Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06263452RecruitingPhase 4
Beta-blockers and stress response study
This trial tests how beta-blockers affect your body's reaction to stress. You'll take a beta-blocker or placebo and then do a stress task, so researchers can measure inflammation and other responses.
Chapel Hill, North CarolinaAges 18–30 - NCT06263608Recruiting
Sleep apnea testing and treatment for atrial fibrillation patients
This study tests a new way to check and treat sleep apnea in people with atrial fibrillation (AF). If you have AF and symptoms, you may be able to join and get sleep tracking and treatment that could help both your heart and sleep.
EdegemAges 18 years+ - NCT06263920Recruiting
Study on late-onset epilepsy and its links
This study looks at people who had their first seizure or were diagnosed with epilepsy after age 18, and compares them to people with migraine. The goal is to understand what might be connected to epilepsy that starts later in life.
Preston, LancashireAges 18 years+ - NCT06264427Recruiting
Study of metabolism issues in Greenland
This study looks at the genes and physical traits of people in Greenland with type 2 diabetes or severe obesity. It aims to better understand these conditions to improve care.
Nuuk, SermersooqAges 18 years+ - NCT06264531RecruitingPhase 2/Phase 3
Bevacizumab for adults with symptomatic, untreatable brain AVMs
This trial tests a medication called bevacizumab (given as an IV infusion) to see if it can improve symptoms in people with brain arteriovenous malformations (AVMs) that cannot be treated with standard therapies. It is for those whose AVMs cause significant disability.
Paris, Île-de-France RegionAges 18 years+ - NCT06264570Recruiting
Personalized supplements for high homocysteine and cholesterol
This study tests a personalized approach based on your genes to choose the right natural supplements for people with high homocysteine and high LDL cholesterol. It aims to help lower these levels safely.
Novosibirsk, Novosibisk RegionAges 18–80 - NCT06264843Recruiting
Peripheral bypass quality check study
This trial is testing a new way to check the quality of leg bypass surgery while you're still in the operating room, using a special device. It may help ensure the bypass is working well right away, which could reduce the risk of future problems.
San Francisco, CaliforniaAges 18 years+ - NCT06265766Recruiting
Brain stimulation for stroke recovery study
This trial tests a type of brain stimulation (called cTBS) to help improve arm movement after a stroke. It is designed for people who have weakness in one arm due to a first stroke and can start treatment within 21 days.
's-HertogenboschAges 18 years+ - NCT06266065Recruiting
Heart vein device for chest pain not helped by medication
This trial tests a small device placed in a vein near the heart to improve blood flow and reduce chest pain in people who cannot have bypass surgery or stents. The device aims to increase the heart's oxygen supply and relieve symptoms.
ZagrebAges 18–90 - NCT06266845Recruiting
Escape room game for nurses learning heart rhythm problems
This trial tests whether a gamified escape-room exercise helps nursing students better identify heart arrhythmias in critically ill patients. It compares learning outcomes for students who already passed their adult health course.
Brasília, Federal DistrictAges 18 years+ - NCT06268041Recruiting
Walking recovery after stroke: high-intensity treadmill training
This trial tests if high-intensity treadmill training can improve walking speed for people who had a stroke at least 6 months ago. It focuses on those who still walk slowly and may use a walker or cane.
Newark, DelawareAges 30–85 - NCT06269679Recruiting
Comparing two dental x-rays one year after heart infection
This trial compares two types of dental X-rays (OPT and CBCT) to see which one better detects dental problems one year after a serious heart infection called infective endocarditis. It aims to help decide the best way to monitor your oral health after the infection.
BordeauxAges 18–100 - NCT06270316RecruitingPhase 1/Phase 2
Gene therapy for classic Fabry disease
This trial tests a new gene therapy called AMT-191 for men with classic Fabry disease who still have symptoms despite standard enzyme replacement therapy. It aims to see if the treatment is safe and can improve symptoms.
Birmingham, AlabamaAges 18–50 - NCT06270238Recruiting
Personalized brain stimulation to improve arm function after stroke
This trial tests whether a personalized, non-invasive brain stimulation treatment (rTMS) can help improve arm function in people who had a stroke within the past 3 months. It is designed for patients with moderate to severe arm weakness who are still in the hospital.
SeoulAges 19 years+ - NCT06270537Recruiting
Dominus stent-graft follow-up study
This study is checking how well the Dominus stent-graft works over time in people who have already had it placed. You may be asked to come back for follow-up visits.
Vila Velha, Espírito SantoAges 18 years+ - NCT06270459Recruiting
Robot-assisted arm rehab at home after stroke
This study tests whether using a robot at home, with help from a carer, can improve arm movement after a stroke. It's for adults 21 to 90 years old who had a stroke at least 28 days ago and have moderate arm weakness.
Singapore, SingaporeAges 21–90 - NCT06270498RecruitingPhase 4
Oral iron for heart failure: exercise and quality of life study
This study tests whether an oral iron supplement (a pill called sucrosomial iron) can help people with heart failure who have low iron feel better, have more energy, and walk farther. Participants will take the iron pill or a placebo (a pill without the active ingredient) for a period and will do exercise tests and answer questionnaires to see how they improve.
Pisa, TuscanyAges 18 years+ - NCT06270888RecruitingPhase 1
Shorter radiation treatment for multiple myeloma
This trial tests a shorter course of radiation therapy for up to 5 bone lesions that have come back or not responded to treatment. It aims to see if this approach is safe and helps control the disease.
Chicago, IllinoisAges 18 years+ - NCT06270667Recruiting
Exercise training for lymphoma survivors
This study tests whether a supervised exercise program can improve heart health in people who finished treatment for Hodgkin or aggressive non-Hodgkin lymphoma 2–5 years ago. The goal is to see if regular exercise helps your heart recover better after chemotherapy or chest radiation.
OsloAges 20–70 - NCT06271018Recruiting
Tocilizumab for Aortitis in Giant Cell Arteritis
This trial tests the drug tocilizumab (Actemra) to see if it helps reduce swelling in the aorta in people with giant cell arteritis (GCA) who are newly diagnosed or have had a flare. It may offer a targeted treatment for aortitis without using high-dose steroids.
ParisAges 18 years+ - NCT06271187Recruiting
Brace Therapy for Hand Recovery After Stroke
This study tests whether a custom brace (dynamic orthosis) combined with therapy can improve hand movement in people who had a stroke at least 3 months ago. It is designed for those whose arm has some recovery but still needs help with hand opening and grasping.
TainanAges 20–80 - NCT06271252RecruitingPhase 1
Study of OriCAR-017 for relapsed or refractory multiple myeloma
This trial tests a new type of CAR-T cell therapy called OriCAR-017 for people with multiple myeloma that has come back or not responded to treatment. It is for patients who have already tried several treatments, including ones that target BCMA, and their last treatment stopped working.
Atlanta, GeorgiaAges 18–75 - NCT06271577Recruiting
Smartphone ECG for heart attack detection
This study tests whether a smartphone can take a 12-lead ECG (a heart tracing) quickly when someone arrives at the ER with chest pain, to help doctors spot a heart attack sooner.
Rochester, MinnesotaAges 18 years+ - NCT06271590Recruiting
Drug-coated balloon for small heart artery blockages
This trial tests a special balloon coated with a drug (sirolimus) to treat blockages in small heart arteries. If the balloon is successful, it may help keep the artery open without needing a permanent stent.
Gilbert, ArizonaAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.