Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT06448949Recruiting
Blood flow study after flow diverter for brain aneurysm
This study uses detailed 3D X-rays and ultrasound to understand how blood flows through a mesh tube (flow diverter) placed in a brain aneurysm. It may help doctors predict and prevent narrowing inside the tube.
Guangzhou, GuangdongAges 18 years+ - NCT06433050RecruitingEarly Phase 1
Testing a diabetes drug for nonobstructive hypertrophic cardiomyopathy
This trial tests a common diabetes drug (SGLT2 inhibitor) to see if it helps people with nonobstructive hypertrophic cardiomyopathy (HCM). The medicine may improve how your heart works and how well you can exercise.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06783166RecruitingPhase 2/Phase 3
Comparing two medications for acute heart failure with fluid buildup
This trial tests if dapagliflozin or acetazolamide works better for people hospitalized with heart failure who have extra fluid in their body (congestion). The study will compare how well each medication helps remove fluid when used with standard IV diuretics.
Al MansurahAges 18 years+ - NCT06428097RecruitingPhase 1
Thyroid hormone before heart transplant
This study tests whether giving a thyroid hormone supplement called levothyroxine before a heart transplant can help with recovery. It is for people already listed for a heart transplant who do not have thyroid problems.
San Francisco, CaliforniaAges 18 years+ - NCT06474832Recruiting
High-Intensity Interval Training for Chronic Stroke
This trial tests whether high-intensity interval training (short bursts of intense exercise mixed with rest) can help people who had a stroke more than 6 months ago improve their walking and overall fitness. It may be a good fit if you can already walk a bit and do not have unstable heart or lung problems.
TaipeiAges 18–69 - NCT06425614Recruiting
Blood Cell Recycling During Heart Surgery Trial
This trial tests whether giving back a patient's own platelets and red blood cells during heart surgery can reduce bleeding and the need for donor blood transfusions. It is for people having certain types of high-risk heart surgery with a heart-lung machine.
Bordeaux, FranceAges 18 years+ - NCT06425822Recruiting
Studying the left atrium in ventricular arrhythmia patients
This trial studies the upper left chamber of the heart (the left atrium) in people who have fast or irregular heartbeats from the lower chambers (ventricular arrhythmias). The goal is to see if there are specific patterns in the left atrium that might be linked to these arrhythmias, which could help tailor treatments in the future.
Jette, Brussels CapitalAges 18 years+ - NCT06467968Recruiting
Heart analysis during DOTATOC PET/CT for neuroendocrine tumors
This study looks at how a PET/CT scan (called gallium-68 DOTATOC) can also check your heart health while scanning for a neuroendocrine tumor. It aims to see if the routine scan can give extra information about your heart function without any extra visits or radiation.
Vandœuvre-lès-NancyAges 18 years+ - NCT06469450RecruitingPhase 1
How statins affect cells in healthy adults
This trial looks at how statins (cholesterol-lowering drugs) affect certain cells in healthy young adults. By participating, you help researchers understand how statins work in the body.
HelsinkiAges 18–40 - NCT06178744Recruiting
AI in heart transplant ultrasound study
This study uses artificial intelligence to look at echocardiograms (ultrasounds of the heart) from heart transplant patients. It aims to see if AI can help predict rejection or other problems, potentially reducing the need for biopsies.
Rochester, MinnesotaAges 18 years+ - NCT06192082Recruiting
Heart risks during painless stomach scope in frail elderly
This study looks at whether older, frail patients have heart problems during a painless stomach scope (gastroscopy). It aims to find safer ways to give sedation for these patients.
Beijing, Beijing MunicipalityAges 65–100 - NCT06285968Recruiting
Sleep health study for better heart health
This study tests whether improving sleep can help lower blood pressure and improve heart health. It is for adults with slightly elevated blood pressure and poor sleep who have not had heart disease or cancer.
New York, New YorkAges 30 years+ - NCT06306573Enrolling by invitation
CardioMEMS heart pressure monitor study in Medicare patients
This study looks at how well the CardioMEMS heart pressure monitor works for people with heart failure who are on Medicare. It gathers real-world information to see if the sensor helps improve health outcomes.
Atlanta, GeorgiaAges 18 years+ - NCT06224660RecruitingPhase 1
Gene therapy for heart problems in Duchenne muscular dystrophy
This trial tests an experimental therapy for heart weakness caused by Duchenne muscular dystrophy. It aims to improve how heart cells handle calcium to protect heart function.
Kansas City, KansasAges 18 years+ - NCT06286891Recruiting
Frailty and lung function after pulmonary endarterectomy
This study looks at how frailty, physical ability, and lung function change in people who have had surgery to remove blood clots from the lungs (pulmonary endarterectomy). It aims to help doctors better understand recovery after this procedure.
São Paulo, São PauloAges 18 years+ - NCT06226844Recruiting
Can a vibration device help people with leg artery disease walk further?
This study tests a device called BeatMove to see if it can improve walking distance for people with blocked leg arteries that cause pain when walking. It may help if you have this condition and already take medicines for it.
NîmesAges 18 years+ - NCT06320652Recruiting
Telemedicine for heart rehab
This trial tests if using video calls and an app for cardiac rehabilitation works as well as in-person visits. It may help you recover from heart conditions more conveniently.
HvidovreAges 18 years+ - NCT06276010Recruiting
Nafamostat mesilate for blood thinning in ECMO patients
This trial tests a medicine called nafamostat mesilate to prevent blood clots in patients who need ECMO (a machine that helps your heart and lungs) after heart surgery. It may offer a safer way to thin the blood compared to standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06303414Recruiting
Opening blocked carotid artery for ongoing symptoms
This trial tests a procedure to open a blocked carotid artery in the neck to improve blood flow to the brain. It's for people who still have symptoms (like weakness or vision problems) despite medical treatment.
Beijing, Beijing MunicipalityAges 18–80 - NCT06312748RecruitingPhase 1
Improving blood vessels in veterans with heart failure
This test is looking at whether certain medications (like statins) can help improve blood vessel health in veterans who have heart failure with preserved pumping function. It may help reduce symptoms and keep you out of the hospital.
Salt Lake City, UtahAges 18 years+ - NCT06286098Enrolling by invitationPhase 3
Alpha lipoic acid for kids on dialysis
This trial tests if alpha lipoic acid, a common supplement, can help reduce stress on the body for children who are on regular hemodialysis. It may offer a way to support their health during treatment.
Cairo, El WeiliAges 8–16 - NCT06262295Recruiting
Monitoring the safety of AVEIR leadless pacemakers
This study tracks the safety and performance of AVEIR VR LP and AVEIR AR LP leadless pacemakers in people who already have them or will get one. It helps doctors and researchers see how well these small heart devices work over time.
La TroncheAges 18 years+ - NCT06246760Recruiting
Exercise and fitness in healthy adults
This study looks at how breathing, body composition, and heart-lung fitness vary between people who exercise regularly and those who don't. You may qualify if you are generally healthy and can do a treadmill or bike test until you are too tired to continue.
Madrid, Comunity of MadridAges Any age - NCT06205576Recruiting
Balloon treatment for narrowed AV fistula veins
This trial tests a balloon device to open up narrowed veins in an AV fistula used for dialysis. It may help if your fistula has a blockage that causes problems like high pressure or low blood flow.
BeijingAges 18–85
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.