Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT06951100Recruiting
Study of heart injury in rapid atrial fibrillation
This study looks at how a very fast heart rate from atrial fibrillation might affect the heart muscle. If you are having symptoms from this condition and haven't had a prior heart attack or stent, you may be able to help researchers understand the link and improve care.
Edinburgh, East of EnglandAges 18 years+ - NCT06951126Recruiting
CT prediction for tricuspid valve repair
This trial looks at how well a computed tomography (CT) scan can predict outcomes for people having a minimally invasive procedure to fix their tricuspid heart valve. If you are getting this procedure, your CT results will be studied to help improve future treatments.
Bad Oeynhausen, North Rhine-WestphaliaAges 18 years+ - NCT06951308Recruiting
Carb loading for type 2 diabetes before bypass surgery
This trial tests whether giving a carbohydrate drink before heart bypass surgery helps control blood sugar in people with type 2 diabetes. If it works, it could make recovery smoother.
DamascusAges Any age - NCT06951672Recruiting
Testing a new mitral valve repair device
This trial tests a new device called AMEND™ that is placed through a vein in the leg to repair a leaky mitral valve without open-heart surgery. It is for people with significant mitral regurgitation who are at high risk for surgery.
Phoenix, ArizonaAges 21 years+ - NCT06951724Recruiting
New device to remove blood clots during a heart attack
This trial tests a special catheter designed to suction out blood clots from the heart's arteries during a heart attack. It may help restore blood flow and limit heart damage.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06951867Recruiting
Tezspire heart safety study
This study looks at whether the asthma medicine Tezspire (tezepelumab) affects the risk of heart problems compared to other standard treatments for severe asthma. It will help doctors understand if Tezspire is safe for your heart.
Wilmington, DelawareAges 12–130 - NCT06952387Recruiting
Personalized blood pressure for high-risk surgery patients
This study tests whether personalized blood pressure management during and after major surgery can reduce complications and death in older adults with heart or blood vessel risks. It aims to find the safest blood pressure targets for each patient.
Guangzhou, GuangdongAges 65–90 - NCT06952374Recruiting
Shockwave balloon for severe mitral valve calcium
This trial tests a special balloon (Shockwave) to treat severe calcium buildup in the mitral valve. It may help people with tight valve opening who cannot have standard surgery.
Shatin, New TerritoriesAges 18 years+ - NCT06952348Recruiting
Stair climbing vs brisk walking for blood pressure
This study tests whether climbing stairs regularly can lower blood pressure better than brisk walking. It is for people who have high blood pressure, are overweight, and are not very active right now.
StockholmAges 35 years+ - NCT06952478RecruitingPhase 3
Comparing a new injectable multiple myeloma drug to Darzalex Faspro
This trial compares a new injectable medicine (CT-P44) to an approved one (Darzalex Faspro), both given with lenalidomide and dexamethasone, for people whose multiple myeloma has come back or stopped responding to treatment. It aims to see if the new option works just as well.
Taipei, Beitou DistrictAges 18 years+ - NCT06952543Recruiting
Ultrasound blood flow test for leg artery disease
This study uses ultrasound to measure blood flow in the legs of people with PAD symptoms and healthy volunteers. It aims to improve how doctors assess peripheral arterial disease without invasive tests.
Rochester, MinnesotaAges 18–75 - NCT06952933Recruiting
Trauma and resilience in adults with congenital heart disease
This study surveys adults with congenital heart disease to understand how psychological trauma and resilience affect their health. You would complete online questionnaires about your experiences and coping.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06952907Recruiting
Arm vs. leg artery pressure monitoring in heart surgery
This study compares measuring blood pressure through an arm artery (radial) versus a leg artery (femoral) during heart surgery that uses a heart-lung machine. The goal is to see which method works better and is safer for patients.
BesançonAges 18 years+ - NCT06953193Recruiting
Comparing anesthesia types for pancreas surgery
This study compares two types of anesthesia for people having pancreatoduodenectomy surgery. It tests whether adding an epidural to general anesthesia can help prevent low blood pressure during the operation.
Mexico City, Mexico CityAges 18 years+ - NCT06953180Recruiting
Epigenetics, aging, and disease prevention study in Kazakhstan
This study looks at how your genes and environment affect your risk for non-communicable diseases like heart disease or diabetes. It aims to predict your biological age and help create personalized prevention plans.
Almaty, KazakhstanAges 18–69 - NCT06953232Recruiting
Protein drink for heart and brain in midlife women
This study tests a special protein drink (whey with milk fat globule membrane) to see if it helps your heart and brain after a high-fat breakfast. It might help you if you are a postmenopausal woman at moderate risk for heart disease.
Loughborough, LeicestershireAges 50–75 - NCT06953622Recruiting
Migraine and PFO: A Follow-up Study
This study is for people who have migraines and a small hole in their heart called a patent foramen ovale (PFO). It will track your health over time to learn more about how these conditions are related.
BeijingAges Any age - NCT06953726RecruitingPhase 4
Comparing apixaban and rivaroxaban for atrial fibrillation
This study compares two common blood thinners, apixaban and rivaroxaban, in veterans with atrial fibrillation or flutter to see which one is safer and works better. If you are already taking one of these medicines, you may be able to join.
Miami, FloridaAges 65 years+ - NCT06953752Recruiting
Music during atrial fibrillation ablation under light sedation
This study tests whether listening to music during a common heart procedure for atrial fibrillation (called catheter ablation) can improve your experience while you are awake but relaxed. It may help you feel calmer and more comfortable.
Shaoxing, ZhejiangAges 18–80 - NCT06954103Recruiting
Stroke and heart health study for recent stroke patients
This study looks at how a moderate to severe stroke can affect your heart. It aims to understand the link between stroke and heart problems, which may help improve future care.
Wuhan, HubeiAges 18 years+ - NCT06954155RecruitingPhase 3
Tenecteplase for stroke treatment 24-72 hours after symptoms start
This trial tests if the clot-busting drug tenecteplase can help people with a moderate to severe stroke when given 24 to 72 hours after symptoms began. It aims to see if this later treatment window can improve recovery and reduce disability.
BeijingAges 18 years+ - NCT06954610Recruiting
Heart Check for Stroke Risk in Atrial Fibrillation
This trial uses heart imaging to better understand stroke risk in people with atrial fibrillation (an irregular heartbeat). It may help doctors decide on the best treatment to prevent another stroke.
BernAges 18 years+ - NCT06954714Recruiting
Balloon vs stent for new heart blockages
This trial compares two treatments for new blockages in heart arteries: a drug-coated balloon (a tiny balloon that delivers medicine) versus a drug-eluting stent (a small mesh tube that releases medicine). The study hopes to see which approach keeps the artery open longer and is safer over time.
Busan, BusanAges 19 years+ - NCT06954727Recruiting
Study on first-time right heart catheterization for lung blood pressure
This study is watching people who are having their first right heart catheterization to better understand and manage lung blood pressure problems. It may help doctors improve diagnosis and treatment for people with shortness of breath or suspected pulmonary hypertension.
BeijingAges 14 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.