Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,022 recruiting studies in this area right now.
By phase
- Not applicable7,998
- Phase 2485
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure565
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)144
- Acute Ischemic Stroke141
- Pulmonary Hypertension102
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama198
- Massachusetts181
- Arizona176
- New York165
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,019 total
- NCT06793059Recruiting
Flow diverter device for large brain aneurysms
This trial tests a new device called a flow diverter to treat large or giant brain aneurysms in a specific part of the internal carotid artery. The device is designed to block blood flow into the aneurysm and may help prevent rupture or other complications.
Buffalo, New YorkAges 22 years+ - NCT06793449RecruitingPhase 2
BCMA CAR-T vs. stem cell transplant for multiple myeloma
This trial tests whether a newer immune treatment (BCMA CAR-T) works better than a stem cell transplant for people with multiple myeloma who are able to have a transplant. Both treatments aim to kill myeloma cells, but CAR-T uses your own engineered immune cells.
TianjinAges 18–70 - NCT06793670RecruitingPhase 4
Landiolol study for mitral valve surgery patients
This trial tests a short-acting beta-blocker called Landiolol given during mitral valve surgery to see if it helps the heart recover after surgery. It is for patients who have certain signs of heart strain before their operation.
Alessandria, PiedmontAges 18 years+ - NCT06793774Recruiting
Using CT scans and AI to evaluate heart artery risk
This study uses a CT scan of your heart (CCTA) and advanced computer analysis to see how well it can predict heart risks compared to detailed inside-look tests (IVUS, OCT, NIRS). If you have chest pain and have had certain heart scans, this trial may help doctors understand your condition better.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06793787Recruiting
AI and advanced imaging to guide treatment of borderline heart blockages
This study uses advanced CT scans and a special camera (OCT) to look at borderline blockages in heart arteries more closely. It aims to see if artificial intelligence can help decide which blockages need a stent and which can be treated with medicine alone.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06793839Recruiting
3D ultrasound imaging after brain bleed
This trial tests a new 3D ultrasound technique to see if it can better visualize blood flow in the brain after a subarachnoid hemorrhage (bleeding around the brain). It may help doctors monitor and treat patients more effectively.
CaenAges 18 years+ - NCT06793865Recruiting
Stimulation for ankle muscles to improve balance after stroke
This study tests a type of electrical stimulation, called Russian current, on the front shin muscles to see if it helps stroke patients stand steadier and lower their risk of falling.
MinyaAges 40–55 - NCT06793969Recruiting
New method to close PFO hole in heart
This trial is testing a new way to close a small hole in the heart (called a PFO) using a thin tube and a guidewire to make the procedure smoother. It's for people who have had a stroke or mini-stroke and whose PFO is thought to be the cause.
ShanghaiAges 18–65 - NCT06794008RecruitingPhase 2
CAR-T cell therapy for hard-to-treat autoimmune diseases
This trial tests a new treatment using your own immune cells (called CAR-T cells) designed to target and attack cells that cause autoimmune diseases. It is for people with lupus, Sjögren's syndrome, inflammatory myopathy, scleroderma, Behcet's disease, ANCA-associated vasculitis, IgG4-related disease, antiphospholipid syndrome, or thrombotic thrombocytopenic purpura who have not improved with standard therapies.
Beijing, Beijing MunicipalityAges 18–65 - NCT06794190Recruiting
Understanding liver health in Turner syndrome
This study aims to understand why some women with Turner syndrome develop liver problems. Researchers will analyze factors that may contribute to liver changes, which could lead to better monitoring and care.
BolognaAges 18 years+ - NCT06794684Recruiting
Watching Plaque in Heart Arteries Over Time
This study uses CT scans and special camera images inside your arteries to watch how plaque buildup in heart arteries changes over time. It may help you understand your risk and guide future treatment.
ShanghaiAges 18 years+ - NCT06794827Recruiting
Early access avacopan for ANCA vasculitis
This study looks at how well the drug avacopan works for people with a rare blood vessel disease called ANCA-associated vasculitis. It aims to help patients who are starting this treatment by tracking real-world results.
LeidenAges 16 years+ - NCT06795035Recruiting
Coronary microvascular testing after heart attack
This study tests a way to measure tiny blood vessels in the heart after a major heart attack (STEMI) using a special catheter with salt water. The goal is to see if this test helps doctors understand how well your heart is healing.
Cleveland, OhioAges 18 years+ - NCT06795152Recruiting
Rare GSD Natural History Study
This study follows people with rare types of glycogen storage disease (GSD) over time to learn more about how the disease progresses. It does not test a new treatment but will collect information to help future research.
Durham, North CarolinaAges birth–90 years - NCT06797154Recruiting
Stroke recovery study: wrist sensor to boost arm use
This study tests a wrist-worn sensor that vibrates to remind you to use your weaker arm. It's designed for people who had a stroke 1 to 6 months ago and have some arm weakness, to help them use their affected arm more during daily activities.
Boston, MassachusettsAges 18–85 - NCT06797687Recruiting
Studying the mitral valve with different scans before surgery
This study looks at how well CT scans and 3D echo (ultrasound) measure the mitral valve ring before surgery for severe mitral valve leakage. It may help doctors better plan valve repair.
RomaAges 18 years+ - NCT06797752Recruiting
Stellate ganglion block and retina blood flow study
This trial looks at how a nerve block (stellate ganglion block) affects blood flow in the retina. It may help people who already get this block for conditions like complex regional pain syndrome understand eye effects.
Dallas, TexasAges 18 years+ - NCT06797908Recruiting
High Blood Pressure in Children and Teens
This study looks at high blood pressure in children and teens. It aims to understand how to manage it in young people under 18.
Bologna, BolognaAges Up to 18 years - NCT06798155Recruiting
Music to prevent pain after anal surgery
This study tests whether listening to a specific set of music before and after surgery for hemorrhoids, fistula, or anal fissure can help reduce pain. You would use a phone or tablet app to listen to short music sessions.
Saint-DenisAges 18 years+ - NCT06798714RecruitingPhase 4
Colchicine to prevent irregular heartbeat after heart surgery
This trial tests whether the drug colchicine can reduce the chance of developing atrial fibrillation (an irregular heart rhythm) after open-heart surgery. If it works, it could help you recover more smoothly.
TomskAges 18 years+ - NCT06798740Recruiting
Study of brain aneurysm treatment with Sugita clipping devices
This study tracks people with brain aneurysms treated with a Sugita clipping device, watching how well it works and how they recover. It includes both ruptured and unruptured aneurysms, and follows standard care.
EssenAges 18 years+ - NCT06798766Recruiting
Understanding darker skin tones and vein disease care
This study looks at how people with darker skin tones experience chronic venous insufficiency (a condition that affects blood flow in the legs) and aims to improve how it's diagnosed and treated. It involves two parts: one is sharing your experience through an interview, and the other includes a skin check and photos at the hospital.
London, LondonAges 18 years+ - NCT06799026RecruitingPhase 1
Vaccine plus elranatamab for advanced multiple myeloma
This trial tests a personalized vaccine made from your own immune cells (dendritic cells) mixed with myeloma cells, given together with a drug called elranatamab. It is for people with multiple myeloma that has not responded to at least three prior treatments.
Boston, MassachusettsAges 18 years+ - NCT06799390Recruiting
Ear stimulation after brain bleed
This study tests whether gentle electrical stimulation through the ear (called auricular VNS) can help people recover after a bleed in the upper part of the brain. It aims to reduce inflammation and improve outcomes when started within 48 hours.
St Louis, MissouriAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,022 recruiting cardiology studies from the U.S. registry right now, out of 15,398 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.