Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06107452Recruiting
Personalized heart rehab after a heart attack
This trial tests a personalized heart rehab program based on your muscle strength and heart rate patterns. It aims to improve recovery after a recent heart procedure.
Saint-EtienneAges 18 years+ - NCT06107361Recruiting
Guidewire use for ultrasound-guided IVs
This trial tests whether using a special guidewire during ultrasound-guided IV placement helps the IV last longer. It may be a good option if you have hard-to-find veins and need an IV.
Royal Oak, MichiganAges 18 years+ - NCT06107738RecruitingPhase 2
Iberdomide and Daratumumab after stem cell transplant for multiple myeloma
This trial tests two medicines, iberdomide and daratumumab, given as maintenance therapy after an autologous stem cell transplant. It is for people with multiple myeloma who still have small amounts of cancer cells detected after transplant and who have already been treated with a daratumumab-containing regimen.
Detroit, MichiganAges 18 years+ - NCT06108076RecruitingEarly Phase 1
Oral ketones for heart failure and diabetes
This study tests whether taking a special oral ketone supplement can help people with both heart failure and diabetes. It looks at both short-term and long-term effects on heart function and blood sugar control.
San Antonio, TexasAges 18–80 - NCT06108674Recruiting
Phone-based pharmacist help for high blood pressure in seniors
This trial tests if a pharmacist can help older adults with uncontrolled high blood pressure manage it better through phone calls. It might be a good fit if you have a cell phone and your blood pressure is not under control.
Vitória da Conquista, Estado de BahiaAges 60 years+ - NCT06108414RecruitingPhase 4
Low-dose vs standard-dose blood thinner for older adults with atrial fibrillation
This trial tests whether a lower dose of the blood thinner rivaroxaban works as well as the standard dose for people 70 and older with atrial fibrillation (an irregular heartbeat). The goal is to find the safest dose to prevent strokes while reducing bleeding risks.
Beijing, Beijing MunicipalityAges 70 years+ - NCT06109233Recruiting
MRD-guided treatment for newly diagnosed myeloma
This study is for people with newly diagnosed multiple myeloma whose cancer responded to initial treatment but still has tiny traces (minimal residual disease, or MRD). The trial will test if adjusting the next phase of therapy based on MRD levels can improve long-term outcomes.
Changchun, JilinAges 18 years+ - NCT06109324Recruiting
Robotic exercises for sensory and cognitive recovery after stroke
This study tests whether robotic exercises can improve sensory and cognitive abilities in people who recently had a stroke. It may help you regain better function in your daily activities.
FlorenceAges 18–85 - NCT06111599Recruiting
Thermovision-guided lumbar nerve block for severe leg pain
This trial tests a procedure called a lumbar sympathetic block (a numbing injection around nerves in your lower back) guided by a special heat-sensing camera. It aims to improve blood flow and reduce severe leg pain caused by chronic limb-threatening ischemia.
KošiceAges 20–80 - NCT06112171Recruiting
Comparing treatments for leg artery blockages with severe calcium
This trial tests a special preparation method (breaking up calcium) plus a Supera stent versus standard preparation plus stenting for people with severe calcium buildup and long blockages in the thigh or behind-the-knee artery. It aims to see which approach works better for opening the artery and keeping it open.
Leipzig, SaxonyAges 18 years+ - NCT06113380Recruiting
Robot arm therapy for stroke recovery
This trial tests if a robot can help people recovering from a first stroke improve arm and hand movement. It compares robot-assisted therapy to standard rehabilitation exercises.
TaipeiAges 20–85 - NCT06113510Recruiting
Clot imaging for heart attacks with clear arteries
This study uses a special type of MRI to look for tiny blood clots in the heart arteries that may have caused a heart attack even when standard tests show no major blockages. It aims to better understand the cause of heart attacks in people with this uncommon pattern.
EdinburghAges 18 years+ - NCT06114329RecruitingPhase 2
Oral AL01211 for untreated men with Fabry disease
This study tests an oral medication called AL01211 for men who have classic Fabry disease but have never been treated before. The goal is to see if it is safe and if it can help reduce the build-up of fatty substances in the body.
Guangzhou, GuangdongAges 18–60 - NCT06114615Recruiting
Remote monitoring after heart treatment to prevent future events
This trial tests whether digital tools can help monitor patients after a stent procedure to lower the chance of another heart problem. It aims to make follow-up care easier and more effective.
Sacramento, CaliforniaAges Any age - NCT06114732Recruiting
Walking improvement study for leg pain from PAD
This study tests if a combination of a behavioral program and electrical stimulation (TENS) can help people with peripheral artery disease walk farther with less pain. It aims to boost physical activity and quality of life.
Glasgow, LanarkshireAges 18 years+ - NCT06115122Recruiting
PEPPI Study: Finding early signs of placental problems in pregnancy
This study looks at blood markers to find women at risk for placental problems during pregnancy. It involves blood tests in early and late pregnancy, and at birth, to see how iron levels and other factors affect the placenta and baby's health.
OuluAges Any age - NCT06115096Recruiting
Heart pump blood flow study
This study looks at how blood flows inside your heart while you have a HeartMate 3 heart pump. It aims to understand your heart’s pumping function and may help doctors improve care for people with heart pumps.
Linköping, Östergötland CountyAges 18 years+ - NCT06115135RecruitingPhase 2
Venetoclax with isatuximab and dexamethasone for myeloma
This trial tests a combination of three drugs (venetoclax, isatuximab, and dexamethasone) for people with multiple myeloma that has come back or stopped responding to earlier treatments. It is for patients whose cancer cells have a specific genetic change, called t(11;14).
West Hollywood, CaliforniaAges Any age - NCT06115759Recruiting
Recovery and activity study after open-heart surgery
This study tests a new recovery plan called T-REX to see if it helps patients feel better and get back to moving sooner after open-heart surgery. It is for people having surgery at Thorax Centrum Twente.
Enschede, OverijsselAges 18 years+ - NCT06115980Recruiting
Testing a new device for heart device lead removal
This trial tests the safety and early performance of the Xtrac O.S. system, a new tool designed to remove old pacemaker or defibrillator leads. It may help patients who need their leads taken out after being in place for 1 to 5 years.
JerusalemAges 18–85 - NCT06116630Recruiting
Brain health after stroke risk factors study
This study looks at how well the brain works after a stroke or in people with stroke risk factors. It uses a special MRI scan to understand brain changes that may affect thinking and memory.
Palo Alto, CaliforniaAges 45–90 - NCT06116942Recruiting
Brain stimulation and computer training for arm recovery after stroke
This trial combines magnetic brain stimulation with computer-based motor training to help improve arm and hand function in people who had a stroke at least 6 months ago. It may be a good fit if you have moderate to severe weakness on one side and can take part in brain-computer interface training.
Leipzig, SaxonyAges 20–80 - NCT06117527Recruiting
Placenta learning model for aneurysm surgery training
This trial uses donated placentas (surgical waste) to create a model for training neurosurgeons in repairing brain aneurysms. It does not test a treatment, but helps improve surgical skills.
StrasbourgAges 18 years+ - NCT06118034RecruitingPhase 3
Colchicine for heart surgery recovery
This study tests whether the drug colchicine can reduce inflammation and protect organs during and after planned heart surgery. It may help people recover better.
Nanjing, JiangsuAges 50–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.