Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,391 recruiting studies in this area right now.
By phase
- Not applicable2,721
- Phase 2568
- Phase 1363
- Phase 3265
- Phase 1/Phase 2227
- Phase 4192
- Phase 2/Phase 355
Top conditions
- Prostate Cancer645
- Bladder Cancer186
- Acute Kidney Injury134
- Chronic Kidney Diseases122
- Chronic Kidney Disease107
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence60
- Kidney Cancer59
- Colorectal Cancer58
- Ovarian Cancer56
- Lung Cancer51
- Cancer48
- Lupus Nephritis48
- Melanoma47
- Head and Neck Cancer46
- Metastatic Prostate Cancer46
- Hypertension45
Leading sponsors
- Mayo Clinic64
- National Cancer Institute (NCI)48
- Peking University First Hospital39
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong35
- Novartis Pharmaceuticals33
- AstraZeneca29
- IRCCS Azienda Ospedaliero-Universitaria di Bologna29
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris27
Where studies are running
- California358
- Arizona109
- Alabama107
- New York96
- Florida93
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Minnesota50
Recruiting studies4,391 total
- NCT06084338RecruitingPhase 2
Focused Radiation Therapy Without Hormone Therapy for Advanced Prostate Cancer
This trial tests whether giving focused radiation to many cancer spots (SBRT) can work without using testosterone-blocking hormone therapy. It is for men whose prostate cancer has spread and is no longer responding to low testosterone, and who have already tried one of the newer hormone drugs.
West Los Angeles, CaliforniaAges 18 years+ - NCT06101745RecruitingPhase 2/Phase 3
Trial to see ureters during abdominal or pelvic surgery
This trial tests a dye called Nizaracianine Triflutate that helps surgeons see the ureters (tubes from kidneys to bladder) during surgery. It aims to make surgery safer by reducing the risk of accidentally injuring the ureters.
Los Angeles, CaliforniaAges 18 years+ - NCT06085846Enrolling by invitation
Real-world study of the Vivally system
This study tracks patients who are using the Vivally system in real life, a device that may help with bladder control. It aims to learn how well the device works outside of a clinic.
Columbus, OhioAges 18 years+ - NCT06095089RecruitingPhase 1
Study of two drugs for advanced prostate cancer
This trial tests a new combination of two study drugs for people with advanced prostate cancer that has spread or is no longer responding to hormone therapy. The goal is to see if the combination is safe and works against the cancer.
Aurora, ColoradoAges 18 years+ - NCT06091566Recruiting
Nerve stimulation device for overactive bladder and bowel
This study tests a new kind of nerve stimulation device that is inserted into the vagina to help control bladder and bowel problems. It may reduce urgent trips to the bathroom, leaking, and other symptoms of overactive bladder or bowel dysfunction.
AarhusAges 18 years+ - NCT06096142Recruiting
A drug-coated stent for dialysis access narrowing
This trial tests a new covered stent that slowly releases a drug to keep the dialysis access (a surgically created blood vessel) open. It is designed for people whose access is narrowed or blocked and needs a procedure to restore blood flow and allow dialysis to continue.
Salvador, Estado de BahiaAges 18 years+ - NCT06085183RecruitingPhase 4
Study of a dye to check ureters during surgery in people with kidney problems
This trial tests a blue dye (Bludigo) to help doctors see if the ureters are open during surgery. It is for people with normal or reduced kidney function who need a procedure where the ureters are checked.
Albany, New YorkAges 18–85 - NCT04885179Recruiting
Study of SPLIS genetics and patient experiences
This observational study and patient registry collects information from people diagnosed with SPLIS due to specific changes in the SGPL1 gene, including children and newborns. It helps researchers understand the condition better and may improve future care and research planning.
San Francisco, CaliforniaAges Any age - NCT05919329RecruitingPhase 4
PSMA scan changes after starting hormone therapy for prostate cancer
This study looks at how a prostate-specific scan marker (PSMA) changes after you start or continue hormone therapy. It may help doctors better understand who responds and how quickly prostate cancer biology shifts during treatment.
Portland, OregonAges 18 years+ - NCT06096597RecruitingPhase 2/Phase 3
Amniotic Membrane Therapy for Bladder Pain
This trial tests a treatment made from amniotic membrane (a natural tissue) to help reduce pain and discomfort in people with Interstitial Cystitis (also called Painful Bladder Syndrome). It is for women who have tried at least one other treatment without success.
Clevleand, OhioAges 18 years+ - NCT06085729RecruitingPhase 1/Phase 2
Study of ADI-PEG20 with chemo for aggressive prostate cancer
This study tests a combination of three drugs—ADI-PEG20, carboplatin, and cabazitaxel—in men with aggressive variant prostate cancer that has stopped responding to hormone therapy. The goal is to see if this combination can shrink or slow the cancer.
Houston, TexasAges 18 years+ - NCT06083051Recruiting
Comparing symptoms from different ureteral stents after stone surgery
This study compares four types of ureteral stents to see which causes the fewest side effects after kidney stone treatment. If you have a stent placed after stone surgery, your symptoms will be tracked to help find the best option.
Madison, WisconsinAges 18–89 - NCT06089473Recruiting
Home Exercise Program for Frail Kidney Transplant Candidates
This study tests whether a 12-week home exercise program (supervised by video calls) can help people who are frail feel stronger and healthier before a kidney transplant. You'll do exercises at home and connect with a trainer online.
Montreal, QuebecAges 18 years+ - NCT06101290Recruiting
Local therapy for progressing spots in genitourinary cancers
This trial explores whether treating only the new or growing spots of cancer (called oligoprogression) with local therapies like radiation or ablation can help you stay on your current systemic treatment longer. It is for people with prostate, bladder, or kidney cancer that has started to progress in a few places.
Sacramento, CaliforniaAges 18 years+ - NCT06100705RecruitingPhase 2
Immunotherapy plus testosterone for advanced prostate cancer
This study combines an immunotherapy drug called sipuleucel-T (which boosts your immune system to fight cancer) with a high-dose testosterone treatment called bipolar androgen therapy. The goal is to see if this combination can help men with advanced prostate cancer that is not responding to usual hormone therapy.
New Haven, ConnecticutAges 18 years+ - NCT06099093RecruitingPhase 4
PSMA PET scan before standard therapy for advanced prostate cancer
This trial will test if a special PET scan (18F-DCFPyL) can help doctors plan your treatment with a radioactive medicine called 177Lu-vipivotide tetraxetan. You are eligible if you already qualify for that standard therapy and have had a prior PSMA PET scan showing at least one active cancer site.
Boston, MassachusettsAges 18 years+ - NCT06095440Recruiting
A study on treatment results for hepatorenal syndrome
This study looks back at medical records of people who had hepatorenal syndrome (a type of kidney failure linked to liver disease) while in the hospital. The goal is to understand what treatments were used and how well patients did, which might help guide future care.
Dallas, TexasAges 18–85 - NCT06085664RecruitingPhase 1/Phase 2
Immunotherapy before prostate cancer surgery
This trial tests a new immunotherapy drug (REGN5678) given before surgery to men with high-risk prostate cancer that hasn't spread. The goal is to see if the drug can shrink or control the cancer before the prostate is removed.
Houston, TexasAges 18 years+ - NCT06091124RecruitingPhase 2
Immunotherapy plus chemo before surgery for neuroendocrine bladder cancer
This trial tests a combination of an immunotherapy drug (adebrelimab) with two chemotherapy drugs (etoposide and cisplatin) given before surgery for a rare, aggressive type of bladder cancer called neuroendocrine carcinoma. The goal is to see if this approach can shrink the tumor and improve outcomes.
Nanjing, JiangsuAges 18–75 - NCT06090227RecruitingPhase 1/Phase 2
Metformin for FSGS: A phase 1/2 trial
This trial tests whether the diabetes drug metformin can help people with a kidney disease called FSGS, by activating a cell-protecting pathway. Participants will take metformin or a placebo along with their usual steroid treatment.
New Haven, ConnecticutAges 18–80 - NCT06094543Recruiting
Improving access and adherence for overactive bladder treatment
This study compares two ways to help women with overactive bladder get treatment and stick with it. You might be able to join if you are a woman with ongoing OAB symptoms and haven't had certain treatments recently.
Redwood City, CaliforniaAges 18 years+ - NCT03452774Recruiting
AI matches your cancer tests to possible treatment trials
This trial uses an AI system to help match people with certain cancer types and specific tumor test results (like gene or protein markers) to relevant clinical trials. It may help you and your doctor find studies that fit your cancer biology faster.
Birmingham, AlabamaAges Any age - NCT04288427Recruiting
Testing a prostate marker to predict response to finasteride
This study looks at a prostate test marker to understand who is more likely to benefit from 5-ARI medicines such as finasteride or dutasteride. If you have enlarged prostate symptoms and are getting a biopsy, the results may help doctors better choose or interpret 5-ARI treatment.
Boston, MassachusettsAges 50 years+ - NCT05490225Recruiting
Test device to make dialysis fistulas easier to stick safely
This trial tests a small implant device that can make dialysis fistulas easier to access with needles when normal needle access is too difficult or risky. It may help reduce painful failed attempts and needle-related complications for people with certain types of fistulas.
Dothan, AlabamaAges 18 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,391 recruiting nephrology & urology studies from the U.S. registry right now, out of 6,874 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.