Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06784440Recruiting
Finding noninvasive markers of graft injury after heart transplant
This study looks for noninvasive markers (like blood or urine tests) that can show if a heart transplant is being injured. It aims to make monitoring safer and easier for children and adults with congenital heart disease who have had a transplant.
BolognaAges Up to 44 years - NCT06784466Recruiting
New ablation procedure for atrial fibrillation
This study is testing a new type of ablation procedure for atrial fibrillation (an irregular heart rhythm). It uses special energy to create scar tissue in the heart to block faulty electrical signals. If you have AF that isn’t controlled by medication, you may qualify.
Birmingham, AlabamaAges 18–80 - NCT06784895Recruiting
Women-only cardiac rehab program
This trial tests a cardiac rehab program designed just for women. It aims to see if a women-only setting helps with recovery after heart problems or procedures.
Ann Arbor, MichiganAges 40–80 - NCT06785116RecruitingPhase 4
Study on dapagliflozin for heart health after a hypertensive pregnancy
This trial tests a medicine called dapagliflozin (DAPA) to see if it reduces heart risk in women who had high blood pressure or preeclampsia during pregnancy. It is designed for those who had severe blood pressure rises around delivery or a high BNP level, a marker of heart strain.
Ann Arbor, MichiganAges 18 years+ - NCT06785181Recruiting
Heart-brain health in healthy adults
This study looks at how the heart, blood vessels, and brain work together in healthy adults. It may help us understand normal body function.
San Donato Milanese, MilanoAges 18 years+ - NCT06785415RecruitingPhase 1/Phase 2
Study of a drug combo for relapsed multiple myeloma
This trial tests a combination of two antibody drugs (elotuzumab and daratumumab) plus an oral pill (iberdomide) and a steroid (dexamethasone) for people whose multiple myeloma has come back after treatment. The goal is to see if this new mix works better than what's already available.
Rochester, MinnesotaAges 18 years+ - NCT06785506Recruiting
Personalized heart failure treatment using multiple biomarkers
This trial tests if using a combination of biomarkers can help personalize treatment for people with a specific type of heart failure called HFpEF (or heart failure with preserved ejection fraction). It aims to find better treatments based on your individual test results.
Alkmaar, North HollandAges 18 years+ - NCT06785740Recruiting
Statins for older stroke patients with frailty
This study looks at how well statins work in older stroke or TIA patients who are already taking them and also have some frailty. The goal is to understand if continuing statins is safe and helpful for this group.
Almere StadAges 70–120 - NCT06786000Recruiting
Brain stimulation plus hand therapy for stroke recovery
This trial tests a combination of mild electrical brain stimulation and a special hand therapy program to help improve arm and hand movement after a stroke. It is for adults who had a stroke more than three months ago and still have moderate to mild arm weakness.
Riyadh, Riyadh RegionAges 18 years+ - NCT06786364Recruiting
Measuring blood flow waves in sepsis patients
This study uses a special light sensor to measure blood flow waves in patients with septic shock. The goal is to see if these waves can help doctors understand how severe the shock is.
Mexico City, CuauhtemocAges 18 years+ - NCT06786416Recruiting
Monitoring to prevent kidney injury after heart surgery
This trial is testing a new monitoring system that tracks blood flow and other vital signs during heart surgery to help prevent kidney damage afterward.
San Donato Milanese, MilanoAges 18 years+ - NCT06786858Recruiting
Hand exoskeleton training for stroke recovery
This study tests whether a robotic hand device (exoskeleton) can help people who had a stroke more than 6 months ago improve hand movement. It may benefit those who still have some hand function but struggle to open their affected hand.
Washington D.C., District of ColumbiaAges 21 years+ - NCT06787482RecruitingPhase 1/Phase 2
Peptide therapy for retinitis pigmentosa
This trial tests a new peptide therapy for people with retinitis pigmentosa (RP), a genetic eye disease that causes vision loss. The goal is to see if the treatment is safe and can help slow or improve vision loss.
CairoAges Any age - NCT06788275Recruiting
Can exercise improve blood vessel health after a heart attack?
This study looks at whether aerobic exercise can improve blood vessel health in people who have had a heart attack or chest pain (angina). If you qualify, you'll join a monitored exercise program.
Alicante, AlicanteAges 45–75 - NCT06788314RecruitingPhase 2
Enalapril for painful venous malformations
This trial tests if the blood pressure drug enalapril can reduce pain from venous malformations (abnormal veins). It may help people whose pain limits daily activities or interrupts sleep.
Oslo, NorwayAges 18–70 - NCT06788431RecruitingEarly Phase 1
Study of IMC-001 to stabilize heart artery plaque
This trial tests an investigational drug, IMC-001, to see if it can make artery plaques in the heart more stable and less likely to cause a heart attack. You may be eligible if you've recently had a heart attack or unstable angina and have a specific type of soft plaque in your arteries.
Nanyang, HenanAges 18–75 - NCT06789003Recruiting
Prehabilitation with exercise for multiple myeloma patients
This trial tests whether a prehabilitation program using adapted physical activity can help multiple myeloma patients prepare for a stem cell transplant. It may improve your strength and recovery before and after the transplant.
AvignonAges 18 years+ - NCT06789211Recruiting
Outcomes in moderate mixed aortic valve disease
This study looks at people with a combination of moderate aortic stenosis and regurgitation, comparing them to those with severe aortic valve problems. It aims to understand outcomes and help guide treatment decisions.
Leiden, South HollandAges 18 years+ - NCT06789809Recruiting
Exercise and Aortic Aneurysm Study
This study looks at how exercise affects people with aortic aneurysms and how the aorta's structure relates to its function. You may join if you have an aortic aneurysm and are being monitored or scheduled for surgery, or if you are a healthy person for comparison.
Cleveland, OhioAges 18 years+ - NCT06789978Recruiting
Quick ECPR for cardiac arrest in Prague
This study tests a rapid way to give life support using a heart-lung bypass machine (ECPR) to people experiencing a sudden cardiac arrest that doesn't stop with defibrillators or standard CPR. The goal is to start this treatment within 20 minutes of the emergency call, which may improve chances of survival.
Prague, CzechiaAges 18–70 - NCT06790836Recruiting
CT scan vs. invasive test for heart artery blood flow
This study looks at how well a special CT scan (FFR CT) matches the results of a more invasive wire test (invasive FFR) for measuring blood flow in heart arteries. It may help doctors use CT scans more confidently instead of always needing the invasive procedure.
Birmingham, West MidlandsAges 18 years+ - NCT06791551Recruiting
Non-drug therapy before heart surgery to protect the brain
This study tests whether a simple, non-drug, non-surgical program before heart surgery can help protect your brain. It is for people with heart disease who are at higher risk for problems like stroke after surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06791681RecruitingEarly Phase 1
ESO-T01 for returning or hard-to-treat multiple myeloma
This trial tests a new treatment called ESO-T01 for people with multiple myeloma that has come back or is not responding to at least two prior therapies. It aims to see if this therapy is safe and can help control the disease.
Wuhan, HubeiAges 18 years+ - NCT06791915Recruiting
Comparing breathing method during heart ablation for AFib
This trial studies two ways of using a breathing machine during a heart procedure called radiofrequency ablation for atrial fibrillation (AFib). It aims to find which method is better and safer.
KocaeliAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Mental health
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- Immune system & allergy
- Women’s health & pregnancy
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.