Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT05288894Recruiting
Italian registry for people with repaired Tetralogy of Fallot
This trial is a registry that collects information about people who have had Tetralogy of Fallot (TOF) repaired. It may help doctors better understand long-term outcomes and improve future care.
Ancona, The MarchesAges 10 years+ - NCT05747404Recruiting
3D heart ultrasound study for certain right-heart problems
This study uses a special 3D heart ultrasound to measure how well the tricuspid valve and right side of the heart are working. It may help improve how these conditions are evaluated and followed over time.
MilanAges 18 years+ - NCT06358248Recruiting
Registry for customized endografts in complex aortic aneurysms
This registry tracks patients with complex abdominal aortic aneurysms who receive a physician-modified endograft. It aims to collect data on how well this tailored device works to treat aneurysms that standard grafts cannot handle.
PadovaAges 18–100 - NCT03277365Recruiting
Share your 23andMe data with a digital genetics study
This study tests a digital platform that uses people’s existing genetic information to support genetic research. If you are an adult and willing to share your 23andMe results from an Apple phone, you can likely participate.
La Jolla, CaliforniaAges 18 years+ - NCT05692778Recruiting
Care program for people with diabetes and foot problems
This trial is testing an improved care approach for people with diabetes who have foot complications, delivered through primary care. It may help by organizing care more effectively and supporting better diabetes and foot management.
GothenburgAges 18 years+ - NCT06153147Recruiting
Kidney & blood pressure in childhood cancer survivors
This study looks at kidney health and blood pressure in childhood cancer survivors. If you finished high-risk cancer therapy about 3 years ago, researchers want to see how your kidneys and blood pressure are doing now.
Toronto, OntarioAges Up to 19 years - NCT06171061RecruitingPhase 4
Yangxinshi tablets for better exercise in heart disease
This study tests if Yangxinshi tablets can help people with chronic coronary syndrome (a type of heart disease) walk farther or exercise longer. It's for those whose heart condition limits their daily activity.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06372054Recruiting
Predicting health risks for Italian Air Force members
This study aims to develop smart risk models using your body's data (like proteins and genes) along with personal exposure readings. It will help predict health risks for Italian Air Force personnel. You will wear a monitor and give samples, then be followed over time.
MilanAges 26–38 - NCT01999140Recruiting
ICD and CRT-D device registry for patients worldwide
This trial is a real-world registry that collects information from people who receive an implantable heart defibrillator or related device. It helps doctors understand how these devices are used and how patients do over time.
Washington D.C., District of ColumbiaAges Any age - NCT06116630Recruiting
Brain health after stroke risk factors study
This study looks at how well the brain works after a stroke or in people with stroke risk factors. It uses a special MRI scan to understand brain changes that may affect thinking and memory.
Palo Alto, CaliforniaAges 45–90 - NCT05632432Recruiting
Heart tissue grafts to help the heart after surgery
This trial tests whether transplanting tiny heart “micrografts” from the left heart chamber area can improve heart function after cardiac surgery. It is meant for people with weakened heart pumping and heart failure symptoms despite medicine.
Helsinki, UusimaaAges 18–75 - NCT06257043Recruiting
Real-world study of aortic valve replacement
This trial is studying how well a new type of heart valve works in real-life patients with aortic valve disease. It will help doctors understand if this valve is safe and effective for people who need a procedure called TAVR (transcatheter aortic valve replacement).
Xi'an, ShaanxiAges 18 years+ - NCT06087848RecruitingPhase 1/Phase 2
StromaForte stem cell therapy for heart event prevention
This trial tests a stem cell product called StromaForte to see if it can reduce cardiovascular events like heart attacks in people with stable medical conditions. It may help if you have heart or blood vessel issues that have been stable for at least six months.
Nassau, The BahamasAges 25–85 - NCT06371170Recruiting
Rivaroxaban for heart clots in children
This study tests a blood thinner called rivaroxaban in children who have a blood clot inside the heart. The goal is to see if it safely and effectively dissolves the clot, potentially avoiding the need for stronger treatments.
Ancona, The MarchesAges 1 month–16 years - NCT06376630Recruiting
Esmolol for heart protection during heart attack
This study tests if giving a fast-acting heart medication (esmolol) early through an IV can protect the heart muscle during a heart attack. It may help patients who cannot receive a standard treatment due to certain risks.
MoscowAges 18 years+ - NCT06379386Recruiting
Long-term results of TAVR for severe aortic valve regurgitation
This trial follows people who have severe aortic valve regurgitation and get a TAVR. It looks at how well the valve works over time and how patients do in the long run.
Xi'an, ShannxiAges 18 years+ - NCT06377878Recruiting
The Preeclampsia Registry
This study is building a registry of people who have had preeclampsia or related high blood pressure disorders during pregnancy, as well as their family members and healthy volunteers. The goal is to collect information that can help researchers better understand these conditions and improve care.
Melbourne, FloridaAges 13 years+ - NCT04522622RecruitingPhase 4
Teriparatide for low bone turnover in advanced kidney disease
This trial tests teriparatide (a hormone-like bone medicine) to improve bone health in people with advanced chronic kidney disease who are at risk for weak, low-turnover bone. It may help by changing how quickly your bones break down and rebuild.
AalborgAges 18–120 - NCT06009874Recruiting
SGLT2 inhibitor early after heart attack to protect the heart
This study tests whether giving an SGLT2 inhibitor (a diabetes medicine that may also protect the heart) early after a heart attack can help shield the heart from damage. It is for people having a first-time STEMI heart attack who have adequate kidney function and stable blood pressure.
Shibīn al Kawm, MenofiaAges 18–80 - NCT05264831Recruiting
Ablation treatment after failed electric heart shock
This trial tests whether blocking faulty heart signals from the pulmonary veins (with or without additional “substrate” modification) works better when electric cardioversion doesn’t stop persistent atrial fibrillation. It may help people who remain in atrial fibrillation after cardioversion by reducing symptoms and abnormal rhythm over time.
Caluire-et-CuireAges 18–80 - NCT05878912Recruiting
Obesity and weight loss in certain heart failure patients
This study looks at how higher body weight and weight loss affect people who have heart failure with preserved pumping strength. It uses heart scans to measure how the heart and body change, which may help guide future treatment plans.
OxfordAges 18–85 - NCT06381271Recruiting
TAVR for severe aortic valve regurgitation
This trial tests a procedure called TAVR to replace the aortic valve in people with severe aortic regurgitation (a leaky valve). It may help you if you have this condition and prefer a less invasive option than open-heart surgery.
Xi'an, ShannxiAges 18 years+ - NCT06383208Recruiting
Heart and kidney risk study for people with both diseases
This study looks at how well we can predict heart and kidney problems in people who have both coronary heart disease and chronic kidney disease. By analyzing certain markers, researchers hope to create a better risk assessment tool.
Beijing, Beijing MunicipalityAges 18–80 - NCT03749980Recruiting
Study following people with von Hippel-Lindau (VHL)
This study follows people who have von Hippel-Lindau (VHL) over time to better understand how the condition changes. It may help doctors plan future treatments by collecting long-term health information.
Boston, MassachusettsAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.