Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,609 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1560
- Phase 3418
- Phase 4318
- Phase 1/Phase 2287
- Phase 2/Phase 384
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome126
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas159
- Massachusetts150
- New York143
- Colorado115
- Pennsylvania112
Recruiting studies7,609 total
- NCT07529704Recruiting
Early help for healthy weight in young children
This trial tests a program to help families with young children build healthy habits and prevent obesity. It focuses on families facing challenges like low income or housing issues.
Burgos, Castille and LeónAges Any age - NCT07528105RecruitingEarly Phase 1
CAR-T Cell Therapy for Early-Stage Type 1 Diabetes
This early-stage trial tests a new type of immune cell therapy (CAR-T cells) designed to stop the body's immune system from attacking insulin-producing cells in type 1 diabetes. The goal is to help preserve remaining pancreas function in people with early-stage disease.
ShanghaiAges 18–40 - NCT07531459Recruiting
Understanding Health Behaviors in Type 2 Diabetes
This study is creating and testing a new tool to measure healthy behaviors in people with type 2 diabetes. Researchers want to understand how patients manage their diabetes day-to-day and how healthcare workers can better support them.
Changzhou, JiangsuAges 18 years+ - NCT07532135RecruitingPhase 1
Mulberry leaf extract safety and blood sugar effects
This study tests whether a mulberry leaf supplement is safe and helps control blood sugar in people without diabetes. Researchers will monitor your health and blood work to see if this natural extract is beneficial.
BangkokAges 18 years+ - NCT07528365Recruiting
Urea Treatment for Low Sodium Levels From SIAD
This trial tests whether urea can help treat dangerously low sodium levels in patients with SIAD (a condition where the body retains too much water) who haven't responded to drinking less fluid. Urea is a naturally occurring substance that may help restore normal sodium balance.
Turin, Piedmont, ItalyAges 18 years+ - NCT07530809Recruiting
Time-Restricted Eating for Fatty Liver Disease
This study tests whether eating within a limited time window each day can improve fatty liver disease (a buildup of fat in the liver). If you have moderate-to-advanced fatty liver disease and are overweight, this trial might help you learn if changing when you eat—rather than what you eat—can reduce liver fat and improve your health.
Homburg, SaarlandAges 18–75 - NCT07533799Recruiting
Swedish BioFINDER Sleep Study: Brain imaging in RBD and Parkinson's
This study examines brain changes in people with REM sleep behavior disorder (acting out dreams during sleep) and early Parkinson's disease using brain imaging scans. Researchers want to understand how sleep problems relate to Parkinson's development and find early warning signs.
MalmöAges 50–100 - NCT07529626Recruiting
Stress and Pancreatic Cancer Disease Outcomes Study
This research study examines how chronic psychological stress (long-term worry, anxiety, or emotional burden) affects the course of pancreatic cancer and related pancreatic diseases. Understanding this connection may help doctors provide better support and treatment plans for patients.
Changsha, HunanAges 18 years+ - NCT07530718Recruiting
How Weight-Loss Surgery Affects Body Composition in MS Patients
This study follows people with multiple sclerosis (MS) who are having weight-loss surgery to understand how their body composition—the balance of muscle, fat, and bone—changes after surgery. The research may help doctors better support MS patients through weight-loss surgery.
Baton Rouge, LouisianaAges 18 years+ - NCT07525622Recruiting
Learning carbohydrate counting to manage prediabetes
This study teaches adults with prediabetes how to count carbohydrates in their diet as a way to help manage blood sugar without medication. You'll learn practical skills to make healthier food choices.
Istanbul, PendikAges 18 years+ - NCT07533604Recruiting
Using a smartphone app and glucose monitor for type 2 diabetes
This 8-week study tests whether using a smartphone app called SnapD along with a continuous glucose monitor (a small sensor that tracks your blood sugar throughout the day) helps people with type 2 diabetes manage their condition better. You'll keep taking your current diabetes medications without changes.
Bangkok, BangkokAges 18–65 - NCT07529366Recruiting
Pharmacist-Led Glucose Monitoring for Prediabetes
This study tests whether wearing a continuous glucose monitor (a small sensor that tracks blood sugar throughout the day) with help from a pharmacist can help people with prediabetes better understand and manage their blood sugar levels. The goal is to see if this approach helps prevent or delay the development of type 2 diabetes.
Tampa, FloridaAges 18–70 - NCT06398795Recruiting
Dual-port thyroid surgery through the armpit
This trial tests a new type of minimally invasive thyroid surgery that uses two small openings under your collarbone to remove thyroid growths. It may be a good option if you want less visible scarring from your thyroid operation.
Wenzhou, ZhejiangAges 18–90 - NCT06754423Recruiting
Registry for men with CAH (21-hydroxylase deficiency)
This trial is creating a registry to track adult males with congenital adrenal hyperplasia (CAH) from 21-hydroxylase deficiency. It helps doctors learn more about the condition and how it changes over time.
BolognaAges 18 years+ - NCT06755775Recruiting
PET scan to predict immunotherapy success in DLBCL
This trial uses a special PET scan to see if a protein called Granzyme B can predict how well immunotherapy will work for people with DLBCL. It aims to help doctors know earlier if treatment is effective.
ShanghaiAges 18 years+ - NCT07523529RecruitingPhase 1/Phase 2
CAR-T Cell Therapy for Advanced Solid Tumors
This trial tests a new type of immune cell therapy (CAR-T cells) designed to target two markers on cancer cells at once. The goal is to help patients with advanced solid tumors where standard treatments have stopped working or aren't an option.
Shenzhen, GuangdongAges 18–75 - NCT07517198RecruitingPhase 1
EXS74539 Study for Advanced Solid Tumors
This is an early-stage study testing a new cancer drug called EXS74539 to find the right dose and see how well it works in people with various advanced solid tumors. The drug may help patients whose cancers have stopped responding to standard treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT07524907Recruiting
Nutrition supplement study for children with slow growth
This study tests whether a special nutrition supplement can help young children (ages 1–5) who are not growing as expected. Researchers will work with Children International centers in the study area to see if the supplement helps children grow taller and healthier.
Kansas City, MissouriAges 1–5 - NCT07522073RecruitingPhase 3
Chemotherapy with or without KRAS inhibitor for pancreatic cancer
This study tests whether adding a new drug called INCB161734 to standard chemotherapy helps people with advanced pancreatic cancer that has a specific genetic change (KRAS G12D mutation). You would be randomly assigned to receive either chemotherapy alone or chemotherapy plus the new drug.
Birmingham, AlabamaAges 18 years+ - NCT07521475Recruiting
Fully Closed Loop Insulin Pump for Type 2 Diabetes
This study tests a new automated insulin pump system (Omnipod) that adjusts insulin doses on its own throughout the day for people with type 2 diabetes. The goal is to see if it helps keep blood sugar levels more stable while reducing the burden of manual insulin management.
Los Angeles, CaliforniaAges 18–75 - NCT07521631RecruitingPhase 2
HDM1005 versus Tirzepatide for weight management in obese adults
This study tests whether a new injectable medication called HDM1005 works as well as tirzepatide (a GLP-1 drug) for weight loss in adults with obesity but no diabetes. Both medications work similarly in the body to help control appetite and weight.
ShanghaiAges 18–65 - NCT07524322RecruitingPhase 1
RGT-490 for Advanced Cancers With PIK3CA Mutations
This study tests a new drug called RGT-490 in patients with advanced solid tumors (cancers that have spread or cannot be removed by surgery) that have a specific genetic change called a PIK3CA mutation. The drug is designed to block a protein involved in cancer cell growth.
Los Angeles, CaliforniaAges 18 years+ - NCT07518004Recruiting
ROME GS System Study for diabetes glucose monitoring
This study tests the ROME GS System, a glucose monitoring device that measures blood sugar levels. The system includes a sensor placed under the skin and a transmitter worn on the body. If you have diabetes and want to help evaluate a new way to track your blood sugar, this trial may be for you.
Escondido, CaliforniaAges 18 years+ - NCT07523971Recruiting
Pitavastatin/Ezetimibe for High Cholesterol and Metabolic Syndrome
This study watches how well a combination cholesterol medication (pitavastatin and ezetimibe) works in people who have high cholesterol and metabolic syndrome (a cluster of health issues including high blood pressure, blood sugar, and cholesterol). You'll be monitored over time to see if the medication helps and is safe for you.
DaejeonAges 19 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,609 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,903 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.