Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT05809323Recruiting
Trial testing moderate exercise in teens with Marfan syndrome
This trial studies whether doing moderate exercise is safe and helpful for people with Marfan syndrome. It aims to see how exercise affects heart and health measures, like how the aorta and body respond over time.
Houston, TexasAges 10–25 - NCT04330729Recruiting
Aspirin effect on blood clotting in kidney disease
This study checks how aspirin (also called salicylate) affects how platelets work, which helps blood clot. It involves people with advanced chronic kidney disease who are treated with Aranesp, and it may help guide safer care.
RoskildeAges 18–85 - NCT05306834Recruiting
Study to slow memory decline by targeting hidden small brain vessel disease
This trial looks at how to slow cognitive decline and early dementia in people with a specific kind of “silent” blood vessel damage in the brain seen on scans. It may help identify whether targeting this hidden condition can protect thinking and memory over time.
BordeauxAges 60–88 - NCT04715425Recruiting
Surgery vs catheter procedure for persistent atrial fibrillation
This trial compares two ways to treat persistent atrial fibrillation: a minimally invasive surgery approach versus a catheter ablation. It may help people find the most effective option to reduce ongoing abnormal heart rhythm and avoid repeat procedures.
AmsterdamAges 18–80 - NCT04776642Recruiting
Biobank for heart rhythm disorders and conduction problems
This study builds a biobank (a secure collection of medical information and body samples) for people with certain heart rhythm problems. You may be able to contribute to research that helps improve understanding and treatment of these conditions.
AmsterdamAges 18 years+ - NCT06223217Recruiting
New quality-of-life survey for leg artery disease patients
This study tests a new questionnaire (modified VascuQol) to measure how leg artery disease affects your daily life. It aims to create a better tool for doctors to track your symptoms and well-being.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT07864389Recruiting
Monitoring brain aneurysms that have not burst
This study looks at a new way to check on brain aneurysms that have not burst and are not causing symptoms. It may help doctors decide if or when treatment is needed, using regular imaging instead of surgery.
NantesAges 18 years+ - NCT05424978Recruiting
Standardized green-channel treatment for acute stroke care
This study tests a structured, fast way of treating people who have a new ischemic stroke (a stroke caused by a blocked blood vessel). It may help because it focuses on getting the right stroke treatments quickly and consistently.
Xi'an, ShaanxiAges 18–100 - NCT06218199RecruitingPhase 4
Diuretics vs. blood pressure meds for HeartLogic alerts
This trial compares two treatments—diuretics (water pills) and a blood pressure medication called sacubitril/valsartan—to see which works better when your heart device sends an alert. It's for people with a Boston Scientific heart device that has HeartLogic alerting turned on.
Huntsville, AlabamaAges 19 years+ - NCT06223906Recruiting
Heart valve disease marker study
This study will collect information and blood samples from people with heart valve disease to find biological markers that may help doctors better understand and treat the condition in the future.
Beijing, Beijing MunicipalityAges 18–100 - NCT02453919Recruiting
Study of heart complications in people living with HIV
This study looks back at people with HIV to understand how often and why heart problems happen. It may help doctors better track heart risk and complications over time.
ParisAges 18 years+ - NCT07871188Recruiting
Blood pressure swings and recovery after heart bypass surgery
This study looks at how changes in blood pressure during heart bypass surgery relate to how quickly the body clears lactic acid afterwards, which is a sign of recovery. It may help doctors understand recovery patterns after surgery.
GaziantepAges 18–80 - NCT07864129Recruiting
Pulmonary artery growth after tetralogy of Fallot surgery
This study looks at how the pulmonary arteries (the blood vessels that carry blood from the heart to the lungs) develop in children who had surgery for tetralogy of Fallot, a heart condition present at birth. It aims to learn more about normal growth patterns, which could help doctors better care for other children with similar heart problems.
StrasbourgAges birth–18 years - NCT07869069Recruiting
Mobile heart health visits for remote communities
This study brings heart health checkups to Indigenous and remote communities using a mobile health unit. It aims to improve heart disease prevention and make healthcare more accessible.
Québec, QuebecAges 35–65 - NCT07860840Recruiting
Visual training before robot-assisted walking for stroke survivors
This study tests whether a special visual training program before using a walking robot can improve walking recovery in people who have had a stroke or similar brain injury within the last 6 months and have trouble sensing their affected side. If you join, you might get this extra visual practice to help your brain relearn movement.
Negrar, ItalyAges 18–80 - NCT05243212RecruitingPhase 1/Phase 2
CAR-T cell therapy for multiple myeloma
This Phase 1/2 study tests a personalized CAR-T cell treatment that targets a protein called BCMA on myeloma cells. It’s designed for people with multiple myeloma who have already tried several other treatments and still have measurable disease.
Ramat GanAges 18 years+ - NCT03225586Recruiting
Study of health differences in urban and rural communities
This study enrolls consenting adults to understand how health differs between people living in cities versus rural areas. Your participation may help researchers learn what factors influence health over time.
Rosario, Santa Fe ProvinceAges 35–70 - NCT04375306Recruiting
Testing a heart-pressure ratio to choose bypass surgery plan
This trial studies whether a special heart “pressure/flow ratio” test (measured during the procedure) can help doctors choose the best plan for coronary bypass surgery. It may improve how bypass targets the problem blood vessels, but only if certain heart and health factors fit the study rules.
BonheidenAges 18 years+ - NCT05649670Recruiting
Compare starting stroke clot-busting before vs after hospital
This study tests whether starting clot-busting treatment by the emergency team before hospital arrival works better than starting it after you reach the hospital. It may help doctors improve speed and outcomes after an acute stroke.
GarchesAges 18 years+ - NCT05292651Recruiting
Stent placement strategy study for blocked heart arteries
This study compares how best to place a coronary stent (a small tube to keep an artery open) using modern techniques. It may help improve how safely and effectively stents are delivered in people with certain types of narrowed heart arteries.
DordrechtAges 18–100 - NCT05860894Recruiting
Study of new ICU atrial fibrillation
This trial looks at people who develop a new irregular heart rhythm called atrial fibrillation while in the intensive care unit (ICU). It tests an approach to help with that condition after critical illness, aiming to improve outcomes for those affected.
BesançonAges 18 years+ - NCT06236022RecruitingPhase 4
Sirolimus for dilated cardiomyopathy with KSHV infection
This trial tests whether the drug sirolimus (rapamycin) can help people with dilated cardiomyopathy who also have a specific virus (KSHV) in their blood. It aims to see if sirolimus can improve heart function.
Wuhan, HubeiAges 18–70 - NCT06236750Recruiting
Testing a human tissue wound covering for hard-to-heal ulcers
This study is testing a special wound covering made from donated human tissue (amnion/chorion membrane) to see if it helps heal stubborn diabetic foot ulcers or venous leg ulcers that haven't improved with standard care. The covering is placed on the wound to help it heal.
Kobe, HyōgoAges Any age - NCT03197350Recruiting
Study of heart failure with preserved pumping function
This study looks at people who have heart failure symptoms but whose heart pumping strength is not reduced. Researchers aim to better understand this type of heart failure and compare it with people who have no history of heart disease or heart failure.
BrusselsAges 18–99
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.