Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT07140731Recruiting
Symani Restore study for moyamoya disease surgery
This study tests if the Symani surgical system helps surgeons perform a delicate brain blood-vessel bypass in people with moyamoya disease. It may offer a precise, minimally invasive option for those needing neurosurgery.
Buffalo, New YorkAges 18 years+ - NCT07140952Recruiting
Heart-healthy diet and exercise for stroke survivors
This study tests a heart-healthy diet and exercise plan for stroke survivors to improve health and fitness. It is done virtually to make it easy to join from home.
Florence, South CarolinaAges 45–80 - NCT07141303RecruitingPhase 3
Steroid after stroke clot removal for anterior circulation large vessel occlusion
This trial tests if giving a steroid (methylprednisolone) directly into the brain artery after successful clot removal improves recovery. It is for people who had a large stroke in the front part of the brain and got the clot out within 24 hours.
Xi'an, ShaanxiAges 18–80 - NCT07141251RecruitingPhase 1
New technique for complex aortic aneurysm repair
This trial tests a new technique (BAO-G) for repairing complex aortic aneurysms using standard devices. It aims to make surgery safer for patients with aneurysms in the chest and belly area.
Beijing, Beijing MunicipalityAges 18–80 - NCT07141745Recruiting
Comparing energy types for repeat atrial fibrillation treatment
This trial compares two different energy methods (electroporation vs radiofrequency ablation) guided by 3D imaging for people who have had a prior ablation for atrial fibrillation but still have recurrences. It aims to find which method is safer and more effective for repeat procedures.
WroclawAges 18–85 - NCT07143136RecruitingEarly Phase 1
Colchicine for heart attack patients with stents
This trial tests if giving colchicine early after a heart attack (when a drug-coated stent is placed) can help reduce complications. It looks at short-term benefits for people with Non-STEMI.
Asyut, Asyut GovernorateAges 18 years+ - NCT07143149Recruiting
Smart tool for cholesterol after stroke or mini-stroke
This trial tests a smart computer tool that helps doctors manage your cholesterol treatment with Evolocumab (Repatha). If you have had a recent stroke or mini-stroke and are already taking this medicine, the tool may help you reach your LDL (bad cholesterol) goal faster.
BeijingAges 18 years+ - NCT07143175Recruiting
Foot Care Navigator Pilot for Diabetes Patients
This trial tests a patient navigator program to help people with diabetes who have had two or more toes amputated due to a foot ulcer. It aims to support recovery and follow-up care.
Atlanta, GeorgiaAges 18 years+ - NCT07143201RecruitingPhase 2
Precision dosing of ibuprofen for PDA in premature babies
This study tests a personalized way to give ibuprofen to very premature babies with a heart condition called PDA. It aims to see if adjusting the dose can help close the heart opening more safely.
Hamilton, OntarioAges Up to 6 months - NCT07143357Recruiting
Mind-body recovery program for cardiac arrest survivors and their caregivers
This trial tests a mind-body program to help cardiac arrest survivors and their caregivers recover together after a cardiac arrest. It combines in-person and video sessions to reduce emotional distress and improve wellbeing.
Boston, MassachusettsAges 18 years+ - NCT07143539Recruiting
Early exercise rehab after hospital stay for pulmonary embolism
This study tests if starting a supervised exercise program early after a hospital stay for a blood clot in the lungs (pulmonary embolism) helps patients recover better and feel less breathless. It is for people at higher risk of ongoing symptoms after their clot.
AarauAges 18 years+ - NCT07143799Recruiting
Scalp block vs general anesthesia for subdural hematoma drainage
This study compares two ways to manage pain during surgery to drain a subdural hematoma (a collection of blood pressing on the brain). Some patients will get a scalp block (numbing injections in the head) while others will receive general anesthesia (being put to sleep). The goal is to see which approach works better and has fewer side effects.
SohagAges 18–75 - NCT07144189Recruiting
AI helps diagnose low-gradient aortic stenosis
This trial is testing whether an artificial intelligence (AI) program can better identify low-gradient aortic stenosis, a type of heart valve narrowing, by looking at your echocardiogram (heart ultrasound). It aims to help doctors diagnose this condition more accurately without any extra procedures.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07144423Recruiting
Comparing two drainage methods for chronic subdural hematoma
This trial compares two surgical techniques—using a small endoscope (camera) versus a single burr hole—to drain blood from a chronic subdural hematoma (a slow bleed on the brain surface). The goal is to see which method leads to better recovery and fewer complications.
Beijing, Beijing MunicipalityAges 18–90 - NCT07144436Recruiting
Pain after stroke: brain scan and treatment study
This trial tests whether a special kind of brain scan (called tAN-fMRI) can help understand and treat pain that happens after a stroke. You may qualify if you had a stroke at least 6 months ago and are between 18 and 80 years old.
Charleston, South CarolinaAges 18–80 - NCT07144930Recruiting
Cognitive-motor training for stroke and Moyamoya disease
This trial tests a combined thinking and movement training program for people who have had a stroke or have Moyamoya disease and still have some thinking or movement problems. It may help improve both mental and physical abilities.
TaipeiAges 20–100 - NCT07145138Recruiting
Multi-ethnic dilated cardiomyopathy registry
This study is a registry for people with dilated cardiomyopathy (DCM)—a condition where the heart's main pumping chamber becomes enlarged and weak. It aims to learn more about DCM, especially in people from different ethnic backgrounds, by collecting health information over time.
Chicago, IllinoisAges 18 years+ - NCT07145463Recruiting
New delivery system for severe aortic stenosis treatment
This trial tests a new delivery system (VitaFlow Liberty Flex) for placing a replacement aortic valve in people with severe aortic stenosis. It is designed for patients whose heart anatomy (a steep angle between the heart and aorta) makes the procedure more challenging.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07146048RecruitingPhase 3
Stopping penicillin for early rheumatic heart disease
This trial tests whether it is safe to stop taking daily penicillin for children and teens whose rheumatic heart disease has improved or stayed mild. If you took part in the GOALIE study and your heart condition is now stable, this study may help determine if you can safely stop medication.
Kampala, UGAges 5–20 - NCT07146789Recruiting
Home arm exercise program for stroke recovery
This trial tests a home-based arm exercise program for people who had a single stroke 3 to 12 months ago. The program is designed to help improve arm function and quality of life through repeated, graded movements.
ValenciaAges 18 years+ - NCT07147569Recruiting
Gore AC device safety study for aortic aneurysm
This study looks at how well the Gore AC device works for people with certain types of aortic aneurysms in Japan. It follows patients after their procedure to check safety and device performance.
MinatokuAges Any age - NCT07147660Recruiting
Vision training to help you drive after a stroke
This study tests a vision training program to help people who lost part of their eyesight after a stroke. The goal is to see if it can improve your ability to drive safely.
KongsbergAges 20–85 - NCT07148089RecruitingPhase 1
Gene therapy study for CPVT heart condition
This trial tests a new gene therapy called SGT-501 for people with a genetic heart condition called CPVT, which can cause dangerous fast heartbeats. The goal is to see if the treatment can reduce these episodes.
Boston, MassachusettsAges 7 years+ - NCT07149038Recruiting
Ear stimulation device study for vascular dementia
This trial tests a device that stimulates a nerve in your ear to help with memory and thinking problems caused by small blood vessel damage in the brain. It's for people with vascular dementia or a milder form called vascular mild cognitive impairment.
Hwaseong-si, Gyeonggi-doAges 55–89
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.