Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT06583876Recruiting
A new device for leaky mitral valves without open-heart surgery
This trial tests a new device for people whose mitral valve leaks badly (grade 3+ or 4+) and who are not candidates for surgery. The device aims to fix the leak through a less invasive approach, and the study checks if it's safe and works well in daily life.
BudapestAges 18 years+ - NCT06923267Recruiting
Ultrasound to check heart function during breathing trials
This trial tests if using ultrasound to monitor your heart during a breathing test can help predict if you will need the breathing tube again. It is for people on a ventilator for at least 24 hours who are at higher risk of needing the tube reinserted.
OrléansAges 18 years+ - NCT07396636Recruiting
Using machine learning to manage low blood pressure during surgery
This study tests whether an AI tool can help doctors better manage low blood pressure during planned surgeries. If you are having an elective surgery with general anesthesia and need an arterial line for monitoring, this trial may be for you.
Konya, Konya/MeramAges 18 years+ - NCT06431425Recruiting
Online genetic counseling clinic for inherited heart conditions
This trial tests an online genetic counseling clinic for people with certain inherited heart muscle diseases and their family members. It aims to provide presymptomatic counseling (before symptoms appear) through video calls, making it easier to access care from home.
Utrecht, UtrechtAges 18–90 - NCT06888284Enrolling by invitation
Tuijing therapy for depression and heart rate
This trial tests whether Tuijing therapy, a non-invasive treatment, can improve heart rate variability and reduce depression symptoms in people who have been feeling depressed for over three months. It may be an option if you haven't used other treatments recently.
Hong KongAges 18–60 - NCT07392281RecruitingEarly Phase 1
Macitentan for chest pain from small heart vessel issues
This study tests a medicine called macitentan to see if it helps people with chest pain caused by problems in the tiny heart blood vessels (not from big blockages). If you have angina but no major artery blockages, this trial might explore a new treatment option.
Beijing, Beijing MunicipalityAges 18–75 - NCT07390695Enrolling by invitation
Gamified exercise for hardcore smokers who are inactive
This trial tests if a fun, game-like exercise program can help heavy smokers who don't exercise much improve their heart and lung fitness and feel more ready to quit smoking.
Yogyakarta, Special Region of YogyakartaAges 17–45 - NCT06813859Recruiting
Can exercise during pregnancy help your baby's heart rate?
This trial uses a wireless monitor to track the baby's heart rate while you exercise. The goal is to learn how physical activity affects the baby in healthy expectant mothers.
Zurich, Canton of ZurichAges 18–45 - NCT07382284Recruiting
Long-term survival after LVAD for end-stage heart failure
This trial looks at how well people with advanced heart failure do over the long term after getting a left-ventricular assist device (LVAD). Researchers will check blood and heart tissue samples to learn more about recovery and outcomes.
Nanjing, JiangsuAges Any age - NCT07379970Recruiting
Wearable devices and coaching for adults with central obesity
This study tests whether wearing a fitness tracker and getting health coaching by phone or video can help adults with central obesity become more active and improve their heart health. It lasts for 6 months and is run by the University of Hong Kong.
Hong KongAges 40 years+ - NCT06950242Enrolling by invitation
Laser balloon for narrowed brain arteries
This trial tests a new laser balloon catheter to widen narrowed arteries in the brain that cause stroke symptoms. It may help if you have a severely blocked artery and are healthy enough for the procedure.
Changzhou, JiangsuAges 18–80 - NCT07376616Recruiting
Heart health study during pregnancy and after birth
This study looks at how the heart adapts during pregnancy and the months after giving birth. It uses simple tests to measure heart rate and blood flow, which may help doctors better understand normal changes and identify risks early.
Vigo, PontevedraAges 18 years+ - NCT03815123Recruiting
Study of cardiac CT scans ordered by your doctor
This study enrolls people who are referred by their physician for a heart CT scan (a test that takes detailed pictures of the heart). It helps researchers understand how these scans are performed and used in routine care.
Heidelberg, Baden-WurttembergAges Any age - NCT05954507Recruiting
PET/MRI scan to assess heart risk in sarcoidosis
This study checks whether a special heart scan called PET/MRI can predict how sarcoidosis may affect your heart. It may help doctors better estimate heart risk and plan follow-up based on scan findings.
CréteilAges 18 years+ - NCT07372040RecruitingPhase 2
Adding a Water Pill for Heart Failure in the Hospital
This trial tests if adding a diuretic (water pill) called acetazolamide to usual care can help you get rid of extra fluid faster while you are in the hospital for worsening heart failure.
TantaAges 18 years+ - NCT07370103Recruiting
Predicting low blood pressure in liver disease patients after anesthesia
This study uses an ultrasound to measure blood flow in the neck's main artery to see if it can predict a dangerous drop in blood pressure after you are put to sleep for surgery. It is for adult patients with chronic liver disease who are having planned surgery.
CairoAges 18 years+ - NCT05960474Recruiting
Study registry for coronary microvascular disease
This trial is a registry, meaning it mainly collects information about people with coronary microvascular disease. It may help researchers better understand the condition and how it affects daily health and treatment needs.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06977139Recruiting
Structural Heart Disease Registry Study in Lubeck
This study collects information from people with structural heart disease to learn more about their condition and treatments. It does not test a new drug or procedure—just observes your regular care.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT05954832Recruiting
Monitoring heart function and blood flow during general anesthesia
This study checks how heart function and blood flow change in adults while they receive general anesthesia for surgery. It may help doctors better understand what happens to the heart during anesthesia and adjust care for safety.
New York, New YorkAges 18 years+ - NCT05927233RecruitingPhase 4
Methylprednisolone in children after open-heart surgery
This trial tests whether giving methylprednisolone (a steroid medicine) can lower the body’s inflammatory response in children during the first day after congenital open-heart surgery. It may help reduce harmful inflammation and improve recovery for some children undergoing their first surgery.
Karachi, SindhAges 1 month–18 years - NCT07366164Recruiting
AI-guided blood flow study for high-risk colorectal surgery
This trial tests whether an artificial intelligence system can better manage blood flow (hemodynamics) in patients with significant health risks undergoing laparoscopic colorectal surgery. It may help improve recovery and reduce complications.
Roma, RMAges 18 years+ - NCT07350629Recruiting
Checking heart valve disease with a finger sensor
This study uses a finger sensor to measure artery waves to assess heart valve problems like aortic regurgitation or stenosis. If you have one of these conditions or are a healthy volunteer, you may help improve noninvasive heart disease detection.
Hefei, AnhuiAges 18–80 - NCT07363993Recruiting
Heart flow and pumping in athletes vs. non-athletes
This study uses 3D ultrasound to see how the heart moves blood in people who exercise a lot versus those who do not. It could help understand how regular endurance training changes heart function.
AvignonAges 18–45 - NCT07446023Recruiting
Testing a new way to measure heart artery blockages
This study compares two advanced imaging methods (IVUS and FFR) to see which better identifies blockages that need treatment. It may help doctors decide the best care for people with chest pain or recent heart attacks.
Beijing, Beijing MunicipalityAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.