Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,016 recruiting studies in this area right now.
By phase
- Not applicable2,561
- Phase 2123
- Phase 4112
- Phase 382
- Phase 182
- Phase 1/Phase 234
- Phase 2/Phase 322
Top conditions
- Traumatic Brain Injury151
- Spinal Cord Injuries142
- Spinal Cord Injury105
- Stroke64
- Trauma51
- Mild Traumatic Brain Injury40
- Amputation38
- Anterior Cruciate Ligament Injuries37
- Radiotherapy Side Effect37
- Hip Fractures36
- Rotator Cuff Tears35
- Spinal Cord Injuries (SCI)34
- Burns28
- Carpal Tunnel Syndrome28
- Anterior Cruciate Ligament Rupture27
- Cardiotoxicity26
- Carpal Tunnel Syndrome (CTS)26
- Breast Cancer25
Leading sponsors
- VA Office of Research and Development34
- Cairo University22
- Kessler Foundation20
- Johns Hopkins University19
- University of Miami19
- Zimmer Biomet19
- University of Florida18
- University of British Columbia17
- Mayo Clinic16
- Riphah International University16
Where studies are running
- California159
- Texas91
- Florida79
- New York78
- Illinois57
- Massachusetts55
- Pennsylvania51
- Minnesota45
- Ohio43
- Colorado41
Recruiting studies3,016 total
- NCT04708613Recruiting
Brain testing study for former football players and controls
This study looks at how the brain and thinking may be affected by playing professional football, using brain scans and thinking tests. It also compares former players with similar men who did not play organized football beyond high school.
Pittsburgh, PennsylvaniaAges 29–59 - NCT04685772Recruiting
Medrol Dose Pack for new concussion headache relief
This trial tests whether a Medrol “dose pack” (a short course of steroid medicine taken by mouth) can reduce acute headache pain after a concussion. It may help people whose concussion headaches are frequent and severe soon after injury.
Manhasset, New YorkAges 18 years+ - NCT04743765Recruiting
Faster hip fracture care for people with heart stress signs
This study looks at an “accelerated” hospital plan to get surgery and treatment started sooner for some people with a hip fracture who also show signs of heart stress in blood tests. It may help reduce delays and improve safety during urgent hip fracture care.
Chandler, ArizonaAges 45 years+ - NCT04725201RecruitingPhase 4
IV heparin study after finger or hand reattachment
This study looks at whether giving an IV blood thinner called unfractionated heparin after finger/hand reattachment and restoring blood flow improves healing and safety. If you were accepted into the CEVARMU replant/revascularization program, this trial may be testing a standard-after-surgery medicine approach.
Montreal, QuebecAges 14 years+ - NCT04733599Recruiting
Spinal cord stimulation for long-term arm nerve pain
This trial tests whether a high-frequency spinal cord stimulator can reduce long-term nerve pain in the arm after a brachial plexus injury. It may help people whose pain has lasted at least 3 months despite standard treatments.
Jacksonville, FloridaAges 18 years+ - NCT04726306Enrolling by invitation
Compare two scoring systems for hyperbaric care quality
This study compares two different ways to rate how well hyperbaric (pressure-based) medical care is being done. It aims to find which scoring method is more accurate and consistent.
Sleepy Hollow, New YorkAges Any age - NCT04700527RecruitingPhase 1/Phase 2
Nutritional supplement for reducing side effects from radiation to the belly or pelvis
This trial is studying whether a nutritional supplement (a type of short-chain fatty acid) can help reduce the side effects of radiation therapy for cancers in the abdomen or pelvis. It aims to improve quality of life during treatment.
Chapel Hill, North CarolinaAges 18 years+ - NCT04755699RecruitingEarly Phase 1
Electrical stimulation study for hand or limb movement recovery
This early-stage study tests whether regular, skin-based electrical stimulation can help people with paralysis or weakness regain movement. You would attend frequent clinic sessions for months, while the team checks your ability to follow instructions and your safety.
Manhasset, New YorkAges 18–75 - NCT04750876Recruiting
Psychological and physical therapy follow-up after leg amputation
This trial tests whether adding both psychological support and physical therapy check-ins before and after leg amputation improves recovery and rehab planning. It may help patients feel better and regain function during the transition to rehabilitation care.
La Roche-sur-YonAges 18 years+ - NCT04770571Enrolling by invitation
Study of posterior neck and upper-back spine fixation systems
This trial studies specific surgical hardware used to stabilize the back of the neck and upper back during spine surgery. It may help surgeons compare outcomes for people needing fixation for trauma, instability, failed prior fusion, tumors, or certain degenerative conditions.
Orange, CaliforniaAges 18 years+ - NCT04752774RecruitingPhase 1/Phase 2
Botox-like injection study for arm spasticity after stroke
This trial tests whether IPN10200, a Botox-like treatment, is safe and helps reduce stiff, tight upper-arm muscles caused by spasticity after stroke or brain injury. You may be able to join if you meet specific timing, prior-treatment, and muscle-stiffness measurements.
Downey, CaliforniaAges 18–70 - NCT04715139Recruiting
Testing safety of specific foot and ankle implants
This study follows people who get certain Arthrex foot and ankle implants to check how safely they heal and work over time. It may help your care team by adding long-term information about these devices.
Sacramento, CaliforniaAges 2 years+ - NCT04718168Recruiting
Test of Gore ENFORM patch to reinforce certain hernia repairs
This study looks at whether the Gore ENFORM biomaterial patch helps reinforce the stitch line in specific ventral or hiatal hernia repairs. It will compare outcomes after surgery and follow patients for healing and safety.
San Diego, CaliforniaAges 18 years+ - NCT04678154RecruitingPhase 3
Antibiotic trial for severe open fractures of the leg or foot
This trial tests a new way of giving antibiotics to people with severe open fractures in the leg, ankle, or foot. The goal is to see if it helps prevent infections after surgery.
Redwood City, CaliforniaAges 18–64 - NCT04640727Enrolling by invitation
Surgery comparison for rotated elbow fractures in children
This trial compares two surgical methods for children with a specific type of rotated, fully shifted outer elbow fracture. It aims to find which approach works better for healing and restoring elbow function.
Guangzhou, GuangdongAges 1–18 - NCT04676828Recruiting
SPECT-guided radiation to avoid healthy lung in lung cancer
This study tests a special imaging-guided radiation plan that aims to treat lung cancer while reducing radiation to healthy lung tissue. It may help lower lung side effects while keeping the cancer treatment focused on tumor areas.
Sydney, New South WalesAges 18 years+ - NCT04634383Recruiting
Testing a brain-connected implant to help some blind people see
This early safety study tests an implanted device placed in the brain to help people with very limited sight (no or minimal light). It focuses on whether the implant can be safely used and whether it may support vision-related signals over time.
Chicago, IllinoisAges 19–70 - NCT04650568Enrolling by invitation
Stem cell treatment after ACL ligament surgery
This trial studies whether adding mesenchymal stem cells during ACL (knee ligament) reconstruction helps the knee heal better. You might be eligible if your ACL injury is recent and you’re having a specific type of graft surgery.
Chicago, IllinoisAges 18–60 - NCT04670640Recruiting
Study of brain and therapy factors in trauma-related dissociation
This study looks at how dissociation (feeling detached or unreal) works in people who have had trauma. It tests different “mechanistic” approaches to better understand the brain and how to help, and whether participation can reduce these symptoms.
Atlanta, GeorgiaAges 18–65 - NCT04602806Enrolling by invitation
Precision medicine study for traumatic brain injury
This study is looking at people with traumatic brain injuries to improve how they are treated. If you join, you will get an MRI and other tests within the first two days after your injury, and the researchers will track your recovery over time.
San Francisco, CaliforniaAges 18–65 - NCT04545502Recruiting
Study of aortic grafts and heart patches after aortic surgery
This study looks at how well certain aortic grafts and cardiovascular patches work after surgery. It may help by improving care for people who need these devices, and by collecting safety and outcome information over time.
Aurora, ColoradoAges 18 years+ - NCT04575688Enrolling by invitationPhase 4
Nerve-block injection options for ankle or heel surgery
This trial compares two methods of numbing pain—an injection near the joint versus a nerve block—during ankle or hindfoot surgery. It aims to see which approach helps with comfort and recovery after surgery.
Germantown, TennesseeAges 18–80 - NCT04565366Enrolling by invitation
Study of research care for new spinal cord injuries
This study looks at people after a recent, serious injury—especially a new spinal cord injury—to see how research and clinical knowledge can be improved. Depending on your group (spinal cord injury, other trauma, or healthy), you may be invited to participate if you meet age and injury timing needs.
Fresno, CaliforniaAges 18 years+ - NCT04572256RecruitingEarly Phase 1
Montelukast after ACL surgery to protect knee cartilage
This early trial tests whether montelukast, a tablet used for allergies, can help protect knee cartilage after ACL surgery. It is specifically for people who have a meniscus injury along with their ACL tear.
Lexington, KentuckyAges 25–50
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,016 recruiting trauma studies from the U.S. registry right now, out of 4,936 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.