Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT06263920Recruiting
Study on late-onset epilepsy and its links
This study looks at people who had their first seizure or were diagnosed with epilepsy after age 18, and compares them to people with migraine. The goal is to understand what might be connected to epilepsy that starts later in life.
Preston, LancashireAges 18 years+ - NCT06776419Recruiting
Heart inflammation and scarring in Fabry disease
This study uses advanced heart scans (PET/CT and MRI) to look at inflammation, blood vessel health, and scarring in the hearts of people with Fabry disease. It aims to better understand how Fabry disease affects the heart and find new ways to track or treat these changes.
CopenhagenAges 18 years+ - NCT06598280Recruiting
Going home same day vs staying overnight after afib ablation
This trial compares whether it is safe to go home a few hours after a heart procedure for atrial fibrillation (afib) versus staying in the hospital overnight. It will help doctors understand which approach is better for your recovery.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT06861582Recruiting
Faster troponin test for chest pain in the ER
This study tests a faster way to measure a heart-muscle protein (troponin) in the emergency room, to see if it can help doctors decide sooner whether your chest pain is from a heart attack. If you are having chest pain that started a few hours ago, you may be able to join.
São PauloAges 18 years+ - NCT06917066Recruiting
Registry for severe aortic stenosis patients getting a specific TAVR valve
This study tracks patients with severe aortic stenosis who receive the Myval transcatheter heart valve during TAVR (a less-invasive valve replacement). It aims to understand how well the valve works over time.
Valladolid, ValladolidAges 18 years+ - NCT06916663Recruiting
Upper body vs. combined exercise during diabetic foot ulcer treatment
This trial compares two exercise programs for people with diabetic foot ulcers: one that uses only upper body exercises and one that combines upper body with non-weight bearing lower body exercises. The goal is to see which approach helps healing while keeping weight off the foot.
CairoAges 18–65 - NCT07218276Recruiting
Passive robot study for stroke recovery
This study tests a passive robot (a device that moves without force) to help stroke survivors regain arm movement. It aims to see if this approach is safe and helpful for people with arm weakness after a stroke.
Ann Arbor, MichiganAges 18–75 - NCT07212803RecruitingPhase 4
Energy drinks study for young healthy adults
This study looks at how energy drinks affect your heart. It compares the effects of two different energy drinks on heart rate and other heart measures. You will have several short visits where you drink an energy drink and get your heart checked.
Stockton, CaliforniaAges 18–40 - NCT07219108Recruiting
Ear stimulation to help recovery in the neuro ICU
This study tests a gentle device that stimulates a nerve in the ear to see if it helps patients in the neuroscience intensive care unit recover from serious brain or spinal cord conditions. It might reduce complications and improve recovery.
St Louis, MissouriAges 18 years+ - NCT07214350Recruiting
Physical Activity Barriers in Cardiac Rehab by Sex
This study looks at how men and women differ in getting started and staying active during and after cardiac rehab. You will use a mobile app to track your activity and answer questions, helping researchers find better ways to support heart health.
Durham, North CarolinaAges 18 years+ - NCT07221279Recruiting
Walking study for weight and heart health in adults
This study tests if a specific number of daily steps can help overweight or obese adults improve body composition and reduce heart disease risk. It's for people who are otherwise healthy but may have high blood pressure or joint pain managed by medication.
Kennesaw, GeorgiaAges 20 years+ - NCT07220525Recruiting
Sleep and heart rhythm study for people with sleep apnea device
This study looks at how turning off your sleep apnea device for short periods affects your heart rhythm, especially if you have a condition like atrial fibrillation. It may help understand the link between sleep and heart health.
San Francisco, CaliforniaAges 21 years+ - NCT07218094Enrolling by invitation
Exosuit walking study for chronic stroke survivors
This study tests a robotic leg suit (exosuit) to help improve walking after a stroke. You may be eligible if you had a stroke more than 6 months ago and still have trouble walking safely.
Boston, MassachusettsAges 18 years+ - NCT07220798Recruiting
A program to support caregivers of people with heart failure and memory problems
This study tests a program to help caregivers of people with heart failure and memory problems take better care of themselves, so they can feel better and support their loved one more effectively.
New York, New YorkAges 18–101 - NCT07215416RecruitingPhase 1/Phase 2
Gene therapy for ataxia-telangiectasia with specific ATM mutation
This trial tests a new genetic medicine designed for people with A-T who have a specific ATM gene change. It aims to see if the treatment is safe and if it can improve symptoms.
Boston, MassachusettsAges birth–17 years - NCT07221214RecruitingPhase 2
Testing a diabetes drug for drinking and heart health in HIV
This trial tests if a once-weekly diabetes medication (semaglutide) can help people with HIV reduce heavy drinking and improve heart health. It's for people who drink alcohol and have a higher body weight.
Nashville, TennesseeAges 18–89 - NCT07220005Recruiting
Ultrasound brain stimulation for arm weakness after stroke
This study tests a new non-invasive therapy using low-intensity focused ultrasound to stimulate the brain area affected by a stroke, which may help improve arm weakness in people who have had a stroke more than 6 months ago.
Durham, North CarolinaAges 21 years+ - NCT07220226Recruiting
Fontan circulation and venous compression study
This trial looks at how blood flow works in people with Fontan circulation, who have a unique heart surgery. It aims to understand vein compression and may help guide future care.
Dallas, TexasAges 18–45 - NCT07215195Recruiting
Brain injury, sleep, and mental health study
This study looks at how brain injuries affect sleep and mental health in the months after injury. It is for people who have had a stroke, brain bleed, or traumatic brain injury within the past year and are willing to let the research team contact their doctor if needed.
OxfordAges 18 years+ - NCT07212686Enrolling by invitationPhase 4
Angiotensin II for severe low blood pressure in children
This study tests an IV medicine called angiotensin II (Giapreza) to raise blood pressure in children who are very sick and not responding to standard treatments. It aims to see if this medicine can help stabilize blood pressure and improve outcomes.
New Hyde Park, New YorkAges birth–18 years - NCT07217522Recruiting
Genetics of pulmonary hypertension study
This study looks at the genes that may be linked to pulmonary hypertension. By providing a saliva sample and filling out a health survey from home, you can help researchers learn more about this condition.
Piscataway, New JerseyAges 18 years+ - NCT07213531Recruiting
AI guidance for heart valve treatments
This trial uses artificial intelligence to improve outcomes for patients getting minimally invasive heart valve procedures. It looks at CT scans and ultrasound images to help doctors plan and perform treatments for the aortic, mitral, and tricuspid valves.
New York, New YorkAges 18 years+ - NCT07217366Enrolling by invitation
Speech-to-text tool for heart failure patients
This study tests a speech-to-text tool to help people with heart failure report their symptoms and health information more easily. It aims to see if using voice instead of typing can improve data collection.
Palo Alto, CaliforniaAges 18 years+ - NCT07217236Recruiting
AI ECG to predict need for heart device
This trial uses artificial intelligence to analyze your ECG to see if you might be at risk for needing a heart device like a pacemaker. It's a way to check your heart health early.
TaipeiAges 65–90
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.