Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT07537478Recruiting
Breathing measurement study using CO2 and lung function tests
This study measures how you breathe using two methods: tracking carbon dioxide in your breath and measuring lung function with a spirometer (a breathing device). Boston Scientific is testing these measurement approaches to understand how well they work together.
Saint Paul, MinnesotaAges 18 years+ - NCT06559150RecruitingPhase 2
Study of ensifentrine for non-cystic fibrosis bronchiectasis
This trial tests an inhaled drug called ensifentrine in people with bronchiectasis (damaged, widened airways in the lungs). The goal is to see if it can reduce flare-ups and improve symptoms.
Birmingham, AlabamaAges 18–80 - NCT07203287RecruitingPhase 4
Comparing muscle relaxants in kidney disease patients during surgery
This trial compares two muscle relaxants, rocuronium and cisatracurium, to see which causes fewer complications in people with chronic kidney disease (not on dialysis) who need general anesthesia. If you have kidney disease and are having surgery that requires a breathing tube, this study may help determine the safer drug for you.
Galveston, TexasAges 18–80 - NCT06815198Recruiting
Ultrasound to measure air speed from lungs
This study uses a special ultrasound (pulsed echo Doppler) to measure how fast air moves out of your lungs during a breathing test. It aims to understand lung function better, which may help people with certain lung conditions.
BolognaAges 18 years+ - NCT07082179RecruitingPhase 2
Immunotherapy plus chemotherapy for stage III lung cancer
This trial tests combining immunotherapy with chemotherapy for people with stage III non-small cell lung cancer that cannot be removed by surgery. It aims to see if this combination can shrink the tumor and improve outcomes.
NanjingAges 18–75 - NCT07205952Recruiting
Detecting breathing difficulty in ventilated patients
This study looks at whether a computer system can automatically detect when a patient on a breathing machine (ventilator) is having trouble breathing. It may help doctors respond faster to the patient's needs.
Buenos Aires, Buenos AiresAges Any age - NCT06821451Recruiting
Robot-guided dye marking for lung nodule surgery
This trial tests a new way to find and remove small lung nodules using a robot-guided camera to mark the nodule with dye, then a video-assisted surgery to remove it. It may help patients whose nodules are hard to locate during surgery.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06875076RecruitingPhase 2
Ivonescimab plus chemotherapy for pretreated mesothelioma
This trial is testing a new immunotherapy drug (ivonescimab) combined with chemotherapy for people with mesothelioma that has already been treated. It aims to see if this combination can shrink tumors or slow the disease.
Changchun, JilinAges 1.5 years–6.3 years - NCT05815173RecruitingPhase 1
Ladarixin plus sotorasib for KRAS-mutated lung cancer
This Phase 1 trial tests whether ladarixin combined with sotorasib can help people with advanced or metastatic non-small cell lung cancer (NSCLC) that has a KRAS G12C mutation. It’s mainly testing safety and how well the treatments work after the cancer has progressed despite prior anti–PD-1 treatment.
Garden City, New YorkAges 18–100 - NCT06579612Recruiting
Personalized exercise support for chronic lung disease
This trial tests whether one-on-one guidance from a sports-health specialist can improve your well-being if you have a chronic lung condition like asthma, COPD, or sleep apnea and are already taking part in a lung rehabilitation program.
BrestAges 18–80 - NCT06816342RecruitingPhase 4
Emergency spacers vs. traditional spacers for asthma
This trial tests whether an emergency-use spacer works as well as a traditional spacer for delivering asthma medication through an inhaler. It may help people with mild to moderate asthma breathe better during an attack.
Banī Suwayf, EgyptAges 6–80 - NCT06582771RecruitingPhase 2
Testing sotorasib for untreated lung cancer with KRAS G12C mutation
This trial tests an oral targeted drug called sotorasib for people with a specific type of advanced lung cancer (KRAS G12C mutation) who have not had any prior treatment for their advanced disease. It aims to see if this drug can shrink tumors and help patients without using standard chemotherapy or immunotherapy first.
Basking Ridge, New JerseyAges 18 years+ - NCT07029841Recruiting
Catheter therapy study for acute pulmonary embolism patients
This study follows patients in Hong Kong who are treated with catheter-based therapy for acute pulmonary embolism. It aims to understand how well this treatment works.
Hong Kong, Hong KongAges 18 years+ - NCT06584604Recruiting
Calibrating esophageal balloon for breathing machine patients
This trial is testing how to calibrate an esophageal balloon (a thin tube that measures pressure in your chest) for people on a breathing machine. If you are already sedated and have this tube in place, participating may help doctors get more accurate readings to improve your breathing support.
Leiden, South HollandAges 18 years+ - NCT07024095Recruiting
Breathing muscle training after back surgery for osteoporosis
This study tests whether a simple breathing-muscle training program can help people recover better after vertebroplasty surgery for a broken back caused by osteoporosis. It aims to improve your breathing strength and overall function.
Kayseri, KocasinanAges 50 years+ - NCT06950112Recruiting
Comparing two breathing methods for obese patients during weight-loss surgery
This trial tests a personalized way of setting the breathing machine during weight-loss surgery to reduce lung stress. It compares a tailored approach with standard care in people with obesity.
Tanta, El GharbiaAges 18–60 - NCT06741085RecruitingPhase 2
Radiosurgery plus standard care for lung cancer spread to brain
This trial tests if adding stereotactic radiosurgery (focused radiation) to standard drug therapy is safe and effective for people with EGFR-mutant non-small cell lung cancer that has spread to the brain. It aims to improve control of brain metastases while continuing targeted therapy.
Miami, FloridaAges 18 years+ - NCT07747337Recruiting
Lung transplant recovery study
This study looks at how your breathing muscles and leg muscles work before and after a lung transplant. It may help doctors understand how to improve recovery and physical function after surgery.
Gainesville, FloridaAges 18 years+ - NCT07016685Recruiting
ECMO outcomes after emergency chest surgery
This study looks at how well patients recover after needing a heart-lung bypass machine (VV-ECMO) during or right after emergency chest surgery. It aims to understand what affects their prognosis.
AmiensAges 18 years+ - NCT07016022Recruiting
Heart and lung test before chest surgery helps predict risks
This study checks if a simple test of your heart and breathing before chest surgery can help predict problems after the operation. It looks at people having surgery for lung, esophagus, stomach, or chest tumors.
Ottawa, OntarioAges 18 years+ - NCT05994131RecruitingPhase 1/Phase 2
IN10018 plus targeted therapy for EGFR-mutant lung cancer
This trial tests a new drug called IN10018 combined with a targeted therapy (third-generation EGFR-TKI) for people with advanced EGFR-mutant non-small cell lung cancer. It's designed for different stages of treatment, from first-time therapy to after other treatments have stopped working.
ShanghaiAges 18 years+ - NCT07014124Recruiting
Helping smoking fathers quit for their sick child
This study tests whether helping smoking fathers quit can improve their child's health. You and your child will get support through a messaging app, and the child will provide saliva samples.
Hong Kong, PokfulamAges 18 years+ - NCT07011069Recruiting
Comparing two pain blocks for lung surgery recovery
This trial tests two nerve-block methods to see which provides better pain control after minimally invasive lung surgery (VATS). If you qualify, you would receive one of the blocks to help reduce pain and possibly speed recovery.
Bursa, NiluferAges 18–80 - NCT07005193Recruiting
Cleaner cooking and ventilation for better heart and lung health
This study tests if switching to cleaner LPG gas stoves and adding kitchen fans can reduce indoor air pollution and improve your heart and lung health. You would be asked to use a new stove and fan, and we will check your health over time.
Zhumadian, HenanAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.