Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,219 recruiting studies in this area right now.
By phase
- Not applicable2,751
- Phase 2121
- Phase 4117
- Phase 187
- Phase 384
- Phase 1/Phase 237
- Phase 2/Phase 322
Top conditions
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Spinal Cord Injury100
- Trauma60
- Stroke56
- Anterior Cruciate Ligament Injuries44
- Amputation43
- Mild Traumatic Brain Injury41
- Hip Fractures40
- Rotator Cuff Tears40
- Radiotherapy Side Effect36
- Spinal Cord Injuries (SCI)35
- Carpal Tunnel Syndrome34
- Burns31
- Anterior Cruciate Ligament Rupture30
- Breast Cancer29
- Cardiotoxicity29
- Carpal Tunnel Syndrome (CTS)25
Leading sponsors
- VA Office of Research and Development37
- Cairo University36
- Riphah International University32
- Kessler Foundation21
- University of Miami21
- Johns Hopkins University20
- Sohag University19
- Mayo Clinic18
- Peking University Third Hospital18
- University of Texas Southwestern Medical Center18
Where studies are running
- California167
- Texas101
- New York85
- Florida80
- Illinois57
- Massachusetts57
- Pennsylvania52
- Ohio51
- Minnesota46
- Maryland42
Recruiting studies3,219 total
- NCT05626816Recruiting
Genital nerve stimulation to improve bowel control after spinal injury
This trial studies whether stimulating nerves near the genitals (a gentle electrical stimulation approach) can improve bowel function in people with spinal cord injury. It may help bowel control when bowel dysfunction is caused by nerve injury.
Cleveland, OhioAges 18 years+ - NCT05627908Recruiting
PseAn study for adults with certain organ injuries
This trial is for adults who have had a CT-confirmed injury to the spleen, liver, and/or kidney from blunt or penetrating trauma. The goal is to study this type of injury and compare how patients do after treatment.
Milan, ItaliaAges 18 years+ - NCT05634109RecruitingPhase 3
Whole blood to treat adults with severe bleeding trauma
This trial compares giving whole blood versus standard care in adults with severe trauma and dangerous blood loss (hemorrhagic shock). The goal is to see if whole blood helps stabilize patients faster and improves outcomes after major bleeding.
Cali, Valle del Cauca DepartmentAges 18 years+ - NCT05635929Recruiting
Topical treatment to reduce mouth sores during or after radiation
This study tests a new cream/gel applied to the mouth to lower the chance of severe mouth sores in people receiving radiation for head and neck cancer. It also looks at how treatment affects quality of life using patient questionnaires.
Madrid, MadridAges 18 years+ - NCT05637294Recruiting
Compare night-only versus full-time splinting for carpal tunnel
This study looks at whether wearing a wrist splint only at night works as well as wearing it full-time for carpal tunnel syndrome (CTS). It may help you find the most helpful and practical splint schedule to reduce symptoms.
HelsinkiAges 18 years+ - NCT05638360RecruitingPhase 2
Test medicine for healing after wrist bone fracture surgery
This Phase 2 trial studies whether Ru-Yi-Jin-Huang-Saan (a traditional Chinese medicine) helps the wrist heal better after surgery for a Colles’ fracture. If you qualify, you may receive the medicine and be asked to complete questionnaires to track healing and outcomes.
Changhua, ChanghuaAges 20–80 - NCT05638191Recruiting
Nerve transfer surgery for arm grasp after neck spinal cord injury
This study looks at whether nerve transfer surgery can help restore hand grasp function after a neck (cervical) spinal cord injury. You may be eligible if your injury is recent and you meet specific strength patterns and can commit to rehabilitation after surgery.
Vancouver, British ColumbiaAges 18–70 - NCT05638581RecruitingPhase 3
Compare low-titer type O whole blood for trauma bleeding
This study tests whether giving low-titer type O whole blood (or related blood products) works better for treating serious bleeding after a traumatic injury. It’s for adults who start blood transfusions right away under a massive bleeding plan.
Birmingham, AlabamaAges 15 years+ - NCT05641441Recruiting
Study hearing side effects after targeted treatment for vestibular schwannoma
This study looks at how targeted brain/skull-base treatment for a vestibular schwannoma may affect hearing (ear “ototoxicity,” meaning damage to hearing). It may help doctors better predict and prevent hearing problems in people treated for this tumor.
GenevaAges 18 years+ - NCT05642026RecruitingPhase 4
Continuous nerve block for pain from multiple broken ribs
This study tests a continuous nerve block—a numbing medicine delivered near the nerves—to reduce pain from rib fractures. It may help people with two or more broken ribs manage pain more effectively while recovering.
Lexington, KentuckyAges 18 years+ - NCT05642832Recruiting
Test a breathing-device method to reduce breathing effort
This trial checks whether a special “through-flow” system can safely reduce how hard your body has to breathe when you are on a breathing machine. It is mainly a feasibility study, meaning the focus is on whether the approach can be done safely and effectively.
Toronto, OntarioAges 18 years+ - NCT05644171Recruiting
Epidural spinal stimulation for chronic spinal cord injury recovery
This trial tests whether a stimulating device placed near the spinal cord can help improve movement and rehabilitative function in people with long-term spinal cord injuries. It may help some patients strengthen function, but only if they meet specific injury and health requirements.
SingaporeAges 21 years+ - NCT05644522Recruiting
At-home brace study for leg support and walking
This study tests an at-home wearable activity monitor and brace-related walking support for people who already use a knee-ankle-foot brace. It may help researchers understand how brace use and day-to-day movement relate to walking ability.
Chicago, IllinoisAges 18–89 - NCT05645003Recruiting
Brain stimulation therapy for nerve pain after spinal cord injury
This trial tests whether painless magnetic stimulation of the brain (non-surgical) can reduce long-lasting nerve pain after spinal cord injury. It may help people whose spinal cord injury-related pain has been present for at least six months.
AfyonkarahisarAges 20–70 - NCT05647044RecruitingPhase 1
Brain stimulation to reduce impulsivity and suicidal thoughts after mild TBI
This early-stage study tests whether a noninvasive brain stimulation treatment (called iTBS) can reduce impulsivity and suicidal thoughts in Veterans who have had a mild traumatic brain injury (mTBI) and recent suicidal thinking. If you qualify, you may be offered a monitored treatment plan and assessments for safety and symptom changes.
Hines, IllinoisAges 22–65 - NCT05647135Recruiting
High-protein tube feeds for multiple trauma ICU patients
This trial studies whether very high protein tube-feeding helps critically ill adults with multiple injuries recover better in the ICU. It compares feeding approaches during the time you need breathing support.
BucharestAges 18 years+ - NCT05649904Recruiting
Study for adults needing brain fluid drainage after brain bleeding or infection
This study looks at patients age 18+ who need a procedure to drain brain fluid after certain brain bleeds (like intraventricular or subarachnoid bleeding, or chronic subdural bleeding) or after ventriculitis. It aims to better understand and improve care for people with these serious conditions.
Columbus, OhioAges 18 years+ - NCT05650996RecruitingPhase 1
Early hand therapy participation after broken wrist
This Phase 1 study looks at whether starting hand activity soon after a distal radius fracture helps improve recovery outcomes. You may be able to join if your broken wrist is treated with a cast and you can report your symptoms and function reliably in English.
Washington, VirginiaAges 18 years+ - NCT05655156Recruiting
Study of a pig-tissue implant for serious knee ligament injuries
This trial studies an implant made from pig tissue for people with multiple injured knee ligaments. It aims to see how well the implant works and whether people can safely follow the required rehabilitation plan.
Stoke-on-TrentAges 18 years+ - NCT05657899Recruiting
Olecranon fracture surgery with or without K-wires
This trial studies whether using small metal K-wires during surgery for certain elbow (olecranon) fractures improves outcomes compared with not using them. You may be eligible if your injury matches the trial’s fracture type and surgery timing, and you can attend follow-up visits and answer questionnaires.
Lund, Skåne CountyAges 18 years+ - NCT05658289Recruiting
Latarjet vs shoulder bone surgery after front dislocation
This trial compares two types of surgery that rebuild the front (anterior) shoulder bone when there has been significant bone loss. It may help find which operation works better to keep your shoulder from dislocating again.
Halifax, Nova ScotiaAges 16–40 - NCT05660603Recruiting
Nerve blocks for hip fracture surgery pain control
This trial compares two different pain-control methods (two types of nerve blocks) during hip fracture surgery under general anesthesia. The goal is to see which approach works better and is safer for pain relief after surgery.
Zagazig, AlsharqiaAges 60 years+ - NCT05668182Recruiting
TRUMATCH graft cage for broken thigh/leg/arm bone gaps
This study looks at how well a specific metal implant (the TRUMATCH graft cage) works when there is a missing segment of a long bone in the arm, thigh, or shin. It may help stabilize the bone while doctors rebuild the defect with standard surgical care.
San Diego, CaliforniaAges 18 years+ - NCT05670288Recruiting
Studying how gut bacteria affect digestion after spinal cord injury
This study looks at how changes in gut bacteria may affect bowel function and metabolism during the first year after a spinal cord injury. You may be asked about bowel symptoms and other factors, and your results may help guide future care for digestion problems after injury.
Birmingham, AlabamaAges 18–85
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,219 recruiting trauma studies from the U.S. registry right now, out of 5,138 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.