Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,616 recruiting studies in this area right now.
By phase
- Not applicable5,344
- Phase 2606
- Phase 1557
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Thyroid Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Johns Hopkins University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas159
- Massachusetts150
- New York144
- Colorado115
- Pennsylvania113
Recruiting studies7,616 total
- NCT07245771RecruitingPhase 1/Phase 2
Weight loss study testing a new drug alone or with tirzepatide
This trial tests an experimental drug called RN3161 to see if it helps with weight loss in people with overweight or obesity. It can be taken alone or with another weight-loss medication (tirzepatide).
Melbourne, VictoriaAges 18–65 - NCT07244341RecruitingPhase 1
Valemetostat and darolutamide for advanced prostate cancer
This trial tests a new combination of two drugs (valemetostat and darolutamide) for men with metastatic castration-resistant prostate cancer that has worsened after prior treatment. The goal is to see if the combination can slow cancer growth.
La Jolla, CaliforniaAges 18 years+ - NCT07243171RecruitingPhase 1/Phase 2
Oral Ecnoglutide for overweight or obesity
This trial tests an oral medication called Ecnoglutide to help people with overweight or obesity lose weight. It is for Chinese adults who are not diabetic and have a stable weight.
Beijing, Beijing MunicipalityAges 18–65 - NCT07241234RecruitingPhase 1
Study of an experimental drug for phenylketonuria (PKU)
This trial tests an investigational drug (AG-181) for people with PKU who have a specific genetic change (R408W mutation). It aims to check if the drug is safe and how it works in your body.
Indianapolis, IndianaAges 18–69 - NCT07247084RecruitingPhase 4
Tirzepatide for weight loss in adults with obesity
This trial tests if tirzepatide is more effective than standard obesity treatments for adults who have a BMI between 30 and 35 and one weight-related health condition, but do not have diabetes. The goal is to help you lose weight.
AltrinchamAges 18 years+ - NCT07244835RecruitingPhase 1
A study of DEG6498 for advanced solid tumors
This trial tests a new drug, DEG6498, for people with advanced solid tumors that have not responded to other treatments. It may be an option if your cancer has a BRAF mutation or is a type of liver cancer called HCC.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07240896RecruitingEarly Phase 1
Testing a new mRNA therapy for Wilson disease
This trial tests an experimental mRNA treatment (DSL101) for adults with Wilson disease. It's for people whose condition is stable on current therapy and who have certain genetic markers. The goal is to see if the new treatment can help the body process copper better and reduce the need for standard medicines.
Hefei, AnhuiAges 18 years+ - NCT07244393RecruitingPhase 1
Combination therapy for advanced prostate cancer
This trial tests a new combination therapy for advanced prostate cancer that has stopped responding to standard hormone treatments. It combines a radioactive targeted treatment (Lutetium-177 DGUL) with an immunotherapy drug (pembrolizumab) to see if it can shrink tumors and slow the cancer's growth.
SeoulAges 19 years+ - NCT07241416RecruitingPhase 3
Rezvilutamide for metastatic hormone-sensitive prostate cancer
This trial tests a new drug, rezvilutamide, combined with standard hormone therapy for men with prostate cancer that has spread but still responds to hormone treatment. The goal is to see if this drug helps control the cancer longer than the usual treatment alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07242664RecruitingPhase 1
Testing a new long-acting insulin in type 1 diabetes
This study compares a new investigational long-acting insulin (GZR33) to an approved one (insulin degludec) in people with type 1 diabetes. You would receive both insulins during an inpatient 'clamp' procedure to see how well they work, which may help find a more affordable or convenient option for daily blood sugar control.
NeussAges 18–64 - NCT07244003RecruitingPhase 4
Testing metformin with two newer diabetes drugs
This trial is testing if adding a combination of SGLT-2 inhibitor and GLP-1 receptor agonist to metformin can improve blood sugar control in people with type 2 diabetes who are not meeting their goals on metformin alone or with one other pill.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT06904690Recruiting
Health literacy training for older adults with type 2 diabetes
This trial tests whether an online training program can help older adults with type 2 diabetes better understand and use health information. It may improve your ability to manage your diabetes.
AnconaAges 60 years+ - NCT04242069Recruiting
Lifestyle coaching for overweight women trying to conceive
This trial tests a lifestyle program (using a smartphone) to help overweight women improve health before pregnancy while trying to conceive within the next year. It may help you and your partner build healthy habits before pregnancy.
Québec, QuebecAges 18–40 - NCT07247734RecruitingPhase 2
Colchicine for insulin sensitivity in type 1 diabetes
This trial tests whether a daily oral medication called colchicine can improve how your body responds to insulin. It is for people with type 1 diabetes who have ongoing low-level inflammation and are already using a continuous glucose monitor.
Gentofte MunicipalityAges 18–80 - NCT07245186Enrolling by invitation
Healthy living program for kidney decline
This study tests a program to help people with chronic kidney disease (CKD) stay healthy through diet tracking and other proactive steps. It focuses on people whose kidney function has declined but who are not yet on dialysis.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT07240844RecruitingPhase 4
Enavogliflozin for amyloid heart disease
This study tests a drug called enavogliflozin to see if it helps people with a specific type of heart failure caused by amyloid buildup. It may improve symptoms and daily function.
SeoulAges 19 years+ - NCT07248631Recruiting
Exercises and mindful walking for diabetic nerve pain
This study tests whether combining foot and ankle exercises with mindful walking can reduce pain and improve mobility in people with diabetic nerve damage in their feet.
Multan, Punjab ProvinceAges 3.3 years–6.3 years - NCT07245082Recruiting
Type 2 diabetes patient study
This study looks at people with type 2 diabetes to understand their health. If you join, you'll have simple measurements taken like height, weight, and grip strength.
Taipei, Zhongzheng DistAges 18 years+ - NCT07243262Recruiting
Breath test for pancreatic cancer detection
This trial tests whether a simple breath test can help detect pancreatic cancer earlier. If you have been referred for possible pancreatic cancer, you may be able to take part.
LondonAges 18 years+ - NCT07244458Recruiting
Peanuts and GLP-1 Medications Study
This study looks at how adding peanuts to your diet affects nutrition and health in people who are already taking weight-loss medications like Ozempic, Mounjaro, or Wegovy. It aims to see if peanuts can improve your diet quality and help with weight management.
Clevland, OhioAges 18–80 - NCT07241663Recruiting
Surgery for locally advanced pancreatic cancer
This trial is testing whether surgery can help people with a certain type of pancreatic cancer that is locally advanced but not yet spread. You may join if your cancer has shrunk or stayed stable after at least 4 months of chemotherapy and your medical team thinks surgery is possible.
PadovaAges 18 years+ - NCT07243821Recruiting
Metabolic syndrome and prediabetes study
This study looks at people with metabolic syndrome or prediabetes to understand how these conditions affect health. You may qualify if you have at least three signs of metabolic syndrome or if your blood sugar levels are higher than normal.
Taipei, Zhongzheng DistAges 18 years+ - NCT07241221Recruiting
Myo-inositol supplement for diabetes in pregnancy
This study tests whether taking a supplement called myo-inositol (a natural vitamin-like substance) during pregnancy can help manage blood sugar in women with type 2 diabetes. It may improve outcomes for you and your baby.
Singapore, SingaporeAges 21–45 - NCT07246408Recruiting
Cottonseed oil study for heart health
This study tests how taking cottonseed oil at certain times affects heart disease risk. It may help people with high cholesterol or who are overweight.
Athens, GeorgiaAges 25–75
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,616 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,939 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.