Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05841550RecruitingPhase 1/Phase 2
Vaccine study for high-risk smoldering or myeloma
This Phase 1/2 trial tests a cancer vaccine (TG01/QS-21) in people with high-risk smoldering multiple myeloma or multiple myeloma. It aims to see how safe the vaccine is and whether it can help the immune system control the disease.
Oslo, OsloAges 18 years+ - NCT05841615Recruiting
Atrial fibrillation and high blood pressure ablation plus kidney nerve treatment
This trial tests whether treating atrial fibrillation with a catheter procedure plus treating high blood pressure through kidney nerve treatment works better together. It may help control rhythm and blood pressure, but you must meet several heart, kidney-artery, and safety requirements.
Xiamen, FujianAges 18–75 - NCT05841784Recruiting
Mindfulness coaching for stress and mood after heart risk
This study tests a structured mindfulness program (MBCT-T) to help people who have elevated stress and/or mild anxiety or depression in the setting of heart disease or heart risk factors. It may help improve emotional well-being and stress levels while you live with these health concerns.
New York, New YorkAges 18 years+ - NCT05841745Recruiting
Registry of robotic heart procedure for blocked coronary arteries
This registry collects real-world information about people having a robotic-assisted heart procedure (PCI) for blocked coronary arteries. It may help doctors understand how well this approach works for different heart conditions.
AalstAges 18 years+ - NCT05842551Recruiting
Prism glasses and brain stimulation after stroke
This trial studies whether prism lenses and a mild brain-stimulation treatment can help people who have stroke-related “neglect,” where they don’t notice one side of the body or space. If you qualify, the goal is to see if these treatments improve attention and daily functioning after a recent ischemic stroke.
Bari, BaAges 18–90 - NCT05844501RecruitingPhase 4
Ondansetron before heart ablation for atrial fibrillation
This trial tests whether ondansetron can help people with atrial fibrillation (an abnormal heart rhythm) around the time of elective catheter ablation. It may improve the safety or effectiveness of the procedure by targeting a pathway involved in heart rhythm events.
Indianapolis, IndianaAges 18–100 - NCT05845047Recruiting
Telemedicine speech therapy for stroke-related language problems
This trial tests a home-based (telemedicine) therapy that uses focused brain “engagement” exercises to help improve language after a stroke. It is meant for adults with stroke-related aphasia (language difficulty) and checks whether you can participate reliably with the tasks.
Baltimore, MarylandAges 18–99 - NCT05845541Recruiting
Meditation and body feedback for mood after stroke
This study tests whether guided meditation and biofeedback can improve anxiety, depression, and quality of life for people recovering in inpatient rehab after a recent stroke. It may help you feel better emotionally and cope more easily during recovery.
Toronto, OntarioAges 18 years+ - NCT05845905Recruiting
Remote arm treatment to lower blood pressure in older adults
This study tests whether a simple “remote conditioning” method done on the arm can help lower blood pressure in older adults with hypertension. It may help people whose blood pressure is high but not dangerously high at the time of screening.
Changchun, JilinAges 65–85 - NCT05845489RecruitingPhase 4
Clopidogrel to prevent heart problems from minor artery plaque
This trial tests whether clopidogrel (a blood-thinning medicine) can prevent future heart attacks or strokes in people who have early, “subclinical” plaque in their heart arteries. You may be considered if scans show plaque but not major artery blockage that needs a procedure.
Seoul, OtherAges 40 years+ - NCT05846321Recruiting
Registry for blood vessel injury after trauma follow-up
This study keeps a registry of adults with injuries to blood vessels caused by trauma and tracks follow-up outcomes. Your participation may help doctors better understand how these injuries heal and how to manage them.
AugsburgAges 18 years+ - NCT05845723RecruitingPhase 2
Study drugs for blood-vessel Behçet’s to reduce inflammation
This Phase 2 trial tests tocilizumab and tofacitinib to see if they can better control vascular (blood-vessel) Behçet’s syndrome. It may help by lowering inflammation and reducing complications from aneurysms in the aorta or peripheral arteries.
Beijing, Beijing MunicipalityAges 18–65 - NCT05846880RecruitingEarly Phase 1
Vitamin D3 supplement for people with multiple myeloma
This early-phase study tests whether taking a Vitamin D3 supplement can be safe and helpful for people with symptomatic multiple myeloma. It may help researchers understand how Vitamin D affects the disease and how patients tolerate treatment.
Augusta, GeorgiaAges 18 years+ - NCT05847569RecruitingPhase 2
Testing alternating doses of belantamab for hard-to-treat myeloma
This Phase 2 trial tests whether alternating doses and schedules of belantamab mafodotin can help people with multiple myeloma that has returned or kept progressing after several prior treatments. You may be eligible if your disease has specific measurable signs and your blood counts and organs are healthy enough for study treatment.
Jacksonville, FloridaAges 18 years+ - NCT05847699Recruiting
MRI study of stroke brain changes after decompression surgery
This study looks at how MRI findings match what doctors see in brain tissue after treatment for a type of severe stroke. It may help researchers better understand which brain changes happen early and how decompressive surgery affects them.
ParisAges 18 years+ - NCT05848284Recruiting
Tricuspid valve replacement to reduce leaking in the heart
This trial tests a new catheter-based procedure that replaces the tricuspid valve to reduce severe valve leaking. It may help people who still have symptoms despite heart medicines, but only if their heart shape and other health details fit the device requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT05849025Recruiting
MRI heart study using blood-pressure and kidney checks
This study adds an MRI and other measurements to a heart registry to better understand heart function. You might benefit by getting detailed heart and kidney measurements, but you must meet safety and eligibility rules (like blood pressure, BMI, and being off heart medicines).
Rochester, MinnesotaAges 18 years+ - NCT05849389RecruitingPhase 2
Vosoritide for taller growth in girls with Turner syndrome
This Phase 2 study tests vosoritide to help children with Turner syndrome grow taller before puberty. You may be able to join if your child is pre-pubertal, has short height for age, and either has not tried growth hormone or has not responded well to it.
Washington D.C., District of ColumbiaAges 3–11 - NCT05849896Recruiting
Tests how muscle-monitor signals work after stroke rehab
This study checks how well a device’s surface muscle signals (recorded on the skin) match what happens during post-stroke rehabilitation tasks. It may help improve how rehab progress is measured, using information from both healthy participants and people after a first stroke.
LuganoAges 18–99 - NCT05850247RecruitingPhase 2
Study brain inflammation in carotid artery narrowing after stroke or TIA
This Phase 2 study looks at a protein called ficolin-2 and whether it relates to brain inflammation after a short stroke-like event or eye blood vessel blockage caused by narrowed carotid arteries. If you recently had symptoms from the carotid artery and meet imaging and health criteria, you may be offered study-related assessments to better understand the cause and help future treatment decisions.
BronAges 18 years+ - NCT05887700Recruiting
Follow-up check for an ASD device closure
This study follows people who had an atrial septal defect (a hole between heart chambers) closed using a specific device. It aims to collect outcomes and safety information after the hospital procedure.
CuritibaAges Any age - NCT05875116Recruiting
Virtual reality therapy for arm weakness after stroke
This trial tests whether virtual reality training plus a specific arm-movement approach helps people regain function after a stroke. It focuses on improving arm weakness on one side of the body during the early months after leaving the hospital.
Mexico CityAges 35–70 - NCT05909059RecruitingPhase 2
CAR-T therapy for people with kidney function problems
This study tests a type of immune treatment (CAR-T) in people whose kidneys are not working well, using chemotherapy first to help the CAR-T work. It may help people with certain blood cancers who have reduced kidney function to still receive CAR-T therapy safely.
Atlanta, GeorgiaAges 18 years+ - NCT05851053Recruiting
Study of heart function years after breast cancer treatment
This study checks how well your heart works long after breast cancer treatment. If you joined the earlier de BLOC-I study, you may be invited for follow-up to understand long-term heart effects.
GroningenAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.