Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06218199RecruitingPhase 4
Diuretics vs. blood pressure meds for HeartLogic alerts
This trial compares two treatments—diuretics (water pills) and a blood pressure medication called sacubitril/valsartan—to see which works better when your heart device sends an alert. It's for people with a Boston Scientific heart device that has HeartLogic alerting turned on.
Huntsville, AlabamaAges 19 years+ - NCT06218355Recruiting
Improving postpartum care access through telemedicine
This study tests whether telemedicine visits after childbirth can improve access to care for new moms. Women who delivered at Parkland Hospital or Grady Health and get follow-up care at their community clinics may be able to join.
Atlanta, GeorgiaAges 18 years+ - NCT06218654Recruiting
Blood flow changes after spontaneous brain bleed
This study looks at how the body's blood flow, heart rate, and blood pressure change in people who have had a spontaneous brain bleed. It aims to learn better ways to monitor and care for these patients to improve recovery.
RomaAges 18 years+ - NCT06218875Recruiting
Registry for GORE EXCLUDER aneurysm treatment
This registry tracks how well the GORE EXCLUDER and Iliac Branch devices work for treating abdominal aortic aneurysms over time. It's a way to gather real-world data to help doctors and patients make better treatment decisions.
Little Rock, ArkansasAges 18 years+ - NCT06220032RecruitingPhase 3
Preventing heart damage from chemotherapy in lymphoma
This trial tests if the drug dexrazoxane can protect the heart during chemotherapy for a type of lymphoma called DLBCL. It may be an option for patients starting a standard treatment regimen known as R-CHOP.
's-HertogenboschAges 18 years+ - NCT06219889Recruiting
Study of Neurocheck effects on thinking after brain bleed
This study looks at how a quick thinking-and-memory check (called a Neurocheck) affects patients recovering from a small, stable brain bleed in the ICU. It helps doctors understand if these checks are helpful for your recovery.
San Diego, CaliforniaAges 18–100 - NCT06220006Recruiting
Comparing heart tissue burns for atrial fibrillation treatment
This study compares two ways to create small burns in the heart tissue to fix an irregular heartbeat (atrial fibrillation). It uses a special MRI to see how well each method works.
Barcelona, CataloniaAges 18 years+ - NCT06220721Recruiting
Preventing long-term high blood pressure after preeclampsia
This trial is testing a medication called nifedipine (a long-acting blood pressure pill) to see if it can help lower the risk of long-term high blood pressure and improve blood vessel health after a pregnancy complication like preeclampsia. It is for women who have just given birth and are still in the hospital.
Chicago, IllinoisAges 18 years+ - NCT06222099Recruiting
Heartfelt study for chronic heart failure with swelling and adherence challenges
This trial tests a program to help people with chronic heart failure who have swelling in their feet and legs and struggle to follow their care plan. It aims to reduce hospital visits by improving daily monitoring and medication use.
Little Rock, ArkansasAges 22 years+ - NCT06222762Recruiting
Personalized exercise follow-up for chronic heart failure
This study tests whether a personalized exercise program can help people with chronic heart failure feel better and stay active. It is for patients who are already in a cardiac rehab program and have stable heart failure.
BrestAges 18–80 - NCT06223217Recruiting
New quality-of-life survey for leg artery disease patients
This study tests a new questionnaire (modified VascuQol) to measure how leg artery disease affects your daily life. It aims to create a better tool for doctors to track your symptoms and well-being.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT06223529Recruiting
Music therapy for arm weakness after stroke
This study tests whether listening to music can help improve arm movement after a stroke. You will have EEG brain scans during music sessions to see how your brain responds.
Bedford, BedfordshireAges 18–110 - NCT06223633Recruiting
Stent for sudden heart artery tears
This trial tests a special covered stent (a small mesh tube) for treating sudden tears in heart arteries or bypass grafts. If you have a perforation in a vessel of a certain size, this stent may help seal it and stop bleeding.
Dallas, TexasAges Any age - NCT06223906Recruiting
Heart valve disease marker study
This study will collect information and blood samples from people with heart valve disease to find biological markers that may help doctors better understand and treat the condition in the future.
Beijing, Beijing MunicipalityAges 18–100 - NCT06224426Recruiting
Oxygen Levels for Stroke Patients Having Clot Removal
This trial tests whether giving a specific level of oxygen during a procedure to remove a stroke clot improves recovery. It is for people with a moderate to severe stroke in the front part of the brain, treated within 24 hours of symptoms starting.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06224517Recruiting
Artery health after stroke and rehabilitation
This study looks at how well your arteries are working after a stroke and how rehabilitation may help. It uses a simple, painless test (pulse wave velocity) to check artery stiffness.
TaipeiAges 18–80 - NCT06225544RecruitingPhase 2
Lumasiran for high oxalate patients on hemodialysis
This trial tests a drug called Lumasiran to lower oxalate levels in patients on hemodialysis (a type of kidney dialysis). It may help reduce complications from high oxalate, which can damage organs.
BerlinAges 18–80 - NCT06225310RecruitingPhase 1
New combo for relapsed/refractory multiple myeloma
This trial tests a three-drug combination (selinexor, ruxolitinib, and methylprednisolone) for people with multiple myeloma that has come back or stopped responding after at least three prior treatments. The goal is to see if this new combination can help control the cancer.
West Hollywood, CaliforniaAges Any age - NCT06225752RecruitingPhase 3
Probucol for recent stroke or mini-stroke from narrowed arteries
This study tests whether the drug probucol can help people who recently had a stroke or mini-stroke caused by a narrowed artery in the brain or neck. It aims to reduce the risk of future strokes.
WuhuAges 40 years+ - NCT06226493Recruiting
Vagus Nerve Stimulation for Stroke Recovery
This early-stage study tests if putting a mild electrical pulse on the vagus nerve (a nerve in the neck) can help the brain heal after a first-time stroke. It looks for changes in brain activity and certain DNA markers to understand how the treatment works.
Pomona, CaliforniaAges 18–80 - NCT06226805RecruitingPhase 2
Testing BB-031 for recent ischemic stroke
This study tests an experimental drug called BB-031 to see if it can safely help people who have had a recent ischemic stroke (a clot that blocks blood flow to the brain). The trial is for people who can get to the hospital within 24 hours of their first symptoms and have a moderate to severe stroke.
Scottsdale, ArizonaAges 18 years+ - NCT06227468Recruiting
Mapping immune system genes in Greek adults
This study maps immune system genes (HLA) in Greek adults. It uses a simple cheek swab sample to collect data, with no experimental treatment.
Chaïdári, AtticaAges 18 years+ - NCT06227754Recruiting
OCT vs. angiography for heart attack treatment
This trial compares two ways to guide treatment during a heart attack: using a special camera (OCT) inside the artery or standard X-ray (angiography). It aims to see which method leads to better results for patients.
Daegu, DaeguAges 19 years+ - NCT06228924RecruitingPhase 1
Gene therapy for ARVC with PKP2 mutation
This trial tests a new gene therapy called TN-401 for people with ARVC caused by a specific PKP2 gene mutation. The goal is to see if the treatment is safe and can help reduce dangerous heart rhythms.
San Francisco, CaliforniaAges 18–65
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.