Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,610 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3437
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke796
- Heart Failure534
- Hypertension389
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease84
- Peripheral Arterial Disease80
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California451
- Alabama195
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois111
Recruiting studies9,610 total
- NCT07741305Recruiting
Comparing heart ultrasound imaging methods for heart failure
This study tests whether a 3D ultrasound of the heart gives better information than a standard 2D ultrasound in people with heart failure. It aims to improve how doctors measure heart function, which could help guide treatment.
Bari, BAAges 18 years+ - NCT07747896Recruiting
Coordinated primary care team for hard-to-heal wounds
This trial tests whether a team of different healthcare professionals working together in your primary care clinic can help heal stubborn wounds (ulcers) that have not healed with standard care. If you join, you may get more coordinated care and support to help your wound heal.
HillerødAges 18 years+ - NCT07742488Recruiting
Statins and hormone therapy for cholesterol in menopause
This study looks at whether taking statins (cholesterol-lowering medicine) along with hormone replacement therapy (HRT) affects blood clotting in women going through menopause who have high cholesterol. It may help doctors understand how these medicines work together.
Pisa, ItalyAges 45–55 - NCT07741383Recruiting
Combined procedure for severe mitral regurgitation and atrial fibrillation
This study tests whether combining a valve repair procedure with a heart rhythm reset procedure is safe and effective for people with severe mitral regurgitation and atrial fibrillation. It may help improve heart function and reduce symptoms.
Hangzhou, ZhejiangAges 18 years+ - NCT07743021Recruiting
Blood sample study for better health screening
This study collects blood samples and health information over time to improve early detection of diseases. It may help researchers find ways to prevent serious conditions.
BalatonfüredAges 40 years+ - NCT07746336RecruitingPhase 4
Guiding heart ablation with 3D heart mapping
This trial tests a new heart-mapping technique to help doctors treat a fast heart rhythm caused by heart disease. It might improve the precision of the procedure, making it safer and more effective for patients with this condition.
BarcelonaAges 18–99 - NCT06025149Recruiting
Study of a New Biological Heart Valve 'UniLine'
This study tests a new biological heart valve called 'UniLine' for people who need to replace their mitral valve (the valve between the left heart chambers) or aortic valve (the main valve sending blood to the body) for the first time. If you qualify, you would have planned surgery (not an emergency) and need to be free of certain other serious health conditions.
Kemerovo, Kemerovo OblastAges 18–80 - NCT05761067Recruiting
Trial for advanced heart weakness with low pumping ability
This study looks at treatment options for adults with significantly reduced heart pumping strength and extensive coronary artery disease. It may help people who are at higher risk due to widespread blocked heart arteries, but eligibility depends on recent heart events and bleeding risk.
GothenburgAges 18 years+ - NCT06521047Recruiting
Long-term follow-up for EXCELLENT trial participants
This study looks at the long-term health of people who took part in the EXCELLENT trial. If you finished that trial within the last 10 years, you may be able to join this study to help researchers understand how participants are doing over time.
Mulhouse, FranceAges 18 years+ - NCT06581640RecruitingPhase 2
BCMA-targeting CAR-T cells for relapsed/refractory myeloma
This trial tests a new type of immune cell therapy (CAR-T cells) that targets a protein called BCMA on multiple myeloma cells. It is for people whose myeloma has come back or has not responded to other treatments.
Xiamen, FujianAges 18–80 - NCT06611787Recruiting
Registry study for congenital heart disease
This study collects information from people with congenital heart disease (a heart problem you're born with) over their entire life to better understand the condition and improve future care.
Beijing, Beijing MunicipalityAges Any age - NCT06330818Recruiting
Imaging study for Moyamoya disease
This study tests different brain imaging methods (MRI and PET/CT) to better understand blood flow and disease activity in people with Moyamoya disease. The goal is to learn more about the condition and possibly find new ways to see how active the disease is.
Tübingen, Baden-WurttembergAges 18–80 - NCT03998319RecruitingPhase 3
Testing low-dose clot-busting drug after heart attack stent
This trial tests whether a low-dose clot-busting medicine placed into the heart artery after a primary stent can improve outcomes in people with a certain type of heart attack. It also involves short hospital follow-ups and a heart MRI to look at how the heart is recovering.
Bankstown, New South WalesAges 18 years+ - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT06620705Recruiting
Pacing options for AF with low heart function
This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
Aarhus N, Aarhus NAges 18 years+ - NCT05741905Recruiting
Levofloxacin antibiotic with IV clot-busting for acute stroke
This trial tests whether adding the antibiotic levofloxacin to standard IV clot-busting treatment is safe and improves outcomes after an acute ischemic stroke. It may help by reducing complications related to infection or inflammation, but you must meet specific heart, liver, kidney, and medication-safety rules.
Changchun, JilinAges 18–75 - NCT06124248Recruiting
RISE program to help stroke survivors sit less and move more
This study tests if a program called RISE can help people who have had a stroke reduce the amount of time they spend sitting. The goal is to see if it helps improve recovery and daily life after returning home from the hospital.
's-Hertogenbosch, North BrabantAges 18 years+ - NCT06618248Recruiting
Sirolimus balloon for heart artery blockages at branches
This study tests a balloon coated with sirolimus (a medicine to prevent re-narrowing) to treat blockages in branch arteries of the heart. It may help patients who need a stent in the main artery but have a side branch that can be treated with this balloon instead of a stent.
Beijing, Beijing MunicipalityAges 18–85 - NCT07738978Recruiting
Movement and health study for paralysis
This study is looking at ways to improve movement and health for people with paralysis from conditions like spinal cord injury, stroke, traumatic brain injury, or multiple sclerosis. It involves exercises and may include electrical stimulation to help your leg and trunk muscles work better.
Cleveland, OhioAges 18 years+ - NCT07735221Recruiting
Peanuts for stress and heart health
This trial tests whether eating peanuts every day can reduce stress, improve immune function, and lower inflammation in people who feel stressed. If you are stressed and generally healthy, you may qualify.
Davis, CaliforniaAges 18–65 - NCT07734506Recruiting
Muscle thickness and sarcopenia in stroke survivors
This study looks at how thigh muscle thickness measured by ultrasound relates to muscle weakness and fear of movement in people who have had a stroke. It may help find better ways to assess muscle health and recovery.
Istanbul, IstanbulAges 40–80 - NCT07736885Recruiting
Hand stimulation for thinking problems after stroke
This study tests a gentle, painless electrical stimulation on specific points on the hands to see if it helps improve thinking and memory after a stroke. It is for people who have had a stroke in the last 2 weeks to 6 months and are noticing some cognitive changes.
Tianjin, Tianjin MunicipalityAges 35–80 - NCT07737236Recruiting
Ruscus study for symptom relief in chronic vein problems
This study tests a natural plant extract called Ruscus to see if it helps control symptoms of chronic venous insufficiency, a condition where leg veins have trouble moving blood back to the heart. It is for people who are already starting this treatment as part of their regular care.
Ankara, AnkaraAges 18–75 - NCT07735156Recruiting
Treating Pelvic Pain with Vein Blockage
This study tests a minimally invasive procedure that blocks abnormal veins in the pelvis to relieve long-term pelvic pain. It may help women with pelvic congestion syndrome.
Sohag, Sohag GovernorateAges 17–55
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,610 recruiting cardiology studies from the U.S. registry right now, out of 14,650 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.