Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT06285084Recruiting
Deep learning ECG test for sports eligibility
This trial uses a deep learning computer program to analyze your heart's electrical activity (ECG) during a routine check-up. It aims to help doctors decide if it's safe for you to play competitive sports.
Milan, LombardyAges 18–60 - NCT06198816Recruiting
Ultrasound and balloon treatment for old leg clots
This study tests a new way to treat long-standing blood clots in the leg using ultrasound waves and a balloon procedure. It aims to improve blood flow and reduce symptoms like swelling and pain for people who haven't gotten better with standard treatments.
Milan, ItalyAges 18–75 - NCT06062017Recruiting
Potassium, hydration, and heart health in young adults
This study looks at how potassium and hydration affect heart and kidney health in healthy young adults. It may help you understand your own health and contribute to new knowledge about preventing disease.
Auburn, AlabamaAges 18–30 - NCT06075420Recruiting
Shorter blood thinner use after GENOSS stent in heart disease
This trial tests whether a shorter course of dual antiplatelet therapy (two blood thinners) is safe and effective for people who have received a GENOSS stent for coronary artery disease. It aims to reduce the risk of bleeding while still preventing heart attacks.
Wŏnju, Gangwon StateAges 19 years+ - NCT06019364Enrolling by invitation
Whole Blood Transfusion for Acute Bleeding
This trial looks at people who received whole blood transfusions during a sudden, heavy bleeding episode. It aims to learn more about how well whole blood works in these situations.
ÖrebroAges 18 years+ - NCT06024759Recruiting
Predicting risk in left ventricular non-compaction
This study is for adults who have been diagnosed with a condition called left ventricular non-compaction (LVNC). It aims to find out what might predict future health problems in people with this condition. By joining, you can help researchers learn more about LVNC and improve care for others like you.
London, OntarioAges 18 years+ - NCT05959252RecruitingPhase 2
Bivalirudin vs heparin for blood thinning during ECMO
This Phase 2 trial compares two blood-thinning medicines—bivalirudin and heparin—in people on ECMO (a machine that supports breathing and/or circulation). It aims to see which medicine works better and is safer while you are connected to the ECMO circuit.
Sydney, New South WalesAges 18 years+ - NCT06061978Recruiting
Pacing after a heart procedure for rapid atrial fibrillation
This trial studies whether a special type of pacing (stimulating the heart's natural electrical system) works better than standard pacing after a procedure to control very fast heart rhythms. It's for people who already have a pacemaker and are getting a specific treatment for atrial fibrillation.
CaenAges 18 years+ - NCT06128980RecruitingPhase 2/Phase 3
Stopping heart meds after recovery from fast heartbeat damage
This trial tests if patients whose heart function returned to normal after treating a fast heartbeat can safely stop their heart failure medications. It aims to see if treatment can be withdrawn without the heart problems coming back.
CopenhagenAges 18 years+ - NCT06081881Recruiting
High blood pressure in lungs after a severe blood clot
This study monitors people who had a severe lung blood clot to see if they develop high blood pressure in the lungs over time. It aims to catch the condition early, so treatment can start sooner.
AsyutAges 18–80 - NCT06016608Recruiting
Polyvascular disease imaging study
This study uses a special camera to take detailed pictures of artery blockages in people with heart disease, stroke, or mini-stroke. It may help doctors better understand how to treat multiple blocked arteries.
Harbin, HeilongjiangAges 18 years+ - NCT06015191Recruiting
Remote heart rehab for teens with congenital heart disease
This trial tests a home-based cardiac rehab program for adolescents with certain types of congenital heart disease. It aims to help you exercise safely and improve your fitness using online coaching and monitoring.
Kansas City, MissouriAges 12–19 - NCT06055504Recruiting
Personalized defibrillator plan for non-ischemic heart failure (SPANISH-1)
This trial is testing a personalized approach to deciding who gets an implantable defibrillator (ICD) for people with heart failure due to dilated cardiomyopathy (not from blocked arteries). It aims to see if MRI scans and other factors can better match the device to those who need it most.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT05951764Recruiting
Checking risk prediction for heart and brain conditions
This study builds or tests computer models that predict risk for heart (cardiovascular) and thinking/memory (neurocognitive) problems using information from people in the general population. It may help improve early detection and planning for care.
ParisAges 45 years+ - NCT06026436Recruiting
Predicting clot and bleeding risk in kidney disease patients after a heart attack
This trial tests whether a blood test looking at platelets and tiny cell particles can help predict future blood clots or bleeding in people who have both chronic kidney disease and a recent heart attack. The goal is to improve treatment safety.
MarseilleAges 18–90 - NCT06091904Recruiting
Sufentanil for brain bypass surgery patients
This trial tests the pain medicine sufentanil to see how it affects blood pressure and heart rate during brain bypass surgery. It may help doctors better manage anesthesia for people having this type of surgery.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06087029Recruiting
Improving outcomes in aortic dissection
This study tests a minimally invasive procedure called TEVAR to repair a type B aortic dissection (a tear in the wall of the main artery from your heart). It may help prevent further damage and improve recovery.
Birmingham, AlabamaAges 21 years+ - NCT06004544Recruiting
Heart screening in pregnant women without symptoms
This study uses echocardiography (an ultrasound of the heart) to check for hidden heart problems in pregnant women who do not have any symptoms. It aims to find issues early and improve care.
Karachi, SindhAges Any age - NCT05838287RecruitingPhase 4
Pioglitazone for heart failure with preserved pumping in type 2 diabetes
This trial tests whether pioglitazone (a diabetes medicine) helps people who have type 2 diabetes and a specific type of heart failure where the heart pumps normally. It may improve heart failure symptoms and function in carefully selected patients.
San Antonio, TexasAges 30–70 - NCT05915299Recruiting
Heart surgery donor heart monitoring registry
This is a registry that collects information about how donated hearts are handled using a portable machine that keeps the heart healthy outside the body. It may help researchers improve future care, but it usually does not test a new medication.
Phoenix, ArizonaAges Any age - NCT05834777RecruitingPhase 3
Prevent low blood pressure during dialysis by blocking bradykinin
This Phase 3 trial tests a medicine that blocks a body signal (bradykinin) to help prevent dangerous drops in blood pressure during hemodialysis. If you often get “intradialytic hypotension,” this study may help you dialyze more safely.
Nashville, TennesseeAges 18–80 - NCT05778500Recruiting
Using ultrasound heart scan reports to improve report accuracy
This study tests computer-guided “algorithms” that may make echocardiogram (heart ultrasound) reports more accurate. If you agreed to let the study use your relevant clinical information, your scan data may be used to improve reporting.
MilanAges 18 years+ - NCT05868525RecruitingPhase 4
Compare two aspirin doses after blunt vessel injury
This trial tests whether taking a lower-dose aspirin (81 mg) works as well as a higher-dose aspirin (325 mg) to prevent stroke after a blunt injury that affects blood vessels in the neck/head. It may help some patients lower their stroke risk with the simplest, safest dose.
Loma Linda, CaliforniaAges 18 years+ - NCT05831709Recruiting
Hormone therapy and supervised exercise in menopausal women
This study looks at how hormone replacement therapy and a supervised exercise program may change body composition, heart health risk, and insulin sensitivity in postmenopausal women. It may help participants understand which combination works best for metabolic and cardiovascular health after menopause.
GhentAges 45–65
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.