Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT06341231Recruiting
Personalized blood thinners for lung clots
This study tests personalized blood thinner treatments for people with blood clots in their lungs. It looks for patients who are older, have kidney problems, or have cancer, to see if adjusting the treatment helps them more.
Changsha, HunanAges 18 years+ - NCT05114850Recruiting
Follow-up study for people treated with TricValve
This study looks back at patients who were successfully treated with TricValve bicaval valve devices and then follows up with their outcomes. You might join if you (or your legal guardian) agree to be included.
Sankt Pölten, Lower AustriaAges 18 years+ - NCT05638503Recruiting
Study of heart changes in people with hypertension
This study looks at new ways to measure heart structure and heart pumping function in people with high blood pressure. The results may help doctors better understand heart changes over time and improve care.
Jinan, ShandongAges 30–75 - NCT04839887Recruiting
Quality of life after stroke in adults aged 18–65
This trial looks at what affects quality of life after an ischemic stroke (a type of stroke caused by a blocked blood vessel) in younger adults. You may be able to join if you can complete questionnaires about your recovery and daily life.
OlomoucAges 18–65 - NCT04619355Recruiting
People who had a special heart scan during stent placement
This study follows people who already had a stent put in (PCI) using a special imaging test (NIRS-IVUS) to look at heart outcomes over time. If you agreed and can attend follow-up visits, this registry may help doctors better understand how this imaging-guided approach performs.
SeoulAges 19 years+ - NCT05759676Recruiting
Diabetes and a new drug-free heart stent after angioplasty
This trial tests whether a polymer-free amphilimus-eluting stent is safe and works well for people with diabetes after a recent heart blockage procedure. It may help improve how well the artery stays open, while tracking side effects over time.
SeoulAges 19 years+ - NCT06067789Recruiting
Testing spinal vs. general anesthesia for leg blood flow surgery
This study tests a new way to give anesthesia during leg surgery to improve blood flow. It aims to see if spinal anesthesia works better than general anesthesia for recovery and comfort.
Ottawa, OntarioAges 18 years+ - NCT05761314Recruiting
Study treatments for cancers in people with RASopathy
This study looks at people who have a RASopathy—a genetic condition—and also have solid tumors (tumor growths not in blood). To join, your RASopathy must be confirmed by genetic testing, not only by symptoms.
RomaAges Any age - NCT06323018Recruiting
Remote preconditioning for cemented hip replacement recovery
This trial tests whether a simple, safe treatment called remote ischemic preconditioning (using a blood pressure cuff on your arm just before surgery) can help people recover better after cemented hip replacement. It is for patients aged 66 and older who are scheduled for this surgery.
Tartu, TartuAges 65–90 - NCT04912323Recruiting
Drug dissolving stent for blocked below-knee arteries
This trial studies a drug-eluting dissolving scaffold placed in blocked arteries below the knee to improve blood flow. It may help people whose leg circulation problems are severe enough to limit walking or threaten the limb, but only if their blockages fit specific imaging and procedure requirements.
GrazAges 18–90 - NCT04158479Recruiting
Registry for people on ECMO life support
This registry collects information about people who are placed on ECMO, a heart-lung machine used to support breathing and/or circulation. It may help doctors better understand who benefits and how to manage ECMO in the future.
Beijing, Beijing MunicipalityAges Any age - NCT05856318Recruiting
Study heart and diabetes health in first-time pregnancy
This study looks at how your heart health and blood-sugar health change when you are trying for, or not planning, a first pregnancy. It may help researchers understand which early health factors matter for you and future pregnancy outcomes.
CambridgeAges 18–45 - NCT06075940Recruiting
A dissolving stent for blocked leg arteries below the knee
This study tests a new bioresorbable scaffold (like a temporary mesh) that slowly dissolves, releasing medication to keep your below-the-knee artery open. It is for people with severely blocked leg arteries causing pain or wounds at rest (Rutherford 4 or 5).
Randwick, New South WalesAges 18 years+ - NCT06356727Recruiting
Blood vessel health test for heart recovery
This study checks if tiny blood vessel problems in the heart affect how well the heart muscle recovers after being weak. It uses special imaging during a routine heart catheterization to look at these small vessels.
FerraraAges 18–85 - NCT06356207Recruiting
Measuring heart pause time in fainting during tilt table test
This study tests a new way to measure how long it takes for your heart to pause during a tilt table test, in people with reflex fainting spells. The results may help doctors decide if a pacemaker is right for you.
BolzanoAges 18 years+ - NCT06360627Recruiting
Low-dose CT with contrast for lung checks
This study tests a special low-radiation CT scan with a contrast dye called Iomeron 400 to see if it works well for checking lung nodules or pneumonia.
ZurichAges 18 years+ - NCT05309460RecruitingPhase 4
Labetalol or nifedipine to treat postpartum high blood pressure
This study compares two common blood pressure medicines—labetalol and nifedipine—to control high blood pressure after childbirth. It may help you and your care team find the safest way to bring your blood pressure back to normal after delivery.
Omaha, NebraskaAges 19 years+ - NCT06362343Recruiting
Personalized dosing study for Xa inhibitor blood thinners
This study looks at how the body processes a certain type of blood thinner (Xa factor inhibitors) to help doctors find the right dose for each person. If you have a blood clot in your lungs and are on long-term treatment, this trial might help improve your care.
Beijing, Beijing MunicipalityAges 18–120 - NCT02621216Recruiting
Emotional stress check during heart stent procedure
This study looks at how emotional stress affects people during and around a heart stent procedure. It may help improve support for patients who feel anxious or stressed during coronary interventions.
Tilburg, North BrabantAges 18 years+ - NCT06363604Recruiting
Alcohol injection with ablation for persistent atrial fibrillation
This trial is testing a new approach to treat persistent atrial fibrillation (a type of irregular heartbeat) by combining standard catheter ablation with a special injection of alcohol (ethanol) into certain heart veins. It may help people whose symptoms haven't improved with medication.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT05976152RecruitingPhase 3
Butyphthalide to improve thinking after a recent stroke
This Phase 3 study tests whether butyphthalide can help thinking and memory improve after an acute ischemic stroke. It compares people who take the study medicine versus usual care, and measures cognitive (thinking) changes over follow-up.
Dandong, LiaoningAges 60 years+ - NCT03847025Recruiting
Lead extraction registry for pacemaker and defibrillator patients
This registry collects information from people who are having pacemaker or defibrillator leads removed. It helps doctors and researchers understand how these procedures are done and what happens afterward.
Portland, OregonAges Any age - NCT06361784Recruiting
Heart-Sparing Radiation for Stage 3 Lung Cancer
This study tests a new way of planning radiation therapy for stage 3 lung cancer. By carefully mapping the heart's structure, doctors aim to protect it from radiation and improve treatment safety.
MilanAges Any age - NCT06365138Recruiting
Activity at the time of aortic rupture in aneurysm patients
This study looks at what patients were doing just before their aortic aneurysm ruptured, to help understand possible triggers. It is a simple observational study that asks about your activity at the time of rupture.
AugsburgAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.