Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT07241520RecruitingPhase 3
Testing SHPL-49 injection for recent stroke patients
This trial tests a new medication, SHPL-49, given as an injection to people who have just had a stroke caused by a blood clot (ischemic stroke). It is for patients who are already receiving standard clot-busting treatment within 8 hours of symptoms starting. The study will see if adding this drug helps improve recovery.
Linfen, ShanxiAges 18–80 - NCT07241572Recruiting
Heart injury risk during below-knee surgery
This trial checks for heart muscle injury during surgery on the lower leg (below the knee). It helps doctors understand how to better protect patients having this type of operation.
AnkaraAges 18 years+ - NCT07242768Recruiting
Long-term exercise follow-up for artery narrowing
This trial looks at the long-term effects of regular exercise for people with narrowed brain arteries. It follows participants from a previous study to see if exercise continues to help over three more years.
BeijingAges 40–80 - NCT07243080RecruitingPhase 4
Blood thinner comparison to prevent clots after belly surgery
This trial compares two blood thinners, Rivaroxaban (a pill) and Enoxaparin (a shot), to see which works better at preventing dangerous blood clots in the legs after emergency abdominal surgery. It may help you if you need to stay in bed for more than a day after your operation.
Lahore, Punjab ProvinceAges 18–80 - NCT07243769Recruiting
Comparing exercise types for heart rehab
This trial compares core, aerobic, and combined exercise in patients doing phase II cardiac rehab. It aims to find which type works best for heart recovery.
TaipeiAges 18 years+ - NCT07244484Recruiting
Brain Training for Heart Health in Coronary Artery Disease with Anxiety
This trial tests a brain training technique (neurofeedback) to help people with coronary artery disease and anxiety. It aims to improve heart rate control by targeting a specific brain area.
Shenyang, LiaoningAges 18 years+ - NCT07244614Recruiting
Study of ustekinumab or apremilast for Behçet's disease symptoms
This study tests if ustekinumab or apremilast can help control Behçet's disease symptoms like mouth and genital ulcers, skin sores, and joint pain. It may be an option if standard treatments haven't worked well.
BordeauxAges 18 years+ - NCT07244952Recruiting
Vojta therapy for posture and trunk control after stroke
This trial tests a type of movement therapy called Vojta Therapy to see if it helps improve posture and trunk control after a stroke. It is for people who had their first stroke within the past 3 months and have significant weakness on one side of the body.
LahoreAges 45–65 - NCT07245069RecruitingPhase 2
Can dapagliflozin protect the heart during breast cancer chemo?
This trial tests if the drug dapagliflozin can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. It aims to see if taking the drug during chemo helps keep your heart healthy.
LjubljanaAges 18 years+ - NCT07245082Recruiting
Type 2 diabetes patient study
This study looks at people with type 2 diabetes to understand their health. If you join, you'll have simple measurements taken like height, weight, and grip strength.
Taipei, Zhongzheng DistAges 18 years+ - NCT07245264RecruitingPhase 2/Phase 3
TXA for preventing return of subdural hematoma
This trial is testing whether giving a medicine called tranexamic acid (TXA) during surgery helps prevent rebleeding after draining a chronic subdural hematoma. TXA helps stop bleeding, and the goal is to reduce the chance the hematoma comes back.
ChandigarhAges 18 years+ - NCT07245680RecruitingPhase 3
Testing two pills vs one for pulmonary hypertension with heart or metabolism issues
This trial compares starting with two oral medications versus one for people newly diagnosed with pulmonary arterial hypertension (PAH) who also have conditions like high blood pressure, diabetes, obesity, or heart disease. The goal is to see if a two-drug approach works better for patients with these additional health issues.
Le Kremlin-BicêtreAges 18 years+ - NCT07246096RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a new CAR-T cell treatment for people with certain autoimmune diseases that have not responded to standard therapies. The treatment uses your own immune cells modified to target and attack disease-causing cells.
ShanghaiAges 18–70 - NCT07246135Recruiting
Leadless Pacemaker Registry: Patient Outcomes
This registry tracks patients who have received a leadless pacemaker at the University Hospital of St. Pölten. It helps doctors learn how well these small, wire-free pacemakers work over time.
Sankt Pölten, Lower AustriaAges 18 years+ - NCT07246148Recruiting
Noninvasive blood pressure monitoring during aneurysm repair
This study compares a new noninvasive blood pressure monitoring method to the standard method (using a small tube in your wrist) during brain aneurysm repair surgery. If you join, you may avoid the need for a wrist artery line.
SeoulAges 19–80 - NCT07246473Recruiting
Non-invasive ultrasound for brain bleed clearance
This trial tests a non-invasive ultrasound device to help clear blood clots from the brain after a spontaneous bleed. It may be an option for people with small to medium-sized bleeds who do not need surgery.
Wuhu, AnhuiAges 18–80 - NCT07246577Recruiting
Improving diagnosis and monitoring in giant cell arteritis
This study uses ultrasound, a biopsy of the temple artery, and blood tests to improve how giant cell arteritis (GCA) is diagnosed, monitored, and predicted. It may help doctors find better ways to manage this condition.
GothenburgAges 18 years+ - NCT07247032Recruiting
Heart failure management with remote monitoring
This trial tests whether remote monitoring of your implanted heart device can help your doctors better manage your heart failure. It is for people with certain types of pacemakers or defibrillators who are willing to share their device data remotely.
ParisAges 18–85 - NCT07247058RecruitingPhase 4
Testing Isturisa for mild cortisol excess from adrenal tumors
This study tests whether a drug called Isturisa (osilodrostat) can safely lower mild cortisol excess in people with adrenal tumors. It aims to help patients avoid the long-term effects of too much cortisol.
Baltimore, MarylandAges 18 years+ - NCT07247669Recruiting
AI phone triage for emergencies
This study tests if artificial intelligence can help identify time-sensitive emergencies like stroke, heart attack, or trouble breathing from recorded phone calls. The goal is to make emergency response faster and more accurate.
Málaga, MálagaAges Any age - NCT07247838Recruiting
Gut bacteria changes in first-time stroke patients
This study looks at how gut bacteria change right after a first-time ischemic stroke. It aims to understand if these changes are linked to recovery or other health factors.
Nantong, JiangsuAges 18 years+ - NCT07248176Recruiting
Universal CAR-T therapy for multiple myeloma
This trial tests a universal CAR-T cell therapy (made from donated cells) for multiple myeloma that has come back after at least two prior treatments. It may be an option if your cancer cells have a specific marker called BCMA and you have not had certain prior therapies.
ShanghaiAges 18 years+ - NCT07248371Recruiting
Validating multi-omics for metabolic syndrome diseases
This study is testing a new way to look at health information (multi-omics) to better understand conditions related to metabolic syndrome, like diabetes or heart disease. It may help doctors find more personalized treatments.
TaoyuanAges 20 years+ - NCT07248618Recruiting
Balance and trunk training for stroke recovery
This study compares two types of physical therapy exercises to see which one better helps stroke survivors improve trunk control, balance, and daily activities. It may be a good fit if you had an ischemic stroke and are between 6 months and 1.5 years into recovery.
Lahore, Punjab ProvinceAges 40–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.