Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05866003Recruiting
Brain stimulation plus hand training after stroke
This trial tests whether a combination of brain stimulation and structured hand practice can improve hand movement for people recovering from stroke. It may help because the training targets upper-limb function while using therapy intended to support recovery.
Cleveland, OhioAges 21–90 - NCT05866757Recruiting
Stopping maintenance treatment in multiple myeloma patients
This study looks at whether it is safe to stop “maintenance” treatment for people with multiple myeloma who have been in remission for a long time, including those who stopped early because of side effects. It tests whether stopping therapy affects disease control and helps reduce ongoing treatment burden.
Cork, IrelandAges 18 years+ - NCT05866640RecruitingEarly Phase 1
Testing a filter to reduce debris during TAVR
This early feasibility study tests a device filter system used during a TAVR procedure to help protect the brain and other organs from debris that can break free. It looks mainly at whether the filter can be safely placed and delivered as planned.
TbilisiAges 22 years+ - NCT05866874Recruiting
Watching heart warning signs after non-heart surgery
This study checks whether close monitoring of vital signs around the time of non-cardiac surgery can help identify small heart injuries (called perioperative myocardial infarction or injury). It may help doctors spot people at higher risk sooner, especially after certain major surgeries.
Basel, Canton of Basel-CityAges 40–85 - NCT05867433Recruiting
Teens club to improve school food and activity
This trial helps 6th and 7th graders join a school “change club” to improve healthier food and more physical activity at school. It’s mainly for students in participating Title 1 middle schools and who meet the school and student rules.
Dallas, TexasAges 8 years+ - NCT05867381Recruiting
Air purifier use to slow heart artery plaque in older adults
This trial tests whether using indoor air filtration at home can slow the progression of heart artery plaque-related problems in people with a past history of ischemic heart disease. It may help by improving indoor air quality, which the study links to inflammation in the body.
Los Angeles, CaliforniaAges 65–84 - NCT05868161Recruiting
Registry for patients treated with a thrombectomy device
This registry collects past treatment information from people who had a clot procedure using the Pounce Thrombectomy System. It helps researchers understand how this device is used in real-world care and what outcomes may look like.
Peoria, IllinoisAges 18 years+ - NCT05868239Recruiting
Testing an aerosol box during CPR emergencies
This study tests whether using an aerosol “box” during cardiopulmonary resuscitation (CPR) during an emergency improves safety and care. It’s mainly aimed at trained healthcare staff who can perform required tasks during CPR.
Los Angeles, CaliforniaAges 18–60 - NCT05868616Recruiting
Checking heart resynchronization timing with a noninvasive test
This trial evaluates a noninvasive way to assess who should get Cardiac Resynchronization Therapy (CRT), and to check results after implantation. If you fit the heart rhythm and heart pump criteria, the approach may help confirm whether CRT is appropriate for you.
OsloAges 18–80 - NCT05871216Recruiting
Study of joint instability in people with loose joints
This trial is testing how to assess and manage joint instability in people who have unusually loose (hypermobile) joints. If you have moderate to severe loose joints, you may be able to join after screening checks like movement tests and health history.
BolognaAges 18–60 - NCT05871606RecruitingPhase 1
Breathing nitric oxide during clot-removal for stroke
This Phase 1 study tests whether inhaled nitric oxide (a gas breathed through a ventilator) can improve outcomes in people having a specific kind of emergency stroke procedure to remove a clot from the brain. It focuses on patients who need general anesthesia for the clot-removal procedure and have imaging results that suggest salvageable brain tissue.
Charlotte, North CarolinaAges 18–80 - NCT05873543Recruiting
Smartphone-based exercise program for heart failure recovery
This trial tests whether a hybrid heart-rehabilitation program that uses a smartphone helps people with heart failure feel better and safely exercise. If you’re eligible, you’ll likely get guided exercise training with help from a phone app.
TaipeiAges 18–80 - NCT05872776Recruiting
Home ECG monitoring to reduce atrial fibrillation episodes
This trial uses a home heart monitor (a chest patch with an ECG) to study how atrial fibrillation (an irregular heartbeat) changes over time and how this may help manage symptoms. You may be included if you have a documented, short-lasting type of atrial fibrillation and a moderate amount of AF seen on a 14-day heart recording.
Tel AvivAges 18–85 - NCT05873881RecruitingPhase 3
Colchicine and vitamin B1 for ischemic heart failure
This study tests whether colchicine and thiamine (vitamin B1) can improve outcomes in people with heart failure caused by blocked or narrowed heart arteries. It’s mainly for people with moderate-to-severe symptoms and reduced heart pumping ability.
Hamilton, OntarioAges 45 years+ - NCT05873387Recruiting
Stethoscope tool to detect pulmonary hypertension
This study tests a computer “listening” algorithm that uses an electronic stethoscope to help detect pulmonary hypertension. It may help spot this condition earlier by turning routine heart-lung exams into more informative screenings.
Providence, Rhode IslandAges 18 years+ - NCT05873634Recruiting
Using health records and testing to study heart failure types
This study combines electronic health record data and detailed heart testing to better understand different heart failure types and what treatments may work best for each. It mainly enrolls people with known heart failure, and also some people without heart failure for comparison.
Sacramento, CaliforniaAges 30 years+ - NCT05874206Recruiting
Branch stent graft for fixing aorta problems in the chest
This trial tests whether a “branch” stent graft can safely repair certain problems in the descending aorta (the big blood vessel in the chest). It may help by sealing the problem while keeping blood flow to an important branch vessel in the left upper chest area.
ZurichAges 18 years+ - NCT05875103Recruiting
Brain and language study using a word fluency task
This study looks at how thinking and language work in people with certain brain conditions, using a simple word-finding task and brain scans. It may help researchers better understand what brain changes are linked to different symptoms.
AmiensAges 18 years+ - NCT05876000Recruiting
Heart pump study for very severe heart failure
This trial tests a left ventricular assist system (a mechanical heart pump for the left side of the heart) in people with very severe heart failure. It may help people who are too sick or not improving despite best available medical treatment.
GrazAges 18–75 - NCT05877755Recruiting
Tests a new heart MRI image method
This study checks whether a new, higher-detail heart MRI technique can produce reliable heart images. You might help researchers improve how doctors see and assess the heart during routine MRI care.
PessacAges 18 years+ - NCT05878223Recruiting
Testing different shockwave doses for ankle stiffness after stroke
This study compares different doses of shockwave treatment to reduce ankle muscle tightness (spasticity) after stroke. If you have persistent ankle stiffness and can safely receive the treatment, your results may help find the best dose for symptom relief.
HsinchuAges 20 years+ - NCT05878912Recruiting
Obesity and weight loss in certain heart failure patients
This study looks at how higher body weight and weight loss affect people who have heart failure with preserved pumping strength. It uses heart scans to measure how the heart and body change, which may help guide future treatment plans.
OxfordAges 18–85 - NCT05879913Recruiting
Heart risk check using CT scan in men on prostate cancer therapy
This study looks at how a special CT heart scan (CCTA) can help manage heart disease risk in men with prostate cancer who are taking hormone therapy (ADT). It may help your care team better assess heart risk, especially if you also have other heart risk factors but no current heart symptoms.
Carmel, IndianaAges 40 years+ - NCT05879276RecruitingPhase 3
Early empagliflozin for shock patients after ICU start
This trial studies whether starting empagliflozin early in adults with cardiogenic shock helps people live longer and have fewer hospital returns, while also checking heart pumping and kidney function. It may help some ICU patients, but eligibility is strict and depends on kidney function and prior medication use.
Ars-LaquenexyAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.