Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06426563Recruiting
Comparing microwave vs radiofrequency for benign thyroid nodules
This study compares two heat-based treatments—microwave ablation (MWA) and radiofrequency ablation (RFA)—for shrinking benign thyroid nodules that are moderate in size. If you have a non-cancerous, solid nodule at least 2 cm wide, this trial may help you avoid surgery.
Hong Kong, Hong KongAges 18 years+ - NCT06425796Recruiting
Body fat and iron needs in pregnancy study
This study looks at how a mother's body fat might affect her iron needs during pregnancy. If you join, you may stop taking any current multivitamins to help researchers learn more about when iron supplements are truly needed.
Coleraine, Co LondonderryAges 18 years+ - NCT06425016Recruiting
Robot-assisted vs. traditional sleeve gastrectomy
This study compares two types of weight-loss surgery: one done with the help of a robot and the other done by hand (laparoscopic). Both are types of sleeve gastrectomy, where the stomach is reduced in size. If you qualify for sleeve gastrectomy, this trial may help doctors learn which method works better.
Cleveland, OhioAges 18–70 - NCT06420661Enrolling by invitation
School program for children with type 1 diabetes
This study tests a special program called SPACE that helps children with type 1 diabetes by working together with their school nurse and diabetes team. The goal is to improve diabetes care and support at school.
Pittsburgh, PennsylvaniaAges 5–12 - NCT06436326Recruiting
Continuous glucose monitoring for gestational diabetes
This study tests whether using a continuous glucose monitor (a small sensor that checks your blood sugar all day) can improve outcomes for you and your baby during gestational diabetes. It may help you manage your blood sugar more easily and reduce risks.
HsinchuAges 18 years+ - NCT06420973RecruitingPhase 2
Testing RC48 for ovarian cancer returning after platinum treatment
This trial tests a new drug, RC48, for people with ovarian cancer that came back after responding well to platinum chemotherapy. RC48 targets the HER2 protein on cancer cells, which may stop the tumor from growing. Researchers want to see if it's safe and works better than current options.
Beijing, Beijing MunicipalityAges 18–75 - NCT06423326RecruitingPhase 2
Chemotherapy before surgery for pancreatic cancer
This trial tests a combination of three chemotherapy drugs given before surgery for pancreatic cancer that is removable or borderline removable. The goal is to shrink the tumor to make surgery more successful.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06424015Recruiting
Insulin pulses during fasting study
This study tests how insulin, given in pulses or continuously, affects your body during a fast. It may help researchers understand better ways to manage blood sugar in people with early blood sugar issues.
Rochester, MinnesotaAges 25–65 - NCT06437782Recruiting
Diabetes health literacy study in Reunion Island and France
This study looks at how well people with diabetes understand health information and make decisions about their care. It is being done in hospitals in Reunion Island and France to help improve diabetes education and support.
Saint-DenisAges 18 years+ - NCT06421532Enrolling by invitationPhase 2
Testing LXB to clear protein buildup in CAA
This study tests whether the drug LXB (sodium oxybate) can help clear abnormal protein buildup in the brain's small blood vessels (CAA). Participants will take LXB nightly for 8 weeks and have MRIs and spinal taps to measure changes.
LeidenAges 30 years+ - NCT06422455Recruiting
Genetic testing for underserved cancer patients
This study offers free genetic testing to cancer patients and their healthcare providers. It aims to help people who may not have easy access to genetic testing understand their cancer risk.
Los Angeles, CaliforniaAges 18 years+ - NCT06426693Recruiting
Brain training for food cravings
This study tests a brain-training technique called neurofeedback to help reduce food cravings. You'll get MRI scans while learning to control brain activity related to cravings.
New Haven, ConnecticutAges 18–60 - NCT06435156RecruitingPhase 2
Sotagliflozin for Heart Failure in Type 1 Diabetes
This trial tests a medication called sotagliflozin for people who have both type 1 diabetes and heart failure symptoms. The goal is to see if it can improve how you feel and manage your heart and diabetes.
AberdeenAges 18–84 - NCT06439667Enrolling by invitation
Home Exercise Program for Diabetic Foot Ulcers
This trial tests a home exercise program delivered by video to help heal diabetic foot ulcers. It's designed for people who can walk on their own and have a relatively new ulcer.
Los Angeles, CaliforniaAges 18 years+ - NCT06435260RecruitingPhase 2
Short radiation, chemo, and immunotherapy before pancreas cancer surgery
This trial tests a short course of radiation combined with chemo and the immunotherapy drug camrelizumab before surgery for pancreatic cancer. It aims to shrink tumor to make removal easier and improve outcomes.
Shijiazhuang, HebeiAges 18–75 - NCT06426277Recruiting
Brazilian diabetes prevention program
This study tests a program that helps people with prediabetes make healthy lifestyle changes to prevent type 2 diabetes. You would get support through your own device at home, with no need for in-person visits.
Goiânia, GoiásAges 18 years+ - NCT06424106Recruiting
Glucagon & fasting insulin in people without type 2 diabetes
This study looks at how glucagon affects insulin release and blood sugar in people who do not have type 2 diabetes. It may help us understand normal glucose control better.
Rochester, MinnesotaAges 25–65 - NCT06427239RecruitingPhase 1/Phase 2
HRS-4642 and adebrelimab for advanced pancreatic cancer
This trial tests a combination of two drugs (HRS-4642 and adebrelimab) for people with advanced pancreatic cancer that has not responded to standard treatment. The goal is to see if this combination can shrink tumors or slow the disease.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06430528Recruiting
Osilodrostat and steroid replacement for Cushing syndrome
This trial tests a new approach, called 'block-and-replace', for treating Cushing syndrome. You will take osilodrostat to lower high cortisol levels, along with a glucocorticoid (a steroid) to replace what your body needs. This study may help control the disease if surgery hasn't worked or isn't an option.
Ann Arbor, MichiganAges 18–75 - NCT06428097RecruitingPhase 1
Thyroid hormone before heart transplant
This study tests whether giving a thyroid hormone supplement called levothyroxine before a heart transplant can help with recovery. It is for people already listed for a heart transplant who do not have thyroid problems.
San Francisco, CaliforniaAges 18 years+ - NCT06427421Recruiting
Immune cells in children with recent type 1 diabetes
This study looks at immune cells in children who were recently diagnosed with type 1 diabetes. It involves one extra blood draw to better understand how the immune system attacks the pancreas. If you join, no new treatments are given—just observation and analysis of your child's immune cells.
ParisAges 6–18 - NCT06432790Recruiting
In-person vs online healthy living and asthma program for kids
This study compares two programs for helping children with asthma who are overweight or obese — one that is held in person and another that is offered online. It tests whether learning about healthy habits and asthma management works better when done face-to-face or on a computer.
Boston, MassachusettsAges 4–17 - NCT06430541RecruitingPhase 1
Psilocybin therapy for fear of cancer recurrence
This trial tests if psilocybin-assisted therapy can help reduce the intense worry that cancer might come back. It is for people who have finished their main treatments for early-stage breast cancer or advanced ovarian cancer.
Aurora, ColoradoAges 21 years+ - NCT06423963Recruiting
Exercise and nutrition before pancreatic cancer surgery
This trial tests whether a home-based exercise and nutrition program can help people with pancreatic cancer get stronger before surgery. It’s designed for those who are not already doing regular strength training.
Tampa, FloridaAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.