Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT06963567Recruiting
Heart blood clot registry
This study keeps track of people who have or are at risk for a blood clot in the heart's main pumping chamber (left ventricle). It helps doctors learn more about how to care for these patients.
Cambridge, CambridgeshireAges 18 years+ - NCT07265453Recruiting
Heart health study for Ugandan teens and families
This study looks at whether a family-based program can improve heart health for adolescents in Uganda. You and your family would work together on healthy habits over the next year.
JinjaAges 10–19 - NCT05965258Recruiting
Classify mitral regurgitation using heart scans
This study uses heart imaging to better understand different types of mitral valve leak (mitral regurgitation) and how it relates to heart pumping function. Results may help doctors match people to the most appropriate care based on scan “patterns.”
Cleveland, OhioAges 18 years+ - NCT07265466RecruitingPhase 1
Safety study of JP-1366 with common heart and blood medications
This trial tests how a new drug, JP-1366, interacts with several common heart and blood medications (clopidogrel, aspirin, atorvastatin, and apixaban) in healthy volunteers. It aims to see if the combination is safe and how the drugs affect each other in the body.
Seongnam-si, Gyeonggi-doAges 19–64 - NCT06938347RecruitingPhase 3
New contrast agent for heart ultrasound to detect shunts
This trial tests a new contrast agent (ASI-02) compared to a standard saline solution for people who need a heart ultrasound to detect a right-to-left shunt. It may help provide clearer images so doctors can make a better diagnosis.
Chicago, IllinoisAges 18 years+ - NCT07264400Recruiting
Pregnancy exercise and baby heart health
This trial looks at how a mother's physical activity during pregnancy might affect her newborn's heart function. It is part of a larger study called PregMouv, and researchers want to see if staying active leads to better heart rate variability in babies.
Clermont-FerrandAges 1 day–3 days - NCT05062239Recruiting
Statin use after valve surgery to prevent heart rhythm trouble
This study looks at whether taking statin medicines around the time of surgical aortic valve replacement can lower the chance of a common post-surgery heart rhythm problem called atrial fibrillation. It also compares statin-related factors in people who are at the time of surgery in normal rhythm and not on strong rhythm-stabilizing medicines.
OdenseAges 60–95 - NCT06516822Recruiting
Comparing two ablation methods for long-standing atrial fibrillation
This study tests whether adding extra scar lines (linear ablation) to the standard pulmonary vein isolation (CPVI) is better than CPVI alone for people with long-standing persistent AF that has lasted 1 to 3 years. The goal is to see which approach reduces AF better.
Beijing, Beijing MunicipalityAges 18–75 - NCT05400317RecruitingPhase 3
Check AD-218 for fibromyalgia symptoms and safety
This phase 3 study tests whether AD-218 works and is safe for people with fibromyalgia. It may help by improving symptoms, but it also carefully monitors side effects.
Daegu, Nam-guAges 19 years+ - NCT06822712Recruiting
Sirolimus-coated balloon for heart artery branch blockages
This trial tests a new balloon coated with sirolimus (a drug that helps prevent re-blockage) for treating blocked arteries at branch points (bifurcations) in the heart. If you have a blocked artery at a branch point, this study may offer a way to treat the side branch without placing a stent there.
Lanzhou, GansuAges 18–80 - NCT07010354Recruiting
BeFlow Stent Study for Iliac Artery Blockages
This study is testing a new stent called BeFlow to see how well it works and how safe it is for people with blocked or narrowed iliac arteries. The stent is placed permanently to keep the artery open.
AalstAges 18 years+ - NCT06518915Recruiting
Baroloop trial for stubborn high blood pressure
This trial tests a device that helps control blood pressure by gently stimulating a nerve in your neck. It may help if your blood pressure stays high even while taking three different medications.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT07254078Recruiting
Registry for chronic thromboembolic pulmonary hypertension patients
This study is a registry that collects information about people with chronic thromboembolic pulmonary hypertension (CTEPH). It helps doctors learn more about how this condition affects patients over time and how it is treated.
MoscowAges 18 years+ - NCT07738419Recruiting
AI Heart Ultrasound Measurement Accuracy Study
This study tests an artificial intelligence program designed to automatically take measurements from standard heart ultrasound images. It aims to see if the AI works as well as expert doctors.
Milan, LombardyAges 18 years+ - NCT06680271Enrolling by invitation
Exercise program from home for older adults with heart or lung disease
This trial tests whether a home-based exercise program, guided remotely by a therapist, can help older adults with conditions like COPD, asthma, heart failure, or metabolic syndrome. The goal is to improve their health and quality of life without needing to go to a clinic.
Envigado, AntioquiaAges 60–100 - NCT07736222Recruiting
Does chewing affect artery stiffness in healthy adults?
This study looks at how your oral health and chewing habits might relate to your artery stiffness—a measure of heart health. Researchers will test participants' chewing ability and check their arteries using simple, non-invasive methods.
Innsbruck, TyrolAges 18 years+ - NCT07249671Recruiting
Rope skipping for kids' heart and lung fitness
This study tests if rope skipping can improve heart and lung fitness in healthy children ages 6 to 12. It may help kids get more active and build endurance.
Chak Four Hundred Fifty-four, Punjab ProvinceAges 6–12 - NCT07325942Recruiting
Low vs high volume high-intensity interval training for heart failure
This study compares two different types of high-intensity interval exercise programs (one shorter, one longer) in people with chronic heart failure. It aims to see which program improves heart health and daily function more.
Cairo, Giza GovernorateAges 18 years+ - NCT06826534Recruiting
At-home heart rehab for teens with heart failure risk
This study tests if a home-based exercise program using a Fitbit can help teens who had chemotherapy improve their heart and lung fitness. You would exercise at home, track your activity, and have monthly virtual check-ins for 6 months.
Los Angeles, CaliforniaAges birth–21 years - NCT07247474Recruiting
Using electrical impedance tomography for heart and lung imaging
This trial uses a safe, non-invasive technique called EIT to monitor heart and lung function in children and young adults with certain heart or lung conditions, compared with healthy volunteers. It may help doctors better understand and manage these conditions.
Aurora, ColoradoAges 2 weeks–25 years - NCT07658651Recruiting
Plug for type B aortic dissection repair
This trial tests a special plug (WeFlow-EndoSeal) placed into the false channel of a type B aortic dissection to help seal it. It is for people who are already getting a stent-graft and aims to improve the repair.
Beijing, Beijing MunicipalityAges 18–80 - NCT06464731Recruiting
Clot removal for mild stroke due to large artery blockage
This trial tests whether removing a blood clot from a large brain artery (using a catheter through the groin) can help people with mild stroke symptoms. It is for patients whose stroke started within the last 24 hours and who have a blockage in the front part of the brain's blood supply.
Zhangzhou, FujianAges 18–80 - NCT07341932Recruiting
Heart mapping test for stable coronary artery disease treatment
This trial tests whether a non-invasive heart mapping technique can guide treatment for stable coronary artery disease, potentially avoiding more expensive or invasive tests. You may join if you have stable angina and a blockage of 50-90% in a major heart artery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06829160Recruiting
Heart rehab app for patients with chest pain and clear arteries
This trial tests a smartphone-based cardiac rehabilitation program for people with INOCA, a condition where you have chest pain or other signs of heart trouble despite having no major blockages in your heart arteries. The goal is to see if using the app can improve your heart health and quality of life.
New York, New YorkAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.