Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT07226609Recruiting
Plant-based diet study for multiple myeloma patients
This study tests if a plant-based diet can help people with newly diagnosed multiple myeloma who are receiving a standard 4-cycle drug combination (DRVd). Researchers want to see if changing what you eat might improve treatment results.
Basking Ridge, New JerseyAges 18 years+ - NCT07226934Recruiting
AI-generated question list for blood cancer patients
This trial tests if an AI tool can help you create a personalized list of questions about your cancer treatment to ask your doctor at your next visit. It is for patients with lymphoma or multiple myeloma who get regular infusion therapy.
St Louis, MissouriAges 18–99 - NCT07227246RecruitingPhase 3
Testing rFVIIa for bleeding stroke within 2 hours
This trial tests whether a drug called Recombinant Factor VIIa (rFVIIa) can safely help stop bleeding in the brain during a hemorrhagic stroke. The goal is to give the drug as quickly as possible, within 2 hours of stroke onset, to see if it improves outcomes.
Birmingham, AlabamaAges 18–80 - NCT07227740Recruiting
Testosterone treatment for blood vessel health after spinal cord injury
This study looks at whether low testosterone affects blood vessel health in men with recent spinal cord injury. It tests if testosterone replacement can help improve blood vessel function.
Englewood, ColoradoAges 18–89 - NCT07229196Recruiting
Comparing two exercise programs for lowering blood pressure
This study compares two types of exercise programs (short bursts of high-intensity exercise vs. moderate continuous exercise) to see which one lowers blood pressure better in people with hypertension. You may qualify if you have high blood pressure and are between 30 and 59 years old.
La Plata, Buenos AiresAges 30–59 - NCT07229248RecruitingPhase 3
Balloon vs. Stent in Young Heart Attack Patients
This trial compares a drug-coated balloon (DCB) to a drug-eluting stent (DES) in younger adults having their first major heart attack. The goal is to see which treatment works better when the artery is opened quickly.
KarachiAges 18–49 - NCT07230067Recruiting
Sepsis with low platelets: platelet transfusion study
This study looks at whether platelet transfusions help patients with sepsis and very low platelet counts recover better. If you or your loved one had sepsis, a low platelet count, and were in the ICU for at least two days, this trial may be relevant.
Guangzhou, GuangdongAges 18 years+ - NCT07230470Recruiting
Walking rehabilitation after stroke: Exoskeleton vs treadmill
This study compares two robotic devices (the LoKomat exoskeleton and the C-Mill treadmill) to see which one helps people walk better after a stroke. If you are recovering from a stroke and able to understand instructions, you may be able to join.
SalamancaAges 18–65 - NCT07230847Recruiting
Healing of drug-coated vs. standard stents in high-bleeding-risk patients
This trial compares two types of stents (a drug-coated stent and a standard drug-eluting stent) in people with acute coronary syndrome who also have a high risk of bleeding. It uses a special camera to look at how the artery heals one month after the stent is placed.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07230964Recruiting
Heart valve study using a non-invasive skin test
This trial tests a special skin test (impedance cardiography) that may detect heart muscle changes in people with aortic stenosis. It could help doctors decide when valve replacement is needed.
Chicago, IllinoisAges 18 years+ - NCT07231172Recruiting
Fatigue after stroke and its link to clinical factors
This study examines how fatigue affects people who have had a stroke, looking at physical and mental health factors. It may help understand why some people feel more tired than others after a stroke.
AnkaraAges 18 years+ - NCT07231835Recruiting
Coronary outcomes with drug-coated balloon treatment
This study tracks patients who receive a special balloon coated with medicine (paclitaxel) to open blocked heart arteries. It aims to understand how well this treatment works for various types of blockages.
AmsterdamAges 18 years+ - NCT07231939Recruiting
Testing diabetes drugs to protect kidneys after heart procedures
This study is testing whether a class of diabetes medicines called SGLT2 inhibitors (specifically empagliflozin or dapagliflozin) can prevent kidney injury after heart procedures that use contrast dye.
BydgoszczAges 18 years+ - NCT07231952RecruitingPhase 2
Pirtobrutinib, venetoclax, and rituximab for Waldenstrom's macroglobulinemia
This trial tests a combination of three drugs (pirtobrutinib, venetoclax, and rituximab) for people newly diagnosed with Waldenstrom's macroglobulinemia who have not had treatment before and need therapy for their symptoms.
Boston, MassachusettsAges 18 years+ - NCT07232017Recruiting
Intensive blood pressure management study at Cleveland Clinic
This trial tests a program to help people with high blood pressure get it under better control. If you have high blood pressure that is not well-managed, this study may offer extra support and monitoring.
Cleveland, OhioAges 18–85 - NCT07232277Recruiting
Vein congestion and kidney injury after heart surgery
This trial looks at how fluid buildup in veins might relate to kidney injury after planned heart surgery. It aims to find ways to prevent kidney damage. Participants must be having planned (non-emergency) heart surgery, be 18 or older, and have healthy kidneys and overall health.
Yangzhou, JiangsuAges 18 years+ - NCT07232498Recruiting
Early ultrasound-guided movement after a stroke
This trial tests if starting supervised mobility early (within 48 hours) using Doppler ultrasound to guide care can help recovery in adults who just had a stroke caused by a clot. It may help you avoid complications and regain function sooner.
Coimbra, Coimbra DistrictAges 18 years+ - NCT07233161Recruiting
Modified arm therapy for early stroke recovery
This trial tests a modified version of constraint-induced movement therapy to help improve arm function in people who have had a stroke within the last 15 days. You may benefit if you have weakness in one arm and can follow simple instructions.
Barcelona, BarcelonaAges 18 years+ - NCT07233798Recruiting
Dural pulsation in lumbar spinal stenosis
This study looks at a natural movement called dural pulsation (pulsing of the spinal sac) in people with lumbar spinal stenosis. It might help doctors understand the condition better and could lead to better treatments for your back or leg pain.
Pendik, IstanbulAges 18–85 - NCT07233915Recruiting
Genetic Study of Berry-Shaped Brain Aneurysms
This study looks at the genetic makeup of people with berry-shaped brain aneurysms. It may help researchers understand why some aneurysms rupture and others don't.
Milan, MIAges 18–80 - NCT07234422RecruitingPhase 3
Selenium and CoQ10 for heart failure
This study tests whether adding selenium and CoQ10 (two natural supplements) to standard heart failure treatment helps people with chronic heart failure feel better and improve their health. Researchers are using a registry-based approach to track participants in the Netherlands.
AlkmaarAges 18 years+ - NCT07234565Recruiting
Improving social frailty through interactive learning
This trial tests a social program delivered over WeChat to help older adults with heart failure who feel socially frail. It aims to improve social connections and reduce frailty through interactive learning.
ShanghaiAges 60 years+ - NCT07234955Recruiting
Minimally invasive surgery for deep brain bleeding
This trial tests a minimally invasive surgery to remove blood clots deep in the brain after a spontaneous bleed. It may help patients with moderate to large bleeds who are at least 18 and up to 80 years old.
Ho Chi Minh City, Ho Chi MinhAges 18–80 - NCT07235358Recruiting
Pecan snacking for prediabetes health study
This study tests if eating pecans daily as a snack can improve heart health and blood sugar control in people with prediabetes. You would replace typical sugary or fatty snacks with pecans for several weeks, and researchers will track changes in your cholesterol and blood sugar.
University Park, PennsylvaniaAges 25–65
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.