Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT05829317RecruitingPhase 4
Magnesium to prevent new atrial fibrillation in ICU patients
This trial tests whether giving magnesium can lower the chance of developing new irregular heartbeat (atrial fibrillation) in critically ill adults in the ICU. If you are at risk but do not already have this rhythm issue, magnesium may help prevent it.
Hamilton, OntarioAges 18 years+ - NCT05649826Recruiting
Ultrasound guidance tool for clearer heart ultrasound images
This trial tests an automated computer tool that helps guide an ultrasound exam of the heart, aiming to get better, usable images. You may benefit if your heart ultrasound is usually hard to capture or takes extra effort to obtain clear pictures.
Detroit, MichiganAges 18–120 - NCT05790603Recruiting
Patent hemostatic device after wrist procedures with pressure
This trial tests whether a specific wrist compression device with measured pressure works better for stopping bleeding after a heart catheter procedure done through the radial artery (wrist). It may help reduce complications like prolonged bleeding once the procedure is finished.
Beijing, Beijing MunicipalityAges 18–80 - NCT05824364Recruiting
Exercise program after heart transplant
This trial studies an exercise program for people who have recently had a heart transplant. It may help improve recovery and physical function after transplant.
Milan, MilanAges 18 years+ - NCT05814146Recruiting
Testing a dialysis fluid change for kidney failure
This trial studies whether using a dialysis fluid with a different bicarbonate level can help people with long-term kidney failure treated with regular hemodialysis. If you qualify, you may be assigned to receive a specific bicarbonate concentration during your dialysis sessions.
Boston, MassachusettsAges 18–120 - NCT05782270RecruitingPhase 4
Blood thinner medicines after bypass surgery with artery unblocking
This trial studies which blood-thinning medicine combination is safest and most helpful after coronary bypass surgery combined with a procedure to unblock the artery (endarterectomy). It focuses on preventing dangerous blood clots while also avoiding excess bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05782777Recruiting
Cholesterol medicines after stent: combo pill vs single pill
This trial compares two cholesterol-lowering treatment plans after a heart procedure where new drug-eluting stents were placed: a combination of high-intensity statin plus ezetimibe versus high-intensity statin alone. It may help find which option lowers cholesterol more effectively and safely over the first year after the procedure.
SeoulAges 19 years+ - NCT05902923Recruiting
Testing balloon and stent devices for blocked kidney or leg arteries
This trial studies how safe and well several balloon and stent devices work for treating narrowed or blocked arteries in the kidney area or the groin/upper leg. It may help patients who fit the specific artery location and device-use instructions for these treatments.
AvignonAges 18 years+ - NCT05640453RecruitingPhase 4
Testing pregabalin or dexmedetomidine for post-surgery delirium
This study compares two medicines—pregabalin and dexmedetomidine—to treat confusion (called delirium) after heart bypass surgery. It aims to see which drug works better to reduce delirium symptoms in older adults after coronary artery bypass surgery.
Tanta, El-Gharbia GovernorateAges 65 years+ - NCT05888974Recruiting
Test of heart ultrasound to guide fluids in shock
This study checks whether a specific heart ultrasound measurement can help doctors decide if you will benefit from extra fluid during early emergency treatment for shock. It may help avoid unnecessary fluids and support faster, safer decision-making.
NîmesAges 18 years+ - NCT05732779Recruiting
App-based check-ins to help teens take transplant medicines
This study tests a phone app that uses video check-ins (called directly observed therapy) to help adolescent heart-transplant patients take their immunosuppression medicines as prescribed. It may help reduce missed doses, which is important for protecting the transplanted heart.
Coral Gables, FloridaAges 10–21 - NCT05747196Recruiting
Testing a new heart-failure fluid-removal device in hospitals
This trial tests whether the eLym™ device is safe and practical to use in people hospitalized for worsening heart failure with excess fluid. It may help reduce fluid overload while the team checks safety during and after the procedure.
Tbilisi, GeorgiaAges 18 years+ - NCT05825937Recruiting
Noninvasive blood pressure monitoring during planned procedures
This study tests a noninvasive way to measure blood pressure during planned (elective) heart or brain blood vessel procedures. If you are having one of these elective surgeries and fit the timing needs, you may help compare monitoring methods for safety and accuracy.
Saskatoon, SaskatchewanAges 18 years+ - NCT05674630RecruitingPhase 4
Drug-coated balloon for coronary artery blockages
This trial studies whether a drug-coated balloon can treat certain coronary artery narrowings in adults with chronic (long-term) coronary disease. It may help prevent re-narrowing after the procedure for people whose tests show the blockage is significant and needs treatment.
LuganoAges 18 years+ - NCT05843500Recruiting
CTEPD and CTEPH registry for long-term blood-clot lung disease
This study builds a registry to learn about people with chronic blood-clot lung disease (CTEPD/CTEPH) and what symptoms and test results look like over time. It may help clinicians better understand the condition and improve future care, since your participation supports data collection rather than a new drug.
San Francisco, CaliforniaAges 18 years+ - NCT05733585Recruiting
Testing a clot-stopping product in open abdominal aorta surgery
This study looks at how well a hemostatic (bleeding-stopping) product called PuraBond works during open surgery for an abdominal aortic aneurysm or severe narrowing/blockage of the aorta/iliac arteries. It’s intended for people whose surgeon thinks standard methods may not fully stop bleeding.
Milan, ItalyAges 18 years+ - NCT05764772Recruiting
Testing features of plaque in symptomatic carotid narrowing
This study looks at the makeup of plaque in the carotid artery (the neck blood vessel to the brain) in people who recently had a stroke caused by that narrowing. Researchers will use MRI and planned surgery to see which plaque components may matter for stroke risk and outcomes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05826587Recruiting
Mobile coaching to prevent falls during heart rehab
This study adds a personalized home exercise program delivered by a smartphone app to standard outpatient heart rehabilitation. It aims to improve balance and strength to lower the chance of falling during the rehab period.
Scottsdale, ArizonaAges 18 years+ - NCT05904548Recruiting
Atrial flutter ablation with an MRI-guided mapping system
This trial studies how well an MRI-guided approach works during atrial flutter ablation. If you’ve had recent atrial flutter episodes, it may help doctors target the heart rhythm problem more precisely and safely.
Baltimore, MarylandAges 18 years+ - NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT05436600Recruiting
Exercise program for people with narrowed neck arteries
This trial studies whether a supervised exercise program can improve mobility and balance in people who have narrowed carotid arteries in the neck but no stroke symptoms. If you fit the criteria, the goal is to see whether exercise helps your movement and safety without increasing risks.
Baltimore, MarylandAges 18–89 - NCT05280028Recruiting
Hormone treatment for overactive bladder and mood symptoms
This trial studies whether hormone treatment can improve overactive bladder symptoms, sexual well-being, mood (depressive symptoms), and body “autonomic” function (automatic body functions like heart rate and sweating) in post-menopausal women. It may help by targeting menopausal changes that can affect these symptoms.
Banqiao District, New TaipeiAges 20 years+ - NCT05612906Recruiting
Nerve ablation study for difficult high blood pressure
This trial studies a procedure called renal nerve denervation (ablation) to improve kidney-related blood pressure in people whose blood pressure stays high despite medications. It may help some people lower blood pressure and improve blood pressure control over time.
Xiamen, FujianAges 18–75 - NCT05292404RecruitingPhase 4
PCSK9 medicine soon after heart attack to protect the heart
This trial studies whether starting a PCSK9-blocking medicine early after a specific type of heart attack can improve heart outcomes. You may be eligible if you have a STEMI heart attack soon, are planning a procedure to open the blocked artery, and meet safety and pregnancy criteria.
Shanghai, Shanghai MunicipalityAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Mental health
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- Immune system & allergy
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.