Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,610 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3437
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke796
- Heart Failure534
- Hypertension389
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease84
- Peripheral Arterial Disease80
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California451
- Alabama195
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois111
Recruiting studies9,610 total
- NCT07728643Recruiting
Blood vessel particles in children with new high blood pressure
This study looks at tiny particles in the blood (called extracellular vesicles) that may signal early blood vessel changes in children with new high blood pressure. If your child is between 6 and 17, has just been diagnosed with high blood pressure and hasn't started treatment, and is otherwise healthy, this trial may help doctors better understand how high blood pressure affects kids.
OsijekAges 6–17 - NCT07732244Recruiting
Testing a wireless brain oxygen monitor in the NICU
This study is testing a new wireless device that monitors oxygen levels in the brain. It is for babies already using a similar wired monitor, to see if the wireless version works just as well.
Montreal, QuebecAges Any age - NCT07726251Recruiting
Heart changes during jaw surgery
This study looks at how your heart and blood pressure change during a type of jaw surgery called bimaxillary orthognathic surgery. It will help doctors understand a reflex that can affect your heart rate during the procedure.
Kirikkale, KırıkkaleAges 18–40 - NCT07725471Recruiting
Comparing breathing and neck release in stroke recovery
This study compares two gentle therapy techniques—special breathing exercises and a hands-on release at the base of the skull—to see which helps stroke survivors with one-sided weakness regain movement and breathing. It may be a good fit if you're still recovering from a first stroke months ago and don't have major heart or lung problems.
AfyonkarahisarAges 18–84 - NCT07725250Recruiting
AI-guided blood pressure trial for stage I-II hypertension
This study tests whether combining artificial intelligence with personalized medicine can help lower blood pressure in people with stage I or II hypertension (140/90 or higher). If you have high blood pressure and can walk without help, this trial may be for you.
La Jolla, CaliforniaAges 18 years+ - NCT07724730Recruiting
Moving with and without music after a stroke
This study compares two types of movement practice for people recovering from a recent stroke. One group will do everyday tasks like walking and reaching, and the other will do the same movements but with a rhythmic beat to help with timing and coordination.
Daska KalanAges 40–60 - NCT07724262Recruiting
Testing the Argos System to measure heart blood flow
This trial is testing a new system called Argos to see if it can measure how much blood your heart pumps more easily than current methods. It is for patients already in the ICU who need a quick change in fluids or blood pressure medicine.
Le Kremlin-BicêtreAges 18 years+ - NCT07724899Recruiting
A new ablation treatment for atrial fibrillation
This study tests a new type of ablation (pulsed field ablation) for people with atrial fibrillation who haven't gotten enough relief from medication alone. It aims to see if isolating the superior vena cava along with the pulmonary veins is safe and effective.
Chengdu, SichuanAges 18 years+ - NCT07724184Recruiting
Treating calcified heart arteries with a stent
This trial tests a way to treat hardened, calcified heart artery blockages using a stent. It may help people who have moderate blockages that haven't been treated before.
AalborgAges 18–90 - NCT07731087Recruiting
Stem cell secretion therapy for thinking recovery after stroke
This study tests whether a therapy made from stem cell secretions can help improve memory and thinking after an ischemic stroke. It is for people who had a clot-related stroke in the past 3 months and now have mild to moderate cognitive issues.
Makassar, South SulawesiAges 40–75 - NCT07725887Recruiting
Structured physical therapy for high-risk heart bypass patients
This trial tests a structured physical therapy program for patients at high risk who are getting heart bypass surgery. The therapy is done in the hospital before and after surgery to help you recover better.
Istanbul, EyupsultanAges 18–90 - NCT03781401Recruiting
Blood pressure monitoring at local pharmacies
This trial studies using a telemedicine system to check blood pressure in community pharmacies. It may help people with known high blood pressure (treated or untreated) get safer, more convenient monitoring.
Solbiate ArnoAges Any age - NCT05305911RecruitingPhase 2
SGLT2 drug after first heart attack to reduce heart damage
This Phase 2 trial tests whether an SGLT2 medicine started after a first STEMI heart attack can reduce ongoing heart muscle injury and scarring. It may help people who, based on heart imaging, have larger infarcts and ongoing microvascular damage.
Minneapolis, MinnesotaAges 18–75 - NCT06629116Recruiting
Albumin treatment for large strokes after thrombectomy
This trial tests if giving a protein called albumin after a large stroke can improve recovery. Albumin may help reduce brain swelling and damage. You may qualify if you had a large stroke in the front part of the brain, got a clot-removal procedure, and meet certain age and health criteria.
Zhangzhou, FujianAges 18–80 - NCT06630923RecruitingPhase 3
Preventing kidney worsening with IV albumin in heart failure
This trial tests if giving a medicine called albumin through a vein can help prevent kidney function from getting worse in people hospitalized with worsening heart failure and liver problems. It may be an option if other treatments haven't worked.
Alexandroupoli, EvrosAges 18–95 - NCT06383975Recruiting
Two new treatments for AF that returned after first procedure
This trial tests two new treatments for persistent atrial fibrillation that came back after an initial procedure. One uses a targeted chemical injection, the other uses a special energy field to re-isolate the veins involved.
BrugesAges 18 years+ - NCT05015452Recruiting
Registry for people who get TAVI
This is a patient registry that collects information from people who receive TAVI, a procedure used to treat certain heart valve problems. It may help doctors better understand who benefits and how patients do over time.
LeipzigAges 18 years+ - NCT04844944Recruiting
Heart registry for adults with heart failure, CAD, or atrial fibrillation
This is a hospital-based study that collects standardized information about adults with specific heart conditions—heart failure, coronary artery disease, or atrial fibrillation. It may help doctors and researchers better understand these diseases and improve future care.
BerlinAges 18 years+ - NCT05961202RecruitingPhase 2/Phase 3
Hydroxychloroquine for inflammatory heart muscle weakness
This trial tests hydroxychloroquine to see if it improves symptoms and heart function in people with inflammatory cardiomyopathy (inflammation of the heart muscle). It’s mainly for adults with a specific type of past myocarditis and ongoing heart failure despite standard treatments.
Wuhan, HubeiAges 18–80 - NCT06396767Recruiting
Breathing test before heart surgery to predict lung problems
This study uses a simple breathing test before scheduled heart surgery to see if it can help predict breathing or lung complications after the operation. The results may help doctors identify patients who need extra support during recovery.
London, OntarioAges 19–99 - NCT06634121Recruiting
Comparing MitraClip and PASCAL for mitral valve repair
This trial compares two devices (MitraClip and PASCAL) for repairing a leaky mitral valve (mitral regurgitation). The goal is to see which device works better in a wide range of patients who need this type of repair.
Munich, BavariaAges 18 years+ - NCT06633809Recruiting
Treating minor stroke with large artery blockage
This study tests whether a specific treatment (likely endovascular therapy) helps people who have a minor stroke caused by a blockage in a large brain artery. If you are eligible, you may receive this treatment within 24 hours of your stroke to try to improve your recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT07721025RecruitingPhase 2
Gene therapy trial for Friedreich ataxia heart disease
This trial tests a one-time gene therapy called LX2006 for heart problems caused by Friedreich ataxia. The goal is to see if it can improve heart function and structure.
Tampa, FloridaAges 6 years+ - NCT07715630RecruitingPhase 1
PICX CAR-T therapy for relapsed or hard-to-treat multiple myeloma
This trial tests a new treatment called PICX CAR-T, a type of immune cell therapy, for multiple myeloma that has come back or not responded well to at least two prior treatments. It aims to see if this therapy can help control the disease.
Kunming, YunnanAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,610 recruiting cardiology studies from the U.S. registry right now, out of 14,650 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.