Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,610 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3437
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke796
- Heart Failure534
- Hypertension389
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease84
- Peripheral Arterial Disease80
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California451
- Alabama195
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois111
Recruiting studies9,610 total
- NCT06635187Recruiting
Oral-motor assessment and rehab app study
This study tests a mobile app that helps assess and train the muscles used for speaking and swallowing. It is for Cantonese-speaking adults who are either healthy or have had a stroke.
Hong Kong, Hong KongAges 20–85 - NCT04344912Recruiting
Study of COVID-19 effects on heart emergency care
This study looks at how the COVID-19 outbreak affected care for people admitted to the cardiac intensive care unit. It may help hospitals improve how they plan and respond during major outbreaks.
ParisAges 18 years+ - NCT05586282Recruiting
Study proteins that may worsen fluid leaks in shock
This trial studies specific body proteins to understand why fluid can leak from blood vessels during dangerous shock after infection or heart problems. If you (or your representative) qualify, your team will collect information and possibly samples to see whether these proteins relate to recovery and treatment response.
ParisAges 18 years+ - NCT05708859RecruitingPhase 4
Tirzepatide to slow plaque buildup in coronary arteries
This trial studies tirzepatide to see if it can slow the progression of coronary artery plaque in people with type 2 diabetes. It uses special heart CT scans to track changes over time.
Torrance, CaliforniaAges 40–80 - NCT06635603Recruiting
Atmospheric pressure and hypertensive crisis study
This study looks at whether changes in atmospheric pressure (the weight of the air) are linked to very high blood pressure emergencies. You may be able to join if you come to the emergency room with a hypertensive crisis but without organ damage.
AnkaraAges 18 years+ - NCT04331249Recruiting
Monitoring heart device during and around your procedure
This trial looks at how to manage and check implanted heart devices (pacemakers/defibrillators) during and around a planned procedure. It may help teams improve safety and decision-making during surgery or catheter procedures.
Fürth, BavariaAges 18 years+ - NCT04416958Recruiting
Pacemaker or defibrillator pacing strategy to reduce heart timing issues
This study looks at a pacing approach for people with a pacemaker or ICD (defibrillator) to help prevent the heartbeats from becoming out of sync. It may be useful if your implant team is trying to reduce pacing-related “timing” problems in the heart.
Fürth, BavariaAges 18 years+ - NCT04912518Recruiting
Dexmedetomidine for heart protection after a specific heart attack
This study tests whether dexmedetomidine can protect the heart in people who are having a specific type of heart attack (anterior STEMI) when treated within 6 hours of symptom start. You may be considered if your diagnosis and vital signs fit the study safety rules, and if you can take part in follow-up.
Hefei, AnhuiAges 18–75 - NCT05438121Recruiting
Tests a drug-coated balloon to stabilize clogged heart arteries
This trial studies whether a drug-coated balloon can better treat new, narrowed spots in multiple coronary arteries and “stabilize” the plaque. It may help improve blood flow after a procedure called balloon angioplasty for selected patients.
Ansan-si, Gyeonggi-doAges 18–85 - NCT05299424RecruitingPhase 1/Phase 2
CM336 for multiple myeloma after prior treatments
This trial tests CM336, a new medicine, in people with multiple myeloma that has returned (relapsed) or not responded (refractory) to standard treatments. It may help by trying a different approach when other key medicines have already been tried.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05102448RecruitingPhase 4
Tofacitinib vs methotrexate for active Takayasu’s arteritis
This trial compares two medicines—tofacitinib and methotrexate—to see which works better for controlling active Takayasu’s arteritis. It also looks at safety in people with this condition who need treatment right now.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06350110RecruitingPhase 1/Phase 2
CAR T cells for lupus
This trial tests a new type of CAR T cell therapy for people with active lupus that has not responded to other treatments. It uses specially engineered cells to target and eliminate certain immune cells that are causing the disease, with the goal of reducing symptoms and preventing flare-ups.
Beijing, Beijing MunicipalityAges 18–90 - NCT06109324Recruiting
Robotic exercises for sensory and cognitive recovery after stroke
This study tests whether robotic exercises can improve sensory and cognitive abilities in people who recently had a stroke. It may help you regain better function in your daily activities.
FlorenceAges 18–85 - NCT06211868Recruiting
Early heart disease risk study for adults 40-70
This study looks at whether changing your immune system, fats, and metabolism can lower your risk of early heart disease. It is for people with an intermediate to high risk score but who have not yet had a heart attack or stroke.
SingaporeAges 40–70 - NCT06637657Recruiting
Optimizing long-term heart disease prevention
This trial tests different ways to manage and reduce the risk of future heart problems in people who have already had a heart attack or a procedure to open blocked heart arteries. The goal is to find the best long-term treatment plan to keep you healthy.
AmsterdamAges 18 years+ - NCT06631534RecruitingPhase 4
Testing dexmedetomidine for kids having heart defect closure
This trial tests adding a sedative medicine called dexmedetomidine to standard anesthesia for children aged 3 to 12 who are having a procedure to close a hole in their heart (atrial septal defect). The goal is to see if it helps them recover more smoothly.
Alexandria, Alexandria GovernorateAges 3–12 - NCT07714252Enrolling by invitation
Virtual palliative care team for veterans with heart or lung disease
This study tests a virtual team of nurses and social workers who provide palliative care to veterans with heart failure, COPD, or interstitial lung disease. The goal is to improve quality of life by offering extra support at home.
Phoenix, ArizonaAges 18 years+ - NCT07709364Recruiting
Heart rate feedback to help nurses make better decisions
This trial tests whether showing nurses their own heart rate data can help them make better decisions during patient care. It aims to improve recovery support for patients.
Cambridge, CambridgeshireAges 21 years+ - NCT06642623RecruitingPhase 4
Study on heart and kidney health in type 2 diabetes
This trial tests enavogliflozin (a newer SGLT2 inhibitor) compared to older drugs (dapagliflozin or empagliflozin) to see how well it protects the heart and kidneys in people with type 2 diabetes.
SeoulAges 19 years+ - NCT06639737Recruiting
Optimizing blood volume before surgery using heart ultrasound
This trial tests whether using a heart ultrasound before surgery can help doctors better manage your blood volume. If you are having surgery under general anesthesia and have a higher risk of heart problems, this study may help improve your safety.
Caen, NormandyAges 18–99 - NCT07712445Recruiting
Testing a clot-busting drug coated with platelet membranes
This study tests a new way to deliver a clot-dissolving drug called tenecteplase. The drug is coated with platelet membranes to target blood clots in arteries. It may offer a safer, more effective treatment for heart attack patients and is also enrolling healthy volunteers for comparison.
Nanjing, JiangsuAges 18–75 - NCT07709208Recruiting
Mitral valve repair for leak that worsens with exercise
This trial tests a procedure to fix a leaky mitral valve that only becomes severe during exercise. It may help people with symptoms like shortness of breath or fatigue who haven't responded to standard heart medications.
DüsseldorfAges 18 years+ - NCT07706816Recruiting
Remote stress recovery program for young heart attack survivors
This study tests a remote program to help people under 55 recover from the stress of a heart attack. It aims to see if the program is practical and helpful for reducing distress after a heart attack.
UppsalaAges 18–55 - NCT07711821Recruiting
Heart failure screening in primary care for older adults
This trial is testing a simple screening tool to find early signs of heart failure in people aged 50 or older, especially those with risk factors like diabetes or high blood pressure. If you're at risk, this could help catch heart problems sooner.
AmadoraAges 49 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,610 recruiting cardiology studies from the U.S. registry right now, out of 14,650 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.