Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06509698Recruiting
Virtual reality vs. Frenkel's exercises for stroke recovery
This trial compares virtual reality (VR) exercises to traditional Frenkel's exercises to see which helps stroke survivors improve balance and movement. You might benefit if you've had an ischemic stroke and haven't tried VR rehab before.
Lahore, Punjab ProvinceAges 40–65 - NCT06509893RecruitingPhase 4
Ticagrelor alone after stent placement
This study tests if a single blood thinner (ticagrelor) works well enough after getting a heart stent, instead of the usual two blood thinners. It may simplify your daily medication routine.
Shiraz, FarsAges 20–80 - NCT06509646Recruiting
Tai Chi vs. Frenkel's exercises for stroke recovery
This study compares two types of gentle balance exercises (Tai Chi and Frenkel's exercises) to see which one helps people recover better after a stroke. It is for stroke survivors who are 50+ and at least 3 months past their stroke.
Lahore, Punjab ProvinceAges 50 years+ - NCT06510231Recruiting
Breathing muscle training for heart failure with preserved ejection fraction
This study tests whether breathing muscle training can improve exercise capacity and symptoms in people with a type of heart failure called HFpEF. You may qualify if you are already on certain heart medications and are stable enough to exercise.
Rochester, MinnesotaAges 18 years+ - NCT06510322RecruitingEarly Phase 1
Sildenafil for LVAD support
This trial tests whether sildenafil (the drug in Viagra) can help reduce blood vessel changes in people with a left ventricular assist device (LVAD). It aims to improve heart-pump function and overall health.
The Bronx, New YorkAges 18 years+ - NCT06510556Recruiting
Testing a new mapping and ablation system for AFib
This study tests a new device (FARAFLEX) that uses pulsed field energy to treat atrial fibrillation (AFib). You may qualify if you have persistent or paroxysmal AFib symptoms and have not had a prior ablation.
BrusselsAges 18 years+ - NCT06510491RecruitingPhase 2
Epcoritamab for relapsed Waldenstrom macroglobulinemia
This trial tests epcoritamab, an immunotherapy that helps your immune system attack cancer cells, for people with Waldenstrom macroglobulinemia (WM) whose disease has gotten worse or who couldn't tolerate previous treatments. It's for those who've already tried a BTK inhibitor (like ibrutinib or zanubrutinib) and an anti-CD20 antibody (like rituximab).
Boston, MassachusettsAges 18 years+ - NCT06510582RecruitingPhase 1/Phase 2
Bevacizumab injection for chronic subdural hematoma
This trial tests if injecting bevacizumab into the artery that supplies the covering of the brain can help treat chronic subdural hematoma (a slow-growing collection of blood on the brain's surface). It may offer an alternative to surgery for some patients.
Camden, New JerseyAges 18 years+ - NCT06510998Recruiting
Handgrip exercise for lowering blood pressure
This trial tests if simple handgrip exercises (a type of isometric resistance exercise) can help lower blood pressure in people with high blood pressure. It compares the exercise group to a control group to see if this easy activity can improve heart health.
Hong KongAges 18 years+ - NCT06511089RecruitingPhase 3
Carotid artery stenting during stroke clot removal
This trial tests whether placing a stent in a narrowed carotid artery during a procedure to remove a stroke clot improves outcomes. If you have a stroke with a blocked large artery and significant carotid narrowing, this study may be relevant to you.
GroningenAges 18 years+ - NCT06511245Recruiting
Comparing WEB to other treatments for ruptured brain aneurysms
This trial compares a new device called WEB (a mesh-like implant) with other standard treatments for people who have a ruptured brain aneurysm. The goal is to see if WEB works as well or better than other options.
ReimsAges 18 years+ - NCT06511479Recruiting
Hypertension study for women in the Jackson Heart Study
This trial tests a program to help manage blood pressure in women who are already part of the Jackson Heart Study. You would join group sessions that are audio-recorded and receive support to improve your heart health.
Jackson, MississippiAges 18–99 - NCT06511934Recruiting
BrainGate2 tablet trial for tetraplegia
This trial tests a brain-computer interface (BrainGate2) system for people with tetraplegia (paralysis of all four limbs). It aims to see if the system can help you control a tablet computer using only your brain signals. This is for people who were already in the BrainGate2 study.
Boston, MassachusettsAges 18–80 - NCT06511999Recruiting
Measuring brain oxygen after cardiac arrest
This study tests a special sensor placed in a neck vein to continuously measure oxygen levels in the blood returning from the brain after cardiac arrest. The goal is to help doctors better understand and protect brain function during recovery in the ICU.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06512493Recruiting
South East Netherlands Heart Registry
This is a heart registry that collects information from all patients to get a complete picture of heart care in the region. By including everyone, it aims to improve future treatments without bias.
Heerlen, LimburgAges Any age - NCT06512870Recruiting
Detecting perfusion problems in leg injuries
This trial tests two devices to see if they can quickly detect when a leg muscle is not getting enough blood after a serious leg injury.
Gainesville, FloridaAges 18–75 - NCT06514170Recruiting
Stomach and bowel function after aortic surgery
This study looks at how stomach and bowel function changes after major aortic surgery. It may help doctors understand and prevent digestive problems in patients who need extended time on a ventilator after surgery.
Mexico City, TlalpanAges 18 years+ - NCT06513611Recruiting
Immune and hormone markers in acute coronary syndrome prognosis
This trial looks at how your body's immune system, hormones, and inflammation affect recovery after a heart attack or unstable angina. It may help doctors better predict outcomes for people with acute coronary syndrome.
Buenos AiresAges 21 years+ - NCT06513975Recruiting
Validation study of a wearable cuffless blood pressure monitor
This study tests a new wearable device that measures blood pressure without a cuff. You might be able to join if you are generally healthy, not pregnant, and have no serious heart or kidney problems.
SeoulAges 18–80 - NCT06514508RecruitingPhase 3
Stem cell collection with motixafortide and G-CSF for multiple myeloma
This trial tests a new drug, motixafortide, combined with a standard growth factor (G-CSF) to help collect stem cells for a transplant in people with multiple myeloma. It may be a good option if your myeloma is in remission and you have not had a stem cell transplant before.
Beijing, Beijing MunicipalityAges 18–78 - NCT06514976Recruiting
Study of Cytoflavin for ischemic stroke without clot treatment
This study is testing a medicine called Cytoflavin for people who have had a recent ischemic stroke but are not receiving clot-busting treatment. It aims to see if Cytoflavin helps improve recovery compared to other treatments or no treatment.
IvanovoAges 18 years+ - NCT06515093Recruiting
New skin grafts for diabetic foot and venous leg ulcers
This study tests two new skin graft products (PelloGraft for diabetic foot ulcers and SanoGraft for venous leg ulcers) to see if they heal wounds faster than standard care. If you have a hard-to-heal foot or leg ulcer, this trial may offer a new option.
Vista, CaliforniaAges 18 years+ - NCT06515249Recruiting
Integrative therapies for multiple myeloma
This trial offers integrative therapies like acupuncture and reflexology to people with multiple myeloma. It aims to see if these treatments can help improve well-being and manage symptoms.
HaifaAges 18 years+ - NCT06515262Recruiting
Testing anti-BCMA-GPRC5D CAR-T cells for relapsed multiple myeloma
This trial tests a new type of cell therapy (CAR-T cells) that targets two proteins, BCMA and GPRC5D, on myeloma cells. It aims to see if it is safe and effective for people whose multiple myeloma has come back or stopped responding to at least three previous treatments.
Kunming, Kunming, YunnanAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.