Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06435156RecruitingPhase 2
Sotagliflozin for Heart Failure in Type 1 Diabetes
This trial tests a medication called sotagliflozin for people who have both type 1 diabetes and heart failure symptoms. The goal is to see if it can improve how you feel and manage your heart and diabetes.
AberdeenAges 18–84 - NCT06426953Recruiting
Proteins in blood to predict confusion after surgery in older diabetics
This study looks at proteins in your blood (TGF-β and INS-PI3K-AKT) to see if they can predict confusion after surgery (postoperative delirium) in older adults with diabetes. It may help doctors identify who is at higher risk.
Duyun, GuizhouAges 65 years+ - NCT06427421Recruiting
Immune cells in children with recent type 1 diabetes
This study looks at immune cells in children who were recently diagnosed with type 1 diabetes. It involves one extra blood draw to better understand how the immune system attacks the pancreas. If you join, no new treatments are given—just observation and analysis of your child's immune cells.
ParisAges 6–18 - NCT06423235RecruitingPhase 4
Prunella oral liquid for thyroid nodules
This trial tests if an herbal liquid made from prunella can shrink benign thyroid nodules. It may be an option for people with solid, non-cancerous nodules who want to avoid surgery.
Chongqing, Chongqing MunicipalityAges 18–65 - NCT06440005RecruitingPhase 1
Testing AGX101 for advanced solid tumors
This study tests a new drug called AGX101 for people with advanced solid tumors that have not responded to other treatments. The goal is to see if it is safe and if it can shrink tumors or slow their growth.
Los Angeles, CaliforniaAges 18 years+ - NCT06429735Recruiting
Robot-implanted brain-computer interface for severe paralysis
This trial tests a brain-computer interface (a device that lets you control a computer with your thoughts) that is implanted by a robot. It is for people with severe paralysis who may benefit from a new way to communicate or control devices.
Phoenix, ArizonaAges 22–75 - NCT06439277RecruitingPhase 3
Tirzepatide for teens with obesity and related health problems
This study tests a medication called tirzepatide (a once-weekly injection) to help teenagers with obesity and related health conditions lose weight. It aims to see if the drug is safe and effective for this age group.
Los Angeles, CaliforniaAges 12–17 - NCT06437028Recruiting
Membrane allograft for diabetic foot ulcers
This trial tests a special membrane made from donated birth tissue (perinatal membrane) placed on a diabetic foot ulcer to help it heal faster. It's for people with diabetes whose foot ulcer hasn't healed after standard care for 4 weeks to a year.
Monroe, North CarolinaAges 18 years+ - NCT06431893Enrolling by invitationPhase 3
Long-term study of pegtibatinase for classical homocystinuria
This trial is a long-term follow-up study examining the safety and effectiveness of pegtibatinase for people with classical homocystinuria (HCU). It is open to those who have recently taken part in or finished the HARMONY or COMPOSE studies.
Phoenix, ArizonaAges 5–65 - NCT03760835RecruitingPhase 4
Once-daily hydrocortisone for adults with congenital adrenal hyperplasia
This trial studies whether a once-daily hydrocortisone tablet works as well as standard steroid treatment for adults with congenital adrenal hyperplasia caused by 21-hydroxylase deficiency. It aims to improve how safely and conveniently hormone replacement is taken each day.
NaplesAges 18 years+ - NCT05608772Recruiting
Revision weight-loss surgery after failed sleeve
This study looks at which revision surgery works best after a prior sleeve stomach operation that didn’t last. It tests switching to one of three procedures to help with weight regain, and it excludes more severe acid reflux cases.
Alexandria, Alexandria GovernorateAges 18–60 - NCT04794322Recruiting
Testing uterine fluid to help detect ovarian cancer
This study checks whether a sample of fluid from the uterus (uterine lavage) can help detect ovarian or fallopian tube cancer. You may join if you are having certain gynecologic surgeries or, in a smaller group, you have a BRCA1/2 mutation.
Little Rock, ArkansasAges 30 years+ - NCT06410976Recruiting
Study of hypochondroplasia in children
This study is for children with hypochondroplasia, a condition that causes short stature. It will look at how the condition changes over time and aims to better understand it, with the goal of finding new treatments.
Oakland, CaliforniaAges 2.5 years–16 years - NCT06400472RecruitingPhase 1
Study of drug Sofe-M for advanced solid tumors
This trial tests a new drug (Sofe-M) for people with certain advanced solid tumors, including ovarian, endometrial, cervical, lung, breast, pancreatic, or colorectal cancers. The goal is to find the best dose and see how well it works, potentially offering a new treatment option.
Scottsdale, ArizonaAges 18 years+ - NCT06411210RecruitingPhase 2
Weight loss medication for young adults with type 1 diabetes
This study tests whether a GLP-1 medication (a type of drug that helps with weight loss) can safely and effectively help young adults with type 1 diabetes who also have obesity. It aims to see if adding this treatment to insulin can improve weight and blood sugar control.
New Haven, ConnecticutAges 18–30 - NCT06414200Recruiting
Nutrition care at home for kids after hospital discharge
This study looks at how children who start nutritional support (like special drinks or tube feeding) in the hospital continue it at home after discharge. It aims to improve nutritional care for children from newborns to 18 years old.
Rotterdam, South HollandAges 1 week–18 years - NCT06402747RecruitingPhase 4
Comparing clopidogrel vs cilostazol for diabetes-related artery thickening
This trial compares two blood-thinning drugs (clopidogrel and cilostazol) to see which one better prevents artery problems in people with diabetes and thickened carotid arteries. It may help you if you have diabetes and are already on stable medications.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06412120RecruitingPhase 4
Niraparib safety and metabolism study in Black women
This trial tests a new maintenance therapy called niraparib for Black women who have finished initial treatment for advanced ovarian cancer and are in remission or partial response. It aims to see if the drug is safe and how your body processes it.
Fort Lauderdale, FloridaAges 18 years+ - NCT06411691RecruitingPhase 1
Vaccine plus immunotherapy for KRAS-mutant cancers
This trial tests a cancer vaccine designed to target KRAS-mutated tumors, combined with two immunotherapy drugs, for people with advanced colorectal or pancreatic cancer. It may help the immune system recognize and attack cancer cells.
Baltimore, MarylandAges 18 years+ - NCT06408077Recruiting
How sodium levels are managed in kidney failure
This study looks at how the body handles salt (sodium) in people with end-stage kidney disease who are on dialysis. If you join, researchers will test how your body responds to changes in fluids and salt levels.
CologneAges 18 years+ - NCT06414096RecruitingPhase 1
Pulsatile FSH study for women with obesity or low ovarian reserve
This study tests a new way to give a fertility hormone (FSH) in pulses through a small tube to see if it helps women with obesity or low egg reserve have better egg development with fewer health risks. It may improve fertility treatment outcomes for these women.
Aurora, ColoradoAges 19–37 - NCT06408961Recruiting
EVs in Obesity and Cardiometabolic Disease
This study looks at tiny particles released by cells (called extracellular vesicles, or EVs) in people with obesity and related heart health issues. Researchers want to see if these particles are different in people with obesity and diabetes, which could help find new ways to treat or prevent heart problems.
Boston, MassachusettsAges 18 years+ - NCT06407024Recruiting
Laparoscopic vs robotic surgery for adrenal gland removal
This trial compares two types of minimally invasive surgery (laparoscopic vs robotic) to remove an adrenal gland. It aims to see which approach leads to better recovery and outcomes.
Cleveland, OhioAges 18–75 - NCT06403189Recruiting
Studying choroid plexus function in brain diseases
This study looks at how a part of the brain called the choroid plexus works in people with different brain conditions. It may help find better ways to diagnose or treat these diseases.
ParisAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.