to help patients and doctors decide together on the best procedure (like stents or bypass surgery) for blocked heart arteries. It aims to make the decision process clearer and more personalized.
LeicesterAges Any age - NCT06755840Recruiting
Sleep breathing problems and multiple health conditions study
This study is for people who may have sleep-related breathing problems (like sleep apnea). It looks at how these issues connect with other health conditions. Participants will do a one-night sleep test and some simple health checks at Xiangya Hospital.
ChangshaAges Any age - NCT07232498Recruiting
Early ultrasound-guided movement after a stroke
This trial tests if starting supervised mobility early (within 48 hours) using Doppler ultrasound to guide care can help recovery in adults who just had a stroke caused by a clot. It may help you avoid complications and regain function sooner.
RijekaAges 18 years+ - NCT07236398Enrolling by invitation
Modified left atrial maze procedure for atrial fibrillation
This trial tests a modified maze procedure to treat atrial fibrillation during heart surgery. It may help patients with AFib who are already scheduled for cardiac surgery.
Toulouse, French (France)Ages 18 years+ - NCT07231172Recruiting
Fatigue after stroke and its link to clinical factors
This study examines how fatigue affects people who have had a stroke, looking at physical and mental health factors. It may help understand why some people feel more tired than others after a stroke.
AnkaraAges 18 years+ - NCT07236125Recruiting
Nitrate-rich foods and mouth bacteria in children with high blood pressure
This study looks at how eating nitrate-rich vegetables (like spinach and beets) might affect the helpful bacteria in your child's mouth and their blood pressure. It's for children ages 10 to 18 who have primary hypertension (high blood pressure not caused by another condition) and are otherwise healthy.
Istanbul, FatihAges 10–18 - NCT07232017Recruiting
Intensive blood pressure management study at Cleveland Clinic
This trial tests a program to help people with high blood pressure get it under better control. If you have high blood pressure that is not well-managed, this study may offer extra support and monitoring.
Cleveland, OhioAges 18–85 - NCT07236021Recruiting
e-Motion: emotion support for chronic cancer patients
This trial tests an online program called e-Motion that helps people with chronic cancer manage their emotions. It may help you feel more in control and better cope with your diagnosis and treatment.
Brussels, AnderlechtAges 18 years+ - NCT07238920Recruiting
Brain training for heart health in people with coronary artery disease and anxiety
This trial tests a brain-training technique called neurofeedback, which uses a video game controlled by your brain activity to help your heart and nervous system work better. It is for people with both coronary artery disease and anxiety who want to improve their heart health and manage anxiety without medication.
Shenyang, LiaoningAges 18 years+ - NCT07236970Recruiting
AI screening for pulmonary hypertension in scleroderma
This study uses artificial intelligence to find better ways to screen for pulmonary arterial hypertension (a type of high blood pressure in the lungs) in people with systemic sclerosis (scleroderma). The goal is to catch the condition earlier so treatment can start sooner.
Granada, AndalusiaAges 18–80 - NCT07232277Recruiting
Vein congestion and kidney injury after heart surgery
This trial looks at how fluid buildup in veins might relate to kidney injury after planned heart surgery. It aims to find ways to prevent kidney damage. Participants must be having planned (non-emergency) heart surgery, be 18 or older, and have healthy kidneys and overall health.
Yangzhou, JiangsuAges 18 years+ - NCT07236879Recruiting
AI eye test for diabetes patients in primary care
This trial uses an artificial intelligence (AI) system to check for diabetic eye disease (retinopathy) during your regular doctor visit. It aims to detect problems early so you can get treatment sooner.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07237386Recruiting
Testing a smart insole for walking in people with brain or spinal cord injury
This study tests a special insole that measures how you walk, compared with a high-tech walking lab. It's for people with stroke, spinal cord injury, or brain injury who can walk on their own for 6 minutes.
GhentAges Any age - NCT07231939Recruiting
Testing diabetes drugs to protect kidneys after heart procedures
This study is testing whether a class of diabetes medicines called SGLT2 inhibitors (specifically empagliflozin or dapagliflozin) can prevent kidney injury after heart procedures that use contrast dye.
BydgoszczAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.