Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,333
- Phase 2607
- Phase 1559
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 384
Top conditions
- Obesity620
- Ovarian Cancer335
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight124
- Breast Cancer110
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer90
- Pancreas Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- Eli Lilly and Company41
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas158
- Massachusetts150
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07577817RecruitingEarly Phase 1
Safety Study of CTX001 in Healthy Adults
This early-stage study tests a new experimental drug called CTX001 in healthy volunteers to check if it is safe and well-tolerated. Researchers will also measure how your body processes the drug and how it affects certain blood markers.
Melbourne, VictoriaAges 18–55 - NCT07583563Recruiting
Observational study of octreotide depot injections for acromegaly
This study watches how patients with acromegaly respond to octreotide, a medication given as injections under the skin. Researchers will collect information about how well the treatment works and any side effects you experience.
AachenAges 18 years+ - NCT07578584RecruitingPhase 1
Safety study of NNC0497-0040 in healthy and overweight adults
This early-stage study tests a new investigational medication in three groups: healthy adults with normal weight, adults who are overweight or obese, and men with type 1 diabetes who are also overweight. The research aims to understand how safe the medication is and how the body processes it.
NeussAges 18–55 - NCT07581431RecruitingPhase 1
Testing ISM8969 in healthy and obese adults with heart disease risk
This early-stage trial tests a new drug called ISM8969 to see if it's safe and how the body handles it. Participants are either healthy adults or adults who are overweight with risk factors for heart disease, like high blood pressure or high cholesterol.
Melbourne, VictoriaAges 18–80 - NCT07579936RecruitingPhase 2
SAL056 bone-strengthening treatment for postmenopausal osteoporosis
This study tests a new injectable medication called SAL056 to strengthen bones and prevent fractures in postmenopausal women with osteoporosis. Researchers want to find the best dose and how often to give it.
Beijing, Beijing MunicipalityAges 45–80 - NCT07579702Recruiting
Omnipod 6 Versus Omnipod 5 Insulin Pump System
This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.
Los Angeles, CaliforniaAges 14–75 - NCT07581808RecruitingPhase 4
Two cholesterol drugs for heart disease prevention
This study tests two newer cholesterol-lowering medications (inclisiran and alirocumab) together in people who've had heart problems or strokes and cannot tolerate standard cholesterol drugs. The goal is to see if this combination safely lowers cholesterol further and reduces future cardiovascular events.
LjubljanaAges 18 years+ - NCT07577765Recruiting
Keeping Weight Off With a Personalized Plan
This study tests a customized approach to help you maintain weight loss you've already achieved. Researchers will use your smartphone to send you tailored support and track your progress over time.
Salt Lake City, UtahAges 18–65 - NCT07584577Recruiting
Nutrition Support During Cancer Treatment Before Surgery
This study tests whether a special feeding tube placed in the small intestine helps patients recover better after surgery for esophageal or stomach cancer. The tube delivers nutrition directly during chemotherapy or radiation before surgery.
PessacAges 18 years+ - NCT07585669Recruiting
Omega-3 Supplements for New Celiac Disease Patients
This study tests whether omega-3 fatty acids (a type of fish oil supplement) can reduce inflammation and improve gut health in people newly diagnosed with celiac disease. Participants will follow a gluten-free diet while taking the supplement to see if it helps their body heal.
Santiago, Metropolitan RegionAges 18–65 - NCT07585994Recruiting
Probiotic supplement for long-standing type 1 diabetes
This study tests whether taking a specific probiotic (a beneficial bacteria) for 4 weeks can improve immune function and metabolism in people who have had type 1 diabetes for at least 5 years. Researchers believe this probiotic may help the body's remaining insulin-producing cells work better.
AmsterdamAges 18 years+ - NCT07583459Recruiting
Summer childcare program to prevent unhealthy weight gain in preschoolers
This study tests whether a center-based childcare program during summer can help prevent excessive weight gain in preschool-aged children from low-income families. The program focuses on healthy eating and activity habits during the summer months when children are not in school.
Columbia, South CarolinaAges 3–5 - NCT07579078Enrolling by invitation
Vitamin D and Brain Activity in Women With Depression
This study tests whether vitamin D supplements can improve brain wave patterns in women diagnosed with depression who have low vitamin D levels. Researchers will measure brain activity using EEG (a non-invasive test that records electrical signals from the brain) before and after vitamin D treatment.
DhakaAges 20–40 - NCT07582718Recruiting
High-Intensity Interval Training for Fitness in Adults
This study tests whether intense, short bursts of exercise can improve fitness in adults who are overweight. You'll do whole-body workouts designed to boost cardiovascular health and physical performance.
BrusselsAges 18–55 - NCT07585487Recruiting
How medications work in children of different weights during surgery
This study measures how two common medications—paracetamol (pain reliever) and cefazolin (antibiotic)—move through the body differently in children who are normal weight versus overweight. Researchers will take small blood samples during routine surgery to understand the best doses for each child.
GhentAges 2–15 - NCT07578090Recruiting
Managing high blood pressure, blood sugar, and cholesterol
This study tests a new approach to helping people manage chronic conditions like high blood pressure, high blood sugar, or high cholesterol. Researchers will work with participants to improve their care and quality of life.
New Taipei CityAges 18 years+ - NCT07578597Enrolling by invitation
Pregnancy and Baby Health After Weight-Loss Surgery
This study compares how pregnancy and newborn health differ between women who had weight-loss surgery (gastric bypass or sleeve gastrectomy) and women who didn't. Researchers follow both mother and baby to understand potential risks and benefits.
OdenseAges 18 years+ - NCT07584473Recruiting
Testing for Non-Celiac Wheat Sensitivity in Celiac Disease Relatives
This study investigates whether relatives of celiac disease patients who have digestive symptoms and other health concerns might have non-celiac wheat sensitivity or irritable bowel syndrome. Researchers will perform a small intestinal biopsy and dietary testing to understand the connection between wheat sensitivity and symptoms in this family group.
Palermo, PAAges 18 years+ - NCT07582562Recruiting
Thyroid Surgery and Low Calcium Risk Factors
This study examines why some patients develop low calcium levels (hypoparathyroidism) after surgery to remove both sides of the thyroid gland. By understanding these risk factors, doctors hope to better predict and prevent this complication.
TallinnAges 18 years+ - NCT07581145RecruitingPhase 3
Semaglutide for Faster Healing of Diabetic Foot Ulcers
This study tests whether a diabetes medication called semaglutide can help foot ulcers heal faster in people with type 2 diabetes. If it works, it could offer a new treatment option for a common and serious diabetes complication.
CopenhagenAges 18–90 - NCT07578103Recruiting
Dairy vs Plant-based Yogurt for Weight and Bone Health
This study compares how dairy yogurt and plant-based yogurt affect weight, body composition, bone strength, and gut bacteria in postmenopausal women. It may help identify which type of yogurt is better for overall health during this life stage.
Québec, QuebecAges 40 years+ - NCT07583940Recruiting
Energy Intake and Blood Pressure in College Athletes
This study looks at whether not eating enough calories affects blood pressure in Division I college athletes. Researchers want to understand if improving nutrition can help prevent high blood pressure in young athletes.
Greensboro, North CarolinaAges 18–26 - NCT07583823Recruiting
Higher-Rate Pacing for Heart Amyloid Disease
This study tests whether pacing your heart at a faster rate helps people with cardiac amyloidosis (a condition where abnormal protein builds up in the heart). If you have a pacemaker and cardiac amyloidosis, this research might help doctors understand the best pacing settings for you.
Minneapolis, MinnesotaAges 18 years+ - NCT07585032Recruiting
Ultrasound-guided heat treatment for pancreatic insulinoma tumors
This trial tests a minimally invasive procedure that uses heat (delivered through an ultrasound scope) to treat insulinoma—a hormone-producing pancreatic tumor that causes low blood sugar. The procedure may offer a less invasive alternative to surgery.
GothenburgAges 15–80
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,855 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.