Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT07287345RecruitingPhase 4
Colchicine’s effect on inflammation after heart bypass surgery
This trial tests whether the drug colchicine can reduce inflammation after planned coronary artery bypass graft (CABG) surgery. It may help patients recover better by lowering inflammatory markers.
Lexington, KentuckyAges 18–99 - NCT07390214Recruiting
Comparing two catheters for repeat atrial fibrillation ablation
This study compares two types of catheters (AFFERA vs. standard contact-force guided) for a repeat ablation procedure in people whose atrial fibrillation or related symptoms returned after a first ablation. It aims to find which catheter works best for a second treatment.
Frankfurt am Main, HesseAges 18–85 - NCT06968858RecruitingPhase 1/Phase 2
Testing a new device to find blocked heart stents
This trial tests a new, non-invasive device that uses microwaves to detect if a heart stent is blocked. If you have a stent and are scheduled for a heart catheterization, this study may help see if the device works as well as the standard procedure.
Badalona, CataloniaAges 18 years+ - NCT07001332Recruiting
High-risk heart stent procedure study
This study tests a new device to help people with high-risk blockages in their heart arteries during a stent procedure. It compares the new device to standard treatment to see if it is safe and effective.
Phoenix, ArizonaAges 18–88 - NCT07286890Recruiting
Beating Heart Bypass Surgery Study with Getinge Devices
This study follows patients who have a type of heart bypass surgery called 'beating heart' CABG, where a special Getinge device is used to keep the heart pumping during the operation. It helps doctors learn more about how well these devices work in real-world use.
Stockton, CaliforniaAges 22 years+ - NCT07282418RecruitingPhase 1/Phase 2
Study on recreation and health habits
This trial explores how recreational activities affect your health and well-being. You'll use your phone to answer quick surveys and may be asked to try new recreational activities.
Chicago, IllinoisAges 18 years+ - NCT06131112Recruiting
PET scan for heart inflammation in sarcoidosis
This study tests if a special PET scan with 64Cu-DOTATATE can detect inflammation in the heart caused by sarcoidosis. It may help diagnose heart sarcoidosis more accurately in people with symptoms or known disease.
CopenhagenAges 18 years+ - NCT07381816Enrolling by invitation
Study of gut blood flow in people with post-meal low blood pressure
This study uses MRI to measure blood flow in the gut when you eat, to understand why some people get dizzy or lightheaded after meals. It compares people with postprandial hypotension to healthy volunteers.
Glostrup MunicipalityAges 18–90 - NCT04477629RecruitingPhase 2
Belatacept for first-time heart transplant recipients
This trial studies whether belatacept, an anti-rejection medicine given by IV, can work for people receiving their first heart transplant. It aims to see if it prevents rejection safely for patients and whether it fits better than standard approaches for certain candidates.
New York, New YorkAges 18–75 - NCT05575661Recruiting
Study links low blood pressure after meals and after anesthesia
This study looks at whether people who have low blood pressure after eating are also more likely to have low blood pressure after starting general anesthesia. It may help doctors better predict and manage blood pressure drops during non-heart surgeries in older adults.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06965257Recruiting
Blood pressure monitoring study for carotid surgery
This study tests a non-invasive blood pressure monitor during carotid artery surgery to see if it can replace the standard arterial catheter. It may help patients by reducing the need for a tube placed in an artery.
Créteil, FranceAges 18 years+ - NCT05115890Recruiting
Testing blood-flow control in heart failure with preserved pumping
This study looks at how well blood flow is regulated in people with HFpEF, a type of heart failure where the heart squeezes normally but doesn’t fill properly. It may help researchers understand the cause of symptoms and how to improve treatment strategies.
Salt Lake City, UtahAges 18 years+ - NCT04458532Recruiting
Exercise program to boost heart health after early breast cancer
This trial studies whether a structured exercise program can improve cardiovascular (heart and blood vessel) health in post-menopausal women after early-stage breast cancer treatment. It specifically targets women who have trouble with exercise and have completed cancer treatment within the last 1 to 5 years.
Hartford, ConnecticutAges 21–80 - NCT07692425Recruiting
Neck vein test to predict blood pressure drop during surgery
This study tests whether checking how much the jugular vein (a vein in the neck) collapses can help predict drops in blood pressure during surgery. It's for older adults having laparoscopic colon or rectal surgery.
CairoAges 60 years+ - NCT07277114Recruiting
Drug balloon vs stent for hardened arteries after special preparation
This trial compares two treatments for severely calcified coronary arteries: a drug-coated balloon (DCB) and a drug-eluting stent (DES). It is for people who have already had a procedure to crack or soften the calcium (like rotational atherectomy), and whose blood flow looks good afterward.
ShanghaiAges 18 years+ - NCT06811831RecruitingEarly Phase 1
Mactientan for chest pain from small heart artery problems
This trial tests if mactientan, a blood vessel relaxer, can improve chest pain in people with coronary microvascular angina—where small heart arteries don't work right even though larger ones are clear. It aims to help those with ongoing angina symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT06490731RecruitingPhase 1/Phase 2
Comparing two sedatives for ICU recovery after bowel surgery
This trial tests whether dexmedetomidine or ketamine is better at reducing inflammation and keeping blood pressure stable in patients recovering from emergency abdominal surgery. It may help doctors choose the best sedation for you after surgery.
AsyutAges 18–70 - NCT06813820Recruiting
Less invasive heart reshaping for heart failure
This trial tests a less invasive procedure to reshape the heart in people with heart failure due to a scar or aneurysm. It aims to improve heart function and symptoms.
Phoenix, ArizonaAges 18 years+ - NCT05747404Recruiting
3D heart ultrasound study for certain right-heart problems
This study uses a special 3D heart ultrasound to measure how well the tricuspid valve and right side of the heart are working. It may help improve how these conditions are evaluated and followed over time.
MilanAges 18 years+ - NCT07177391Recruiting
Quick heart ultrasound test in the ICU
This trial tests a new way to measure how much blood your heart pumps using a simple ultrasound from under your ribs. It may help doctors monitor your condition without more invasive tests.
RouenAges 18 years+ - NCT07179029Recruiting
Can anesthesia affect the heart during non-cardiac surgery?
This study looks at whether anesthesia can cause heart damage during non-cardiac surgeries. If you have certain health risks, participating may help doctors learn how to better protect your heart.
TübingenAges 40–80 - NCT02168088Recruiting
Study tissues to understand causes of sudden deaths
This trial collects and studies medical information and tissue from people who died suddenly with no clear cause, aiming to better identify hidden heart- and clot-related causes. It may help researchers improve how sudden deaths are investigated in the future.
La Jolla, CaliforniaAges Up to 45 years - NCT07272798Recruiting
Heart confidence after pulmonary hypertension surgery
This study looks at how confident patients feel about managing their heart health after surgery for chronic thromboembolic pulmonary hypertension. It may help doctors understand how to better support recovery.
Damascus, Rif-dimashq GovernorateAges Any age - NCT04733404Recruiting
Dragonfly device study for functional mitral valve leakage
This trial tests a catheter-based procedure (putting a small device through blood vessels) to repair a leaking mitral valve caused by heart muscle problems. It aims to reduce symptoms and improve heart function and safety in people who are still having heart failure symptoms despite standard treatment.
Hangzhou, ZhejiangAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.