Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,333
- Phase 2607
- Phase 1559
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 384
Top conditions
- Obesity620
- Ovarian Cancer335
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight124
- Breast Cancer110
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer90
- Pancreas Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- Eli Lilly and Company41
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas158
- Massachusetts150
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07585669Recruiting
Omega-3 Supplements for New Celiac Disease Patients
This study tests whether omega-3 fatty acids (a type of fish oil supplement) can reduce inflammation and improve gut health in people newly diagnosed with celiac disease. Participants will follow a gluten-free diet while taking the supplement to see if it helps their body heal.
Santiago, Metropolitan RegionAges 18–65 - NCT07582562Recruiting
Thyroid Surgery and Low Calcium Risk Factors
This study examines why some patients develop low calcium levels (hypoparathyroidism) after surgery to remove both sides of the thyroid gland. By understanding these risk factors, doctors hope to better predict and prevent this complication.
TallinnAges 18 years+ - NCT07585994Recruiting
Probiotic supplement for long-standing type 1 diabetes
This study tests whether taking a specific probiotic (a beneficial bacteria) for 4 weeks can improve immune function and metabolism in people who have had type 1 diabetes for at least 5 years. Researchers believe this probiotic may help the body's remaining insulin-producing cells work better.
AmsterdamAges 18 years+ - NCT07578103Recruiting
Dairy vs Plant-based Yogurt for Weight and Bone Health
This study compares how dairy yogurt and plant-based yogurt affect weight, body composition, bone strength, and gut bacteria in postmenopausal women. It may help identify which type of yogurt is better for overall health during this life stage.
Québec, QuebecAges 40 years+ - NCT06724744Recruiting
Can a hand technique help breathing in older women with diabetes?
This study is testing a gentle hands-on technique for the diaphragm (the main breathing muscle) to see if it can improve breathing in older women with type 2 diabetes. It may help if you have mild breathing problems and meet the health criteria listed.
Al Mansurah, DakahlyaAges 65–70 - NCT06722391Recruiting
Electrical stimulation to improve metabolism in overweight adults
This study tests whether a non-invasive electrical stimulation treatment can help improve metabolism in people who are overweight and inactive. It may be an option for those who do not exercise regularly.
El Paso, TexasAges 18–65 - NCT00948116Recruiting
Blood and urine tests to predict kidney injury in diabetes
This study checks whether a set of blood and urine tests can predict “acute kidney injury” (a sudden worsening of kidney function) earlier in people with diabetes who are undergoing a heart procedure. If the tests work, they may help doctors spot kidney trouble sooner and protect your kidneys.
LondonAges 18 years+ - NCT03988764Recruiting
Checking monogenic diabetes wrongly labeled as type 1
This trial looks at people who were diagnosed with diabetes before age 25 as either type 1 or “not sure which type.” It may help confirm whether the cause is genetic (monogenic) rather than type 1, which can change treatment choices.
Montreal, QuebecAges 1 day–25 years - NCT06575790Recruiting
Comparing simplified meal boluses to carb counting for teens with automated insulin pumps
This study tests if a simpler way of calculating meal insulin works as well as counting carbohydrates for teens using hybrid closed loop (automated insulin) systems. If you're a teen with type 1 diabetes and use an automated pump, this trial could help find an easier mealtime routine.
Aurora, ColoradoAges 14–26 - NCT06456827Recruiting
Bite force and bone changes after braces in different face types
This trial compares how bite force and bone turnover markers change during the retention phase (after braces) in people with high-angle and low-angle face types. It may help understand why some people have more relapse after braces.
Rohtak, HaryanaAges 18–45 - NCT06725940Recruiting
PET scan to check treatment response in breast cancer
This trial uses a special PET scan to see how well your breast cancer is responding to neoadjuvant therapy (treatment given before surgery). The goal is to help doctors personalize your care by checking if the cancer is shrinking.
ShanghaiAges 18–65 - NCT06725511Recruiting
Wellness program for employees with metabolic syndrome
This study tests a wellness program designed for employees with metabolic syndrome, a cluster of conditions like high blood pressure and high blood sugar. The program aims to improve health through outreach and support.
Secaucus, New JerseyAges 21 years+ - NCT07574333Recruiting
Breathing Training to Help Type 2 Diabetes Management
This study tests whether special breathing exercises that alternate between low and high oxygen levels can help people with type 2 diabetes manage their condition better. Researchers want to see if short or longer courses of this training improve blood sugar control and overall health.
MoscowAges 50–74 - NCT07575399RecruitingPhase 3
Switching to a New Weight-Loss Medication From Current GLP-1
This trial tests whether switching from your current GLP-1 medication (like Ozempic or Wegovy) to a new drug called maridebart cafraglutide works as well or better for weight management. You must have already lost at least 10% of your body weight on your current GLP-1 and be doing well with it.
Pelham, AlabamaAges 18–99 - NCT07571005RecruitingPhase 3
Testing a New Weight-Loss Medicine for Sleep Apnea
This study tests whether a new injectable medicine called NNC0487-0111 helps people with excess weight and moderate-to-severe obstructive sleep apnea (a condition where breathing stops repeatedly during sleep) lose weight and improve their sleep apnea—without needing a CPAP machine. The goal is to see if better weight loss can reduce sleep apnea symptoms.
San Diego, CaliforniaAges 18 years+ - NCT07571200RecruitingPhase 1
Study of LY4256984 for ALS in Previous Trial Participants
This is a follow-up study for people with ALS who have already completed another Eli Lilly ALS treatment trial. Researchers want to continue testing a new drug (LY4256984) in people who tolerated the previous treatment well.
LeuvenAges 18–80 - NCT07571174RecruitingPhase 1
ALS Study: Testing a New Drug in Spinal Fluid
This is a follow-up study for people with ALS (a disease affecting nerve and muscle control) who completed a previous trial called OWAA. Researchers want to test how a new experimental drug called LY4256984 affects the spinal fluid around your brain and spine, which may help them understand if it could slow disease progression.
LeuvenAges 18–80 - NCT07573059Recruiting
Safety study of a test system for Loargys-treated patients
This study evaluates whether a new test system is safe to use in patients who are already taking Loargys (a medicine for a rare condition called ARG1-D, which affects how the body processes a protein building block called arginine). The study simply observes how the test system works in people already on this treatment.
Atlanta, GeorgiaAges birth–100 years - NCT07568678RecruitingPhase 1
Testing HMS1005 in adults with type 2 diabetes
This study tests a new medicine called HMS1005 in people with type 2 diabetes. Researchers want to see how safe it is and how the body responds to different doses. You may qualify if you have type 2 diabetes that is either untreated or controlled with common diabetes medications.
Miami, FloridaAges 18–65 - NCT07570992RecruitingPhase 1
Safety study of NNC1679-0001 in healthy people and people with type 2 diabetes
This study tests the safety of a new medicine called NNC1679-0001 in healthy adults and those with type 2 diabetes. The goal is to see if it is safe before larger trials.
GrazAges 18–64 - NCT07571109RecruitingPhase 3
Weight Loss Medicine for Sleep Apnea on CPAP
This study tests a new injectable medicine (NNC0487-0111) to help people lose weight and improve obstructive sleep apnea (a breathing condition during sleep). You must already be using a CPAP machine (positive airway pressure device) for your sleep apnea.
Gilbert, ArizonaAges 18 years+ - NCT07570758RecruitingPhase 2
Testing ERX1000 to Help Adults Manage Obesity
This study tests whether a new medication called ERX1000 is safe and well-tolerated in adults with obesity. The trial will help doctors understand if this treatment could be helpful for weight management.
Louisville, KentuckyAges 18–60 - NCT05349227Recruiting
After-cancer digital coaching and wearable tracking outcomes study
This study tests a digital health coaching program (using phone/tablet check-ins and wearable data) to understand health and quality-of-life outcomes after cancer treatment. It may help you learn healthy habits and track progress over time.
Gainesville, FloridaAges 18 years+ - NCT05859022Recruiting
Bariatric treatment methods compared for diabetes and metabolism
This trial compares a less invasive heart/artery-based bariatric treatment (bariatric arterial embolization) with standard weight-loss surgery to see how they affect metabolism and type 2 diabetes. You might be considered if you have obesity with type 2 diabetes and have not had prior bariatric surgery.
LisbonAges 18–75
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,855 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.