Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT05465200Recruiting
Study for cardiogenic shock treatment in adults under 24 hours
This trial is testing a treatment approach for adults with cardiogenic shock, a life-threatening condition where the heart can’t pump enough blood. You may be considered if your shock started within the last 24 hours and you meet other safety criteria.
WroclawAges 18–60 - NCT06272396Recruiting
Testing a smartwatch to record heart rhythms
This study is testing whether a connected watch (like a smartwatch) can accurately record your heart's electrical activity (an ECG) during a hospital stay or clinic visit. If it works well, it could make checking your heart easier and more convenient.
PessacAges Any age - NCT05954507Recruiting
PET/MRI scan to assess heart risk in sarcoidosis
This study checks whether a special heart scan called PET/MRI can predict how sarcoidosis may affect your heart. It may help doctors better estimate heart risk and plan follow-up based on scan findings.
CréteilAges 18 years+ - NCT05900414Recruiting
Help choosing blood thinners to prevent stroke in AF
This trial tests a web-based decision aid that helps people with atrial fibrillation (AF) decide about stroke-prevention treatment, such as blood thinners. It may help you feel more confident and make safer choices by showing options at the right time after diagnosis.
Calgary, AlbertaAges 18 years+ - NCT06342206Recruiting
TCM Assessment for Recent Ischemic Stroke
This study uses traditional Chinese medicine (TCM) diagnostic tools to evaluate patients who had an ischemic stroke within the last 10 days. It aims to understand the acute and chronic phases of stroke to help guide future treatments.
ChanghuaAges 20 years+ - NCT06420752RecruitingPhase 2
Passive stretching for peripheral artery disease
This study tests whether gentle leg stretching, done by a therapist, can improve blood flow and walking ability in people with peripheral artery disease (narrowed leg arteries). It may be an option for those who cannot do regular exercise.
La Crosse, WisconsinAges 40–90 - NCT06484829RecruitingPhase 1/Phase 2
New drug combo for relapsed or refractory multiple myeloma
This trial tests a new drug, purinostat mesylate, combined with pomalidomide (a chemotherapy pill) and a low-dose steroid (dexamethasone) for people with multiple myeloma that has returned or stopped responding to prior treatments. The goal is to see if this combination can help control the cancer with manageable side effects.
Chengdu, SichuanAges 18–75 - NCT06707103RecruitingPhase 3
Gel treatment for venous leg ulcers
This trial tests whether a special gel helps heal venous leg ulcers faster. It is for people with a diagnosed vein problem and a leg ulcer between 2 and 12 square centimeters that has been present for at least 4 weeks.
Jacksonville, FloridaAges 18 years+ - NCT06788314RecruitingPhase 2
Enalapril for painful venous malformations
This trial tests if the blood pressure drug enalapril can reduce pain from venous malformations (abnormal veins). It may help people whose pain limits daily activities or interrupts sleep.
Oslo, NorwayAges 18–70 - NCT06697093Recruiting
Polish registry for cardiogenic shock patients
This trial is a registry that collects information on diagnosis, treatment, and outcomes for people with cardiogenic shock (when the heart can't pump enough blood to the body). It may help doctors learn more about this condition and how to treat it better.
Wroclaw, Lower Silesian VoivodeshipAges 18 years+ - NCT06852209Recruiting
Brain training with neurofeedback after a stroke
This study tests a brain-training technique called neurofeedback to see if it can improve thinking skills after a stroke. If you have ongoing memory or attention problems despite recovery, this trial may help you train your brain using real-time feedback from your own brain activity.
BordeauxAges 18–75 - NCT06794008RecruitingPhase 2
CAR-T cell therapy for hard-to-treat autoimmune diseases
This trial tests a new treatment using your own immune cells (called CAR-T cells) designed to target and attack cells that cause autoimmune diseases. It is for people with lupus, Sjögren's syndrome, inflammatory myopathy, scleroderma, Behcet's disease, ANCA-associated vasculitis, IgG4-related disease, antiphospholipid syndrome, or thrombotic thrombocytopenic purpura who have not improved with standard therapies.
Beijing, Beijing MunicipalityAges 18–65 - NCT06885970Recruiting
Cytisine for smoking cessation and heart health
This study tests whether a medicine called cytisine can help people quit smoking and how it might affect their heart health. If you are a smoker without serious heart, liver, kidney, or immune problems, you may be able to join.
Athens, HaidariAges 18–75 - NCT06906432Recruiting
Brain-Heart Injury After Brain Bleed Study
This study looks at how a brain bleed can affect the heart. Researchers hope to understand the link between brain and heart injury to help improve care for people who have had a brain bleed.
Beijing, Beijing MunicipalityAges 18–80 - NCT06906744Recruiting
Study of signal loss in fetal heart monitoring during labor
This study looks at why signal loss happens during external fetal heart monitoring in labor. The goal is to improve monitoring for future pregnancies.
StrasbourgAges 18–45 - NCT03974750Recruiting
Robotics training for arm skills after stroke
This study tests whether a robotic training program can help people relearn arm and hand skills after a stroke. It also includes healthy volunteers to compare learning and movement changes.
Yvoir, NamurAges 18–90 - NCT01732523Recruiting
Check if extra blood-vessel growth predicts stroke risk in carotid narrowing
This study looks at an imaging test to see whether signs of new blood-vessel growth in an artery predict future stroke risk in people who have carotid artery narrowing but no symptoms. If it works, it could help doctors identify who may need closer monitoring or preventive treatment.
BaselAges 18 years+ - NCT02820233Recruiting
Study of a heart-signal drug during bypass surgery
This study looks at a treatment that affects signals between heart cells in people with severe coronary artery disease who are scheduled for bypass surgery. The goal is to see if changing these heart-cell signals can improve heart outcomes around the time of surgery.
Portland, MaineAges 18 years+ - NCT05530096Recruiting
Genetic test to find minimal residual myeloma in remission
This study tests a genetic technology (ClonoSeq-based) to detect very small amounts of multiple myeloma that may remain after treatment. It may help doctors better track how well treatment is working and predict how the disease responds over time.
Montreal, QuebecAges 18 years+ - NCT04813159Recruiting
Remote heart preconditioning for people with blocked-heart-attack
This study tests whether a remote, arm-based treatment done around the time of a heart attack can improve outcomes in people with STEMI (a serious heart-attack type). Some participants receive the real treatment and some receive a sham version, while others may be followed observationally depending on how long ago symptoms started.
Mombasa, Mombasa CountyAges 18 years+ - NCT06629311Recruiting
Blood recycling device study in heart surgery
This trial looks at how a device that collects and reuses your own blood during heart surgery works. It may help reduce the need for donated blood.
Strasbourg, Bas-RhinAges 18 years+ - NCT05996120Recruiting
Finding the best temperature during heart-lung machine surgery
This study looks at the best body temperature to use during heart surgery when a heart-lung machine is needed. You may be able to join if you are having bypass surgery or valve repair, your risk score is moderate or higher, and your surgery is not an emergency.
Leicester, LeicestershireAges 18 years+ - NCT05914779Recruiting
Early antibiotics after out-of-hospital cardiac arrest
This study looks at whether starting antibiotics soon after an out-of-hospital cardiac arrest helps patients who are unlikely to have an infection. Antibiotics may prevent or treat infection-related complications, but only if certain infection and health conditions are met.
Doha, Baladiyat ad DawhahAges 18 years+ - NCT07230847Recruiting
Healing of drug-coated vs. standard stents in high-bleeding-risk patients
This trial compares two types of stents (a drug-coated stent and a standard drug-eluting stent) in people with acute coronary syndrome who also have a high risk of bleeding. It uses a special camera to look at how the artery heals one month after the stent is placed.
Beijing, Beijing MunicipalityAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.