Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,062 recruiting studies in this area right now.
By phase
- Not applicable8,033
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure567
- Hypertension402
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction98
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California466
- Alabama199
- Massachusetts182
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Minnesota120
- Texas120
Recruiting studies10,059 total
- NCT07010250Recruiting
Kidney Energy Use and Scarring in ANCA Vasculitis
This study looks at how kidney cells use energy and how that leads to scarring in people with ANCA vasculitis. It compares findings with people who have other kidney diseases to better understand and possibly treat kidney damage.
ParisAges 18–90 - NCT04880265Recruiting
Study heart rhythm changes after open-heart surgery
This study looks at how often and how long an irregular heartbeat (atrial fibrillation) happens after planned open-heart surgery. It aims to better understand the “burden” of this rhythm problem, which could help improve care for future patients.
Boston, MassachusettsAges 20–90 - NCT07335861Recruiting
Hyalomatrix for healing venous leg ulcers
This trial tests a special gel-like dressing (Hyalomatrix) to see if it helps heal leg ulcers caused by poor blood flow in the veins. It may be a good option if you have a chronic venous leg ulcer that hasn't healed much despite standard care.
Alexandria, LouisianaAges 18 years+ - NCT05733676Recruiting
MI Paste Plus vs resin for white spots after braces
This trial compares two tooth treatments to see which one works better for “white spot” areas that can appear after braces come off. If you have mild plaque buildup and at least one white spot on front teeth, you may be eligible to test one of these options and improve tooth surface healing.
Edmonton, AlbertaAges 12–21 - NCT07656454RecruitingPhase 1
Comparing two ways to give CDR132L in healthy volunteers
This study measures how well the drug CDR132L enters the blood when injected under the skin, compared to injection into a vein. It is done in healthy volunteers to find the best way to give the drug.
BerlinAges 18–55 - NCT07115953Recruiting
Spiral nerve treatment for uncontrolled high blood pressure
This trial tests a new procedure to treat high blood pressure by using a special catheter to calm overactive nerves in your kidneys. It may help you achieve better blood pressure control if medications are not enough.
MelbourneAges 18 years+ - NCT05851209Recruiting
Study biomarkers in people with moderate aortic valve narrowing
This study looks at blood and/or body signals (called biomarkers) to understand why aortic valve narrowing may worsen and what outcomes people have. You may be able to help researchers by undergoing regular heart care plus additional testing like MRI or CT if you qualify.
BonnAges 18 years+ - NCT06813339RecruitingEarly Phase 1
Testing a new drug in healthy people and those with heart condition
This trial tests a new medicine called UDP-003 in two groups: healthy volunteers and people who had a heart event (acute coronary syndrome) at least a year ago. The goal is to see if the drug is safe and how the body handles it, which could lead to better treatments for heart disease.
Adelaide, South AustraliaAges 18–79 - NCT07075588Recruiting
Food and coaching to lower blood pressure for Black and Hispanic adults
This study tests a program that helps people manage their blood pressure by offering healthy food choices, personal diet coaching, and text messages that match your culture. It's for Black/African American or Hispanic/Latino adults living in certain low-income areas of Maryland.
Baltimore, MarylandAges 21–70 - NCT07674758Recruiting
Understanding heart risk in Duchenne and Becker muscular dystrophy
This study looks at heart health in people with Duchenne or Becker muscular dystrophy to find better ways to predict and track heart problems. The goal is to improve future treatment trials.
Sacramento, CaliforniaAges Any age - NCT03529019RecruitingEarly Phase 1
Nutrition study for poor blood flow to a limb
This early-phase study looks at how nutrition affects people who have very poor blood flow to a limb (critical limb ischemia). It’s exploring whether nutrition changes health outcomes and safety for this condition.
Boston, MassachusettsAges 18–99 - NCT06315192Recruiting
Stroke alarm app trial for faster care
This trial tests a smartphone app called Stroke Alarm to see if it helps people who have had a recent stroke, mini-stroke, or have untreated atrial fibrillation get faster care. You may be eligible if you are 50 or older, have a smartphone, and had a relevant event in the last 2 weeks.
GothenburgAges 18 years+ - NCT06735534Recruiting
Repeat ablation for persistent atrial fibrillation with pulsed field
This trial tests a newer type of ablation (pulsed field ablation) for people with persistent atrial fibrillation who have already had one ablation. The goal is to see if it can fix the heart rhythm problem again.
Mobile, AlabamaAges 18 years+ - NCT06103838RecruitingPhase 2
Fluciclovine PET/CT scan for multiple myeloma
This trial tests whether a special PET/CT scan (using fluciclovine, a radioactive tracer) can more clearly see multiple myeloma in the body. It may help doctors evaluate the extent of the disease and guide treatment decisions.
Bethesda, MarylandAges 18–120 - NCT07676578Recruiting
Virtual reality walking rehab for recent stroke patients
This study tests if using a virtual reality headset during walking exercises can help people who had a stroke within the past 1 to 6 months improve their walking. You might be able to join if you can walk a bit but still need help or practice, and your doctor approves.
Indianapolis, IndianaAges 18 years+ - NCT05595954Recruiting
Personalized anesthesia plan to protect the brain during heart surgery
This trial studies whether tailoring anesthesia and monitoring the brain’s blood-flow control during heart surgery can improve neurological outcomes (brain-related function and recovery). It may help by guiding anesthesia in a more individualized way and checking how well the brain is protected during the operation.
BaselAges 65 years+ - NCT06512883RecruitingPhase 3
Testing benralizumab in children with eosinophil diseases
This trial tests a medicine called benralizumab for children with specific eosinophil-driven diseases (EGPA or HES). It aims to see if the drug can help control these conditions.
Aurora, ColoradoAges 6–17 - NCT05478213Recruiting
Study how ventricular tachycardia happens in heart disease
This study looks at what causes a dangerous fast heart rhythm (ventricular tachycardia) in people with ischemic cardiomyopathy and an implanted defibrillator. The goal is to better understand the rhythm so doctors can improve treatment, especially around procedures like catheter ablation.
Atlanta, GeorgiaAges 18 years+ - NCT07614659Recruiting
Heart health screening for adults in Uppsala, Sweden
This study invites residents of Uppsala, Sweden who are turning 50, 55, 60, 65, 70, or 75 to participate in cardiovascular (heart and blood vessel) health screening. The goal is to help identify heart health risks early so you can take steps to stay healthy.
UppsalaAges 50–75 - NCT07550296RecruitingPhase 2
Second IV Clot-Dissolving Treatment for Major Stroke
This trial tests giving a second dose of an IV clot-dissolving medicine (prourokinase) to patients who had a stroke from a large clot but didn't improve enough after the first dose. The goal is to see if a second dose within 6 hours of stroke onset can help more patients recover.
Shenyang, None SelectedAges 18–80 - NCT07500480Recruiting
Home use of a wearable grasping device after stroke
This trial tests if a wearable device that helps open and close the hand can be used at home by people who have weakness after a stroke. It may help improve your ability to grasp objects like a glass or spoon.
ToulouseAges 18 years+ - NCT03215849Enrolling by invitation
Tested pacing device for heart failure with preserved pumping
This trial studies a heart pacing approach in people with heart failure symptoms despite preserved heart pumping. It aims to see whether changing heart timing can improve how you feel and how your heart works during exercise.
CardiffAges Any age - NCT03197363Enrolling by invitation
Long-term study of adults living in Białystok
This study follows adults living in Białystok over time to learn about health and life patterns. If you’re invited to take part and agree, it may help researchers better understand community health.
BialystokAges 20–80 - NCT03253835Enrolling by invitation
MRI heart flow study to understand heart muscle damage
This study uses a special heart MRI to look at blood-flow patterns and how they relate to heart muscle injury. It may help researchers better understand different types of heart damage by comparing people with and without injury.
Graz, StyriaAges 20–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,062 recruiting cardiology studies from the U.S. registry right now, out of 15,523 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.