Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,016 recruiting studies in this area right now.
By phase
- Not applicable2,561
- Phase 2123
- Phase 4112
- Phase 382
- Phase 182
- Phase 1/Phase 234
- Phase 2/Phase 322
Top conditions
- Traumatic Brain Injury151
- Spinal Cord Injuries142
- Spinal Cord Injury105
- Stroke64
- Trauma51
- Mild Traumatic Brain Injury40
- Amputation38
- Anterior Cruciate Ligament Injuries37
- Radiotherapy Side Effect37
- Hip Fractures36
- Rotator Cuff Tears35
- Spinal Cord Injuries (SCI)34
- Burns28
- Carpal Tunnel Syndrome28
- Anterior Cruciate Ligament Rupture27
- Cardiotoxicity26
- Carpal Tunnel Syndrome (CTS)26
- Breast Cancer25
Leading sponsors
- VA Office of Research and Development34
- Cairo University22
- Kessler Foundation20
- Johns Hopkins University19
- University of Miami19
- Zimmer Biomet19
- University of Florida18
- University of British Columbia17
- Mayo Clinic16
- Riphah International University16
Where studies are running
- California159
- Texas91
- Florida79
- New York78
- Illinois57
- Massachusetts55
- Pennsylvania51
- Minnesota45
- Ohio43
- Colorado41
Recruiting studies3,016 total
- NCT04572256RecruitingEarly Phase 1
Montelukast after ACL surgery to protect knee cartilage
This early trial tests whether montelukast, a tablet used for allergies, can help protect knee cartilage after ACL surgery. It is specifically for people who have a meniscus injury along with their ACL tear.
Lexington, KentuckyAges 25–50 - NCT04536103Recruiting
Accelerated MRI scans after ACL knee injury surgery
This trial tests a faster MRI scan method to measure healing in the knee after an ACL (anterior cruciate ligament) tear and reconstruction. It may help researchers compare scan quality while participants go through standard rehab.
Cleveland, OhioAges 18–50 - NCT04496609Recruiting
Testing a spinal stimulation treatment for incomplete spinal cord injury
This trial studies whether a spinal cord stimulation approach plus rehab can improve function and safety in people with an incomplete spinal cord injury who cannot walk. It may help people by supporting rehabilitation over time, but it requires surgery and specific health and imaging conditions.
GarchesAges 18–65 - NCT04550377RecruitingPhase 2
Cannabidiol for PTSD, including PTSD after mild head injury
This Phase 2 study tests whether cannabidiol (CBD) can reduce PTSD symptoms, including in people who also had a mild traumatic brain injury (TBI). It’s meant to see if CBD is helpful and safe for PTSD symptoms over the study period.
New York, New YorkAges 18–70 - NCT04521881RecruitingPhase 3
Testing an antifibrinolytic for mild head injury in older adults
This study tests whether an anti-bleeding medicine (given to reduce unwanted clot breakdown) can improve outcomes after a mild head injury in people 50 and older. It is looking for patients who arrive quickly after injury and have certain symptoms like brief loss of consciousness, confusion, or nausea.
London, LondonAges 50 years+ - NCT04523415Recruiting
CT-based study of displaced upper arm bone fractures
This trial is studying people age 17+ with a recently fractured upper arm bone near the shoulder, using CT scans and 3D planning. It may help doctors improve how these fractures are evaluated and treated after injury.
Shijiazhuang, HebeiAges 17 years+ - NCT04589819Enrolling by invitationPhase 4
Teriparatide for tibia stress fracture recovery for duty
This trial tests teriparatide, a medication that helps build bone, to see if it can speed recovery and help certain enlisted Army members return to training duty after a tibia bone injury. You may be asked to self-administer the medication while you recover and take part in study follow-ups.
Columbia, South CarolinaAges Any age - NCT04533152Recruiting
Study risk factors for healing in diabetic foot ulcers
This study looks at what factors affect outcomes in adults with diabetic foot ulcers. It may help doctors better predict healing and complications by better understanding what influences progress.
CaenAges 18 years+ - NCT04554212Recruiting
Blood flow restriction therapy after kneecap instability
This trial tests whether a special exercise method called blood flow restriction training can help people recover faster and get back to running and pivoting activities after a kneecap (patella) that slips out of place. It may help strengthen the knee while you go through physical therapy.
Lexington, KentuckyAges 14–40 - NCT03096197Recruiting
Exoskeleton and spinal stimulation for long-term spinal cord injury
This trial tests whether an external walking-assist device (an exoskeleton) plus targeted spinal cord stimulation can help people with long-term spinal cord injury. It may be designed for wheelchair users who meet specific nerve function and bone health requirements.
West Orange, New JerseyAges 18–65 - NCT04229966Recruiting
Study of real-world treatment for acute epidural bleeding after injury
This observational study looks at how doctors treat an acute epidural hematoma in large head-injury surgeries as they would in routine care. It may help improve understanding of which real-world treatment choices lead to better outcomes.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT04437498Recruiting
Vagus nerve stimulation for veterans with mild brain injury and PTSD
This study looks at whether stimulating the vagus nerve can improve symptoms in veterans who have mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD). If you qualify, you may be offered a device-based treatment and monitored for safety and symptom changes.
Decatur, GeorgiaAges 18–55 - NCT04441983Recruiting
High-resolution foot MRI trial for patients and volunteers
This trial uses a powerful 7T MRI scanner to get detailed images of the foot and extremities. It includes patients with specific conditions (like Morton neuroma or tendon tears) and healthy volunteers, aiming to understand normal and diseased tissue better.
Zurich, Canton of ZurichAges 18 years+ - NCT04445649Recruiting
Find factors to help people regain consciousness after brain injury
This study looks at what predicts recovery of consciousness after certain serious brain injuries, such as stroke or traumatic brain injury. It may help clinicians better identify which patients are more likely to wake up and guide early rehabilitation and care.
Hessisch OldendorfAges 18–85 - NCT04429217Recruiting
Immediate versus delayed weight-bearing after ankle surgery
This trial compares two rehab plans after ankle fracture surgery: putting weight on the ankle right away versus waiting. It aims to see which approach is safer and better for healing and recovery.
LuganoAges 18–70 - NCT04485286RecruitingPhase 2
PET scan tracer to find lung or pancreas radiation injury
This Phase 2 study tests a special PET scan tracer to help doctors spot tissue damage after radiation treatment in people with certain lung or pancreatic cancers. The goal is to improve detection and planning around chemoradiation and surgery.
Boston, MassachusettsAges 18–80 - NCT04403074Recruiting
Procedure for pancreas pain in chronic pancreatitis
This trial tests an endoscopy-based procedure called celiac plexus neurolysis to reduce pain from chronic pancreatitis. It may help people whose pancreas pain has not been adequately controlled with other treatments.
Indianapolis, IndianaAges 18 years+ - NCT04389749Recruiting
Continuous passive motion after certain hip or leg fractures
This trial studies whether a device that gently moves your leg helps recovery after surgery for specific hip or knee fractures. It may help with healing and getting you back to moving more comfortably sooner, compared with not using the device.
Cincinnati, OhioAges 18 years+ - NCT04400266RecruitingPhase 4
Buspirone and melatonin for depression after a brain injury
This trial studies whether the medicines buspirone and melatonin can reduce depression symptoms in people who had a mild or moderate traumatic brain injury (TBI) at least 3 months ago. It may help if you have ongoing depression after TBI and can safely take study medications and attend regular visits, including MRI scans.
Boston, MassachusettsAges 18–64 - NCT04454203RecruitingPhase 4
Local anesthetic catheter to reduce tourniquet-related blood pressure spikes
This Phase 4 trial tests whether a local anesthetic catheter placed near a nerve and artery can prevent high blood pressure caused by a tourniquet during total ankle replacement surgery. If it works, it may make recovery safer and more comfortable for some patients.
Durham, North CarolinaAges 18–75 - NCT02577731Recruiting
Study of bone marrow changes after major injury or elective hip surgery
This trial studies how bone marrow and blood-making cells may behave after severe trauma or after elective (planned) hip surgery. It may help researchers understand why recovery can be harder in some people and guide better care.
Gainesville, FloridaAges 18 years+ - NCT04264065Recruiting
Albumin study in severe burn patients in ICU
This trial looks at whether giving or measuring albumin (a blood protein) can help predict outcomes for people with very severe burns in the ICU. It may help doctors understand who is at higher risk and guide care during the first day after injury.
Paris, FranceAges 18–80 - NCT04299022Recruiting
Study of ViviGen bone graft for fracture healing
This study follows people who are treated with a bone graft called ViviGen to help heal fractures, delayed healing, or non-healing (“non-union”) bone problems. The goal is to check how safe it is and how well it works in real-world orthopaedic care.
Orlando, FloridaAges Any age - NCT04269447Enrolling by invitation
Collecting samples from people with abdominal aortic aneurysm
This study sets up a long-term biobank by collecting health information and tissue/blood samples from people with an abdominal aortic aneurysm. It may help doctors better understand what causes aneurysms and how to detect or treat them in the future.
Solna, Stockholm CountyAges 50–80
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,016 recruiting trauma studies from the U.S. registry right now, out of 4,936 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.