Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,073 recruiting studies in this area right now.
By phase
- Not applicable8,041
- Phase 2490
- Phase 4483
- Phase 3452
- Phase 1359
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke855
- Heart Failure565
- Hypertension403
- Cardiovascular Diseases389
- Coronary Artery Disease375
- Multiple Myeloma330
- Atrial Fibrillation273
- Ischemic Stroke200
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida146
- Maryland120
- Texas120
- Illinois119
- Minnesota119
Recruiting studies10,070 total
- NCT07503301Enrolling by invitation
Study on stroke recovery and limb therapy
This trial tests if a limb therapy called RIC can help people recover from a stroke caused by small vessel disease. It is designed for people aged 50-65 who have had a recent stroke and have few other health issues.
Hangzhou, ZhejiangAges 50–65 - NCT07499128Enrolling by invitation
Continuous temperature monitoring for cytokine release syndrome
This study tests a wearable device that continuously monitors your body temperature to detect cytokine release syndrome, a possible side effect of certain immunotherapies. The goal is to catch it early so you can get treatment faster.
Bethesda, MarylandAges 18–120 - NCT07498764Enrolling by invitation
Virtual care after cardiac arrest recovery program
This trial tests a virtual care program to help people recover after cardiac arrest. It offers follow-up support through video or phone sessions.
Basildon, EssexAges 18 years+ - NCT07495410Enrolling by invitation
Exercise training for Anderson-Fabry disease
This study tests whether a supervised exercise and physiotherapy program can improve fitness, stamina, and daily life for people with Anderson-Fabry disease. It is designed for people who are medically stable and able to join a gentle, progressive training program.
PragueAges 18 years+ - NCT07491744Enrolling by invitation
Stroke and TIA study on heart and blood vessel health
This study looks at the causes of stroke and TIA by doing extra tests on patients admitted to the hospital. It aims to better understand and prevent future heart and blood vessel problems.
Stockholm, Stockholm CountyAges 18 years+ - NCT07489612Enrolling by invitationPhase 2
Testing QLS1410 for people with hard-to-control high blood pressure
This trial is testing an experimental drug, QLS1410, to see if it can lower blood pressure in people whose blood pressure is still high even after taking two or more medications.
JinanAges 18 years+ - NCT07487714Enrolling by invitationPhase 4
Comparing amiodarone doses for paroxysmal AF
This study compares three different daily doses of the heart rhythm medication amiodarone to find the most effective one for preventing episodes of paroxysmal atrial fibrillation. Participants will take one of three doses (100, 200, or 400 mg) for up to 12 months, and the study will monitor how well each dose controls the irregular heartbeat.
TomskAges 18–80 - NCT07485816Enrolling by invitation
Heart-brain oxygen and thinking changes in heart failure
This study looks at how well your heart and brain work together to use oxygen, and how that relates to changes in thinking and memory for people with heart failure.
Kunming, YunnanAges 18–70 - NCT07484958Enrolling by invitation
Co-designing a stroke rehab trial toolkit
This study asks stroke survivors, their families, and healthcare staff to help create a toolkit that makes it easier to run stroke rehabilitation clinical trials. Your input will improve how future trials are designed.
Plymouth, DevonAges 18 years+ - NCT07478406Enrolling by invitation
Pelvic floor and vein health connection study
This study looks at how pelvic floor muscles relate to leg vein problems (venous insufficiency). You may benefit if you have vein issues and are willing to try telerehabilitation.
Istanbul, IstanbulAges 30–65 - NCT07475611Enrolling by invitation
Screen-based rehab for visual neglect after stroke
This study tests whether an interactive screen helps people with left-sided neglect after a stroke. It includes adults who had a right-sided stroke and have trouble paying attention to the left side of their world.
Buenos Aires, EscobarAges 18–88 - NCT07468123Enrolling by invitation
Estimating Atrial Fibrillation Risk With a Handheld ECG
This trial uses a simple, handheld ECG device (like a small card) to check your risk for atrial fibrillation, a common irregular heartbeat. You'll record short heart tracings at home, and the study team will review them to find hidden risk factors.
Boston, MassachusettsAges 18–90 - NCT07460219Enrolling by invitation
Pharmacist-led heart failure medication study for VA clinics
This trial tests if pharmacists in VA regions can help adjust heart failure medications. It may improve how patients are treated.
Palo Alto, CaliforniaAges 18 years+ - NCT07458308Enrolling by invitation
Blended care vs. traditional rehab after stroke or brain injury
This trial compares a new approach that combines in-person therapy with digital support to standard outpatient rehabilitation for people recovering from stroke or brain injury. The goal is to see if blended care works as well or better than traditional rehab.
LucerneAges 18–80 - NCT07456826Enrolling by invitationPhase 4
Comparing two eye numbing gels for shots
This trial tests a new eye-numbing gel against the standard numbing method to see which works better for patients getting regular anti-VEGF injections in the eye.
Tyler, TexasAges 18 years+ - NCT07456085Enrolling by invitationPhase 3
Rivaroxaban vs warfarin for mechanical heart valves
This trial compares a newer blood thinner (rivaroxaban) to the standard one (warfarin) for people with mechanical heart valves who have had clots or bleeding while on warfarin, or who cannot easily monitor their INR levels. It aims to see if rivaroxaban is safer and more effective.
Rawalpindi, Punjab ProvinceAges 18 years+ - NCT07446244Enrolling by invitation
Catheter ablation for advanced atrial fibrillation
This trial tests a special type of catheter ablation (using electric pulses called electroporation) to treat people with long-lasting atrial fibrillation and a very enlarged left atrium. It may offer a new treatment option when standard approaches are limited.
Ljubljana, OsrednjaslovenskaAges Up to 80 years - NCT07445347Enrolling by invitation
Bevacizumab for severe HHT liver issues with high heart output
This study looks at how well the drug Bevacizumab works and how safe it is for people with HHT who have severe liver problems that cause their heart to pump too much blood. It aims to help doctors understand if this treatment can help manage these serious symptoms.
PoitiersAges 18 years+ - NCT07445204Enrolling by invitation
Electrical stimulation for swallowing after stroke
This trial tests whether a gentle electrical stimulation technique on neck muscles can help improve swallowing in people who recently had a stroke. It may be a good option if you are still having trouble swallowing after your stroke.
IstanbulAges 18 years+ - NCT07442448Enrolling by invitationPhase 4
Study of Finerenone for heart and kidney health in diabetes
This trial tests a medication called Finerenone to see if it can improve heart structure and function in people with both diabetic kidney disease and heart failure. If you have type 2 diabetes, kidney problems, and heart failure with preserved pumping function, this study may explore a new treatment option for you.
TaipeiAges 18 years+ - NCT07438054Enrolling by invitation
Yearly heart-rhythm screening for adults 65 and older
This study tests whether monthly heart checks using a simple ECG (a quick test of your heart's electrical activity) can find a common heart-rhythm problem called atrial fibrillation earlier. You would visit your family health center once a month for 12 months to get the ECG done, no extra procedures or treatments are involved.
Ordu, OrduAges 65 years+ - NCT07431437Enrolling by invitation
GENOSS paclitaxel balloon for leg artery disease
This trial tests a special balloon coated with paclitaxel (a drug that helps keep arteries open) in people with narrowed or blocked leg arteries. It aims to see how well the balloon works over one year.
SeoulAges 19–85 - NCT07426354Enrolling by invitation
Sensory feedback and mirror therapy for stroke recovery
This trial tests whether combining sensory feedback with mirror therapy can help people who have had a stroke improve arm movement. It may be a good option if you are at least three months past your stroke and have some but limited arm function.
New Taipei CityAges 20–85 - NCT07424976Enrolling by invitation
Early brain injury detection after infant heart surgery
This study looks for early signs of brain injury in infants after heart surgery that uses a heart-lung machine. It aims to improve monitoring and care for babies with congenital heart disease.
LjubljanaAges 1 week–1 year
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,073 recruiting cardiology studies from the U.S. registry right now, out of 15,588 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Mental health
- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.