Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06777368Recruiting
Redo TAVR for failed transcatheter aortic valves
This trial tests a second transcatheter aortic valve replacement (TAVR) procedure for patients whose first TAVR valve is failing. It focuses on structural problems inside the valve, not leakage around it.
Birmingham, AlabamaAges 18–105 - NCT06777771Recruiting
Reformer Pilates for first-time pregnant women
This trial tests if Reformer Pilates (a type of exercise using a special machine) helps first-time pregnant women stay healthy. If you are in your first pregnancy and between 11 and 22 weeks along, this may be a good fit for you.
Izmir, KonakAges 18–35 - NCT06777901RecruitingPhase 4
Laser plus balloon vs. balloon alone for leg artery blockages
This study compares using a laser device (Auryon) plus balloon angioplasty versus balloon angioplasty alone to open blocked arteries in the lower leg. The goal is to improve blood flow and reduce pain or heal sores in people with advanced peripheral artery disease.
Phoenix, ArizonaAges Any age - NCT06777927Recruiting
Exergaming training for people with high blood pressure
This study tests whether playing interactive video games (exergaming) can help people with high blood pressure get active and improve their health. It is for adults who have not exercised in the last 3 months.
Islamabad, FederalAges 20–55 - NCT06778239Recruiting
Childhood high blood pressure natural history study
This study follows children and young adults who have high blood pressure that started in childhood. It aims to understand why some kids develop high blood pressure without a clear cause, by looking at their genes, family history, and health over time. Participants will provide samples and medical information to help researchers learn more.
Bethesda, MarylandAges 2–99 - NCT06779110Recruiting
OCT vs. X-ray guidance for treating re-blocked stents
This study compares the standard X-ray guidance (angiography) with a more detailed imaging test (OCT) to guide treatment for a re-blocked stent. It aims to see which method leads to better outcomes for patients with in-stent renarrowing.
Aosta, AostaAges 18–99 - NCT06779513Recruiting
New EKG score to detect heart stiffness in high blood pressure
This study tests a new scoring method using your heart's electrical signals (EKG) and imaging to detect early stiffness of the heart's main pumping chamber, which often goes unnoticed in people with high blood pressure. If you have high blood pressure and no other major heart or kidney problems, you may be able to join.
Semarang, Central of JavaAges 18–70 - NCT06779552Recruiting
Study of CardioMEMS System for Heart Failure Patients
This study is looking at how well the CardioMEMS heart monitor works for people with heart failure. The device is already implanted and tracks pressure in your lung artery to help your doctor manage your condition and potentially prevent hospital visits.
Pleasanton, CaliforniaAges 18 years+ - NCT06779799Recruiting
Study of vocal cord lesions in autoimmune disease patients
This study examines vocal cord lesions, like 'bamboo' nodes, that cause voice changes (dysphonia) in people with autoimmune diseases such as lupus or rheumatoid arthritis. It aims to better understand and characterize these lesions to improve diagnosis and treatment.
BrestAges 18 years+ - NCT06780241Recruiting
Sex differences in valvular heart disease
This study uses special MRI scans to look at how valvular heart disease (like leaky or narrowed aortic valves) affects men and women differently. It aims to find unique biological patterns that could lead to better treatments.
Cleveland, OhioAges 18–90 - NCT06780462RecruitingPhase 3
Steroids with or without blood thinners for Behçet's vein clots
This trial tests whether adding a blood thinner (anticoagulant) to steroid therapy is more effective than steroids alone for treating deep vein thrombosis (a blood clot in a large vein) in people with Behçet's syndrome. It aims to find the best way to prevent future clots and reduce side effects.
BordeauxAges 18 years+ - NCT06780488Recruiting
Virtual reality balance training for stroke recovery
This trial tests whether a special virtual-reality system that combines head movements and balance exercises can help improve walking and stability for people who have had a stroke. It is designed for those who are at least 6 months past their stroke and can walk with some help.
Roma, RMAges 18–80 - NCT06780514Recruiting
Exercise testing for girls with Turner syndrome
This study will have girls with Turner syndrome do a cardiopulmonary exercise test (a special bike or treadmill test) to check how their heart and lungs work during exercise. It may help doctors better understand fitness and health in Turner syndrome.
GhentAges 8–18 - NCT06780722Recruiting
Study of heart and blood circulation issues during a specific organ donation process
This trial is studying heart and blood circulation problems that may happen during a certain type of organ donation (called Maastricht 3). It is for people who donate organs and those who receive them. The goal is to see how the level of oxygen in the blood affects these problems.
AngersAges 18 years+ - NCT06780995Recruiting
Power exercise for better walking after stroke
This study tests if a power-based exercise program can improve walking and overall recovery for people who had a stroke at least six months ago. It may help you move more easily and feel stronger.
Kelowna, British ColumbiaAges 19 years+ - NCT06781892Recruiting
Defibrillation strategies for cardiac arrest outside the hospital
This trial tests different ways of using defibrillators to restart the heart in people who have a cardiac arrest outside a hospital. It compares two defibrillator machines used together to see if one approach works better for shockable heart rhythms.
AalborgAges 18 years+ - NCT06782100Recruiting
MRI-Guided Treatment for Severe Leg Artery Blockages
This study uses MRI to guide treatment of blocked leg arteries below the knee, aiming to improve blood flow and reduce severe pain or sores.
Houston, TexasAges 18 years+ - NCT06782321Recruiting
Virtual emotional support after stroke
This study tests a virtual program to help with emotional recovery like anxiety or sadness after a stroke. You can join from home using your own device.
Charleston, South CarolinaAges 21 years+ - NCT06782464Recruiting
Freezing nerves for shoulder pain after stroke or brain injury
This trial tests if freezing certain nerves in the upper arm (cryoneurolysis) works as well as standard care for reducing shoulder pain and muscle tightness after a stroke or brain injury. It aims to improve function and ease caregiving tasks.
LuxembourgAges 18 years+ - NCT06782997Recruiting
Using a quick eye test to check for diabetes eye damage
This trial tests if a special eye exam (electroretinogram) done by a nurse can find early signs of diabetic retinopathy in people with diabetes who have no known eye problems yet. It aims to make screening easier and more accessible.
ReimsAges 18 years+ - NCT06783049Recruiting
Smartphone help to prevent another stroke after recent stroke or TIA
This trial tests a smartphone-based system that helps people who recently had a stroke or TIA manage their risk factors like high blood pressure or diabetes after leaving the hospital. It's designed to see if this tool can prevent another stroke.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06783335Recruiting
Cordella sensor for chronic heart failure
This trial studies a small sensor placed in the lung artery to help manage chronic heart failure. It compares patients who get the sensor to those who receive standard care, to see if the sensor improves outcomes.
Naperville, IllinoisAges 18 years+ - NCT06783816Recruiting
New immune cell therapy for blood cancers
This study tests a new type of CAR-T cell therapy designed to treat certain blood cancers (like leukemia, lymphoma, or multiple myeloma) that have come back or not responded to standard treatment. The cells are enhanced with IL-15 to help them work better.
Taiyuan, ShanxiAges Any age - NCT06784167Recruiting
Vaccine response after CAR-T for myeloma and lymphoma
This study looks at how well vaccines work in people with multiple myeloma or certain lymphomas after they receive CAR-T cell therapy. It aims to help doctors understand the best way to revaccinate patients to protect against preventable diseases.
Portland, OregonAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.