Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,391 recruiting studies in this area right now.
By phase
- Not applicable2,721
- Phase 2568
- Phase 1363
- Phase 3265
- Phase 1/Phase 2227
- Phase 4192
- Phase 2/Phase 355
Top conditions
- Prostate Cancer645
- Bladder Cancer186
- Acute Kidney Injury134
- Chronic Kidney Diseases122
- Chronic Kidney Disease107
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence60
- Kidney Cancer59
- Colorectal Cancer58
- Ovarian Cancer56
- Lung Cancer51
- Cancer48
- Lupus Nephritis48
- Melanoma47
- Head and Neck Cancer46
- Metastatic Prostate Cancer46
- Hypertension45
Leading sponsors
- Mayo Clinic64
- National Cancer Institute (NCI)48
- Peking University First Hospital39
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong35
- Novartis Pharmaceuticals33
- AstraZeneca29
- IRCCS Azienda Ospedaliero-Universitaria di Bologna29
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris27
Where studies are running
- California358
- Arizona109
- Alabama107
- New York96
- Florida93
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Minnesota50
Recruiting studies4,391 total
- NCT05525507RecruitingPhase 1
Test early immune-tolerance treatment for matched kidney transplant patients
This Phase 1 study tests a treatment plan given after a kidney transplant to help the immune system stay calm and reduce the risk of rejection. Participants must have a well-functioning kidney transplant from a closely matched living donor and meet health and safety requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT05842239Recruiting
Hyperbaric oxygen therapy for low sperm count infertility
This trial tests whether breathing 100% oxygen in a pressurized chamber (hyperbaric oxygen therapy) can improve fertility in men who have an unexplained low sperm count. It may help by improving sperm health, but you would need multiple sperm tests and to be able to follow the clinic schedule.
ẔerifinAges 21 years+ - NCT05847166Recruiting
Testing a PSMA-targeted treatment for prostate cancer
This trial studies a treatment that targets a protein called PSMA in people with prostate cancer. It may help shrink or control the cancer and is being tested in different risk groups and stages of disease.
Bydgoszcz, PolandAges 18 years+ - NCT05846581Recruiting
Dialysis graft registry for adults getting a new vascular graft
This registry follows adults with kidney failure who need a dialysis access connection in the arm using the GORE ACUSEAL graft. It helps track outcomes and safety over time while you receive standard dialysis care.
BielefeldAges 18 years+ - NCT05826990RecruitingPhase 2
IV antibiotic study for children with complex urinary tract infections
This study tests a new IV antibiotic combination (cefepime-enmetazobactam) for children with complicated urinary tract infections or kidney infections. The goal is to see how well it works and if it is safe.
Hradec KrálovéAges Up to 18 years - NCT05326399Recruiting
Kidney biopsies after liver transplant for new kidney problems
This trial studies kidney biopsies in people who had a liver transplant and then developed new signs of kidney damage. The goal is to better understand what’s causing the problem and how to guide next steps.
ShanghaiAges 18–75 - NCT05822609RecruitingPhase 2
Semaglutide for kidney disease in adults with type 1 diabetes
This Phase 2 study tests semaglutide (a diabetes and weight-related medicine) to see if it can slow or improve diabetic kidney disease in people with type 1 diabetes. You may be able to join if you have type 1 diabetes for at least 5 years and ongoing signs of kidney damage measured in urine tests.
Aurora, ColoradoAges 18 years+ - NCT05837806RecruitingPhase 2
Tislelizumab and disitamab as pre-surgery treatment for HER2 UTUC
This trial tests whether giving tislelizumab plus disitamab vedotin before surgery (neoadjuvant therapy) can improve outcomes for people with HER2-positive, high-risk upper tract urothelial cancer. It also looks at the treatment’s safety and helps doctors learn if certain tumor features predict response.
TianjinAges 18 years+ - NCT05832268Enrolling by invitation
Pelvic floor recovery after childbirth anal sphincter injury
This study looks at how the pelvic floor (the support muscles and tissues) works in people who had a specific anal sphincter injury during vaginal birth, compared with people who had uncomplicated vaginal deliveries. It may help doctors better understand recovery and function after childbirth injuries.
OsloAges 18 years+ - NCT05833867RecruitingPhase 1
Bladder cancer trial combining radiation and Sacituzumab
This Phase 1 study tests whether a new bladder-cancer treatment plan—radiation given at the same time as sacituzumab govitecan—can help people with muscle-invasive bladder cancer without starting with traditional chemo/radiation. Because it’s early-stage, the main goal is safety and learning the best way to use this combination to preserve the bladder.
Cleveland, OhioAges 18 years+ - NCT05830058RecruitingPhase 2
PET-guided focused radiation for limited worsening lung, melanoma, kidney cancer
This Phase 2 study tests whether using a PET scan to guide focused radiation (SBRT) can control a small number of cancer spots that are starting to grow despite prior treatment. It may help patients avoid wider radiation by targeting only the limited progressing areas.
Duarte, CaliforniaAges 18 years+ - NCT05834777RecruitingPhase 3
Prevent low blood pressure during dialysis by blocking bradykinin
This Phase 3 trial tests a medicine that blocks a body signal (bradykinin) to help prevent dangerous drops in blood pressure during hemodialysis. If you often get “intradialytic hypotension,” this study may help you dialyze more safely.
Nashville, TennesseeAges 18–80 - NCT05840484Recruiting
Monitoring study for men on active surveillance
This trial follows men with prostate cancer who choose “active surveillance” instead of immediate treatment. It tests whether careful tracking (including patient reports) can help manage cancer over time and guide decision-making.
Houston, TexasAges 18 years+ - NCT05834803Recruiting
Stenting narrowed kidney artery to help high-risk patients
This trial studies whether placing a small stent in a severely narrowed kidney artery can improve outcomes for people with high-risk, artery-hardening kidney blood-flow problems. It focuses on people whose high blood pressure or kidney function has been getting worse despite multiple medications.
Aarhus NAges 18 years+ - NCT05837767Recruiting
Radiation study for tumors that spread to soft tissue areas
This study looks at how a planned form of palliative radiation therapy treats certain solid cancers that have spread outside the brain to larger soft-tissue areas. It may help shrink tumors and relieve symptoms, but it also asks you to meet specific safety and treatment-timing rules.
Basking Ridge, New JerseyAges 18 years+ - NCT05817539Recruiting
Early circulation-focused care during kidney dialysis in ICU
This trial looks at whether starting dialysis-related care early, aimed at improving blood flow to tissues, can help people in the ICU who have sudden kidney failure. It may help reduce problems related to poor tissue circulation, but it is very specific about ICU illness and current treatments.
AjaccioAges 18 years+ - NCT05836922Recruiting
Checking kidney oxygen after lung transplant to predict kidney injury
This pilot study looks at whether a painless skin sensor can measure kidney oxygen levels after lung transplant surgery. The goal is to predict and possibly prevent postoperative kidney failure by identifying risk early.
MarseilleAges 18 years+ - NCT05825950Recruiting
AI tool for predicting outcomes in bladder cancer
This trial tests an artificial-intelligence (AI) tool that uses your bladder cancer details to help predict outcomes. It may help doctors better choose the next treatment after bladder cancer is found early (non-muscle invasive).
Dallas, TexasAges 18–99 - NCT05842044RecruitingPhase 2
NSAID pain medicine after robotic kidney-sparing surgery
This Phase 2 study looks at whether taking an anti-inflammatory pain medicine (an NSAID) after robotic partial nephrectomy is safe and helpful. It may reduce pain while checking for stomach, bleeding, and heart-related side effects after kidney-sparing surgery.
Miami, FloridaAges 18–99 - NCT05828823Recruiting
Two-times-a-week dialysis for new patients
This study tests whether starting dialysis at twice a week, instead of the usual three times, is safe and effective for people who still have some kidney function. If the kidneys still make urine and clear waste, being on dialysis less often may maintain that function longer.
Jacksonville, FloridaAges 18 years+ - NCT05814146Recruiting
Testing a dialysis fluid change for kidney failure
This trial studies whether using a dialysis fluid with a different bicarbonate level can help people with long-term kidney failure treated with regular hemodialysis. If you qualify, you may be assigned to receive a specific bicarbonate concentration during your dialysis sessions.
Boston, MassachusettsAges 18–120 - NCT05838716RecruitingPhase 3
Vitamin D During Hormone Therapy for Prostate Cancer
This trial studies whether taking vitamin D while you are on prostate hormone therapy (ADT) affects your health outcomes. It may help by keeping vitamin D levels in a safe range during treatment.
Newark, DelawareAges 50 years+ - NCT05806515RecruitingPhase 2
Carboplatin before surgery for high-risk BRCA prostate cancer
This trial tests giving the chemotherapy drug carboplatin before surgery to treat people with high-risk prostate cancer and an inherited BRCA1 or BRCA2 gene change. The goal is to shrink or control the cancer before an operation and improve outcomes.
Anchorage, AlaskaAges 18 years+ - NCT05796375RecruitingPhase 2
Urine testing instead of repeat bladder scope checks
This Phase 2 study tests whether urine tests can help monitor “non-muscle-invasive” bladder cancer without doing as many invasive bladder scopes (cystoscopies). If you qualify, you may be able to replace some scope visits with urine sample testing while still keeping close watch for cancer coming back.
West Haven, ConnecticutAges 18 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,391 recruiting nephrology & urology studies from the U.S. registry right now, out of 6,874 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.