Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06228456RecruitingPhase 4
Low-dose ticagrelor vs clopidogrel for stable heart patients after stent
This trial tests whether a lower dose of the blood thinner ticagrelor works better than clopidogrel in people with stable coronary artery disease who are getting a planned stent. It aims to find which drug is safer and more effective for preventing future heart problems.
Jacksonville, FloridaAges 18 years+ - NCT06228794Recruiting
CPC blood test to predict multiple myeloma outcomes
This trial is studying a new blood test that measures circulating plasma cells (CPCs) to help predict how multiple myeloma may progress. It is for people newly diagnosed with multiple myeloma who have not yet started treatment.
Wuhan, HubeiAges 18–80 - NCT06229171Recruiting
Digital health tool for heart medication support
This study tests a personalized digital tool (like a smart speaker) to help people remember to take their blood pressure medications correctly. It is designed for adults with high blood pressure who already take at least one blood pressure pill.
MilanAges 18 years+ - NCT06229418Recruiting
Testing drone delivery of AEDs for rural cardiac arrests
This study is testing whether drones can deliver AEDs (devices that restart a stopped heart) more quickly to people having a cardiac arrest in rural areas. It looks at people whose heart stopped before emergency help arrived and who received a shock from a bystander's AED.
Clemmons, North CarolinaAges 18 years+ - NCT06230406Recruiting
Gene study in atherosclerosis patients having surgery
This study looks at genes in people who have atherosclerosis (hardening of the arteries). It will check tissue samples taken during surgery to learn more about how the disease works.
San Donato Milanese, MilanAges Any age - NCT06230718Recruiting
Thinking about moving your arm after stroke
This study tests if thinking about moving your arm (motor imagery) and watching a video of arm movements can help you move better after a stroke. It uses a technique called EMG to measure muscle signals while you try or imagine moving.
Salamanca, SalamancaAges 18–99 - NCT06231966Recruiting
High-dose statin combo vs. standard statin for artery disease
This trial compares a high-dose combination of rosuvastatin (a statin) and ezetimibe (another cholesterol-lowering drug) versus a standard rosuvastatin-only approach for people with peripheral artery disease (narrowed leg arteries) or widespread artery disease. The goal is to see which strategy better lowers LDL cholesterol and reduces heart and limb risks.
SeoulAges 19–80 - NCT06231810Recruiting
Tracking touch signals in the nervous system
This study measures how your body processes a touch signal from your hand to your brain. It compares healthy young adults and people with stroke to understand how the nervous system changes after a stroke.
Blacksburg, VirginiaAges 18 years+ - NCT06232096RecruitingPhase 1/Phase 2
Study of MBS314 for relapsed or refractory multiple myeloma
This trial tests a new drug called MBS314 for people whose multiple myeloma has returned or stopped responding to other treatments. The goal is to see if MBS314 can help shrink or control the myeloma.
BeijingAges 18 years+ - NCT06232551Recruiting
Hospital alert to prescribe rivaroxaban to prevent blood clots
This trial tests whether alerting your hospital doctor to prescribe a blood thinner called rivaroxaban (Xarelto) at discharge can help prevent dangerous blood clots in your legs or lungs. It is for patients who are at higher risk for clots but have a low bleeding risk.
Murray, UtahAges 18–110 - NCT06233682Recruiting
Enriched environment for stroke recovery
This study tests whether an enriched environment in a hospital ward can help people recover after a stroke. It looks at whether adding more activities and social interaction to your daily routine can improve your recovery.
PadovaAges 18 years+ - NCT06234332Recruiting
Peking University Birth Cohort in Weifang
This study follows pregnant women and their families in Weifang to learn about health during pregnancy, birth, and early childhood. If you join, you, your husband, and your baby will be part of a long-term research project that tracks your health and development.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06234124Recruiting
A shoe to improve walking after stroke
This study tests a special shoe that changes friction to help improve walking for people who have had a stroke. It lasts 6 months and involves daily exercises at home.
Chicago, IllinoisAges 18 years+ - NCT06234410Recruiting
Heart risk check before kidney transplant
This study uses a special heart CT scan (called coronary angiography) to check the heart health of people waiting for a kidney transplant. It aims to see if this scan can help doctors better assess and manage heart risks before surgery.
Edinburgh, LothianAges 16 years+ - NCT06235112Recruiting
AI Screening for Heart Calcium from Chest CT Scans
This research study uses an artificial intelligence program to screen old chest CT scans for calcium buildup in the heart arteries. If you are between 40 and 75 and have had a chest CT in the last 3 years, this may help identify if you are at risk for heart disease so you can take steps to prevent it.
Boston, MassachusettsAges 40–75 - NCT06235229RecruitingPhase 1/Phase 2
GC012F for relapsed/refractory multiple myeloma
This trial tests a new CAR-T cell therapy called GC012F for multiple myeloma that has come back or not responded to at least three prior treatments. It aims to see if this treatment can help control the disease.
BeijingAges 18–75 - NCT06235385Recruiting
European study on multiple and mixed valve disease
This study looks at people with multiple or mixed heart valve disease (moderate or severe) using echocardiography. It aims to learn more about how these conditions affect patients and help guide future care.
Paris, Île-de-France RegionAges 18 years+ - NCT06235619Recruiting
Aortic arch size study
This study looks at the shape and size of the aortic arch (the main artery from your heart) using CT scans. It helps doctors better understand normal variations in anatomy.
Milan, ItalyAges birth–100 years - NCT06236022RecruitingPhase 4
Sirolimus for dilated cardiomyopathy with KSHV infection
This trial tests whether the drug sirolimus (rapamycin) can help people with dilated cardiomyopathy who also have a specific virus (KSHV) in their blood. It aims to see if sirolimus can improve heart function.
Wuhan, HubeiAges 18–70 - NCT06236373Recruiting
Understanding cancer survivors' needs in Reggio Emilia
This study aims to understand the challenges and needs of people who have survived certain cancers (breast, prostate, thyroid, colorectal, multiple myeloma, or lymphoma) and their caregivers. It uses interviews or focus groups to gather perspectives.
Reggio Emilia, Reggio EmiliaAges 18 years+ - NCT06236568Recruiting
Liver transplant study for liver cancer patients
This study tests a special way to preserve donated livers before transplant to see if it reduces the chance of liver cancer coming back after surgery.
Modena, MOAges 18 years+ - NCT06236750Recruiting
Testing a human tissue wound covering for hard-to-heal ulcers
This study is testing a special wound covering made from donated human tissue (amnion/chorion membrane) to see if it helps heal stubborn diabetic foot ulcers or venous leg ulcers that haven't improved with standard care. The covering is placed on the wound to help it heal.
Kobe, HyōgoAges Any age - NCT06237621Recruiting
Using a special camera to check leg circulation
This study tests a special camera (SnapshotNIR) that takes pictures of blood flow in your legs while you move them into different positions. It may help doctors better understand your circulation and diagnose peripheral artery disease (PAD) without needles or dye.
San Antonio, TexasAges 35–99 - NCT06237803Recruiting
Blood sample collection for plasma cell disorders
This study is collecting blood samples from people with plasma cell disorders to help researchers learn more about these conditions. It may be a good fit if you haven't started treatment yet and are willing to donate samples.
MelbourneAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.