Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT05345431Recruiting
Check whether a leg-artery nerve procedure helps poor circulation
This trial looks at whether endovascular denervation (a catheter-based nerve-targeting procedure inside blood vessels) can improve symptoms and circulation in people with peripheral arterial disease (PAD). It may help if you have PAD that causes walking problems or ongoing lower-leg symptoms.
Nanjing, JiangsuAges 18–75 - NCT03380195Recruiting
Watermelon juice study on heart recovery and muscle soreness
This study tests whether drinking watermelon juice affects how quickly your heart rate returns to normal after exercise and how sore your muscles feel afterward. It’s for generally healthy adults and may help researchers understand how diet changes exercise recovery.
San Diego, CaliforniaAges 21–50 - NCT02860364Recruiting
Checking different cooling levels during part of heart surgery
This trial compares two cooling temperatures during an “aortic hemiarch” operation to see which approach is safer and better for brain protection. It may help guide surgeons on the best cooling strategy for some planned heart surgeries.
Boston, MassachusettsAges 18 years+ - NCT06575556Recruiting
Using MRI instead of CT for follow-up after Ross procedure
This study compares MRI scans to CT scans for following up patients who had the Ross procedure (a type of heart valve surgery) using the 'loose jacket' technique. The goal is to see if MRI can successfully replace CT, avoiding the radiation and dye used in CT scans.
AswānAges Any age - NCT03592290Recruiting
Testing blood-flow monitoring during controlled fluid loss
This study tests how well doctors can monitor your circulation (blood flow) while they carefully cause a temporary, controlled drop in blood volume. It may help improve monitoring methods in future medical situations.
New Haven, ConnecticutAges 20–45 - NCT03635255Recruiting
Testing heart disease blood markers to predict heart events
This study looks at tiny molecules in your blood to see how they relate to future heart problems in people with coronary artery disease or other cardiovascular disease. If your results suggest higher or lower risk, it may help doctors better predict who could have adverse cardiovascular outcomes.
TaipeiAges 20 years+ - NCT03393169Recruiting
Tracking complications after heart surgery in adults
This study looks at how often and why complications happen after heart surgery, using information from the hospital stay. It may help improve care by understanding postoperative risks and outcomes.
ParisAges 18 years+ - NCT05724836Recruiting
Carotid artery narrowing treatment follow-up at clinic
This study follows people who are getting a procedure for carotid artery narrowing at the clinic. It aims to learn about outcomes after these treatments.
Jacksonville, FloridaAges 18 years+ - NCT02728479Recruiting
Registry for people getting angioplasty
This study is a registry that collects information from people who are having a balloon procedure to open blocked blood vessels (angioplasty). It may help doctors understand outcomes and care patterns, but it usually does not change your treatment.
DüsseldorfAges 18 years+ - NCT02622542Recruiting
Stent repair versus best medical care for type B dissection
This trial compares an endovascular stent (placed through blood vessels) to best medical therapy (blood pressure and pain control) for certain “uncomplicated” type B aortic dissections. It aims to see which approach works better in the early period after symptoms start.
Houston, TexasAges 18 years+ - NCT02301663Recruiting
Stress test study of heart blood-flow issues in adults
This study tests a new kind of stress test to understand how small blood-vessel heart problems relate to heart relaxation problems in people with angina (chest pain) but no blocked arteries. It may help doctors learn better ways to diagnose and guide treatment for these conditions.
Los Angeles, CaliforniaAges 18–60 - NCT05383287Recruiting
Study of heart failure with preserved pumping function
This study looks at the different features and patterns of people with heart failure where the heart’s pumping strength is preserved. It may help doctors better understand your type of heart failure and tailor care.
ManchesterAges 18 years+ - NCT02918032Recruiting
Registry study for triglyceride storage heart and blood vessel disease
This is a registry study that collects health information from people diagnosed with neutral lipid storage disease (NLSD) or triglyceride deposit cardiomyovasculopathy (TGCV). It may help researchers better understand the condition and improve future care plans.
Stanford, CaliforniaAges Any age - NCT02914808Recruiting
Study for leg swelling caused by lymph or vein problems
This trial studies how to measure and possibly treat swelling in the legs caused by long-term lymph or vein blockage (primary or secondary lymphoedema, or PTS). It’s looking at people with one type of leg swelling in one leg, and it checks whether MRI scans can be used safely.
Grenoble, IsèreAges 18–99 - NCT05138718Recruiting
FDG heart scan study for people after a heart attack
This trial studies people who had a heart attack more than 90 days ago using an FDG PET/CT scan of the heart. It may help doctors learn more about what the scan shows and how it could be useful after heart attacks.
Boston, MassachusettsAges 18–80 - NCT02444416Recruiting
Registry study for people with new acute heart failure
This study is a registry that collects information about people who come to care with sudden (acute) worsening heart failure symptoms. If your test shows a higher BNP level, your doctors may use your details to better understand and track acute heart failure care.
GenevaAges 16–100 - NCT02600936Recruiting
Vein stent registry study for adults with blocked vein flow
This is a registry (a study that tracks patient information) for adults who get a vein stent to improve blocked blood flow in major veins. It may help doctors better understand how vein stents are used for these problems over time.
New York, New YorkAges 18 years+ - NCT05534971RecruitingPhase 4
Testing safer ultrasound-guided central line placement in the ER
This Phase 4 study looks at how to place a large IV line (called a central line) in the emergency department using ultrasound guidance. It may help patients by improving how safely and effectively these lines are placed, especially in urgent situations.
The Bronx, New YorkAges 18 years+ - NCT04871568Recruiting
Compare two sites for dialysis catheter placement
This trial tests whether placing a dialysis catheter in one location (subclavian/near the collarbone) is as good as placing it in another (jugular/neck) for patients who need a temporary dialysis catheter. It aims to reduce problems like vein narrowing caused by catheter placement.
LundAges 18 years+ - NCT05089162Recruiting
Testing a heart ultrasound approach in chronic heart failure
This study looks at people with chronic heart failure with weaker pumping function and checks how well a lung/heart ultrasound can assess congestion (fluid buildup). If you qualify, you may help test a better way to evaluate your condition during a planned hospital visit.
Vandœuvre-lès-NancyAges 18 years+ - NCT02282748Recruiting
Swiss long-term health study for local residents
This trial is a long-term study that follows people over time to learn about health patterns in specific Swiss areas. Your participation may help researchers better understand long-term health changes and how to improve care.
Uznach, Canton of St. GallenAges 6 years+ - NCT04822649Recruiting
Assessing exercise capacity in people with heart microvascular problems
This study looks at how well you can exercise and how your body composition relates to tiny blood-vessel problems in the heart. It may help doctors better understand symptoms and function in people who don’t have major blockages in the large heart arteries.
SeoulAges 20–80 - NCT05483465RecruitingPhase 4
NAD supplement trial for brain blood vessel health in aging
This trial studies whether taking an NAD supplement can support brain blood vessel health as people age. Participants will be tested for brain and health changes and may help researchers understand how to keep the brain’s blood vessels healthier over time.
Oklahoma City, OklahomaAges 60–85 - NCT05609097Recruiting
Exercise program study for older adults with weaker heart pumping
This study tests a new exercise program for people over 65 with heart failure where the heart pumps less efficiently. The goal is to see if tailored exercise is safe and helpful for breathing, energy, and daily function.
Charlottesville, VirginiaAges 65 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.