Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT07361055Enrolling by invitation
Heart ablation study using no X-ray
This trial tests a new way to treat a fast heart rhythm called PSVT using a procedure that avoids X-ray radiation. It aims to see if this approach is safer and works well for patients who need this treatment.
TaipeiAges 18 years+ - NCT07360561Enrolling by invitation
Mobile health game to boost physical activity for heart health
This study uses a smartphone app with game-like features to help you become more active over several months. Researchers want to see if this approach can improve heart health and lower risk factors for heart disease in university students and employees like you.
Bursa, NİLÜFERAges 18–65 - NCT07358793Recruiting
Simulation training for emergency teams
This study compares two ways of training emergency teams to handle adult medical emergencies (not from injury). It looks at how well teams work together using a standard approach called A-C-L-S.
Douliu, YunlinAges 18 years+ - NCT05307263Recruiting
Atherectomy plus drug balloon versus drug balloon alone
This study compares two ways to treat complex blockages in the thigh/knee artery: using atherectomy followed by a medicated balloon versus using a medicated balloon by itself. It may help your care team learn which approach works best to open the artery and improve leg symptoms.
SeoulAges 19–85 - NCT07356635Recruiting
Study on how grieving affects the heart
This study looks at how the grief from losing a loved one may affect your heart and blood vessels. It aims to understand the physical changes that happen during the grieving process.
Tampa, FloridaAges 18 years+ - NCT06555211Recruiting
Exercise effects on heart and kidneys in healthy people
This study looks at how isometric exercise (like planks or wall sits) affects your heart and kidneys, using advanced scans (PET/CT and MRI). It's for healthy people to understand the normal effects of exercise on these organs.
Copenhagen, Capital RegionAges 18–60 - NCT05300971Recruiting
Heat therapy to lower blood pressure in midlife and older adults
This study tests whether regularly using passive heat can lower your systolic blood pressure (the top number) and improve how your blood vessels work. If you’re eligible, you may be randomly assigned to try the heat therapy as a 6-month program.
Boulder, ColoradoAges 40 years+ - NCT07415109Recruiting
Personalized health messages to lower cholesterol
This study tests whether health messages tailored to your personality can help you lower your LDL (bad) cholesterol levels. It is for participants of the RESET study who are at least 21 years old and can communicate in English.
SingaporeAges 21–65 - NCT07351838Recruiting
Heart MRI for risk screening in early cardiomyopathy
This study uses heart MRI to find people with early signs of heart muscle disease who still have normal-sized heart chambers. It aims to better predict who is at risk so they can get earlier care.
BeijingAges 16 years+ - NCT07352891Recruiting
Digital remote management vs. usual care for heart failure
This trial tests whether using a remote monitoring platform to help manage medications improves outcomes in people with heart failure and reduced pumping function. It compares this approach to standard follow-up care.
BeijingAges 18 years+ - NCT04884802Recruiting
GUARDIAN Trial for safer blood pressure during major surgery
This trial studies a way of managing blood pressure during major surgery to help reduce complications. It is for older adults and others at higher risk who will be closely monitored in the hospital.
Omaha, NebraskaAges 45 years+ - NCT05802849RecruitingPhase 4
Oral acetazolamide for worsening heart failure
This trial tests whether taking acetazolamide by mouth can help prevent or improve worsening (decompensation) of heart failure after you needed IV water pills (diuretics). It’s mainly for adults with a recent heart-failure flare and specific heart/lab signs, while carefully excluding certain low blood pressure, kidney issues, and electrolyte or acid–base problems.
SamaraAges 18 years+ - NCT07349498Recruiting
Heart health after stem cell transplant
This study follows patients who have had a stem cell transplant to see how their heart and blood vessels are doing over time. It helps doctors learn about long-term heart risks after transplant.
Beijing, Beijing MunicipalityAges Any age - NCT06373497RecruitingEarly Phase 1
Heart artery health after chest radiation using PET scan
This study looks at how radiation therapy to the chest affects the arteries in your heart. It uses a special PET scan (with a safe radioactive tracer) to check for early signs of inflammation or plaque buildup, which can help doctors find ways to protect your heart during cancer treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07345156Recruiting
Congestion and lactate at discharge in heart failure
This trial studies a simple test (lung ultrasound and a blood test for lactate) done right before you leave the hospital for heart failure. It aims to see if these tests help doctors know how well you are recovering and if you might need extra care after discharge.
Monastir, Monastir GovernorateAges 18 years+ - NCT07343843Recruiting
Virtual reality vs sedative for anxiety during C-section
This study compares two ways to reduce anxiety and stress during a planned C-section: using a virtual reality headset versus a sedative medicine given through an IV. It aims to see which approach helps mothers feel calmer and supports better outcomes for both mom and baby.
Banhā, BenhaAges 18 years+ - NCT07393165Recruiting
Thyroid hormone therapy for children with mild thyroid issues
This trial tests whether a thyroid hormone medication (levothyroxine) can improve heart function in children who have slightly high TSH levels but normal thyroid hormones. It may help children aged 4 to 15 with subclinical hypothyroidism.
Tanta, El-GharbiaAges 4–15 - NCT06090253Recruiting
Sport exercise program for healthy aging over 60
This trial tests a program that uses sports and exercise to help people over 60 stay healthy and active. It looks at both how well the program works and how easy it is to put into practice.
Hong KongAges 60 years+ - NCT07338370Recruiting
PGE2 levels and heart duct closure in preterm babies
This trial measures a substance called prostaglandin E2 (PGE2) in preterm babies to see if it can predict whether a heart blood vessel (ductus arteriosus) will close on its own or need treatment. This could help doctors decide when to use medication to close the vessel.
Cairo, AbbasiaAges 1 day–1 week - NCT05699200Recruiting
Study of nerves involved in spontaneous coronary artery dissection
This study looks at how the body’s automatic “fight-or-flight” nerve system may relate to spontaneous coronary artery dissection (SCAD). If you have a SCAD history, your results may help researchers understand the condition better; if you’re a healthy control, your data are compared to SCAD patients.
Rochester, MinnesotaAges 18 years+ - NCT05850962Recruiting
Personalized blood pressure targets for ICU shock care
This study compares individualized blood pressure goals versus the usual (standard) targets for adults in the ICU with shock. The aim is to see whether tailored blood pressure treatment can improve outcomes by better matching each person’s needs.
Newcastle, New South WalesAges 40 years+ - NCT07335770Enrolling by invitation
Heart MRI for diagnosing and managing heart masses
This trial uses cardiac MRI to better understand heart masses (tumors or clots) and guide treatment decisions. It may help determine what the mass is and how it affects your health.
Ages Any age - NCT06487052Recruiting
Catheter-based clot-dissolving drug for intermediate-high risk pulmonary embolism
This trial tests whether a standard procedure using a catheter to deliver clot-dissolving medicine directly into the lung artery works well for people with a serious but not immediately life-threatening blood clot in the lungs (pulmonary embolism). It aims to improve heart function and reduce long-term complications.
Saint PetersburgAges 18 years+ - NCT06543394Enrolling by invitation
Helping patients take blood pressure medication regularly
This trial tests whether a behavioral science approach can help people with high blood pressure take their medication as prescribed. If you have trouble remembering or sticking with your blood pressure pills, this study may help you find better ways to stay on track.
New York, New YorkAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.