Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07219108Recruiting
Ear stimulation to help recovery in the neuro ICU
This study tests a gentle device that stimulates a nerve in the ear to see if it helps patients in the neuroscience intensive care unit recover from serious brain or spinal cord conditions. It might reduce complications and improve recovery.
St Louis, MissouriAges 18 years+ - NCT03789552RecruitingPhase 3
Testing T89 to prevent chest pain during stable angina
This Phase 3 trial tests whether T89 reduces angina (chest pain caused by heart-related reduced blood flow) in people with stable angina. You may help confirm the treatment’s benefit by completing symptom tracking and exercise heart tests over several weeks.
Naples, FloridaAges 18–90 - NCT05884190Recruiting
Help for early high blood pressure after childbirth
This study tests a “trauma-informed” approach to detect and manage high blood pressure soon after delivery. It may help you get faster support and safer treatment during the early postpartum period.
New Haven, ConnecticutAges 18 years+ - NCT04964765Recruiting
3D heart mapping after early irregular heartbeat after surgery
This study uses 3D heart mapping to understand a specific kind of irregular heartbeat that can happen soon after cardiac surgery. It may help doctors better recognize what’s happening in the heart during the early recovery period.
Sankt PöltenAges 18 years+ - NCT05216666Recruiting
Surgery type and leftover limping after hip replacement
This study looks at whether the kind of hip surgery approach affects how much limping remains after a total hip replacement. You may benefit by helping researchers find the approach that leads to better walking after surgery.
MölndalAges 40–80 - NCT05960604Recruiting
Monitoring blood pressure during surgery to predict low blood pressure
This study tests special ways of analyzing blood-pressure recordings during major surgery to better understand why some people develop low blood pressure (hypotension). If you have high blood pressure and need invasive blood-pressure monitoring, your surgery team will use readings to study patterns that may help predict or prevent low blood pressure.
AnkaraAges 18 years+ - NCT06500611Recruiting
Sensory balance exercises for stroke recovery
This trial tests if combining sensory integration and vestibular exercises helps improve balance in people who have had a stroke and also have dizziness or balance problems. It may help you walk better and feel steadier.
Lahore, Punjab ProvinceAges 40–65 - NCT06920173RecruitingPhase 2
Low-dose vasopressors for shock in the ICU
This study tests whether giving low-dose blood pressure medicines through a standard IV (instead of a larger central line) is safe and effective for patients with shock in the intensive care unit.
Kingston, OntarioAges 18 years+ - NCT06918301Recruiting
Comparing heart measurements in cardiac surgery patients
This trial compares three ways to measure how well your heart pumps blood after cardiac surgery. It uses a standard catheter and two newer monitors to see which is most accurate.
KarlsburgAges 18 years+ - NCT06920563Recruiting
Remote blood pressure monitoring after childbirth
This trial tests a program that lets you monitor your blood pressure at home after childbirth and learn about heart health. It's for women who had high blood pressure for the first time during pregnancy and are in the Ochsner system.
New Orleans, LouisianaAges 18 years+ - NCT05774938Recruiting
Quality of life after minimally invasive aortic repair
This study looks at how people’s quality of life changes after a planned minimally invasive procedure to repair the aorta using EVAR, FEVAR, or BEVAR. It may help doctors better understand what recovery and day-to-day wellbeing are like for patients after this kind of treatment.
StockholmAges 18 years+ - NCT05945524Recruiting
Study of how teclistamab works in multiple myeloma patients
This study looks closely at patients’ immune cells to understand why teclistamab helps in multiple myeloma. Your participation could help doctors better predict who benefits and how the treatment works.
Amiens, FranceAges 18 years+ - NCT05817305Recruiting
Exercise program for people with past heart problems
This trial looks at adding regular exercise to everyday life for people who have had previous heart events. It aims to improve safety and day-to-day health by monitoring who can exercise safely.
Ferrara, FerraraAges 18 years+ - NCT06696027Recruiting
Loss of Y chromosome in autoimmune and lung disease
This study looks at how the loss of the Y chromosome in blood cells may be linked to autoimmune and lung diseases in older men. By joining, you help researchers understand this connection better.
Bonn, North Rhine-WestphaliaAges 50 years+ - NCT06460142Recruiting
Biomarker study for giant cell arteritis and polymyalgia rheumatica
This study is looking for biomarkers (biological clues) in people with newly diagnosed or flaring giant cell arteritis (GCA) or polymyalgia rheumatica (PMR). Participating may help researchers find better ways to diagnose and monitor these conditions.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06705543Recruiting
Genetic study of complex heart defects in unborn babies
This study looks at the genetic material in the fluid around the baby (amniotic fluid) and in the placenta to better understand complex heart defects in unborn babies. The goal is to find new clues that could help doctors care for these babies before and after birth.
BordeauxAges 18 years+ - NCT06835946Recruiting
How anesthesia and imaging affect heart valve leak assessment
This study looks at how anesthesia, breathing machines, and imaging methods change the way doctors measure a leaky heart valve. It aims to make sure the severity of aortic regurgitation is accurately measured before surgery.
LiègeAges 18 years+ - NCT06914778Recruiting
How diabetes affects the eyes in South Wales
This study looks at how fat and sugar levels in the blood relate to different stages of eye damage in people with type 2 diabetes. It may help find new ways to treat or prevent vision loss.
Llanelli, WalesAges 18–80 - NCT04962646Recruiting
Breathing extra carbon dioxide during surgery to prevent brain injury
This trial tests whether giving extra carbon dioxide during surgery can reduce the chance of new brain or nervous system injury after surgery for a sudden, life-threatening tear in the big artery (type A aortic dissection). It may help by protecting the brain while the surgical team repairs the artery.
LundAges 18 years+ - NCT05504941Recruiting
Testing a treatment target map in sudden brain bleeding
This study looks at a special scan (DSA, done with contrast dye) to find a likely “target” that doctors can use when treating sudden brain bleeding. It’s meant to help doctors better understand where treatment may be needed soon after symptoms start.
BaselAges 18 years+ - NCT06424912Recruiting
BPH treatment via vein connection for enlarged prostate
This trial tests a new treatment for enlarged prostate (BPH) that targets veins in the scrotum to improve urinary symptoms. It may be an option if you have both BPH and a varicocele and haven't had prior prostate surgery.
Panama City, Provincia de PanamáAges 40–75 - NCT06685042RecruitingPhase 1/Phase 2
CAR T-cell therapy for severe autoimmune diseases
This study tests a new treatment called CAR T-cell therapy for people with severe autoimmune diseases that haven't gotten better with standard treatments. The goal is to see if it can help control the disease by reprogramming your immune cells.
Rome, LazioAges 18–65 - NCT06572085RecruitingPhase 4
Butylphthalide for brain protection after cardiac arrest
This trial tests a medicine called butylphthalide (NBP) to see if it helps protect the brain after a cardiac arrest. It is for adults who remained unconscious after their heart was restarted.
Beijing, Beijing MunicipalityAges 18–80 - NCT06741995Recruiting
Testing antibodies to predict heart muscle disease progression
This study looks at whether certain antibodies (proteins in your blood) can help predict how dilated cardiomyopathy will progress. By testing your blood, researchers hope to learn more about your condition and find better ways to manage it.
Wuhan, HubeiAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.