Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05983757Recruiting
Clot retrieval for smaller brain artery strokes
This trial tests if removing clots from smaller arteries in the brain (not the main ones) helps people who had a stroke and can't get standard clot-busting medicine. It compares clot removal to usual care for strokes caused by these medium-sized vessel blockages.
Atlanta, GeorgiaAges 18 years+ - NCT05985213Recruiting
Brain blood vessel disease study at Yueyang Hospital
This study follows people with small vessel brain disease to understand how it changes over time. You may join if you've had an MRI showing this type of brain change and are able to take care of yourself daily.
ShanghaiAges 18–80 - NCT05985447Recruiting
Menopause and blood cell function study
This study looks at how menopause affects blood cells and platelets in people with heart or lung conditions. It may help understand why risks change after menopause.
DüsseldorfAges 18 years+ - NCT05986487Recruiting
Sleep apnea treatment for better blood pressure control
This trial tests whether treating sleep-disordered breathing (like sleep apnea) can help lower blood pressure in people with high blood pressure. You may join if you have high blood pressure and haven't been diagnosed with a sleep disorder before.
LleidaAges 18 years+ - NCT05987124RecruitingPhase 2
Higher dose defibrotide for SOS after stem cell transplant
This study tests whether a higher dose of defibrotide can help patients who develop SOS/VOD after a stem cell transplant and haven't gotten better with the standard dose. SOS/VOD is a liver condition that sometimes also affects the kidneys or lungs.
Vallhala, New YorkAges 1 month–75 years - NCT05989139Recruiting
Oxygen mask vs. breathing machine for sudden fluid in the lungs
This trial compares two ways to help people who have a sudden buildup of fluid in the lungs (acute pulmonary edema) breathe easier. One uses a simple oxygen mask, the other uses a machine that pushes air into your lungs. The results may help doctors choose the best treatment for you.
RomaAges 18 years+ - NCT05989152Recruiting
PET scan to check heart valve infection after antibiotics
This trial uses FDG-PET scans to see if a heart valve infection (endocarditis) is cured after antibiotics. It is for people with a prosthetic valve who had an active infection and a specific PET scan early in treatment.
Paris, FranceAges 18 years+ - NCT05989620Recruiting
Long-term study of muscular dystrophy functions
This study tracks changes in muscle strength and breathing over time in people with certain types of muscular dystrophy. It helps researchers develop better tests to measure how the disease progresses.
Richmond, VirginiaAges 6–50 - NCT05989581RecruitingPhase 1
High blood pressure in early pregnancy treatment study
This study tests whether treating mild high blood pressure early in pregnancy (before 20 weeks) can improve outcomes for you and your baby. It compares taking medication versus monitoring without medication.
Birmingham, AlabamaAges 14–89 - NCT05991219Recruiting
Rheumatic heart disease screening and prevention study
This study is looking for people living in rural areas of Sindh, Pakistan, to help screen for and prevent rheumatic heart disease. It aims to find and treat the condition early.
Karachi, SindhAges 10–30 - NCT05992532Recruiting
Study of rare enzyme disorders in monoclonal gammopathy or myeloma
This study looks for two rare inherited disorders—Gaucher disease and acid sphingomyelinase deficiency (ASMD)—in people who already have a blood condition like monoclonal gammopathy (abnormal protein) or multiple myeloma. If you have an enlarged spleen or low platelets, you may be eligible to help researchers understand if these rare diseases are more common in this group.
Vitoria-Gasteiz, AlavaAges 18–99 - NCT05993091Recruiting
Mirror therapy and augmented reality for stroke recovery
This study tests whether combining mirror therapy with augmented reality (a computer-generated view of your arm) helps improve arm movement and daily function after a stroke. It may be a good fit if you have some arm movement and can walk.
New Taipei CityAges 30–80 - NCT05993221Recruiting
Understanding arm weakness after stroke
This study looks at the brain changes that happen after a stroke and how they affect arm movement. It uses MRI scans and gentle magnetic pulses to understand your brain better, which may help guide future treatments.
Providence, Rhode IslandAges 18–90 - NCT05994014Recruiting
Comparing two heart scans for artery blockages
This study compares two types of heart scans to see which one better finds blockages in the arteries of people with chest discomfort or shortness of breath when active. You will have both a special CT scan and a PET/CT scan to check the health of your heart arteries.
Baltimore, MarylandAges 18 years+ - NCT05994664Recruiting
Heart Coherence Training for Vascular Ehlers-Danlos
This study tests whether a breathing and heart-rate training program (called Heart Coherence Training) can help people with Vascular Ehlers-Danlos syndrome feel better. It's done from home using your phone and a computer or tablet.
Houston, TexasAges 12–45 - NCT05996120Recruiting
Finding the best temperature during heart-lung machine surgery
This study looks at the best body temperature to use during heart surgery when a heart-lung machine is needed. You may be able to join if you are having bypass surgery or valve repair, your risk score is moderate or higher, and your surgery is not an emergency.
Leicester, LeicestershireAges 18 years+ - NCT05995600RecruitingPhase 4
Clopidogrel vs warfarin to prevent a second APS stroke
This study compares two types of blood thinners — clopidogrel (an antiplatelet) and warfarin — to prevent another stroke in people with antiphospholipid syndrome (APS). It aims to find which medicine works better for people who have already had a stroke related to APS.
AnyangAges 19 years+ - NCT05996159Recruiting
Using very high power for short duration to treat atrial fibrillation
This study tests a new way to perform a common procedure (pulmonary vein isolation) for people with paroxysmal atrial fibrillation. Instead of using the standard amount of energy for a longer time, this method uses a very high amount of energy for a very short time. This might make the procedure faster and just as safe.
SeoulAges 19 years+ - NCT05996211Recruiting
Swiss Study on Brain Development in Children with Heart Defects
This study follows children with severe heart problems born recently to see how their brain development progresses. It helps doctors understand what support these children might need as they grow.
BernAges 1 week–1 month - NCT05996367Recruiting
Single radiation dose for painful myeloma bone lesions
This trial is testing whether a single dose of radiation can effectively relieve bone pain caused by multiple myeloma. It is designed for people who have a painful bone lesion and are stable on or off treatment.
São Paulo, São PauloAges 18–85 - NCT05997680Recruiting
Yoga for attention in kids with heart disease
This study tests if a parent-child yoga program can help improve attention in children aged 4 to 6 with congenital heart disease who have attention difficulties. You and your child would attend yoga sessions together for 8 weeks.
Montreal, QuebecAges 4–6 - NCT05997732RecruitingPhase 4
Blood Pressure Control: Sex Differences in Healthy Adults
This study looks at how the nervous system controls blood pressure differently in men and women. It involves a single visit where you'll receive a small dose of medications through an IV and have your nerve activity and blood pressure measured.
Edmonton, AlbertaAges 18–40 - NCT05998694Recruiting
Monitoring a new aortic heart valve for safety and effectiveness
This trial tests how well a new replacement heart valve works and how safe it is. You might qualify if you need a planned first-time aortic valve replacement and are 60-70 years old (or younger if you cannot take blood thinners).
Kemerovo, Kemerovo OblastAges 60–70 - NCT05998928RecruitingPhase 2
BCMA-GPRC5D CAR-T for relapsed or refractory multiple myeloma
This trial tests a new cell therapy (CAR-T) that targets two proteins on myeloma cells for patients whose cancer has returned or not responded after at least three prior treatments. It aims to see if this therapy is safe and effective.
Wuhan, HubeiAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.